Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,607 recruiting studies in this area right now.
By phase
- Not applicable5,335
- Phase 2607
- Phase 1557
- Phase 3417
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 385
Top conditions
- Obesity619
- Ovarian Cancer336
- Pancreatic Cancer289
- Type 2 Diabetes276
- Diabetes192
- Diabetes Mellitus183
- Diabetes Mellitus, Type 2170
- Hypertension138
- Type 1 Diabetes130
- Metabolic Syndrome126
- Obesity & Overweight123
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Colorectal Cancer92
- Pancreas Cancer90
- Endometrial Cancer87
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center41
- Massachusetts General Hospital41
- Eli Lilly and Company40
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland180
- Alabama176
- Arizona170
- Florida166
- Texas158
- Massachusetts151
- New York142
- Colorado115
- Pennsylvania113
Recruiting studies7,607 total
- NCT07743164RecruitingPhase 3
Raludotatug deruxtecan for PARP-inhibitor-resistant ovarian cancer
This trial tests a new drug called raludotatug deruxtecan (with or without bevacizumab) for people with ovarian cancer that has grown despite PARP inhibitor maintenance treatment. The goal is to see if this drug can shrink tumors or slow the cancer's growth.
Fountain Valley, CaliforniaAges 18 years+ - NCT03481829Recruiting
Long-term study tracking health factors from pregnancy
This study follows pregnant mothers and their babies for years to understand how early life factors can affect health later. If you qualify, you and your child(ren) will be asked to stay in the research study for at least 3 years after delivery.
Phoenix, ArizonaAges 1 day–99 years - NCT07798284RecruitingPhase 1
Weight loss capsule for obesity
This study tests an experimental capsule that may help with weight loss. It is for people who are overweight or obese and have not been able to lose weight with lifestyle changes alone.
Beijing, Beijing MunicipalityAges 18–65 - NCT00029965Recruiting
Natural history of inherited metabolic storage disorders
This study follows people with certain inherited metabolic conditions (like GM1 or GM2 gangliosidosis, sialidosis, or galactosialidosis) to learn more about how these diseases progress over time. Participating may help researchers understand the conditions better, which could improve future care.
Bethesda, MarylandAges 1 day–100 years - NCT07061574RecruitingPhase 1/Phase 2
Immune treatment for new onset type 1 diabetes
This study tests a low dose of a drug that calms the immune system, followed by either another immune drug or a blood pressure medicine, to see if they can help preserve the body's ability to make insulin in people recently diagnosed with type 1 diabetes. It may help keep your own insulin production going longer.
Los Angeles, CaliforniaAges 9–20 - NCT06586957RecruitingPhase 1
Study of NKT3964 for advanced solid tumors
This trial tests an experimental drug called NKT3964 for people with certain advanced cancers that have stopped responding to standard treatments. It aims to see if the drug can shrink tumors or slow their growth.
Little Rock, ArkansasAges 19 years+ - NCT06274749Recruiting
Urolithin A for blood sugar in adults 55+ with extra weight
This study tests if a natural supplement called Urolithin A can help improve how your body handles sugar (glucose) in healthy adults aged 55 and older who have a higher body weight. You would take a daily capsule and come in for tests including blood work, treadmill walks, and an MRI.
Baltimore, MarylandAges 55–100 - NCT07159841RecruitingPhase 2/Phase 3
Study of a new drug for children with classic CAH
This study tests a new medication for children with classic congenital adrenal hyperplasia (CAH). It aims to see if the drug helps better control hormone levels and reduce the need for high doses of current steroid medicines.
San Francisco, CaliforniaAges 1–17 - NCT07807956RecruitingPhase 1
Intravenous study drug for advanced solid tumors
This trial tests an investigational drug given through an IV to see if it can help people with advanced solid tumors. It aims to learn about side effects, how the drug works in the body, and whether it can slow or shrink the cancer.
Grand Rapids, MichiganAges 18 years+ - NCT07843238Recruiting
Virtual care for older adults with long-term conditions
This study will test a new virtual care program for people over 60 with conditions like high blood pressure, diabetes, or high cholesterol. It uses a phone, tablet, or computer to connect with healthcare providers, which might make it easier to manage your health from home.
Kuala LumpurAges 60 years+ - NCT07683065Recruiting
Secukinumab treatment in psoriasis patients with liver condition
This study looks at how well secukinumab works for psoriasis patients who also have a type of fatty liver disease called MASLD. It may help doctors understand if this treatment is a good option for people with both conditions.
