Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,371 recruiting studies in this area right now.
By phase
- Not applicable978
- Phase 2168
- Phase 399
- Phase 146
- Phase 434
- Phase 1/Phase 232
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma80
- Dysphagia73
- Hearing Loss61
- Tinnitus31
- Hearing Loss, Sensorineural25
- Nasopharyngeal Carcinoma (NPC)24
- Allergic Rhinitis23
- Head and Neck Cancer22
- Oropharynx Cancer21
- Stroke20
- Sensorineural Hearing Loss18
- Nasopharyngeal Cancinoma (NPC)17
- Chronic Rhinosinusitis With Nasal Polyps15
- Oropharyngeal Cancer15
- Nasopharyngeal Cancer14
- Vestibular Schwannoma14
- Head and Neck Squamous Cell Carcinoma13
- Chronic Rhinosinusitis (CRS)12
Leading sponsors
- Sun Yat-sen University59
- Eye & ENT Hospital of Fudan University17
- Cairo University15
- Assistance Publique - Hôpitaux de Paris14
- NYU Langone Health14
- Mayo Clinic12
- National Cancer Institute (NCI)12
- Johns Hopkins University11
- Ming-Yuan Chen11
- Cochlear9
Where studies are running
- California62
- Maryland37
- New York35
- Florida30
- Massachusetts21
- Illinois20
- Texas18
- Arizona17
- Colorado16
- Alabama15
Recruiting studies1,371 total
- NCT06598319Recruiting
Pulsed field ablation for chronic rhinitis
This trial tests a new treatment that uses pulsed energy to target a nerve in the back of the nose to help with chronic rhinitis (long-term runny or stuffy nose). It is for people whose symptoms have not been controlled by nasal steroid sprays.
Colorado Springs, ColoradoAges 18–85 - NCT06599021Recruiting
Swallowing problems in older adults: a study
This study is looking at swallowing difficulties in people over 60. If you have trouble swallowing, you may be invited to try a simple exercise to help. The study first checks how common these problems are and how serious they are.
GothenburgAges 18 years+ - NCT07690670Recruiting
WhatsApp AI support vs paper support for new hearing aid users
This study tests whether using WhatsApp for support (with help from AI) is better than paper materials for people who are using hearing aids for the first time. It's for adults with mild to moderate hearing loss in both ears who can use WhatsApp.
Pretoria, ProvinceAges 18 years+ - NCT05730283RecruitingPhase 2
Preventing hearing damage from IV amikacin in NTM patients
This Phase 2 study looks at ways to prevent hearing damage (ototoxicity) in people with NTM lung infection who are treated with IV amikacin. If you qualify, the study may help protect your hearing while you receive a treatment that can sometimes affect hearing.
San Francisco, CaliforniaAges 18–80 - NCT06743490Recruiting
Tracking MG symptoms with smartphone recordings
This study uses your smartphone to record symptoms like slurred speech, hoarseness, arm fatigue, or droopy eyelids, making it easier for doctors to understand and monitor myasthenia gravis. Both people with MG and healthy volunteers can take part.
Leiden, South HollandAges 18 years+ - NCT06930781Recruiting
Study of Ponto implants outside of the operating room
This study looks at how well Ponto implants work when placed in a clinic or office setting instead of a hospital operating room. It is for adults who already had this procedure in 2019 or later.
Sacramento, CaliforniaAges 18 years+ - NCT06600919Recruiting
Music therapy app for anxiety before ENT surgery
This study tests whether listening to calming music through a phone app before ENT surgery can help prevent anxiety. It is for adults who are scheduled for ear, nose, or throat surgery.
Saint-DenisAges 18 years+ - NCT06604494Recruiting
Spotting fistulas early after throat cancer surgery
This study tests whether measuring a substance called a "cytokine" in fluid draining from the surgery site can help find a fistula (an abnormal opening) early after throat cancer surgery. If fistulas are found quickly, they can be repaired sooner, which may help you recover better.
Clermont-FerrandAges 18 years+ - NCT06611137RecruitingPhase 2
SBRT plus chemoimmunotherapy to save the voice box
This trial tests a new approach to treat advanced larynx or hypopharynx cancer without removing the voice box. First, you get targeted radiation (SBRT), then a combination of chemotherapy and an immunotherapy drug called Toripalimab, which helps your immune system fight the cancer.
Guangzhou, GuangdongAges 18–70 - NCT06611150RecruitingPhase 1
Chemo and radiation for advanced nasopharyngeal cancer
This trial tests whether a specific chemotherapy drug (nab-paclitaxel) given along with targeted radiation therapy can help people with stage III or IVa nasopharyngeal cancer. The goal is to improve treatment outcomes while managing side effects.
