Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,230 recruiting studies in this area right now.
By phase
- Not applicable3,147
- Phase 21,063
- Phase 1819
- Phase 1/Phase 2442
- Phase 3425
- Phase 4238
- Phase 2/Phase 396
Top conditions
- Multiple Sclerosis343
- Multiple Myeloma332
- Asthma194
- Lymphoma182
- Rheumatoid Arthritis140
- Type 1 Diabetes133
- Atopic Dermatitis129
- Systemic Lupus Erythematosus125
- Acute Lymphoblastic Leukemia122
- HIV Infections116
- Chronic Lymphocytic Leukemia100
- Autoimmune Diseases81
- Follicular Lymphoma74
- Diabetes Mellitus, Type 169
- Hodgkin Lymphoma67
- Rheumatoid Arthritis (RA)66
- Leukemia64
- Type 1 Diabetes Mellitus63
Leading sponsors
- Institute of Hematology & Blood Diseases Hospital, China91
- National Institute of Allergy and Infectious Diseases (NIAID)90
- National Cancer Institute (NCI)73
- Assistance Publique - Hôpitaux de Paris70
- M.D. Anderson Cancer Center63
- Novartis Pharmaceuticals60
- AstraZeneca57
- City of Hope Medical Center47
- Mayo Clinic46
- Memorial Sloan Kettering Cancer Center44
Where studies are running
- California491
- Maryland195
- Alabama175
- Florida144
- Arizona142
- New York123
- Massachusetts119
- Texas118
- Illinois81
- Colorado77
Recruiting studies6,230 total
- NCT06376149Recruiting
Making Mindfulness Matter for Kids with JIA
This study tests a program called Making Mindfulness Matter (M3) for children with JIA. It is an online program that helps children and their caregivers learn mindfulness skills to manage pain and stress from arthritis.
Hamilton, OntarioAges 4–12 - NCT06376214Recruiting
Daratumumab for newly diagnosed light chain amyloidosis
This trial tests the drug daratumumab in people newly diagnosed with light chain amyloidosis that affects the heart, kidney, or liver. The goal is to see if daratumumab can help control the disease. Eligibility depends on your disease stage and overall health.
Nanjing, JiangsuAges 18–75 - NCT06376721RecruitingPhase 1/Phase 2
Linperlisib combo for advanced NK/T-cell lymphoma
This trial tests a combination of three drugs (linperlisib, camrelizumab, and pegaspargase) for people with a rare type of lymphoma called ENKTL. It is for patients whose cancer has not responded to treatment or has come back, or who are newly diagnosed with advanced disease.
Beijing, Beijing MunicipalityAges 18–75 - NCT06377345Recruiting
Remote monitoring for asthma flare-ups
This trial tests a remote monitoring device that tracks your breathing while you're at home. If you have asthma and are having a flare-up today, you may be able to use a small wearable sensor and a smartphone app to help your doctor keep an eye on your condition.
SingaporeAges 7–90 - NCT06377566RecruitingPhase 2
BV-AVD for bulky Hodgkin lymphoma
This trial tests a combination of two drugs (brentuximab vedotin, AVD chemotherapy) for people with newly diagnosed, bulky Hodgkin lymphoma that hasn't spread far. It aims to see if this treatment works well for larger tumors.
Miami, FloridaAges 18 years+ - NCT06378190RecruitingPhase 1/Phase 2
New CAR-T cell therapy for relapsed B-cell lymphoma
This trial tests a new type of CAR-T cell therapy (a treatment that uses your own immune cells to fight cancer) for people with B-cell lymphomas that have come back or not responded to standard treatments. It aims to see if this new manufacturing method is safe and effective.
Barcelona, BarcelonaAges 18–80 - NCT06379282Recruiting
Diet and exercise study for CLL patients
This study looks at how changing your diet and exercise routine affects your health if you have CLL. It's testing whether a personalized energy balance plan can help you feel better and manage your disease.
GuildfordAges 18 years+ - NCT06379646Recruiting
YTS109 cell therapy for autoimmune disease
This study tests a new cell therapy (YTS109) for people with autoimmune diseases like lupus or Sjogren's syndrome that have not improved or keep coming back after standard treatments. It aims to see if the treatment can help control the disease.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT06380673Recruiting
Step-by-step cooked milk introduction for cow's milk allergy
This study tests a step-by-step approach to help children with cow's milk allergy safely eat more forms of milk. Children will start with very well-cooked milk and, if they tolerate it, slowly move to less cooked forms, aiming to build tolerance.
