Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,236 recruiting studies in this area right now.
By phase
- Not applicable3,144
- Phase 21,066
- Phase 1823
- Phase 1/Phase 2446
- Phase 3426
- Phase 4238
- Phase 2/Phase 393
Top conditions
- Multiple Sclerosis345
- Multiple Myeloma334
- Asthma194
- Lymphoma183
- Rheumatoid Arthritis141
- Type 1 Diabetes131
- Atopic Dermatitis129
- Systemic Lupus Erythematosus126
- Acute Lymphoblastic Leukemia123
- HIV Infections117
- Chronic Lymphocytic Leukemia100
- Autoimmune Diseases81
- Follicular Lymphoma74
- Diabetes Mellitus, Type 170
- Hodgkin Lymphoma67
- Leukemia64
- Rheumatoid Arthritis (RA)64
- Mantle Cell Lymphoma62
Leading sponsors
- Institute of Hematology & Blood Diseases Hospital, China91
- National Institute of Allergy and Infectious Diseases (NIAID)91
- National Cancer Institute (NCI)74
- Assistance Publique - Hôpitaux de Paris70
- Novartis Pharmaceuticals65
- M.D. Anderson Cancer Center63
- AstraZeneca57
- City of Hope Medical Center46
- Mayo Clinic46
- Memorial Sloan Kettering Cancer Center45
Where studies are running
- California492
- Maryland196
- Alabama179
- Arizona141
- Florida141
- New York122
- Massachusetts120
- Texas119
- Illinois82
- Colorado77
Recruiting studies6,236 total
- NCT07604220Recruiting
Exosome Signatures in Cardiac Sarcoidosis Disease Activity
This study looks for disease markers in tiny particles called exosomes in your blood to better understand cardiac sarcoidosis (a condition where inflammation affects the heart). By measuring these markers alongside your standard heart imaging, researchers hope to find better ways to detect and monitor the disease.
Rochester, MinnesotaAges 18 years+ - NCT07282574RecruitingPhase 2
Testing a new study drug for progressive MS
This trial tests a new study drug added to your current MS treatment (ocrelizumab) for people with progressive MS. It aims to see if the combination works better than ocrelizumab alone.
Camperdown, New South WalesAges 18–60 - NCT07246031RecruitingPhase 2
BPC2001 to Prevent Graft-Versus-Host Disease After Stem Cell Transplant
This trial tests a new drug, BPC2001, to see if it can prevent graft-versus-host disease (a common complication where donor cells attack the patient's body) in people receiving a half-matched stem cell transplant from a family donor. It may be an option for adults with certain blood cancers who are planning their first transplant.
Beijing, Beijing MunicipalityAges 18–65 - NCT07359846RecruitingPhase 3
Study of GB-0895 for severe uncontrolled asthma in adults and teens
This trial tests an add-on treatment called GB-0895 for people with severe asthma that is not well controlled with current medications. It aims to see if adding this drug can reduce asthma attacks and improve lung function.
Bakersfield, CaliforniaAges 12–80 - NCT06927466RecruitingPhase 1
B019 for relapsed or refractory B-cell acute lymphoblastic leukemia
This trial tests a new treatment called B019 for people whose B-cell acute lymphoblastic leukemia has come back or not responded to standard therapy. The treatment targets specific proteins on the cancer cells to help your immune system fight the leukemia.
BeijingAges 3–25 - NCT07660835RecruitingPhase 2
A study of nemolizumab for babies with eczema
This trial tests a medicine called nemolizumab for babies aged 6 to 23 months with moderate to severe eczema. The goal is to see if it reduces itching and improves skin symptoms.
San Antonio, TexasAges 6 months–1.9 years - NCT06274788Recruiting
Safety study of long-term Omegaven for liver problems from IV nutrition
This study checks if children who need Omegaven for eight weeks or longer develop a lack of essential fats. It is for kids with liver issues caused by IV nutrition who cannot eat or digest food normally.
Fountain Valley, CaliforniaAges 1 day–17 years - NCT07764978RecruitingPhase 3
New drug combo for multiple myeloma without stem cell transplant
This trial tests a new drug called AZD0120 added to standard treatments for people newly diagnosed with multiple myeloma who are not eligible for a stem cell transplant. It aims to see if the combination can better control the disease and improve outcomes.
Gilbert, ArizonaAges 18 years+ - NCT06865339RecruitingPhase 2
Radiation plus immunotherapy for advanced lung cancer
This trial tests whether adding two immunotherapy drugs (cemiplimab and fianlimab) to standard radiation and chemotherapy can help treat locally advanced non-small cell lung cancer that hasn't been treated before.
The Bronx, New YorkAges 18 years+ - NCT06812091Recruiting
Study on microbiome in children
This study explores the role of the microbiome (the community of bacteria in our bodies) in children's health. It aims to develop new treatments for pediatric diseases.
