Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,366 recruiting studies in this area right now.
By phase
- Not applicable975
- Phase 2167
- Phase 398
- Phase 146
- Phase 434
- Phase 1/Phase 232
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma80
- Dysphagia72
- Hearing Loss61
- Tinnitus31
- Hearing Loss, Sensorineural25
- Allergic Rhinitis23
- Nasopharyngeal Carcinoma (NPC)23
- Head and Neck Cancer22
- Oropharynx Cancer21
- Stroke19
- Sensorineural Hearing Loss18
- Nasopharyngeal Cancinoma (NPC)16
- Chronic Rhinosinusitis With Nasal Polyps15
- Oropharyngeal Cancer15
- Nasopharyngeal Cancer14
- Vestibular Schwannoma14
- Head and Neck Squamous Cell Carcinoma13
- Chronic Rhinosinusitis (CRS)12
Leading sponsors
- Sun Yat-sen University58
- Eye & ENT Hospital of Fudan University17
- Cairo University15
- Assistance Publique - Hôpitaux de Paris14
- NYU Langone Health14
- Mayo Clinic12
- National Cancer Institute (NCI)12
- Johns Hopkins University11
- Ming-Yuan Chen10
- Cochlear9
Where studies are running
- California62
- Maryland37
- New York35
- Florida29
- Massachusetts21
- Illinois20
- Arizona17
- Texas17
- Colorado16
- Alabama15
Recruiting studies1,366 total
- NCT06676592Recruiting
3D technology to guide head and neck surgery
This trial tests whether 3D imaging can help surgeons better plan and perform head and neck operations. If you're scheduled for head and neck surgery and standard scans, this study may improve your surgical precision.
Basking Ridge, New JerseyAges 18 years+ - NCT06669611RecruitingPhase 3
Comparing two drug combos for advanced nasopharyngeal cancer
This trial tests whether a new drug combination (Nab-Paclitaxel with Camrelizumab) works better than the standard GP chemotherapy plus Camrelizumab for people whose nasopharyngeal cancer has come back or spread. The goal is to find a more effective treatment option.
Guangzhou, GuangdongAges 18 years+ - NCT06661967Recruiting
Numbing gel for breathing tube insertion in emergencies
This trial tests if adding a numbing gel to standard care helps doctors insert a breathing tube more quickly on the first try. If you need a breathing tube in the emergency room and are over 18, you may be able to join.
Chon Buri, Changwat Chon BuriAges 18 years+ - NCT06530264Recruiting
Comparing methods for tear duct surgery
This trial compares different ways to manage the flap during external dacryocystorhinostomy (a surgery to clear blocked tear ducts). It may help if you have a blocked tear duct, a tear sac infection or a tear sac cyst or fistula.
MinyaAges 18–75 - NCT06517355Recruiting
Onco-sexology program for laryngectomy patients and partners
This study tests an onco-sexology program designed to help patients who have had their voice box removed (laryngectomy) and their partners improve their intimate life and well-being after cancer treatment.
ToulouseAges 18 years+ - NCT06572514RecruitingPhase 1/Phase 2
Lower radiation after chemo-immunotherapy for head and neck cancer
This trial tests if giving less radiation than usual is safe and effective for certain head and neck cancers after initial treatment with chemotherapy and immunotherapy. It aims to reduce side effects while still controlling the cancer.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06533436Recruiting
Comparing two ways to secure a breathing tube
This study compares two methods of holding a breathing tube in place for patients who are already intubated. The goal is to see which method works better and costs less.
SuresnesAges 18 years+ - NCT06470217RecruitingPhase 2
Study of tirilizumab plus chemo for advanced oral cancer
This trial tests a combination of immunotherapy (tirilizumab) and two chemotherapy drugs (albumin-bound paclitaxel and cisplatin) for people with advanced but removable oral cancer. The goal is to see if this treatment shrinks the tumor before surgery and improves outcomes.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06447818Recruiting
Airway changes after sleep apnea surgery
This study looks at how surgery for obstructive sleep apnea (a condition where breathing stops and starts during sleep) may affect your airway. The goal is to understand if the surgery makes it easier to manage your airway in the future.
Kocaeli, IzmıtAges 18–65 - NCT06283095Recruiting
Expanding the palate to help sleep apnea
This surgery expands the palate to treat obstructive sleep apnea caused by a narrow upper airway. It may help people with mild to moderate sleep apnea who have a specific type of airway collapse seen on a sleep-endoscopy test.
