Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,230 recruiting studies in this area right now.
By phase
- Not applicable3,147
- Phase 21,063
- Phase 1819
- Phase 1/Phase 2442
- Phase 3425
- Phase 4238
- Phase 2/Phase 396
Top conditions
- Multiple Sclerosis343
- Multiple Myeloma332
- Asthma194
- Lymphoma182
- Rheumatoid Arthritis140
- Type 1 Diabetes133
- Atopic Dermatitis129
- Systemic Lupus Erythematosus125
- Acute Lymphoblastic Leukemia122
- HIV Infections116
- Chronic Lymphocytic Leukemia100
- Autoimmune Diseases81
- Follicular Lymphoma74
- Diabetes Mellitus, Type 169
- Hodgkin Lymphoma67
- Rheumatoid Arthritis (RA)66
- Leukemia64
- Type 1 Diabetes Mellitus63
Leading sponsors
- Institute of Hematology & Blood Diseases Hospital, China91
- National Institute of Allergy and Infectious Diseases (NIAID)90
- National Cancer Institute (NCI)73
- Assistance Publique - Hôpitaux de Paris70
- M.D. Anderson Cancer Center63
- Novartis Pharmaceuticals60
- AstraZeneca57
- City of Hope Medical Center47
- Mayo Clinic46
- Memorial Sloan Kettering Cancer Center44
Where studies are running
- California491
- Maryland195
- Alabama175
- Florida144
- Arizona142
- New York123
- Massachusetts119
- Texas118
- Illinois81
- Colorado77
Recruiting studies6,230 total
- NCT06433765Recruiting
BRIUMVI and pregnancy safety in multiple sclerosis
This study looks at the effects of the MS medication BRIUMVI on pregnancy and baby health. It compares women who took BRIUMVI during pregnancy to those who did not.
Wilmington, North CarolinaAges 15–50 - NCT06433947RecruitingPhase 1
Testing an experimental drug OPN-6602 for advanced multiple myeloma
This trial tests an experimental oral drug called OPN-6602 for people with multiple myeloma that has come back or stopped responding to at least three prior treatments. The main goal is to see if the drug is safe and tolerable, and to find the best dose.
Gilbert, ArizonaAges 18 years+ - NCT06433921RecruitingPhase 1
Comparing two asthma rescue inhalers with different propellants
This study compares two versions of the common asthma rescue inhaler (salbutamol/albuterol) that use different propellants (the gas that pushes the medicine out). The goal is to see if the new propellant works as well as the current one. If you have mild asthma and are on a stable treatment plan, you may be able to join.
ManchesterAges 18–65 - NCT06434363RecruitingPhase 1/Phase 2
Cell therapy plus tafasitamab for autoimmune diseases
This trial tests a new cell therapy (AD-PluReceptor) combined with the drug tafasitamab for people with certain autoimmune diseases like systemic sclerosis, lupus, or chronic graft-versus-host disease. It aims to see if this treatment can help when standard therapies have failed.
Houston, TexasAges 18 years+ - NCT06434571RecruitingPhase 2
Comparing two sleep treatments for people with MS
This trial tests if talking with a sleep coach by video is better than a web-based program for improving sleep, reducing fatigue, and protecting the brain in people with multiple sclerosis (MS). Both treatments focus on changing thoughts and habits around sleep.
Kansas City, KansasAges 18–65 - NCT06435156RecruitingPhase 2
Sotagliflozin for Heart Failure in Type 1 Diabetes
This trial tests a medication called sotagliflozin for people who have both type 1 diabetes and heart failure symptoms. The goal is to see if it can improve how you feel and manage your heart and diabetes.
AberdeenAges 18–84 - NCT06435468Recruiting
Biocollection for rare childhood-onset immune diseases
This study collects blood and tissue samples from patients with rare immune system diseases that started in childhood, and from their relatives and healthy volunteers. The goal is to build a biocollection for future research to better understand these diseases.
Bron, BronAges 1 year+ - NCT06436456Recruiting
Online program for diabetes distress in type 1 diabetes
This trial tests an online program to help adults with type 1 diabetes who feel stressed or overwhelmed by their diabetes (called diabetes distress). The program is designed to reduce that distress and make living with diabetes a bit easier.
OdenseAges 30 years+ - NCT06436677Recruiting
New treatment plans based on CTCL genetic type
This trial is testing new treatment plans based on the genetic type of your cutaneous T-cell lymphoma (CTCL). It's for people whose CTCL did not respond well to standard skin treatments.
