Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,230 recruiting studies in this area right now.
By phase
- Not applicable3,147
- Phase 21,063
- Phase 1819
- Phase 1/Phase 2442
- Phase 3425
- Phase 4238
- Phase 2/Phase 396
Top conditions
- Multiple Sclerosis343
- Multiple Myeloma332
- Asthma194
- Lymphoma182
- Rheumatoid Arthritis140
- Type 1 Diabetes133
- Atopic Dermatitis129
- Systemic Lupus Erythematosus125
- Acute Lymphoblastic Leukemia122
- HIV Infections116
- Chronic Lymphocytic Leukemia100
- Autoimmune Diseases81
- Follicular Lymphoma74
- Diabetes Mellitus, Type 169
- Hodgkin Lymphoma67
- Rheumatoid Arthritis (RA)66
- Leukemia64
- Type 1 Diabetes Mellitus63
Leading sponsors
- Institute of Hematology & Blood Diseases Hospital, China91
- National Institute of Allergy and Infectious Diseases (NIAID)90
- National Cancer Institute (NCI)73
- Assistance Publique - Hôpitaux de Paris70
- M.D. Anderson Cancer Center63
- Novartis Pharmaceuticals60
- AstraZeneca57
- City of Hope Medical Center47
- Mayo Clinic46
- Memorial Sloan Kettering Cancer Center44
Where studies are running
- California491
- Maryland195
- Alabama175
- Florida144
- Arizona142
- New York123
- Massachusetts119
- Texas118
- Illinois81
- Colorado77
Recruiting studies6,230 total
- NCT06419413Recruiting
Asthma study in Chinese adults to find better treatment matches
This study looks at how asthma affects people in China and tries to find patterns that might help predict which treatments work best. If you have asthma and are between 18 and 75, you may be able to join.
Chengdu, SichuanAges 18–75 - NCT06420076RecruitingPhase 1/Phase 2
Sequential CAR-T therapy for CD5/CD7 positive T-cell leukemia/lymphoma
This trial tests a new type of immune cell therapy (called CAR-T) that targets two proteins, CD5 and CD7, on the surface of T-cell leukemia or lymphoma cells. It may be an option for people whose cancer came back or didn't respond to standard treatment.
Beijing, Beijing MunicipalityAges 2–90 - NCT06420089RecruitingPhase 1
CAR T cells for T-cell lymphoma
This trial tests a new CAR T-cell treatment for T-cell lymphoma that has come back or hasn't responded to standard treatments. The treatment is designed to target cancer cells that have a protein called CD5 on their surface.
New York, New YorkAges 18 years+ - NCT06421948RecruitingPhase 1/Phase 2
Linperlisib and chidamide for PTCL
This trial tests two pills—linperlisib and chidamide—for people with a type of lymphoma called PTCL. The combination might work better together than either alone.
Zhengzhou, HenanAges 18–80 - NCT06421675RecruitingPhase 2
Elranatamab for multiple myeloma that has come back
This trial tests a new drug called elranatamab (given as an outpatient, not in the hospital) for people with multiple myeloma that has come back or stopped responding to several treatments. The goal is to see if taking it less often works well and is safer.
Vancouver, British ColumbiaAges 18 years+ - NCT06421805Recruiting
Mediastinal Tumor Patient Database Study
This study is building a database of people with mediastinal tumors. It will collect health information over time to help doctors better understand these tumors and improve care.
Beijing, Beijing MunicipalityAges Any age - NCT06421987Recruiting
Heart, lung, and brain function in Hodgkin lymphoma survivors
This study looks at how heart, lung, and brain blood flow are affected in adults who survived Hodgkin lymphoma as children. It compares survivors who had certain treatments to healthy volunteers.
Memphis, TennesseeAges 18 years+ - NCT06422078Recruiting
Real-world study of Benralizumab for severe asthma
This study is for people with severe eosinophilic asthma who are about to start a medicine called Benralizumab (Fasenra). It will observe how the medicine works in real life, and requires you to answer some questions about your asthma every week and month.
AhrensburgAges 18–120 - NCT06423131Recruiting
Comparing two types of stem cell transplants for children
This study compares a newer type of stem cell transplant (using special cells) to the standard method for children who need a half-matched donor. It aims to see if the new approach is safer and works as well.
Shanghai, Shanghai MunicipalityAges 2 months–18 years - NCT06424964Recruiting
HIV treatment study for injectable cabotegravir/rilpivirine in Belgium
This study looks at people in Belgium who have already received at least one dose of a long-acting injectable HIV medication called cabotegravir/rilpivirine. The goal is to learn more about how this treatment works in real-world settings.