AsyutAges 18–70 - NCT06264245Recruiting
Sound processing at work and hearing health study
This trial looks at how using platforms that change sound, like online meeting tools, might affect your hearing. It compares people who use these tools a lot with those who use them less.
BrusselsAges 18 years+ - NCT06282601Recruiting
Music and language study for older adults with hearing loss
This study tests whether listening to rhythmic or non-rhythmic music can help improve sentence understanding in older adults with age-related hearing loss. It aims to see if music patterns can boost language skills.
DijonAges 70 years+ - NCT06165536Recruiting
Using voice strategies to reduce vocal fold pressure
This study tests different ways of using your voice to reduce pressure on vocal fold lesions caused by overuse. If you are between 18 and 40, have been diagnosed with such lesions, and are going to voice therapy, you may be able to join.
Los Angeles, CaliforniaAges 18–40 - NCT05925491RecruitingPhase 2
Pembrolizumab for locally advanced nasal cavity cancer
This trial tests pembrolizumab (an immune therapy) for locally advanced sinonasal cancer that can still be cured with local treatments. It aims to improve outcomes by helping your immune system better fight the tumor.
Pavia, LombardyAges 18 years+ - NCT05967507Recruiting
Testing oxygen flow during infant airway tube placement
This trial studies how different oxygen flow rates affect breathing during the process of placing a breathing tube in babies. It may help clinicians choose safer oxygen settings during routine and urgent (but not life-threatening) airway management.
Philadelphia, PennsylvaniaAges Up to 12 months - NCT06033144Recruiting
Tapia's syndrome study in breathing recovery unit
This study looks at how common Tapia's syndrome (a rare nerve problem after breathing tube use) is in patients recovering from long-term breathing support. If you've had a breathing tube for more than 48 hours, you may be able to help researchers learn more about this condition.
Férolles-Attilly, Seine-et-MarneAges 18 years+ - NCT05940441Recruiting
Low-dose capecitabine after throat cancer treatment
This study tests whether low-dose capecitabine given after standard treatment can lower the chance that locoregional (nearby) throat cancer returns. It is designed for adults with advanced hypopharyngeal (throat) cancer who have finished curative chemoradiation or surgery and follow-up therapy and show no active cancer on exam.
ShanghaiAges 18–65 - NCT06051006Recruiting
Testing Cochlear Implant Settings in Teens
This study tests a method to set cochlear implant sound levels using a small reflex in the ear. It may help doctors find the best sound settings for users aged 8-17.
ParisAges 8–17 - NCT05922085Recruiting
Ultrasound check to spot swallowing trouble after ICU care
This trial tests whether bedside ultrasound can help identify people at risk for swallowing problems that can start after time in the ICU and on a breathing machine. If you’re at risk early, the goal is to guide the care team to take steps sooner to prevent complications.
DijonAges 18 years+ - NCT06047665Recruiting
Outcomes after tracheal tube removal
This study looks at how patients do after their tracheostomy tube is removed. It aims to understand the process and results for people who have had the tube taken out at the Swiss Paraplegic Center.
Nottwil, Canton of LucerneAges 18 years+ - NCT05917496Recruiting
Support study for families after early cochlear implants
This study looks at how parent support helps children who get cochlear implants very early, and how well their language develops. You may be able to join if your child meets the timing and hearing/implant requirements and you speak French at home.
ParisAges 11 months–1.8 years - NCT05652192RecruitingPhase 2
SBRT radiation plus chemotherapy and immunotherapy for metastatic nasopharyngeal cancer
This trial tests whether adding targeted radiation (SBRT) to chemotherapy and an immunotherapy drug can help people with metastatic nasopharyngeal cancer live longer and control tumors. It may help by combining local tumor treatment with whole-body immune support.
Hangzhou, ZhejiangAges 18–75 - NCT05774717RecruitingPhase 1
Tranexamic acid for bleeding after open nose surgery
This Phase 1 study tests whether tranexamic acid (a medicine that helps reduce bleeding) can lessen bleeding, swelling, and bruising after open rhinoplasty. You may be asked to take it around the time of surgery if you meet safety and lab criteria.
Nashville, TennesseeAges 18 years+ - NCT05710679Recruiting
Blood test predicts leftover cancer after intensified head and neck radiation
This study uses a blood test to see whether cancer DNA is still detectable after a stronger combination of radiation and chemotherapy for locally advanced head and neck cancer. The goal is to predict who may have “residual” (remaining) disease and help guide future care.
Clermont-Ferrand, Puy-de-DômeAges 18–80
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,366 recruiting otolaryngology studies from the U.S. registry right now, out of 2,207 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.