Beijing, Beijing MunicipalityAges 18–75 - NCT06439173Recruiting
Study on bone marrow recovery after CAR-T therapy
This study is looking at why some people develop low blood cell counts after CAR-T therapy for a type of lymphoma. It aims to find ways to help the bone marrow recover and work better.
SalamancaAges 18 years+ - NCT06440148Recruiting
Sclerostin and bone lesions in mastocytosis
This study explores how a protein called sclerostin relates to bone problems in people with mastocytosis. By understanding this link, researchers hope to improve bone health for patients with this rare condition.
Lublin, Lublin VoivodeshipAges 18 years+ - NCT06441123Recruiting
A trial of a new HIV latency-reversing drug
This trial tests a new type of medicine that aims to wake up HIV hiding in your body's cells by targeting a viral protein called Tat. The goal is to help find a way to clear the virus completely.
MontpellierAges 18 years+ - NCT06443346Recruiting
Registry for people with eosinophilic esophagitis
This is a registry (like a medical diary) for people with EoE who are getting regular treatment. It helps doctors track how EoE affects people over time, so they can improve care for everyone.
Milan, LombardyAges Any age - NCT06443515Recruiting
Breathing changes during blood transfusions in newborns
This study watches how breathing changes in newborns during blood transfusions. It helps doctors understand if transfusions affect breathing, so they can give safer care.
RomaAges Up to 1 month - NCT06444841Recruiting
Memory aids for mild memory loss
This study tests whether using a paper-based or smartphone-based memory support system helps people with mild memory problems remember daily tasks. You and a family member or friend will both participate.
Austin, TexasAges 50 years+ - NCT06445803RecruitingPhase 1
CAR-T therapy for adults with certain blood cancers
This trial tests a type of immunotherapy called CAR-T cells that target two proteins (CD19 and CD22) on cancer cells. It may be an option for adults with B-cell acute lymphoblastic leukemia (ALL) or B-cell non-Hodgkin lymphoma (NHL) that has come back or not responded to earlier treatments.
Nanchang, JiangxiAges 18 years+ - NCT06445361Recruiting
Liver fat study in type 1 diabetes
This trial looks at how common fatty liver disease is in people with type 1 diabetes. Doctors will check your liver with tests to learn more and find out if you might be at risk.
Genk, LimburgAges 18 years+ - NCT06446128RecruitingEarly Phase 1
CAR-T cell therapy for B-cell lymphoma that returned or didn't respond
This trial tests a new CAR-T treatment that targets three proteins on lymphoma cells (CD19, CD22, and BCMA). It is for people with certain types of B-cell lymphoma that have come back or are not responding to standard treatments.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06447376RecruitingPhase 1
Testing siltuximab before epcoritamab to prevent cytokine release syndrome
This trial tests whether giving siltuximab before epcoritamab can help prevent or reduce cytokine release syndrome (a possible side effect where the immune system overreacts). It is for people with certain types of non-Hodgkin lymphoma that have not responded well to at least two prior treatments.
Cleveland, OhioAges 18–65 - NCT06447974Recruiting
Environmental health clinic for children with breathing problems
This study tests whether a children's environmental health clinic can help families manage chronic respiratory conditions like asthma. It focuses on your child's home environment and provides follow-up support.
LondonAges 4–17 - NCT06448689Recruiting
Wrist monitor study for itch in eczema and psoriasis
This study tests whether a wrist-worn device can accurately measure scratching during sleep in people with eczema (atopic dermatitis) or psoriasis. It may help doctors better understand and treat nighttime itching.
ParisAges 14–70 - NCT06449573Recruiting
Heart and Lung Health in Asthma
This study looks at how asthma affects your heart and lungs during exercise. It aims to help doctors understand how to better care for people with asthma.
AnkaraAges 18–65 - NCT06449794Recruiting
Brain and behavior issues in children with Lupus
This study looks at brain and behavior problems in children with Lupus (SLE). It aims to understand how often these problems happen and what they look like, so doctors can better care for children with SLE.
SohagAges 1 year+ - NCT06449885Recruiting
Observational study for newly diagnosed MZL
This study is for people who were just diagnosed with marginal zone lymphoma (a slow-growing blood cancer) and haven't started treatment yet. Researchers will collect blood and tissue samples and follow you over time to learn more about the disease.
Shanghai, Shanghai MunicipalityAges 18 years+
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,230 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,763 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.