Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,269 recruiting studies in this area right now.
By phase
- Not applicable890
- Phase 2154
- Phase 3103
- Phase 147
- Phase 431
- Phase 1/Phase 230
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma73
- Dysphagia66
- Hearing Loss61
- Tinnitus29
- Hearing Loss, Sensorineural24
- Nasopharyngeal Carcinoma (NPC)24
- Head and Neck Cancer23
- Allergic Rhinitis22
- Oropharynx Cancer21
- Nasopharyngeal Cancinoma (NPC)18
- Sensorineural Hearing Loss18
- Stroke17
- Oropharyngeal Cancer14
- Vestibular Schwannoma14
- Chronic Rhinosinusitis With Nasal Polyps13
- Deafness13
- Head and Neck Squamous Cell Carcinoma13
- Nasopharyngeal Cancer13
Leading sponsors
- Sun Yat-sen University57
- Assistance Publique - Hôpitaux de Paris14
- Eye & ENT Hospital of Fudan University14
- National Cancer Institute (NCI)14
- Cairo University13
- NYU Langone Health13
- Mayo Clinic12
- Johns Hopkins University11
- Ming-Yuan Chen11
- Massachusetts Eye and Ear Infirmary10
Where studies are running
- California61
- Maryland38
- Florida32
- New York32
- Massachusetts24
- Illinois20
- Texas20
- Alabama15
- Arizona15
- Colorado15
Recruiting studies1,269 total
- NCT06462417Recruiting
Testing arbidol for allergic rhinitis
This trial tests if arbidol, an antiviral medicine, can safely treat allergic rhinitis (hay fever). It might help if your nasal symptoms like sneezing or stuffiness are moderate to severe.
Wuhan, HubeiAges 18–65 - NCT06398873Recruiting
Dupilumab and nasal lining in chronic sinusitis with polyps
This study tests whether dupilumab, a medication given as an injection, helps improve the lining of the nose in people with chronic sinus inflammation and nasal polyps. If you have nasal polyps and are about to start dupilumab, or if you have sinusitis without polyps, you may be eligible to join.
Vienna, AustriaAges 18–99 - NCT06960876Recruiting
Ultrasound vs. sinus massage for chronic sinusitis
This study compares two treatments for chronic sinusitis: ultrasound therapy (sound waves applied to the face) and sinus massage (gentle pressure on the face). Both are non-drug options that may help relieve your symptoms.
IslamabadAges 20–60 - NCT06960772Recruiting
Flow ball phonation for voice professionals
This trial tests whether a device called a flow ball can help professional voice users with functional voice disorders improve their voice or prevent voice disorders. You blow into the ball to make it float while making sounds, which may strengthen your voice.
Ghent, East-FlandersAges 18–60 - NCT07137052Recruiting
Precise adaptive radiotherapy for nasopharyngeal cancer
This trial tests a more precise form of radiation therapy (adaptive radiotherapy) for nasopharyngeal cancer. It is designed for patients who have not yet had any treatment and whose cancer is limited to the head and neck area.
XiamenAges 18–70 - NCT07130136Recruiting
Switching from Baha Connect to Osia for bone conduction implant users
This study is for people who already have a Baha Connect bone conduction hearing implant but are having problems with it, like skin irritation. It tests switching to a newer device called Osia, which may work better for them.
LondonAges 18 years+ - NCT07132827RecruitingPhase 3
Study of SHR-1905 for chronic sinusitis with nasal polyps
This trial tests a new injection (SHR-1905) for people with chronic sinusitis and nasal polyps who still have symptoms despite using standard nasal spray treatments. It aims to see if the drug can reduce polyp size and improve symptoms.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07131800Enrolling by invitation
Voice changes after breathing tube in head and neck surgery
This study looks at how your voice may change after a breathing tube is used during surgery. It focuses on people having thyroid, head and neck, or abdominal surgery to see if there are any voice changes that can be measured or noticed.
ZagrebAges 18–70 - NCT07116135Recruiting
Hearing aid benefits on speech understanding and listening effort
This trial tests whether a new hearing instrument improves your ability to understand speech and reduces the mental effort of listening. If you are an experienced hearing aid user with moderate to moderately severe hearing loss, you may be eligible.
Tampa, FloridaAges 18–95 - NCT07125755RecruitingPhase 3
Comparing Chemo plus Radiation vs. Radiation Alone for Head and Neck Cancer
This trial tests whether adding chemotherapy to radiation therapy after surgery can help prevent head and neck cancer from coming back. It is for people who have certain risk factors after their surgery but no signs of cancer spread.
