Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,269 recruiting studies in this area right now.
By phase
- Not applicable890
- Phase 2154
- Phase 3103
- Phase 147
- Phase 431
- Phase 1/Phase 230
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma73
- Dysphagia66
- Hearing Loss61
- Tinnitus29
- Hearing Loss, Sensorineural24
- Nasopharyngeal Carcinoma (NPC)24
- Head and Neck Cancer23
- Allergic Rhinitis22
- Oropharynx Cancer21
- Nasopharyngeal Cancinoma (NPC)18
- Sensorineural Hearing Loss18
- Stroke17
- Oropharyngeal Cancer14
- Vestibular Schwannoma14
- Chronic Rhinosinusitis With Nasal Polyps13
- Deafness13
- Head and Neck Squamous Cell Carcinoma13
- Nasopharyngeal Cancer13
Leading sponsors
- Sun Yat-sen University57
- Assistance Publique - Hôpitaux de Paris14
- Eye & ENT Hospital of Fudan University14
- National Cancer Institute (NCI)14
- Cairo University13
- NYU Langone Health13
- Mayo Clinic12
- Johns Hopkins University11
- Ming-Yuan Chen11
- Massachusetts Eye and Ear Infirmary10
Where studies are running
- California61
- Maryland38
- Florida32
- New York32
- Massachusetts24
- Illinois20
- Texas20
- Alabama15
- Arizona15
- Colorado15
Recruiting studies1,269 total
- NCT06535087Recruiting
How airway allergies affect children and parents' quality of life
This study looks at how airway allergies (like asthma and hay fever) affect the daily life of children and their parents. By filling out a questionnaire, you can help researchers understand these challenges and find better ways to support families.
Shanghai, Shanghai MunicipalityAges 5–16 - NCT07791095RecruitingPhase 4
Improved accuracy for naso-orbito-ethmoidal fracture repair
This trial tests whether using a 3D virtual model to plan surgery and pre-bend plates helps surgeons repair fractures around the nose, eye socket, and forehead more accurately. This may lead to better facial alignment and recovery.
AlexandriaAges 18 years+ - NCT07789665Recruiting
Auditory nerve implant for deaf adults who cannot use cochlear implants
This study is testing a new way to use an inner ear implant (called an auditory nerve implant, or ANI) to help people who are deaf in both ears and cannot use a cochlear implant. The researchers want to see how well people perceive sounds with this device.
HanoverAges 18–85 - NCT07788638Recruiting
Neurofeedback training for tinnitus relief
This study tests a non-invasive brain training method called neurofeedback to help reduce the distress caused by tinnitus, which is a constant ringing or buzzing in the ears. If you have bothersome tinnitus, this treatment might help you feel better.
Urbana, IllinoisAges 18–70 - NCT07790679Recruiting
Microbial testing for severe outer ear infections
This study is looking at people with a severe outer ear infection called malignant otitis externa, which often affects those with diabetes or weakened immune systems. The goal is to test for bacteria or fungi in the infection to guide better treatment.
Sohag, Sohag GovernorateAges Any age - NCT07787312Recruiting
Ultrasound for swallowing and muscle loss in intensive care patients
This study uses ultrasound to check the muscles that help you swallow and move. It aims to see if measuring these muscles can predict swallowing problems and muscle loss after being on a breathing machine.
Madrid, MadridAges 18 years+ - NCT05933889Recruiting
Study of robotic throat surgery for early oropharyngeal cancer
This study looks at how well different robotic surgery approaches work for people with early oropharyngeal squamous cell carcinoma (throat cancer). You may be asked for consent for extra tissue and imaging analysis to help researchers understand patterns related to outcomes.
LondonAges 18 years+ - NCT05892354Recruiting
Immunonutrition to reduce mouth sores after cancer treatment
This trial studies whether special nutritional supplements (immunonutrients) can reduce painful mouth sores (oral mucositis) in people with nasopharyngeal cancer after chemoradiotherapy. If you qualify, you’ll be followed with visits and lab tests to see if the supplements improve comfort and recovery.
Fuzhou, FujianAges 18–70 - NCT07782957RecruitingPhase 3
New shot for severe nasal polyps with ongoing sinus symptoms
This study tests an experimental medication called felcorekibart, given as an injection, to see if it reduces nasal polyps and improves sinus symptoms like congestion and loss of smell. It is for adults who have had nasal polyps for at least a year and have already tried standard treatments like steroid sprays or pills, or had surgery.
Sherman Oaks, CaliforniaAges 18 years+ - NCT07782970RecruitingPhase 3
Treatment for chronic sinusitis with nasal polyps
This study tests a new medication (felcorekibart) to see if it reduces nasal polyps and symptoms like congestion and loss of smell. It may help people whose current treatments aren't enough.
