Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,269 recruiting studies in this area right now.
By phase
- Not applicable890
- Phase 2154
- Phase 3103
- Phase 147
- Phase 431
- Phase 1/Phase 230
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma73
- Dysphagia66
- Hearing Loss61
- Tinnitus29
- Hearing Loss, Sensorineural24
- Nasopharyngeal Carcinoma (NPC)24
- Head and Neck Cancer23
- Allergic Rhinitis22
- Oropharynx Cancer21
- Nasopharyngeal Cancinoma (NPC)18
- Sensorineural Hearing Loss18
- Stroke17
- Oropharyngeal Cancer14
- Vestibular Schwannoma14
- Chronic Rhinosinusitis With Nasal Polyps13
- Deafness13
- Head and Neck Squamous Cell Carcinoma13
- Nasopharyngeal Cancer13
Leading sponsors
- Sun Yat-sen University57
- Assistance Publique - Hôpitaux de Paris14
- Eye & ENT Hospital of Fudan University14
- National Cancer Institute (NCI)14
- Cairo University13
- NYU Langone Health13
- Mayo Clinic12
- Johns Hopkins University11
- Ming-Yuan Chen11
- Massachusetts Eye and Ear Infirmary10
Where studies are running
- California61
- Maryland38
- Florida32
- New York32
- Massachusetts24
- Illinois20
- Texas20
- Alabama15
- Arizona15
- Colorado15
Recruiting studies1,269 total
- NCT07175779Recruiting
Comparing video calls vs. in-person visits for kids' surgery checkups
This trial tests whether a video call before surgery works as well as an in-person hospital visit for checking breathing risks in children getting their tonsils or adenoids removed. It may help families avoid extra trips to the hospital.
Bellinzona, Canton TicinoAges Up to 16 years - NCT07176988Recruiting
Voice therapy study for certain voice problems
This study tests a behavioral voice therapy approach for people with voice issues caused by muscle tension or benign vocal fold lesions. It aims to improve communication and requires participants to attend sessions and practice with a smartphone.
Atlanta, GeorgiaAges 16–65 - NCT06098482Recruiting
Testing speech understanding with a mobile app for hearing device users
This study uses a smartphone app to test how well adults who use hearing aids or cochlear implants can understand speech. It aims to see if the app is a reliable way to measure hearing performance, which could make future check-ups easier and more convenient.
Lone Tree, ColoradoAges 18 years+ - NCT07174115RecruitingPhase 2
Testing a new tablet for chronic sinusitis without nasal polyps
This trial tests an experimental tablet (HTMC0658) for people with chronic sinusitis that hasn't improved with standard nasal spray. You may join if your symptoms are moderate to severe and you've been using a stable dose of mometasone spray for at least 4 weeks.
Luoyang, HenanAges 18–75 - NCT07168473RecruitingPhase 3
A study of DW1807 for year-round allergies and asthma
This trial tests a new medicine called DW1807 for people who have both year-round allergies (like dust mites or pet dander) and asthma. It aims to see if it helps control nasal symptoms and is safe to use.
SeoulAges 19 years+ - NCT05532566Recruiting
Tested oak tree allergy extracts for people with inhalant allergy
This trial studies how well standardized oak (Quercus ilex and Quercus robur) allergen extracts match your specific allergy. It may help refine allergy testing and treatment planning for people with oak-triggered rhinitis, eye symptoms, and/or asthma.
MadridAges 18–64 - NCT06664710Recruiting
Robot-assisted cochlear implant surgery with hearing monitoring
This study tests a new robotic system that helps place a cochlear implant while measuring your inner ear's natural electrical signals during surgery. The goal is to make the procedure more precise and possibly improve hearing outcomes.
Iowa City, IowaAges 12 years+ - NCT07156227RecruitingPhase 1
Testing camonsertib with radiation for returning head and neck cancer
This study tests whether adding the drug camonsertib to radiation therapy can help people whose head and neck cancer has come back in a spot that was already treated with radiation. Camonsertib is an experimental drug that may help radiation work better.
Duarte, CaliforniaAges 18 years+ - NCT07156825Recruiting
Adapting hearing tests for children in different languages
This study aims to adapt hearing tests used for children into other languages. It may help improve how hearing loss is diagnosed in children who speak languages other than English.
BudapestAges 2–7 - NCT06591793RecruitingPhase 1/Phase 2
Gene therapy for Usher syndrome type 1B vision loss
This trial tests an experimental gene therapy given as an injection under the retina. It aims to slow or stop vision loss in people with Usher syndrome type 1B, a rare genetic condition that causes both hearing and vision problems.