Guangzhou, GuangdongAges 18–70 - NCT07118579RecruitingPhase 4
Comparing two anesthesia drugs for kids' tonsil surgery
This study compares two newer sedation drugs (remimazolam and ciprofol) to see which one better prevents breathing or airway problems during and after tonsil surgery in children.
Wuhan, HubeiAges 2–12 - NCT07125586Recruiting
Light-based test for eosinophilic nasal polyps during surgery
This study tests a new tool that uses light (spectroscopy) to instantly detect a type of nasal polyp during surgery. The goal is to help doctors identify polyps that are driven by eosinophils, which may guide better treatment choices for you.
Qingdao, ShandongAges 18–65 - NCT07124650RecruitingPhase 4
Sore throat after neck surgery study
This study tests if a special spray can help prevent or reduce sore throat after thyroid or parathyroid surgery. It may help you feel more comfortable after your operation.
Saint PetersburgAges 18 years+ - NCT04435990RecruitingPhase 3
Allergy shots for dust mites in teens and adults
This Phase 3 study tests whether dust-mite allergy treatment (likely allergy shots) can reduce allergy symptoms and improve safety. It focuses on people whose nose/eye allergy is triggered by house dust mites and who may also have controlled asthma.
Santiago de Compostela, A CoruñaAges 12–65 - NCT04898283RecruitingPhase 3
Allergy shot study for grass and cypress pollen symptoms
This phase 3 trial tests a specific allergy treatment (an “immunotherapy” shot) for people whose symptoms are triggered by grass and cypress tree pollen. It aims to see if the treatment is safer and more effective at reducing allergy symptoms over time, especially for nose/eye symptoms and some people with asthma.
Valladolid, Castille and LeónAges 12–65 - NCT06226558Recruiting
Long-Term Health of Children with Congenital CMV in NY
This study will follow children born in New York State who were tested for cytomegalovirus (CMV) as newborns. It aims to understand their long-term health and development, whether they were confirmed to have CMV, a false positive, or even a late detection if born early.
Stony Brook, New YorkAges birth–1 year - NCT07107256RecruitingPhase 3
Study of TQC2731 for chronic sinusitis with nasal polyps
This trial tests an injectable drug called TQC2731 for people with chronic sinusitis and nasal polyps that haven't been controlled well enough by standard treatments like steroid sprays or surgery. The goal is to see if it helps reduce nasal congestion, improve sense of smell, and shrink polyps.
Fuyang, AnhuiAges 18–75 - NCT07114744Recruiting
Early cochlear implant use trial
This trial studies how well people new to cochlear implants understand speech over time. It may help you if you have severe hearing loss and are about to get a cochlear implant for the first time.
New York, New YorkAges 18–85 - NCT07111000Recruiting
Epley maneuver for dizziness in the emergency room
This study tests whether a simple head movement called the Epley maneuver can help treat dizziness caused by a common inner ear condition (BPPV) in the emergency room. If you have short episodes of vertigo that last less than 2 minutes, you may be able to join.
BeirutAges 18 years+ - NCT07106593Recruiting
Talk therapy for PTSD and tinnitus after concussion
This study tests a type of talk therapy for people with both PTSD and chronic tinnitus that started after a mild head injury. The therapy aims to help reduce symptoms of both conditions together.
San Antonio, TexasAges 18 years+ - NCT07114133Enrolling by invitation
Environmental probiotics for cat hair allergies
This study tests whether a special probiotic spray, used in your home, can reduce allergy symptoms in people who are allergic to cats. If you have cat allergies with nasal symptoms and live in a stable home, you may be able to join.
Hangzhou, ZhejiangAges 18–70 - NCT07110311Recruiting
How pet cats affect nose and gut bacteria in cat allergy patients
This study looks at how living with a pet cat might affect the bacteria in your nose and gut if you have dust mite and cat allergies. It could help us understand if cats actually change your allergy symptoms or the balance of bugs in your body.
Nanjing, JiangsuAges 18–65 - NCT07115342Recruiting
Probiotics and vitamin D for hay fever relief
This study tests whether taking a combination of probiotics (good bacteria) and vitamin D can help reduce hay fever symptoms. It may be a good option if your vitamin D is low and you haven't used probiotics recently.
Tanta, Gharbia GovernorateAges 18–65 - NCT06966518Recruiting
Ketamine and magnesium for pain control after nose surgery
This study tests whether giving a combination of two medicines (ketamine and magnesium sulfate) during nose surgery can help reduce pain after the operation. It may be a good option for healthy adults having rhinoplasty and looking for better pain control.
CairoAges 18–65
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,269 recruiting otolaryngology studies from the U.S. registry right now, out of 2,074 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.