BonheidenAges 1–18 - NCT06381219Recruiting
Heating milk or egg for kids with EoE
This study tests whether heating cow's milk or hen's egg (like baking them) can help children with EoE stay in remission. It's for children whose EoE is triggered by these foods and who are currently doing well (no active EoE).
Leuven, Vlaams-BrabantAges 1–18 - NCT06381453RecruitingPhase 2
Belimumab for autoimmune hepatitis
This trial tests a drug called belimumab for people with autoimmune hepatitis that is not well controlled. It aims to see if adding belimumab to your current treatment can help reduce liver inflammation.
Calgary, AlbertaAges 18–80 - NCT06381817RecruitingPhase 3
Stem cell transplant comparison for T-cell leukemia
This study compares two types of stem cell transplants for adults with T-ALL: one using a half-matched donor alone, and one using a half-matched donor plus umbilical cord blood. The goal is to see which approach gives better results with fewer side effects.
Suzhou, JiangsuAges Any age - NCT06382350Recruiting
Blood sugar changes while driving with a closed-loop insulin pump
This study looks at how blood sugar levels change while driving in people with type 1 diabetes who use a closed-loop insulin pump (MiniMed 780G) compared to those who give multiple daily injections and use a continuous glucose monitor. The goal is to see which method helps keep blood sugar more stable during driving.
PragueAges 18 years+ - NCT06382675Recruiting
Testing a new plasma filter for blood cleaning treatment
This trial tests a new plasma filter, PX2, used in a procedure called therapeutic plasma exchange (TPE) to clean harmful substances from your blood. It’s for people who already need TPE and can safely use a blood thinner during the treatment.
Aschaffenburg, BavariaAges 18 years+ - NCT06382844Recruiting
Better detection of tumor cells in cutaneous T-cell lymphoma
This study uses advanced blood tests (flow cytometry) to find cancer cells more accurately in people with cutaneous T-cell lymphoma. It could lead to better monitoring of your condition.
SalamancaAges 18 years+ - NCT06383143Recruiting
Improving diagnosis and care for AL amyloidosis and related conditions
This study is for people who are newly diagnosed with either a very early blood condition (MGUS or smoldering myeloma) or AL amyloidosis, and who have not yet had treatment. It aims to help doctors better diagnose and manage these conditions in Italy.
BariAges 18–99 - NCT06384911Recruiting
Helping Teens Invest in Diabetes Care
This study tests whether offering small rewards and education can help teenagers with type 1 diabetes check their blood sugar more often and give themselves more insulin before meals. It's designed for teens who are having trouble using their CGM or giving enough insulin.
Seattle, WashingtonAges 12 years+ - NCT06385236RecruitingPhase 4
Asthma genetics study to find better treatments
This study looks at how your genes affect your asthma medications. It tests if knowing your DNA can help predict which treatment works best for you and why.
Scottsdale, ArizonaAges 18–75 - NCT06385652RecruitingEarly Phase 1
PET Imaging of Multiple Myeloma with 68Ga-NB381
This study uses a special PET scan to look for multiple myeloma in your body. It may help doctors see where the disease is and how active it is.
Beijing, Beijing MunicipalityAges 18–90 - NCT06387030Recruiting
EoE biopsy study during endoscopy
This trial looks at taking a small tissue sample during a routine endoscopy to better understand eosinophilic esophagitis (EoE). It may help doctors learn how to diagnose and track EoE more easily.
ParisAges 2–17 - NCT06387121RecruitingPhase 2
Low-dose chemo plus immune drugs for new B-ALL
This trial tests a combination of low-dose chemotherapy and immune-targeted drugs for adults newly diagnosed with a specific type of leukemia. The goal is to find a treatment that is effective with fewer side effects.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT06387199RecruitingPhase 2/Phase 3
Weekly semaglutide with closed-loop system for type 1 diabetes
This trial tests whether adding a weekly semaglutide injection (a GLP-1 drug) to a closed-loop insulin system can help reduce the need for carb counting in people with type 1 diabetes. It aims to improve blood sugar control and make diabetes management easier.
Montreal, QuebecAges Any age - NCT06388460Recruiting
Asthma Link study for children with asthma
This study tests a program called 'Asthma Link' to help children with asthma take their daily medicine more consistently. It is for children ages 5–14 whose asthma is not well controlled and who sometimes forget their medication.
Worcester, MassachusettsAges 5–14 - NCT06388161Recruiting
Autoantibody study in new focal seizures
This research study looks for specific immune system markers (autoantibodies) in the blood and spinal fluid of people who have recently started having focal seizures (seizures that start in one part of the brain) with no known cause. Finding these markers could help doctors understand why the seizures started.
Hangzhou, ZhejiangAges 14–100
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,230 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,763 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.