Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,269 recruiting studies in this area right now.
By phase
- Not applicable890
- Phase 2154
- Phase 3103
- Phase 147
- Phase 431
- Phase 1/Phase 230
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma73
- Dysphagia66
- Hearing Loss61
- Tinnitus29
- Hearing Loss, Sensorineural24
- Nasopharyngeal Carcinoma (NPC)24
- Head and Neck Cancer23
- Allergic Rhinitis22
- Oropharynx Cancer21
- Nasopharyngeal Cancinoma (NPC)18
- Sensorineural Hearing Loss18
- Stroke17
- Oropharyngeal Cancer14
- Vestibular Schwannoma14
- Chronic Rhinosinusitis With Nasal Polyps13
- Deafness13
- Head and Neck Squamous Cell Carcinoma13
- Nasopharyngeal Cancer13
Leading sponsors
- Sun Yat-sen University57
- Assistance Publique - Hôpitaux de Paris14
- Eye & ENT Hospital of Fudan University14
- National Cancer Institute (NCI)14
- Cairo University13
- NYU Langone Health13
- Mayo Clinic12
- Johns Hopkins University11
- Ming-Yuan Chen11
- Massachusetts Eye and Ear Infirmary10
Where studies are running
- California61
- Maryland38
- Florida32
- New York32
- Massachusetts24
- Illinois20
- Texas20
- Alabama15
- Arizona15
- Colorado15
Recruiting studies1,269 total
- NCT06567821RecruitingPhase 2/Phase 3
Using navigation to improve balloon sinus surgery accuracy
This trial tests whether using a navigation system during balloon sinus surgery makes the procedure more accurate for people with chronic sinusitis. It may help improve outcomes for those who have not had sinus surgery before.
Los Angeles, CaliforniaAges 18 years+ - NCT06580847Recruiting
Choir for older adults with untreated hearing loss
This trial tests whether joining a choir helps older adults with untreated hearing loss. If you have mild-to-moderate hearing loss and do not use hearing aids, this study may be a good fit for you.
Los Angeles, CaliforniaAges 60 years+ - NCT05157685RecruitingPhase 3
Azithromycin for chronic pus-filled sinus inflammation
This Phase 3 trial tests whether the antibiotic azithromycin can improve chronic sinus problems where there is persistent pus and swelling. It’s for adults who have not improved despite at least two prior antibiotics.
BordeauxAges 18–70 - NCT06554158Recruiting
Lowering radiation for low-risk HPV throat cancer patients
This trial tests whether giving less radiation after surgery is safe and effective for people with early-stage HPV-related throat cancer. It aims to reduce side effects while still controlling the cancer.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06560255RecruitingPhase 3
Fish oil in pregnancy to prevent childhood asthma
This study tests if taking fish oil during pregnancy can help lower the risk of childhood asthma. If you have low omega-3 levels, you may be randomly assigned to receive fish oil or a placebo.
Gentofte MunicipalityAges 18–45 - NCT06563362RecruitingPhase 2
Personalized radiation for oropharyngeal cancer
This trial tests a personalized approach to radiation therapy for oropharyngeal cancer. The goal is to safely reduce the amount of radiation to healthy lymph nodes, which may lower side effects while still effectively treating the cancer.
Zurich, Canton of ZurichAges 18 years+ - NCT06034080Recruiting
Cutting down unneeded antibiotics for children's ear infections
This study tests ways to help doctors avoid prescribing antibiotics when they are not needed for children with ear infections. If you are a parent of a child diagnosed with an ear infection or a healthcare provider, you may be able to join different parts of the study.
Denver, ColoradoAges 6 months–17 years - NCT06547372Recruiting
Dietary changes for eczema relief
This study tests whether a specific diet can help manage mild to moderate eczema. It involves eating whole foods provided by the researchers for a set period and tracking your skin health.
Singapore, SingaporeAges 21–65 - NCT06532279RecruitingPhase 2
Testing BMX-001 with chemoradiation for head and neck cancer
This trial tests whether adding BMX-001 (a drug that may protect healthy tissues) to standard chemoradiation can reduce side effects and improve outcomes for people with head and neck cancer. It's a randomized study, so you would have a 50/50 chance of getting BMX-001 or a placebo.
