Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,269 recruiting studies in this area right now.
By phase
- Not applicable890
- Phase 2154
- Phase 3103
- Phase 147
- Phase 431
- Phase 1/Phase 230
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma73
- Dysphagia66
- Hearing Loss61
- Tinnitus29
- Hearing Loss, Sensorineural24
- Nasopharyngeal Carcinoma (NPC)24
- Head and Neck Cancer23
- Allergic Rhinitis22
- Oropharynx Cancer21
- Nasopharyngeal Cancinoma (NPC)18
- Sensorineural Hearing Loss18
- Stroke17
- Oropharyngeal Cancer14
- Vestibular Schwannoma14
- Chronic Rhinosinusitis With Nasal Polyps13
- Deafness13
- Head and Neck Squamous Cell Carcinoma13
- Nasopharyngeal Cancer13
Leading sponsors
- Sun Yat-sen University57
- Assistance Publique - Hôpitaux de Paris14
- Eye & ENT Hospital of Fudan University14
- National Cancer Institute (NCI)14
- Cairo University13
- NYU Langone Health13
- Mayo Clinic12
- Johns Hopkins University11
- Ming-Yuan Chen11
- Massachusetts Eye and Ear Infirmary10
Where studies are running
- California61
- Maryland38
- Florida32
- New York32
- Massachusetts24
- Illinois20
- Texas20
- Alabama15
- Arizona15
- Colorado15
Recruiting studies1,269 total
- NCT06510972Recruiting
Eating versus fasting for ICU patients with breathing failure
This study looks at whether it's safe and helpful to let people with severe breathing problems in the ICU eat and drink normally instead of fasting. If you qualify, you may be assigned to either continue eating or to fast while doctors monitor your recovery.
BloisAges 18 years+ - NCT06507709Enrolling by invitation
Sinus lift study using a special bone graft putty
This study tests a new type of bone graft putty for people who need a sinus lift before getting dental implants. It may be an option if you have some existing bone and are generally healthy or have well-controlled diabetes.
San Antonio, TexasAges 18–85 - NCT06479811RecruitingPhase 1
Radioactive drug for advanced neuroendocrine and other cancers
This early-stage trial tests a new radioactive drug (called [212Pb]VMT-Alpha-NET) that targets a marker on certain cancer cells. It may help shrink or slow the growth of tumors that have spread or can't be removed, and it's being studied for several cancer types, including neuroendocrine tumors, small cell lung cancer, kidney cancer, and some head and neck cancers.
Bethesda, MarylandAges 18–120 - NCT06495021Recruiting
Osteopathic manipulation for newly diagnosed respiratory illness in older adults
This study tests whether osteopathic manipulation (a gentle hands-on treatment) helps older adults recover from common respiratory illnesses like bronchitis or pneumonia when added to regular care. It may be a good option for you if you're 65 or older and have just been diagnosed with a respiratory infection.
Bloomsburg, PennsylvaniaAges 65–100 - NCT06475300RecruitingPhase 2
BL-B01D1 plus immunotherapy for advanced lung and throat cancers
This trial tests a new combination treatment (BL-B01D1 plus a PD-1 inhibitor) for people with advanced lung cancer or nasopharyngeal cancer. It aims to see if the combination is safe and effective for patients whose cancer has not responded to earlier treatments.
Guangzhou, GuangdongAges 18 years+ - NCT06464198Recruiting
Radiation and chemo after surgery for salivary gland cancer
This study tests giving radiation and chemotherapy together after surgery for aggressive salivary gland cancers of the head and neck. It aims to see how well this standard treatment works in real-world settings.
ErlangenAges 18–99 - NCT06475365Enrolling by invitation
Salt water gargling after neck surgery to help swallowing
This study tests whether gargling with salt water after multi-level neck fusion surgery can improve swallowing recovery. If you are having this surgery, the trial aims to find a simple, low-cost way to protect your swallowing function.
Los Angeles, CaliforniaAges 18–80 - NCT06475651Recruiting
DNA patterns in rare prenatal diseases
This study looks at DNA patterns in fetuses or children with rare genetic conditions. It aims to better understand how these patterns relate to diseases that start before birth, which could help with diagnosis and future care.
ParisAges birth–18 years - NCT06465979Recruiting
How do people with hearing loss understand speech in different settings?
This study looks at how people with healthy hearing or hearing loss understand speech in different listening environments. You might join if you have normal hearing, mild hearing loss, or use a cochlear implant, and are a competent adult English speaker.