Guangzhou, GuangdongAges 18–70 - NCT06614686RecruitingPhase 1
CAR-T therapy for advanced head and neck cancer
This study tests a new type of CAR-T cell therapy that targets a protein called Trop2 found on some head and neck cancer cells. It's for people who have tried standard treatments and need a new option.
ShanghaiAges 18–70 - NCT06618742Recruiting
Cooling balloon for swallowing trouble in esophageal cancer
This study tests a cooling balloon device to treat trouble swallowing caused by advanced esophageal cancer. It aims to open up the esophagus so you can eat more easily.
UtrechtAges 18 years+ - NCT06623123RecruitingPhase 3
Phone app vs. talking therapy for tinnitus relief
This trial compares a smartphone app called Oto to standard talking therapies for treating tinnitus. If you have had tinnitus for at least 3 months and can use an app, this study may help you find relief.
Stevenage, HertfordshireAges 18 years+ - NCT06623799Recruiting
Allergic rhinitis, help-seeking, and mental health study
This study looks at how people with allergic rhinitis (hay fever) seek help and how that relates to their mental health. Researchers hope to learn more about the connection between allergies, anxiety, and depression over time.
West Palm Beach, FloridaAges 4–100 - NCT06625281Recruiting
Comparing two head exercises for dizziness from BPPV
This study tests if adding special head exercises (Brandt-Daroff) to two different repositioning maneuvers (Epley or Semont-Plus) helps reduce dizziness and improve quality of life in people with a common inner ear condition called BPPV.
IslamabadAges 20–65 - NCT06628414Recruiting
Brain stimulation study for tinnitus relief
This study tests whether a gentle brain stimulation technique called tDCS can help people with tinnitus. Volunteers will receive either real or fake stimulation to see if it reduces tinnitus symptoms.
NottinghamAges 18 years+ - NCT06629597RecruitingPhase 3
Study of YL201 for advanced nasopharyngeal cancer
This trial tests a new drug, YL201, in people with nasopharyngeal cancer that has come back or spread. It may be an option if you have already tried a PD-(L)1 inhibitor and at least two chemotherapy treatments.
Guangzhou, GuangdongAges 18–75 - NCT06630013Recruiting
Ultrasound test for swallowing problems in patients with a tracheostomy
This study tests if a new ultrasound score can help diagnose swallowing disorders in patients who are difficult to wean from a breathing tube and have a tracheostomy. It may help doctors better assess swallowing without more invasive tests.
Beuvry, BeuvryAges 18 years+ - NCT06635967Recruiting
TMS for chronic tinnitus
This study tests whether repeated magnetic pulses (TMS) can help people with ongoing tinnitus. If you have had tinnitus for at least 3 months and it bothers you enough to score 38 or more on the Tinnitus Handicap Inventory (THI), you may be eligible.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06636734RecruitingPhase 2
Lovastatin plus pembrolizumab for advanced head and neck cancer
This trial tests whether adding lovastatin (a cholesterol-lowering drug) to pembrolizumab (an immunotherapy) works better than pembrolizumab alone for head and neck cancer that has come back or spread. It's for people who haven't had immunotherapy before and aren't already on a statin.
Atlanta, GeorgiaAges 18 years+ - NCT06641999Recruiting
Tinnitus implant study for adults with chronic tinnitus and hearing loss
This trial tests if a special implant can reduce tinnitus loudness in adults who have had chronic tinnitus for at least 6 months and have some hearing loss. You may qualify if your tinnitus is severe and not helped by standard treatments like hearing aids or therapy.
Edegem, BelgiumAges 18 years+ - NCT06642324Recruiting
HPV and genetics in head and neck cancer study
This study looks at how HPV infection and genetic changes relate to head and neck squamous cell carcinoma. If you have this type of cancer, joining could help doctors learn more about the disease and improve future treatments.
Dhaka, Dhaka DivisionAges 18 years+ - NCT06643702Recruiting
Dizziness and balance in older adults
This study is looking at whether dizziness and balance problems in older adults are caused by BPPV (tiny crystals in the inner ear). If you qualify, you may be diagnosed with simple head movements.
Saltsjö-Boo, Stockholm CountyAges 65 years+ - NCT06651255Recruiting
Algorithm-guided care for bleeding in Von Willebrand disease
This trial tests whether a special algorithm can reduce repeat bleeding from the gut or nose in people with inherited Von Willebrand disease. If you have had serious nosebleeds or digestive bleeding, this study may help find a better way to manage your condition.
Lille, NordAges 18 years+
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,371 recruiting otolaryngology studies from the U.S. registry right now, out of 2,216 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.