Gilbert, ArizonaAges 18 years+ - NCT06543823Recruiting
New bandage for throat surgery pain relief
This trial tests a special wound dressing (SUPRATHEL 250) placed inside the throat after tonsil removal. It aims to see if it helps throat wounds heal faster with less pain.
Stuttgart, Baden-WurttembergAges 18 years+ - NCT06543316Recruiting
Treating gastric bypass ulcers with low-thermal argon plasma
This study tests a new way to treat painful sores (marginal ulcers) that can happen after gastric bypass surgery. Doctors use a special tool (argon plasma) during an endoscopy to help the sores heal faster, and you will get standard ulcer medicine too.
Boston, MassachusettsAges 18 years+ - NCT06537531Recruiting
Video study of breathing tube placement in Spain
This trial records videos of the breathing tube placement process during planned surgeries at hospitals in Spain and Portugal. The goal is to study different techniques and improve safety.
Madrid, MadridAges 18–90 - NCT06517355Recruiting
Onco-sexology program for laryngectomy patients and partners
This study tests an onco-sexology program designed to help patients who have had their voice box removed (laryngectomy) and their partners improve their intimate life and well-being after cancer treatment.
ToulouseAges 18 years+ - NCT06517446Recruiting
Virtual reality therapy for one-sided inner ear balance problems
This trial tests if virtual reality-based optokinetic stimulation can help people with balance problems caused by reduced function in one inner ear. It may offer a new way to retrain your balance system.
KocaeliAges 18–65 - NCT06520579Recruiting
Behavioral help before and after neck surgery
This trial tests if a simple behavioral program can help adults prepare for and recover from anterior neck surgery (ACDF). It includes extra support and nutrition tips to improve healing.
New York, New YorkAges 21–99 - NCT06516575Recruiting
Listening effort in cochlear implant users
This study measures how much effort it takes to listen and understand speech for adults with cochlear implants compared to those with normal hearing. It can help researchers learn how to improve hearing outcomes.
Minneapolis, MinnesotaAges 18–75 - NCT06517888RecruitingPhase 1/Phase 2
Gene therapy for hearing loss from vestibular schwannoma
This trial tests a gene therapy injected into the ear to slow tumor growth and prevent further hearing loss in people with a vestibular schwannoma that is getting worse. It's for those who already have severe hearing loss in the affected ear.
Baltimore, MarylandAges 18 years+ - NCT06512064Recruiting
Breath sound analysis for lung health
This study tests a new device that listens to your breathing to check how well your lungs are working. It might help diagnose lung conditions without the need for forceful blowing tests, making it easier for patients.
Indianapolis, IndianaAges 8–70 - NCT06507709Enrolling by invitation
Sinus lift study using a special bone graft putty
This study tests a new type of bone graft putty for people who need a sinus lift before getting dental implants. It may be an option if you have some existing bone and are generally healthy or have well-controlled diabetes.
San Antonio, TexasAges 18–85 - NCT06507007Recruiting
Inner ear function in Turner syndrome
This study looks at why some people with Turner syndrome have inner ear problems. It uses MRI and CBCT scans to understand the genetic and epigenetic causes.
HerningAges 18–60 - NCT06510972Recruiting
Eating versus fasting for ICU patients with breathing failure
This study looks at whether it's safe and helpful to let people with severe breathing problems in the ICU eat and drink normally instead of fasting. If you qualify, you may be assigned to either continue eating or to fast while doctors monitor your recovery.
BloisAges 18 years+ - NCT06501807Recruiting
Biologics for severe nasal polyps: a French registry study
This study follows patients in France who are receiving biologic treatments for severe nasal polyps with chronic sinusitis. It collects information on how well these treatments work and their side effects over time.
LilleAges 18 years+ - NCT06500975Recruiting
Long-Term Results After Vestibular Implant
This study checks how well a vestibular implant works over many years for people who already got one in earlier research at Johns Hopkins.
Baltimore, MarylandAges 22–90 - NCT06512662Recruiting
Support program for ENT cancer patients in a day hospital
This trial offers a support program for patients undergoing surgery for head and neck cancer. The goal is to help with recovery and well-being.
BrestAges 18 years+
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,269 recruiting otolaryngology studies from the U.S. registry right now, out of 2,074 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.