Los Angeles, CaliforniaAges 18 years+ - NCT07781085Recruiting
Radiation therapy after surgery for early glottic cancer
This study looks at whether adding radiation therapy after surgery improves outcomes for people with early-stage glottic cancer that involves the anterior commissure (the front part of the vocal cords). If you join, you may receive radiation therapy or not, and the researchers will compare the results.
Hangzhou, ZhejiangAges 18 years+ - NCT07781098Recruiting
Radiation therapy for early-stage voice box cancer with poor differentiation
This trial studies whether adding radiation therapy after surgery can help people with early-stage voice box cancer that has poor differentiation (cells look very abnormal). It aims to improve outcomes for this specific type of cancer.
Hangzhou, ZhejiangAges 18 years+ - NCT07781072RecruitingPhase 2
Immunotherapy plus radiation for advanced head and neck cancer
This trial tests a combination of an immunotherapy drug (sintilimab) with radiation and chemotherapy for people with advanced head and neck cancer. The goal is to see if this approach can shrink tumors and improve outcomes.
Hangzhou, ZhejiangAges 18–75 - NCT07780981Recruiting
Body position study for endoscopy pressure measurements
This study looks at whether lying on your back or side affects a measurement taken during a routine endoscopy procedure to check how well your esophagus and stomach opening are working. It may help doctors get more accurate readings to guide your care.
Baltimore, MarylandAges 5–21 - NCT07780760Recruiting
Numbing throat spray to ease pain after tonsil removal in children
This study tests whether a numbing mist sprayed into the throat before surgery can reduce sore throat pain children feel after having their tonsils removed. It compares two numbing medicines to see if one works better than the other.
Al FayyumAges 3–15 - NCT07781358RecruitingPhase 2
Testing a new drug combination for recurrent nasopharyngeal cancer
This trial tests a new drug combination for people whose nasopharyngeal cancer has come back in the same area or nearby lymph nodes. The goal is to see if this treatment can shrink or control the cancer.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT07768189RecruitingPhase 3
Testing CRB-701 for throat cancer that returned
This study tests an investigational drug called CRB-701 to see if it can help people with a certain type of throat cancer that has not responded to standard treatments. The trial compares CRB-701 to a doctor's choice of other available treatments.
Huntsville, AlabamaAges 18 years+ - NCT07772973Enrolling by invitation
Two rotating chairs for diagnosing vertigo
This study compares two rotating chairs used to diagnose benign paroxysmal positional vertigo (BPPV), a common cause of dizziness. If you have typical vertigo symptoms, this trial may help find the best way to diagnose your condition.
Aalborg, North JutlandAges 18 years+ - NCT06572475Recruiting
New MRI contrast for brain tumors
This trial uses a new type of MRI contrast dye (USPIO) to get clearer images of certain slow-growing brain tumors (vestibular schwannomas and low-grade gliomas). The goal is to see if this dye helps doctors better understand and treat these tumors.
Salford, Greater ManchesterAges 16–100 - NCT06572514RecruitingPhase 1/Phase 2
Lower radiation after chemo-immunotherapy for head and neck cancer
This trial tests if giving less radiation than usual is safe and effective for certain head and neck cancers after initial treatment with chemotherapy and immunotherapy. It aims to reduce side effects while still controlling the cancer.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07762976RecruitingPhase 2
Tailoring chemo for nasopharyngeal cancer using EBV-DNA and MRI
This trial tests whether adjusting chemotherapy based on tumor markers (EBV-DNA) and MRI scans can improve outcomes and reduce side effects for people with nasopharyngeal cancer. If you have stage II or III disease, this study might help guide your treatment more precisely.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT07765186Recruiting
How sound and attention affect hearing with cochlear implants
This study tests how people focus on sounds in noisy situations, comparing those with normal hearing and those with cochlear implants. It aims to better understand how the brain processes sound, which could improve hearing technology.
Tampa, FloridaAges 18–90 - NCT05517135Recruiting
Personalized treatment for EBV-positive nasopharyngeal cancer
This trial tests a “choose the best treatment” approach for people with nasopharyngeal cancer (NPC) that is linked to EBV (a common virus). By matching treatment to your EBV and cancer features, the study aims to improve outcomes while tracking safety.
SingaporeAges 21–99 - NCT03996824Recruiting
Gene therapy study for certain vestibular schwannoma surgeries
This trial tests delivering gene therapy into the inner-ear hearing balance nerve cells during surgery for vestibular schwannoma. It may help by improving how the inner ear functions after tumor removal, but you must meet several specific surgery and safety requirements.
Le Kremlin-Bicêtre, Île-de-France RegionAges 18 years+
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,269 recruiting otolaryngology studies from the U.S. registry right now, out of 2,074 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.