NaplesAges 18–50 - NCT07149428Recruiting
Deep study of smell loss causes using brain scans
This study uses brain imaging and electrical recordings to understand the brain's role in smell loss from any cause—like COVID, sinus problems, or chemotherapy. You may be eligible if you have any degree of smell loss lasting under a year.
Bethesda, MarylandAges 18–99 - NCT07146256Recruiting
OPMD Natural History Registry Study
This study is building a national registry (a database) for people with Oculo-Pharyngeal Muscular Dystrophy (OPMD) in Israel. Joining will help researchers understand how OPMD progresses over time and may lead to better care.
Ramat GanAges 18 years+ - NCT07154342RecruitingPhase 3
Testing a new antibody for seasonal allergies
This trial tests an experimental antibody (IL4Rα monoclonal antibody) for people with seasonal allergic rhinitis (hay fever) that is not well controlled by standard treatments like nasal steroid sprays. The goal is to see if this new treatment can help reduce allergy symptoms during pollen season.
Wuhan, HubeiAges 18–75 - NCT07146607Recruiting
Text messages to support new hearing aid users
This trial tests if sending text messages helps adults who just got their first hearing aid use it better. You might benefit if you have a mobile phone and are starting with NHS hearing aids.
Nottingham, NottinghamshireAges 18 years+ - NCT07154667Recruiting
Testing a new ear reconstruction system in children
This trial is testing a new device called the Auryzon EAR 2.0 System to help rebuild ears in children and teens who have a deformity from birth or injury. The goal is to see if it works well for patients having surgery at Nemours Children's Hospital in Florida.
Orlando, FloridaAges 5–20 - NCT07145086RecruitingPhase 3
Vibration therapy for voice problems
This trial tests if gentle vibration applied to the neck can help people with voice problems caused by muscle strain (hyperfunctional dysphonia). If you have a strained voice without vocal cord lesions and may benefit from voice therapy, this study could help you.
Fort Worth, TexasAges 18 years+ - NCT07154069RecruitingPhase 3
Immunotherapy for advanced nasopharyngeal cancer after chemo
This trial tests if adding an immunotherapy drug (PD-1 inhibitor) after standard induction chemotherapy helps keep advanced nasopharyngeal cancer from coming back. It is for people who have completed 3 cycles of GP chemotherapy combined with a PD-1 inhibitor and have not had their cancer progress.
Guangzhou, GuangdongAges 18–65 - NCT07154121Recruiting
5-FU added to tear duct surgery for small tear sacs
This study tests if adding a medicine called 5-FU to standard tear duct surgery helps people with a small tear drainage sac get better results. It might be an option if you have a blocked tear duct and a very small sac.
Guangzhou, GuangdongAges 18 years+ - NCT07147426RecruitingPhase 2
Tislelizumab plus chemo before surgery for head and neck cancer
This trial tests whether giving the immunotherapy drug tislelizumab with chemotherapy before surgery can help people with advanced head and neck cancer. The goal is to shrink the tumor enough to remove it completely during surgery.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT07146841Recruiting
Preserving hearing during cochlear implant surgery
This study tests a surgical technique designed to preserve as much natural hearing as possible during cochlear implant surgery. It is for people with severe hearing loss who choose an Advanced Bionics implant and are comfortable speaking Dutch.
UtrechtAges 18 years+ - NCT07153692Recruiting
Brain stimulation for swallowing problems in Parkinson's
This study is testing whether a gentle brain-stimulation technique called tDCS can help people with Parkinson's disease who have trouble swallowing. If you have Parkinson's, multiple system atrophy, or progressive supranuclear palsy and a swallowing problem, this trial may be an option.
Hangzhou, ZhejiangAges 18–100 - NCT06953414Recruiting
Predicting difficult awake breathing tube placement
This study tests a way to predict which patients will have a hard time placing a breathing tube while they are awake, using a flexible scope. It aims to help doctors plan safer procedures for people with known difficult airways.
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT04891237RecruitingPhase 3
Grass and olive allergy vaccine trial for teens to older adults
This Phase 3 trial tests whether an allergy treatment can reduce symptoms caused by grass and olive pollen. It also checks safety, especially for breathing and allergic reactions, in people with confirmed grass/olive allergy.
Tarancón, CuencaAges 12–65 - NCT05009758Recruiting
Asthma and nasal polyps study to match immune patterns
This study looks at different “immune inflammation patterns” in people with asthma and/or nasal polyps. It may help researchers better tailor future treatments by figuring out which patterns go with which symptoms.
ViennaAges 18–99
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,269 recruiting otolaryngology studies from the U.S. registry right now, out of 2,074 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.