Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,371 recruiting studies in this area right now.
By phase
- Not applicable978
- Phase 2168
- Phase 399
- Phase 146
- Phase 434
- Phase 1/Phase 232
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma80
- Dysphagia73
- Hearing Loss61
- Tinnitus31
- Hearing Loss, Sensorineural25
- Nasopharyngeal Carcinoma (NPC)24
- Allergic Rhinitis23
- Head and Neck Cancer22
- Oropharynx Cancer21
- Stroke20
- Sensorineural Hearing Loss18
- Nasopharyngeal Cancinoma (NPC)17
- Chronic Rhinosinusitis With Nasal Polyps15
- Oropharyngeal Cancer15
- Nasopharyngeal Cancer14
- Vestibular Schwannoma14
- Head and Neck Squamous Cell Carcinoma13
- Chronic Rhinosinusitis (CRS)12
Leading sponsors
- Sun Yat-sen University59
- Eye & ENT Hospital of Fudan University17
- Cairo University15
- Assistance Publique - Hôpitaux de Paris14
- NYU Langone Health14
- Mayo Clinic12
- National Cancer Institute (NCI)12
- Johns Hopkins University11
- Ming-Yuan Chen11
- Cochlear9
Where studies are running
- California62
- Maryland37
- New York35
- Florida30
- Massachusetts21
- Illinois20
- Texas18
- Arizona17
- Colorado16
- Alabama15
Recruiting studies1,371 total
- NCT06517888RecruitingPhase 1/Phase 2
Gene therapy for hearing loss from vestibular schwannoma
This trial tests a gene therapy injected into the ear to slow tumor growth and prevent further hearing loss in people with a vestibular schwannoma that is getting worse. It's for those who already have severe hearing loss in the affected ear.
Baltimore, MarylandAges 18 years+ - NCT06520579Recruiting
Behavioral help before and after neck surgery
This trial tests if a simple behavioral program can help adults prepare for and recover from anterior neck surgery (ACDF). It includes extra support and nutrition tips to improve healing.
New York, New YorkAges 21–99 - NCT06523478Recruiting
Tonsil injection allergy shots for hay fever
This trial tests a new way to treat allergies by injecting allergy medicine directly into the tonsils. It may help people with hay fever who haven't gotten relief from standard treatments or want to avoid long-term medication.
Wuhan, HubeiAges 5–65 - NCT06524193Recruiting
Comparing in-person vs online voice therapy for voice strain
This study compares the effectiveness of face-to-face voice therapy versus online voice therapy for muscle tension dysphonia (a voice disorder from throat muscle strain). It tests whether doing therapy via video call works just as well as in-person sessions.
Hong KongAges 18 years+ - NCT06525220RecruitingPhase 3
New drug combo vs. standard for head and neck cancer
This trial tests a new combination of two immunotherapy drugs (petosemtamab plus pembrolizumab) compared to pembrolizumab alone for people with head and neck cancer that has spread or come back and cannot be cured locally. It may be an option if your cancer has a certain protein (PD-L1) and you haven't had prior cancer treatment for this stage.
Mobile, AlabamaAges 18 years+ - NCT06525597RecruitingPhase 2
Stapokibart injection for allergic rhinitis
Stapokibart is a new injection that works on a key pathway involved in allergy symptoms. This study will test if this once-every-two-week shot can help reduce runny nose, sneezing, and itchy eyes in people with allergic rhinitis (hay fever).
Beijing, Beijing MunicipalityAges 12–65 - NCT06529562Recruiting
Surgery plus reduced chemo and radiation vs standard for nasopharyngeal cancer
This trial compares two approaches for people with early-stage nasopharyngeal cancer that can be removed with surgery. It tests whether giving less intense chemotherapy and radiation after surgery works as well as a standard dose, with fewer side effects.
Zhuhai, GuangdongAges 18–70 - NCT06530069Recruiting
Fungal Ear Infection Risk Factors Study
This study looks for causes of fungal ear infections (otomycosis) by comparing people with active infections to those without ear symptoms. You may join if you have ear symptoms and a confirmed fungal infection in your ear canal.
Xiamen, FujianAges Any age - NCT06531577Recruiting
Weather and nosebleed study for Ankara residents
This study looks at whether changes in air pressure are linked to nosebleeds. It involves people living in Ankara who come to the emergency department with a nosebleed.
Ankara, YenimahalleAges 18 years+ - NCT06532279RecruitingPhase 2
Testing BMX-001 with chemoradiation for head and neck cancer
This trial tests whether adding BMX-001 (a drug that may protect healthy tissues) to standard chemoradiation can reduce side effects and improve outcomes for people with head and neck cancer. It's a randomized study, so you would have a 50/50 chance of getting BMX-001 or a placebo.