SeoulAges Any age - NCT05801978RecruitingPhase 4
How long a vaccine’s immune response lasts in adults
This study checks how long your body’s protection signals last after a vaccine. It may help researchers understand which vaccines give longer-lasting immune responses and who may need boosters.
Atlanta, GeorgiaAges 18–50 - NCT01299168Recruiting
Testing kidney transplant biopsy samples for better care
This study looks at kidney biopsy samples from adult kidney transplant recipients to help improve how transplant-related problems are diagnosed and treated. If you need a biopsy for medical reasons, you may be invited to participate.
Birmingham, AlabamaAges 18 years+ - NCT07282665RecruitingPhase 3
Vaccine to prevent C. difficile infection in adults 65 and older
This study tests a vaccine that may help protect against a serious gut infection called C. difficile, which often happens after antibiotics or hospital stays. If you are 65 or older and have certain health conditions or recent antibiotic use, you may be able to join.
Athens, AlabamaAges 65 years+ - NCT07765979Recruiting
Diet plans for teenage hives
This study tests two diets — a Mediterranean diet and a low-histamine diet — to see if they help reduce hives in teenagers with chronic spontaneous urticaria. If your child qualifies, they will follow one of these diets for a period and we will monitor their symptoms.
IstanbulAges 12–18 - NCT06651970RecruitingPhase 4
Acalabrutinib for chronic lymphocytic leukemia with heart problems
This trial tests a targeted therapy called acalabrutinib (a pill) against other standard treatments for chronic lymphocytic leukemia (CLL) in people who also have heart conditions. The goal is to see if acalabrutinib is a safer or more effective option for this group.
Charlotte, North CarolinaAges 18–130 - NCT07393659RecruitingPhase 3
Continued access to HIV treatment after a parent study
This study lets people who finished an earlier HIV treatment study keep getting the same medicine while a new trial is set up. It helps ensure you don't have a gap in your treatment.
Durban, KwaZulu-NatalAges Any age - NCT06149286RecruitingPhase 3
Comparing two drug combos for relapsed follicular or marginal zone lymphoma
This trial tests whether a new drug, odronextamab, combined with lenalidomide works better than the current standard, rituximab combined with lenalidomide, for people whose follicular or marginal zone lymphoma has come back or not responded to prior treatment. It aims to see which combo is safer and more effective.
Los Angeles, CaliforniaAges 18 years+ - NCT07256704Recruiting
Hypnosis and attention for neurological conditions
This study looks at whether hypnosis can help improve attention in people with conditions like stroke, traumatic brain injury, or multiple sclerosis. It may help if you have trouble concentrating or focusing.
LucerneAges 18 years+ - NCT07463209Recruiting
Diabetes education with continuous glucose monitoring for older adults
This study tests whether adding continuous glucose monitoring (CGM) to diabetes education helps older adults with diabetes manage their blood sugar better. You and a care partner will learn how to use CGM and support each other.
Chapel Hill, North CarolinaAges 65 years+ - NCT05974202Recruiting
Brain stimulation and therapy for cocaine use
This study tests a combination of brain stimulation (rTMS) and talk therapy (CBT) to help people reduce cocaine use. It's for adults who want treatment and use cocaine at least once a week.
New York, New YorkAges 22–65 - NCT05958381Recruiting
Brain stimulation for memory problems in relapsing MS
This trial studies a noninvasive brain stimulation treatment to improve memory (specifically memory recall) in people with relapsing-remitting multiple sclerosis (RRMS). It may help if your memory testing shows a “retrieval” problem, and if you’re able to follow the study treatment and safety requirements.
Richardson, TexasAges 18–65 - NCT05502653Recruiting
Study inflammation, lung function, and fungal movement in HIV
This study looks at how body inflammation and lung health relate to the movement of fungi in the body of people living with HIV. The goal is to better understand what factors may affect lung problems and fungal “translocation,” which may help future care.
Pittsburgh, PennsylvaniaAges 18–80 - NCT07113743Enrolling by invitationPhase 1/Phase 2
Gene therapy for x-linked chronic granulomatous disease
This trial tests a new gene therapy for X-linked chronic granulomatous disease (CGD), a condition where the immune system cannot fight certain infections. The treatment uses your own blood stem cells, which are modified in the lab to help your body produce working immune cells.
Bethesda, MarylandAges 3–60 - NCT07623668RecruitingPhase 3
Testing a new drug for sudden vision loss from nerve inflammation
This study tests whether a new medication called privosegtor can help restore vision in people who recently experienced sudden vision loss in one eye due to optic nerve inflammation. You would receive the study drug early after your symptoms start, when treatment may be most effective.
Livonia, MichiganAges 18–50
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,236 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,675 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.