Badalona, BarcelonaAges 18–100 - NCT07144163RecruitingPhase 3
Atumelnant for adults with classic CAH
This study tests a new drug, atumelnant, for adults with classic congenital adrenal hyperplasia (CAH) caused by 21-OHD. It aims to see if it can help control hormone levels while allowing lower doses of current steroid medications.
Los Angeles, CaliforniaAges 18–74 - NCT06184373Recruiting
Early glucose monitoring after gestational diabetes pilot
This study tests a continuous glucose monitor (a small patch that tracks your blood sugar) for a few weeks after you give birth. It aims to see if this tool can help women who recently had gestational diabetes better understand their blood sugar levels after delivery.
Columbus, OhioAges 18–50 - NCT07570316RecruitingPhase 3
Testing efgartigimod for Graves' disease hyperthyroidism
This study tests whether efgartigimod, an injectable medication given under the skin, can help control overactive thyroid (Graves' disease) in adults already taking methimazole or carbimazole. The goal is to see if it reduces thyroid antibodies and improves thyroid hormone levels.
Orange, CaliforniaAges 18 years+ - NCT07556679Enrolling by invitation
Play2Control: Reducing screen time for teens with type 2 diabetes
This study tests whether helping families spend less time watching TV or using screens can improve blood sugar control in children and teens with type 2 diabetes. It may help you manage diabetes better by cutting down on screen time.
Miami, FloridaAges 5–21 - NCT00027274Recruiting
Cancer risk in inherited bone marrow failure syndromes
This study looks at why people with inherited bone marrow failure syndromes (rare genetic conditions affecting blood cell production) have higher cancer risk. Researchers want to understand the genetic and medical factors that increase cancer likelihood, which could help doctors monitor and protect affected patients and their families.
Bethesda, MarylandAges 1 day–100 years - NCT07596849RecruitingPhase 3
Testing a New Injection for Graves' Disease
This study tests efgartigimod, a new medicine given by injection under the skin, to see if it can help control Graves' disease (an overactive thyroid condition). The goal is to reduce the need for other thyroid medications or help people stop taking them.
Aalst, Oost-VlassAges 18 years+ - NCT07676565Recruiting
Adding new drugs to insulin for type 1 diabetes
This study tests whether adding certain diabetes pills (GLP-1 receptor agonists or SGLT inhibitors) to insulin is safe and helpful for adults with type 1 diabetes. Doctors will check your glucose monitor data to see how well this works.
Newport Beach, CaliforniaAges 18 years+ - NCT04743271Recruiting
Test how food timing affects the body’s daily rhythms
This study looks at how the timing of meals (and daily timing habits) affects your body’s natural clock and related health measures. It involves healthy, generally low-risk participants and may help researchers understand how timing affects metabolism and sleep.
Portland, OregonAges 18–40 - NCT06273072RecruitingPhase 2
Metformin for asthma in overweight adults
This trial tests whether the diabetes drug metformin can help people with asthma who are also overweight or obese. The goal is to see if it improves asthma control and reduces the need for rescue medications.
Baltimore, MarylandAges 18 years+ - NCT07831343Recruiting
Malnutrition in young infants under 6 months study
This study follows infants younger than 6 months who are in the hospital due to acute malnutrition. It aims to better understand their condition and improve care.
Semarang, Central JavaAges 1 day–6 months - NCT07562152RecruitingPhase 3
Atebimetinib Plus Gemcitabine/Nab-Paclitaxel for New Pancreatic Cancer
This trial tests a combination of three drugs—atebimetinib (a new targeted therapy), gemcitabine, and nab-paclitaxel (two standard chemotherapy drugs)—as a first treatment for pancreatic cancer that has spread beyond the pancreas. The goal is to see if adding atebimetinib helps patients live longer and feel better.
Huntsville, AlabamaAges 18 years+ - NCT07848191RecruitingPhase 4
Liver drug combination study for MASH and liver scarring
This study tests whether taking rezdiffra (a liver medication) together with other common diabetes or liver drugs is safe and effective for adults with MASH (fatty liver disease) and moderate-to-severe liver scarring. It may help improve liver health and reduce disease progression.
Chandler, ArizonaAges 18 years+ - NCT03197363Enrolling by invitation
Long-term study of adults living in Białystok
This study follows adults living in Białystok over time to learn about health and life patterns. If you’re invited to take part and agree, it may help researchers better understand community health.
BialystokAges 20–80
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,607 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,814 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.