Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,051 recruiting studies in this area right now.
By phase
- Not applicable2,997
- Phase 21,057
- Phase 1792
- Phase 1/Phase 2437
- Phase 3436
- Phase 4234
- Phase 2/Phase 398
Top conditions
- Multiple Sclerosis330
- Multiple Myeloma327
- Asthma193
- Lymphoma178
- Rheumatoid Arthritis132
- Type 1 Diabetes130
- Atopic Dermatitis125
- Systemic Lupus Erythematosus119
- Acute Lymphoblastic Leukemia118
- HIV Infections106
- Chronic Lymphocytic Leukemia95
- Autoimmune Diseases77
- Follicular Lymphoma70
- Rheumatoid Arthritis (RA)68
- Diabetes Mellitus, Type 163
- Hodgkin Lymphoma63
- Leukemia63
- Mantle Cell Lymphoma62
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)97
- Institute of Hematology & Blood Diseases Hospital, China85
- National Cancer Institute (NCI)74
- Assistance Publique - Hôpitaux de Paris65
- AstraZeneca63
- M.D. Anderson Cancer Center58
- Novartis Pharmaceuticals58
- Mayo Clinic49
- City of Hope Medical Center48
- Memorial Sloan Kettering Cancer Center45
Where studies are running
- California496
- Maryland200
- Alabama178
- Florida149
- Arizona147
- Massachusetts116
- New York116
- Texas112
- Illinois83
- Colorado82
Recruiting studies6,051 total
- NCT02973412Recruiting
How sleep timing affects blood sugar in diabetes
This study looks at your daily sleep–wake timing (“chronotype”) and how it may affect blood sugar control in people with diabetes. It may help researchers learn whether sleep patterns could improve glucose levels.
LeicesterAges 18–75 - NCT05215704Recruiting
Lab study of dormant HIV using samples from you
This trial collects blood samples from people living with HIV to study dormant (inactive) HIV cells in the lab. The goal is to better understand how to target these hidden cells as part of an eventual cure.
RotterdamAges 18 years+ - NCT04955899Recruiting
Testing a device that stimulates the spleen in rheumatoid arthritis
This trial studies whether splenic stimulation (using a medical device to stimulate the spleen) is safe for people with active rheumatoid arthritis. It may help some patients who have not improved enough after at least two other advanced arthritis medicines.
AmsterdamAges 22–75 - NCT06263530Recruiting
Blood test for tumor DNA in Hodgkin lymphoma
This study looks at whether a blood test that checks for tiny pieces of tumor DNA (called ctDNA) can help predict how Hodgkin lymphoma will progress. It is for adults who have just been diagnosed with classical Hodgkin lymphoma.
Hradec KrálovéAges 18 years+ - NCT04553276Enrolling by invitation
Severe asthma study for UK patients
This study looks at people with severe asthma who also have other health conditions. It aims to understand how these conditions affect asthma and its treatment.
BelfastAges 16 years+ - NCT07860021RecruitingPhase 2/Phase 3
Vyvgart for stiff person syndrome
This trial tests whether a drug called Vyvgart (hyaluronidase-fjjo) can help people with stiff person syndrome who still have symptoms like stiffness, painful muscle spasms, and trouble walking despite other treatments. The goal is to see if it improves these symptoms and how well it works.
Philadelphia, PennsylvaniaAges 25–80 - NCT06267781Recruiting
MS progression and immune cells after bone marrow transplant and other therapies
This study looks at how well different treatments, including bone marrow transplant, alemtuzumab, ocrelizumab, and ofatumumab, work for people with relapsing-remitting MS who have active disease. It will help doctors understand which therapy might slow disease progression best.
MilanAges 18 years+ - NCT06279026Recruiting
Testing UTAA17 for advanced multiple myeloma
This trial tests a new treatment called UTAA17 that targets a protein on myeloma cells. It may be an option for people whose multiple myeloma has not responded to several prior treatments.
