Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,607 recruiting studies in this area right now.
By phase
- Not applicable5,335
- Phase 2607
- Phase 1557
- Phase 3417
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 385
Top conditions
- Obesity619
- Ovarian Cancer336
- Pancreatic Cancer289
- Type 2 Diabetes276
- Diabetes192
- Diabetes Mellitus183
- Diabetes Mellitus, Type 2170
- Hypertension138
- Type 1 Diabetes130
- Metabolic Syndrome126
- Obesity & Overweight123
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Colorectal Cancer92
- Pancreas Cancer90
- Endometrial Cancer87
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center41
- Massachusetts General Hospital41
- Eli Lilly and Company40
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland180
- Alabama176
- Arizona170
- Florida166
- Texas158
- Massachusetts151
- New York142
- Colorado115
- Pennsylvania113
Recruiting studies7,607 total
- NCT07872683Recruiting
Drinking carbohydrates before hip or leg surgery: maltodextrin vs sugar water
This study compares two drinks given before surgery—maltodextrin (a carbohydrate powder mixed with water) versus sugar water—to see which one keeps the stomach empty and reduces risks during surgery on the lower limbs. It may help older patients have a safer and more comfortable experience.
Denpasar, BaliAges 60 years+ - NCT07864168Recruiting
Long-lasting glucose sensor study for type 1 and type 2 diabetes
This study tests a new extended-wear sensor that helps track glucose levels continuously. It is designed to see if a next-generation sensor is accurate and safe for people with diabetes.
Chula Vista, CaliforniaAges 2–80 - NCT05801614Recruiting
Tested diet to help control glucose in early type 2 diabetes
This study tests whether carbohydrate or calorie restriction can help normalize blood sugar levels in people with relatively early type 2 diabetes. It may help those whose diabetes control is not yet fully under control but who do not have major recent heart problems.
StockholmAges 24–70 - NCT05604560RecruitingPhase 2
New drug combo before surgery for resectable pancreatic cancer
This trial tests two drugs, tislelizumab and SX-682, given before surgery for people with pancreatic cancer that can be removed. The goal is to see if this combination shrinks tumors and improves outcomes.
Baltimore, MarylandAges 18 years+ - NCT07866391Enrolling by invitation
Vitamin D levels in Zhejiang province
This study looks at vitamin D levels in people in Zhejiang province, China. It aims to understand what factors affect vitamin D levels.
Hangzhou, ZhejiangAges Any age - NCT07860203Recruiting
Nerve block and sedation drug for better sleep after gynecologic surgery
This study tests whether a nerve block in the neck plus a sedation medication can improve sleep quality after laparoscopic gynecologic surgery. It may help reduce sleep problems and promote recovery.
Huai'an, JiangsuAges 18–75 - NCT05446545Recruiting
Blood and tissue tests to monitor ovarian cancer using tumor DNA
This study uses a custom lab test on blood (and tumor tissue) to track ovarian cancer returning and to see how well treatment is working. It may help your care team monitor changes over time, especially after certain surgeries.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT03132129Recruiting
Heart imaging study in adults with type 2 diabetes
This study looks for early, “silent” changes in heart function in adults with type 2 diabetes, even if you feel okay. It uses heart scans and looks for factors that may help explain why these changes happen.
LeicesterAges 50–75 - NCT06088030RecruitingPhase 2
Arsenic trioxide plus chemo for p53-mutated childhood cancer
This trial tests if adding arsenic trioxide to standard chemotherapy can help children with cancers that have a certain p53 gene change. The goal is to see if the drug can reactivate the broken p53 protein to fight the tumor.
Guangzhou, GuangdongAges Up to 18 years - NCT02590822Recruiting
Assess weight loss or exercise to improve heart function in diabetes
This study tests whether slimming (weight loss) or training (exercise) can improve early, “hidden” heart and blood-vessel problems in people with type 2 diabetes. It may help find a safer way to protect the heart by improving risk factors.
LeicesterAges 18–65 - NCT06192251Recruiting
Lifestyle medicine program for chronic conditions
This trial tests a complete lifestyle medicine program to help people with conditions like prediabetes, diabetes, high blood pressure, heart disease, high cholesterol, or being overweight. The program aims to improve your overall health through diet, exercise, and other lifestyle changes.