BrusselsAges 18–99 - NCT06425640Recruiting
Movement and Activity in Adults with Type 1 Diabetes
This study looks at how 24-hour movement patterns (like sitting, standing, walking, and sleeping) affect adults with type 1 diabetes. It may help you understand how your daily activities relate to your blood sugar control.
Ghent, East FlandersAges 25–50 - NCT06425562Recruiting
A new breathing test for asthma monitoring
This study tests a new way of measuring lung function (called impulse oscillometry) during routine asthma check-ups. It looks at whether this helps doctors decide when to change asthma medicines.
BrusselsAges 18 years+ - NCT06426316Recruiting
Immune cells and migraines study
This study looks at how certain immune cells and inflammatory chemicals relate to migraines. If you have migraines or an autoimmune condition (like lupus, rheumatoid arthritis, or Crohn's disease), you may be able to participate. The goal is to understand what causes migraines.
Clermont-Ferrand, AURAAges 18–50 - NCT06427018Recruiting
Proteins in airway smooth muscle of asthma patients
This study looks at two proteins, called Ezrin and Pip5k1α, in the smooth muscle of the airways of people with asthma. By comparing samples from people with and without asthma, researchers hope to understand how these proteins may be involved in asthma.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT06427421Recruiting
Immune cells in children with recent type 1 diabetes
This study looks at immune cells in children who were recently diagnosed with type 1 diabetes. It involves one extra blood draw to better understand how the immune system attacks the pancreas. If you join, no new treatments are given—just observation and analysis of your child's immune cells.
ParisAges 6–18 - NCT06428643Recruiting
Chlamydia Testing and Treatment for Young African Americans
This study tests a program to find and treat chlamydia in young African American people in New Orleans. If you qualify, you may get free testing and treatment to help stop the spread of infection.
New Orleans, LouisianaAges 15–26 - NCT06427330RecruitingPhase 2
Low-Dose Inotuzumab After Transplant to Prevent Leukemia Relapse
This trial tests whether a low dose of a targeted drug called inotuzumab ozogamicin, given after a stem cell transplant, can help prevent acute lymphoblastic leukemia from coming back. It is for people who have already had a transplant and are at high risk for relapse.
TianjinAges 18 years+ - NCT06427577Recruiting
Study of ZhenQiFuZheng for allergic rhinitis
This trial tests if a traditional Chinese medicine called ZhenQiFuZheng can help people with allergic rhinitis by changing their gut bacteria. Researchers will collect samples to understand how it works.
Nanjing, JiangsuAges 18–65 - NCT06428006RecruitingPhase 2
Sleep therapy for insomnia in multiple sclerosis
This study tests whether a talking therapy (cognitive behavioral therapy for insomnia) can help people with multiple sclerosis who have trouble sleeping. It is done online, so you can join from home.
Kansas City, KansasAges 18–65 - NCT06428019RecruitingPhase 3
Comparing drug combinations for untreated CLL or SLL
This trial tests two different drug combinations (venetoclax with obinutuzumab or with acalabrutinib) to see how they affect the risk of tumor lysis syndrome in people with untreated CLL or SLL. It may help find the safest and most effective way to start treatment.
Tucson, ArizonaAges 18 years+ - NCT06428188RecruitingPhase 1/Phase 2
CAR-T cells targeting BCMA/CD19 for autoimmune diseases
This trial tests a new treatment called CAR-T cells that target two proteins (BCMA and CD19) on immune cells. It is for people with certain autoimmune diseases that have not improved with standard treatments.
Beijing, Beijing MunicipalityAges 21–90 - NCT06429475RecruitingPhase 3
Anti-inflammatory reliever for asthma in children and teens
This study tests a new way to treat asthma flares in children and teens (ages 6–18) with mild-to-moderate asthma. It aims to see if a quick-relief anti-inflammatory medicine works better than current treatments to prevent severe attacks.
Mtubatuba, KwaZulu-NatalAges 6–18 - NCT06430736RecruitingPhase 2
Tocilizumab before or during CAR-T therapy
This study tests whether giving tocilizumab (a drug that calms inflammation) before CAR-T cell therapy helps prevent side effects. It compares using it ahead of time versus only when needed. You may be eligible if you are scheduled for CAR-T therapy for lymphoma, leukemia, or myeloma.
Bern, Canton of BernAges 18 years+ - NCT06433362RecruitingPhase 2
Chemo combo for untreated Peripheral T-cell lymphoma
This trial is testing a new combination of chemotherapy drugs (CMOEP) for people with untreated Peripheral T-cell lymphoma. It aims to see if this treatment is safe and effective.
TianjinAges 18–70
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,230 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,763 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.