Minneapolis, MinnesotaAges 18–65 - NCT06457503RecruitingPhase 4
Toripalimab plus chemo for advanced nasopharyngeal cancer
This trial tests whether adding the immunotherapy drug toripalimab to standard chemotherapy (cisplatin and gemcitabine) can help people whose nasopharyngeal cancer has come back or spread. It is for those who haven't yet received other treatments for this advanced stage.
Little Rock, ArkansasAges 12 years+ - NCT04707885Recruiting
Testing how much residual hearing helps with cochlear implants
This study looks at whether keeping some natural (residual) hearing in the implant ear can improve outcomes with a cochlear implant. If you fit their hearing and implant-device requirements, they’ll measure your hearing before and after implantation to see how well you can use that remaining hearing.
Rochester, MinnesotaAges 18–79 - NCT06445114RecruitingPhase 2
Blood-Guided Chemoradiation for HPV-Positive Throat Cancer
This study tests whether a blood test that looks for circulating HPV DNA (ctDNA) can help doctors decide if you need chemotherapy after surgery for HPV-positive throat cancer. After you have surgery to remove the cancer, you receive radiation (possibly with chemotherapy) — the results of the blood test guide whether or not to add chemo.
Beverly Hills, CaliforniaAges 18 years+ - NCT05917496Recruiting
Support study for families after early cochlear implants
This study looks at how parent support helps children who get cochlear implants very early, and how well their language develops. You may be able to join if your child meets the timing and hearing/implant requirements and you speak French at home.
ParisAges 11 months–1.8 years - NCT06051006Recruiting
Testing Cochlear Implant Settings in Teens
This study tests a method to set cochlear implant sound levels using a small reflex in the ear. It may help doctors find the best sound settings for users aged 8-17.
ParisAges 8–17 - NCT05757817Recruiting
New flap surgery for mouth or throat cancer reconstruction
This trial studies whether a new surgical reconstruction method can improve outcomes for people with oral cavity or oropharyngeal squamous cell carcinoma (a type of head and neck cancer). The goal is to rebuild the area using a tissue flap while reducing problems where the tissue is taken from.
MontpellierAges 18 years+ - NCT06430957Recruiting
Sleep apnea risk after dental surgery under general anesthesia
This study checks dental patients for the risk of sleep apnea before surgery and looks at whether that risk is linked to problems after general anesthesia. It may help you understand your own risk and improve safety.
KayseriAges 18–80 - NCT06436534Recruiting
Ganciclovir for stubborn allergic rhinitis
This study tests whether an antiviral medicine called ganciclovir (in capsule form) can help people with stubborn moderate-to-severe allergic rhinitis that doesn't improve with standard treatments. If you have year-round allergies to dust mites and your symptoms are still bothersome, this trial may be an option for you.
Wuhan, HubeiAges 18–65 - NCT06431698Recruiting
Correcting ear shapes in newborns: comparing two methods
This trial tests two different ways to mold and fix ear deformities in newborns. If successful, your baby could have a more normally shaped ear without surgery.
Caen, NAges Up to 1 month - NCT06406725Recruiting
Detecting vocal cord issues with noninvasive breathing test
This study tests whether a noninvasive breathing support device can detect vocal cord movement problems in children who had heart or airway surgery. It may avoid the need for a scope test.
Queens, New YorkAges 1 day–18 years - NCT06407102Recruiting
Nose or sinus tissue collection during surgery
This trial collects a small sample of tissue from your nose or sinus during a planned surgery. The sample is used for research to better understand diseases of the nose and sinuses.
ToursAges 18–90 - NCT06400992Recruiting
Testing Sky hearing technology in children
This study is testing the Sky CI sound processor in children aged 6–16 who use cochlear implants and/or hearing aids. The goal is to see how well the Sky technology works for hearing in noise.
ParisAges 6–16 - NCT06408363Recruiting
Ear pressure maneuvers for first hyperbaric session
This trial looks at whether doing a specific sequence of ear pressure-equalization moves helps people during their first hyperbaric oxygen therapy session. It might help you if you're about to start this treatment.
Belo Horizonte, Minas GeraisAges Any age - NCT06241612RecruitingPhase 3
Personalized neck radiation for nasopharyngeal cancer
This trial tests whether giving radiation only to the specific lymph nodes that need it works as well as standard radiation for people with nasopharyngeal cancer. It aims to reduce side effects while still controlling the cancer.
Guangzhou, GuangdongAges 18–70 - NCT06383091Recruiting
Manual therapy for voice recovery after thyroid removal
This study tests if a special hands-on therapy (manual therapy) can help your voice and throat muscles recover better after total thyroidectomy. It may reduce voice problems that sometimes happen after surgery.
Baltimore, MarylandAges 18 years+
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,269 recruiting otolaryngology studies from the U.S. registry right now, out of 2,074 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.