Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,627 recruiting studies in this area right now.
By phase
- Not applicable5,353
- Phase 2607
- Phase 1557
- Phase 3419
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 385
Top conditions
- Obesity618
- Ovarian Cancer337
- Pancreatic Cancer287
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes131
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Cardiovascular Diseases105
- Overweight105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland179
- Alabama176
- Arizona170
- Florida166
- Texas158
- Massachusetts151
- New York144
- Colorado115
- Pennsylvania114
Recruiting studies7,627 total
- NCT07089940RecruitingEarly Phase 1
OMO-103 for advanced pancreatic cancer
This trial tests a new drug called OMO-103 in people with advanced pancreatic cancer that has spread or cannot be removed by surgery. It may be an option whether you have had treatment before or not, as long as it's been at least 2 weeks since your last therapy.
Portland, OregonAges 18 years+ - NCT06973408Recruiting
Diet and lifestyle study for weight management
This study tests whether a specific diet and behavior program can help people with overweight improve their health. You will be asked to follow a specific eating plan and eat certain foods provided by the researchers.
GothenburgAges 18–70 - NCT05501080Recruiting
Testing a hormone treatment to improve heart changes in PA
This trial tests whether a treatment called SAAE can improve “ventricular remodeling,” meaning changes in the heart muscle, in people with primary aldosteronism (PA). It may help the heart work more efficiently by targeting the cause of high aldosterone levels.
NanchangAges 18–60 - NCT05873842Recruiting
Compare shockwave balloon versus standard balloon for TAVI access
This trial tests whether a shockwave balloon placed through the femoral (groin) artery works better than the standard balloon approach during TAVI in people with difficult, heavily calcified leg/artery access. It may help improve the success and safety of getting instruments through the groin when arteries are “stiff and narrowed.”
AnconaAges 18 years+ - NCT06129968Recruiting
Improving ovarian cancer diagnosis in primary care
This trial is looking at how doctors can better use the CA125 blood test to find ovarian cancer earlier. If you are being tested for ovarian cancer in primary care, this study might help improve how future patients are diagnosed.
BirminghamAges Any age - NCT06152588Recruiting
Time-restricted eating for type 2 diabetes
This trial tests if eating only during a restricted time window each day can help control blood sugar in people with type 2 diabetes. If you have type 2 diabetes, are overweight, and usually eat over a long period each day, you may be able to join.
Herlev, DenmarkAges 18 years+ - NCT06184503Recruiting
How velmanase alfa works in children under 3 with alpha-mannosidosis
This study looks at how the drug velmanase alfa (Lamzede) works in the body of young children with alpha-mannosidosis. It's for children who started the drug before age 3.
Miami, FloridaAges Up to 3 years - NCT06897241Recruiting
How different starches affect your metabolism
This study tests how your body responds to different types of starch (quick, slow, and resistant). You will follow special diet plans and use monitoring devices to understand your personal metabolic reactions.
Gothenburg, Västra Götaland CountyAges 30–75 - NCT06976164Recruiting
Reflexology for Gestational Diabetes
This study tests whether reflexology (a gentle foot massage therapy) can help manage blood sugar in pregnant women with gestational diabetes. It is for women who are in the middle to late stages of pregnancy and are otherwise healthy.
CairoAges 20–35 - NCT06968442Recruiting
Obesity and severe COVID-19 study
This study looks at how obesity affects the body's response to severe COVID-19. It compares people with obesity to healthy-weight healthcare workers to understand differences in the immune system.
Rotterdam, South HollandAges 18–65 - NCT07085559RecruitingEarly Phase 1
Metabolically armed BCMA CAR-T for relapsed plasma cell cancer
This trial tests a new type of CAR-T cell therapy (Meta10-BCMA) that is "metabolically armed" to better fight cancer cells. It's for people with plasma cell cancers that have come back or not responded to multiple prior treatments, and whose cancer cells carry the BCMA protein.
Hefei, AnhuiAges 19–75 - NCT07075939Recruiting
Centralized care for ovarian cancer: a study of outcomes
This study looks at whether having ovarian cancer care coordinated by a special team (Multidisciplinary Tumor Board) leads to better outcomes. It reviews records of patients treated between 2018 and 2023 to understand how centralization affects their health.