Parry Sound, OntarioAges 18 years+ - NCT04884620Recruiting
Copenhagen puberty study for healthy Caucasian youth
This study looks at how puberty changes happen in healthy children and teens. By tracking normal development, researchers hope to better understand puberty timing and patterns.
CopenhagenAges 5–19 - NCT06198842RecruitingPhase 2
Low-dose treosulfan with PTCy for Nijmegen Breakage Syndrome transplant
This trial tests a low-dose chemotherapy regimen (treosulfan) combined with a drug called PTCy to prepare children with Nijmegen Breakage Syndrome for a stem cell transplant. The goal is to reduce side effects while helping the donor cells take hold safely.
MoscowAges 3 months–21 years - NCT06047496RecruitingEarly Phase 1
Time-restricted eating for sleep apnea
This study tests whether limiting your eating to a shorter daily window can improve health in people with untreated moderate to severe sleep apnea. You would eat all your meals within a set number of hours each day while tracking your progress on your smartphone.
La Jolla, CaliforniaAges 18–70 - NCT06450730Recruiting
Smartphone support program for young people with type 1 diabetes
This study tests a smartphone app plus talk therapy to help young people with type 1 diabetes feel better emotionally. You would use the app and have virtual sessions to learn ways to cope with diabetes.
Córdoba, CórdobaAges 6–18 - NCT07868432Enrolling by invitation
How artificial sweeteners affect blood sugar in prediabetes
This study looks at how non-nutritive sweeteners (like aspartame or sucralose) affect blood sugar levels in people with prediabetes. It aims to see if these sweeteners change gut bacteria and, in turn, blood sugar control.
Boston, MassachusettsAges 35 years+ - NCT06746714Recruiting
Preventing low blood sugar in high-risk type 2 diabetes
This study tests a program to help people with type 2 diabetes who are at high risk for low blood sugar (hypoglycemia) avoid dangerous drops. It may help you better manage your blood sugar and reduce worrying episodes.
Pleasanton, CaliforniaAges 18 years+ - NCT05798494Recruiting
Pre-pregnancy weight loss plan to protect child weight
This study tests whether a very low-calorie weight loss program before pregnancy can improve the chance that a child will have a healthier weight later. It follows families and stores samples from the child at home.
AarhusAges 18–38 - NCT06213402Recruiting
European registry for rare anemia disorders
This study is creating a European registry (database) to collect information about people with rare anemia disorders. By joining, you help researchers better understand these conditions and improve care for yourself and others.
Barcelona, CataloniaAges birth–100 years - NCT06215950RecruitingPhase 1
CAR-T cell therapy for advanced gynecologic cancer with CD70 protein
This trial tests a new treatment called CAR-T cells that target a protein called CD70 found on some gynecologic cancer cells. It is for people whose cancer has advanced or spread and has not responded to or stopped responding to standard treatments.
Wuhu, AnhuiAges 18 years+ - NCT06215352Recruiting
Meal timing and blood sugar during pregnancy
This study looks at how when and what you eat during early pregnancy affects your blood sugar levels. It may help find ways to improve glucose control for expecting mothers.
Taipei, Zhongzheng DistrictAges 20 years+ - NCT04282083Recruiting
Registry for adults with confirmed digestive neuroendocrine tumors
This is a registry study that collects medical information from adults with neuroendocrine tumors (NETs) that start in the digestive organs. It helps researchers understand these cancers better and may support future studies.
Rozzano, MilanAges 18 years+ - NCT07866326Recruiting
Adrenal function in rheumatoid arthritis patients on low-dose steroids
This study looks at how well your adrenal glands work if you have rheumatoid arthritis and are taking a low dose of corticosteroids (steroids). It aims to see if these treatments affect your adrenal function and to identify what factors might be linked to any problems.
Bursa, YıldırımAges 18–65 - NCT05746897RecruitingPhase 1
First-in-human test of an anti-PVRIG drug for advanced cancers
This early-phase study tests NM1F (an anti-PVRIG antibody) in people with advanced solid tumors to see if it’s safe and whether it may work. It also includes pembrolizumab (a PD-1 “checkpoint” medicine), aiming to boost the immune system against the cancer.
Dallas, TexasAges 18 years+
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,607 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,814 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.