Gilbert, ArizonaAges 18 years+ - NCT06533267Recruiting
Endoscopic surgery vs. radiation for early-stage nasal cancer
This trial compares two treatments for stage I nasopharyngeal cancer (a type of nasal cancer). It tests whether a minimally invasive surgery (endoscopic surgery) is as good as or better than radiation therapy. It may be an option for people whose cancer is small and hasn't spread to lymph nodes.
Zhuhai, GuangdongAges 18–75 - NCT06535087Recruiting
How airway allergies affect children and parents' quality of life
This study looks at how airway allergies (like asthma and hay fever) affect the daily life of children and their parents. By filling out a questionnaire, you can help researchers understand these challenges and find better ways to support families.
Shanghai, Shanghai MunicipalityAges 5–16 - NCT06543316Recruiting
Treating gastric bypass ulcers with low-thermal argon plasma
This study tests a new way to treat painful sores (marginal ulcers) that can happen after gastric bypass surgery. Doctors use a special tool (argon plasma) during an endoscopy to help the sores heal faster, and you will get standard ulcer medicine too.
Boston, MassachusettsAges 18 years+ - NCT06544434RecruitingPhase 2
Laser acupuncture for Meniere disease
This trial tests if laser acupuncture can help people with Meniere disease, a condition that causes dizziness, hearing loss, and ringing in the ears. It compares laser acupuncture to a placebo to see if it reduces symptoms.
BeijingAges 18–65 - NCT06547372Recruiting
Dietary changes for eczema relief
This study tests whether a specific diet can help manage mild to moderate eczema. It involves eating whole foods provided by the researchers for a set period and tracking your skin health.
Singapore, SingaporeAges 21–65 - NCT06551857Recruiting
How cancer treatments affect hearing and thinking
This study looks at how common cancer treatments (certain chemotherapies and radiation to the head and neck) affect hearing in noisy places, thinking skills, and quality of life related to hearing. It aims to understand and possibly reduce these side effects.
Turku, Southwest FinlandAges 18–75 - NCT06554158Recruiting
Lowering radiation for low-risk HPV throat cancer patients
This trial tests whether giving less radiation after surgery is safe and effective for people with early-stage HPV-related throat cancer. It aims to reduce side effects while still controlling the cancer.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06560255RecruitingPhase 3
Fish oil in pregnancy to prevent childhood asthma
This study tests if taking fish oil during pregnancy can help lower the risk of childhood asthma. If you have low omega-3 levels, you may be randomly assigned to receive fish oil or a placebo.
Gentofte MunicipalityAges 18–45 - NCT06570889RecruitingPhase 3
Vitamin D in pregnancy to prevent early childhood asthma
This trial tests if taking extra vitamin D during pregnancy can prevent asthma in young children. It is for pregnant women in Denmark who already have certain healthy fat levels in their blood.
Gentofte MunicipalityAges 18–45 - NCT06572475Recruiting
New MRI contrast for brain tumors
This trial uses a new type of MRI contrast dye (USPIO) to get clearer images of certain slow-growing brain tumors (vestibular schwannomas and low-grade gliomas). The goal is to see if this dye helps doctors better understand and treat these tumors.
Salford, Greater ManchesterAges 16–100 - NCT06576830RecruitingPhase 4
Pain relief study for kids having tonsil surgery
This study tests different ways to manage pain after tonsillectomy in children. The goal is to find better pain relief options.
Durham, North CarolinaAges 3–17 - NCT06580847Recruiting
Choir for older adults with untreated hearing loss
This trial tests whether joining a choir helps older adults with untreated hearing loss. If you have mild-to-moderate hearing loss and do not use hearing aids, this study may be a good fit for you.
Los Angeles, CaliforniaAges 60 years+ - NCT06591793RecruitingPhase 1/Phase 2
Gene therapy for Usher syndrome type 1B vision loss
This trial tests an experimental gene therapy given as an injection under the retina. It aims to slow or stop vision loss in people with Usher syndrome type 1B, a rare genetic condition that causes both hearing and vision problems.
NaplesAges 18–50 - NCT06592599RecruitingPhase 2
Drug combo for EBV-related nasopharyngeal cancer
This trial tests a combination of three drugs (gemcitabine, docetaxel, and toripalimab) as a first treatment for a type of nasopharyngeal cancer linked to the Epstein-Barr virus. The goal is to see if this combination helps shrink tumors before other treatments like radiation.
Palo Alto, CaliforniaAges 18 years+
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,371 recruiting otolaryngology studies from the U.S. registry right now, out of 2,216 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.