Carpi, ModenaAges 18–99 - NCT07079228RecruitingPhase 3
Comparing a new drug with chemo for pancreatic cancer
This trial tests a new treatment called QLS31905 plus chemotherapy against a placebo plus chemotherapy for people with advanced pancreatic cancer that hasn't been treated yet. It aims to see if the new combination works better.
BeijingAges 18–75 - NCT07083401RecruitingPhase 1
Study of a New Drug Combination in Healthy Adults
This trial tests how a new combination of drugs (BR3006A, BR3006B, and BR3006C) is absorbed and processed by the body when taken together, compared to a single tablet (BR3006). It is for healthy adults to understand the safety and behavior of the medication.
Seoul, Gwanak-guAges 19 years+ - NCT07080385RecruitingPhase 2/Phase 3
Study of encaleret in children with a rare calcium disorder
This trial tests a medicine called encaleret in children with a rare genetic condition that causes low calcium levels. The goal is to see if it safely helps control calcium and reduce symptoms.
New Haven, ConnecticutAges birth–17 years - NCT07083388RecruitingPhase 1
Study of how different forms of BR3006 work in healthy adults
This trial tests how the body processes different forms of a drug called BR3006 in healthy volunteers. It compares a single tablet (BR3006) to a combination of three separate components (BR3006A, BR3006B, and BR3006C) given together. This helps researchers understand if the combination works the same as the single tablet.
Seoul, Gwanak-guAges 19 years+ - NCT07082192RecruitingPhase 2/Phase 3
Testing CB03-154 for adults with ALS
This trial tests a new medicine, CB03-154, to see if it can help people with ALS. Researchers are comparing different doses to find the safest and most effective one.
Beijing, Beijing MunicipalityAges 18–65 - NCT07082114RecruitingPhase 3
Testing a new tablet for type 2 diabetes
This study tests a new pill called HDM1002 for adults with type 2 diabetes. It aims to see if it helps control blood sugar when added to your current metformin treatment.
Yueyang, HunanAges 18–75 - NCT07083206Recruiting
Pitavastatin/ezetimibe for high cholesterol
This trial tests a combination pill of two cholesterol-lowering medicines (pitavastatin and ezetimibe) in adults who have been taking either atorvastatin or rosuvastatin for at least 3 months. It aims to see if switching to this new combination is safe and effective.
Yongin-siAges 19 years+ - NCT07082725RecruitingPhase 3
Study of oral nizubaglustat for Niemann-Pick type C
This study tests an oral medication called nizubaglustat for people with Niemann-Pick type C disease who cannot take or are not satisfied with the current treatment miglustat. It aims to see if the drug can help with symptoms like coordination and movement problems.
Oakland, CaliforniaAges 4 years+ - NCT07081646RecruitingPhase 1/Phase 2
CAR T cell therapy for AL amyloidosis
This trial tests a CAR T cell therapy that targets two proteins (CD19 and BCMA) on the surface of abnormal plasma cells. It is for people with AL amyloidosis whose disease has come back or did not respond to at least one prior treatment.
Phoenix, ArizonaAges 18 years+ - NCT07083336Recruiting
Diet study for type 2 diabetes with fatty liver disease
This trial tests a specific medical nutrition therapy diet to see if it can reduce liver fat and improve blood sugar control in people with type 2 diabetes and nonalcoholic fatty liver disease. It may help you manage both conditions with a dietary approach.
Yichang, HubeiAges 18 years+ - NCT07085572RecruitingPhase 2
Cemiplimab for maintenance in adrenocortical cancer
This trial tests a drug called cemiplimab as a maintenance treatment for patients with adrenocortical cancer whose disease did not worsen after initial chemotherapy. It is designed to keep the cancer from coming back.
Brescia, BresciaAges 18 years+ - NCT07079189Recruiting
Digital lifestyle tool for type 2 diabetes
This trial tests a digital lifestyle tool combined with a smart chatbot to help people with type 2 diabetes improve their blood sugar control. It's a home-based program that gives personalized advice and support.
Malmö, Skåne CountyAges 35 years+
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,627 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,981 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.