Suzhou, JiangsuAges 18 years+ - NCT07388563RecruitingPhase 1
Combination drug therapy for returning T-cell lymphoma
This trial tests two drugs, azacitidine and abatacept, given together for T-cell lymphoma that has come back or not improved after earlier treatment. The goal is to see if this combination can control the cancer better, potentially offering a new option for patients.
Bethesda, MarylandAges 18–120 - NCT07858214Enrolling by invitation
Measuring eye tremors with a new device
This study tests a new device that measures tiny, natural eye movements (tremors) to see if it works well in a diverse group of people. It may help with future diagnosis and monitoring of certain health conditions.
Atlanta, GeorgiaAges 18 years+ - NCT06275373Recruiting
Teprotumumab for thyroid eye disease study
This study tests if the drug teprotumumab can help with symptoms of thyroid eye disease, such as bulging eyes, pain, or double vision. It is for adults who are beneficiaries of the Department of Defense (DOD).
Bethesda, MarylandAges 18 years+ - NCT06277427Recruiting
CAR-T cell therapy for refractory vasculitis and lupus nephritis
This trial tests a new type of cell therapy called CAR-T cells that target BCMA (a protein on certain immune cells) for people with two autoimmune diseases: ANCA-associated vasculitis and lupus nephritis. It is for patients whose disease has not responded to standard treatments or has come back after initial improvement.
Wuhan, HubeiAges 18–70 - NCT05805566Recruiting
Study of care for long COVID symptoms in adults
This study follows people who enter a specialized care pathway for long COVID (post-COVID syndrome) to better understand symptoms, needs, and outcomes. It may help improve how multidisciplinary care is organized for long COVID over time.
Pierre-BéniteAges 18 years+ - NCT06068179RecruitingPhase 2/Phase 3
Can a new combo help Graves' disease go into remission?
This trial tests a combination of two medicines (methimazole and mycophenolate) to see if they can help people with newly diagnosed Graves' disease go into remission faster and more safely. If you are newly diagnosed and haven't had treatment yet, this study might offer a way to get better control of your condition.
Xiamen, FujianAges 18–60 - NCT07861204RecruitingPhase 2/Phase 3
Combination treatment for primary membranous nephropathy
This trial tests a combination of two medications, rituximab and cyclosporine, for people with primary membranous nephropathy, a kidney disease that causes protein in the urine. The goal is to see if this combination can reduce protein loss and improve kidney function, potentially preserving kidney health.
BeijingAges 18–80 - NCT04011020RecruitingPhase 3
Stem cell treatment for type 1 diabetes
This study tests a treatment that uses a patient's own immune cells to help the body make more insulin. It may help people with type 1 diabetes manage their blood sugar better.
Paramus, New JerseyAges 10 years+ - NCT05198661Recruiting
Blood or spinal fluid study in autoimmune brain disorders
This study collects information from people with autoimmune encephalitis or related nerve/brain disorders, using blood and sometimes spinal fluid. It helps researchers better understand these conditions, which may guide future diagnosis and treatments.
Pointe à Pitre, GuadeloupeAges Any age - NCT06283316Recruiting
A registry for alopecia areata treatments
This trial is a registry that collects information from people with alopecia areata who are starting or using body-wide treatments. It helps doctors learn more about how these treatments work in real life.
RotterdamAges 16 years+ - NCT07313592Recruiting
Genome sequencing study for ALL patients
This study uses whole genome sequencing to analyze your leukemia's DNA. The goal is to find unique genetic changes that may help guide future treatments, though this study does not recommend any specific therapy.
St Louis, MissouriAges Up to 30 years - NCT03131531Recruiting
Lymphoid cancer registry for lymphoma and myeloma patients
This study is a cancer registry that collects information from people with lymphoma, Hodgkin disease, or myeloma. It helps researchers understand these cancers better by using real-world patient data.
BergamoAges 18 years+ - NCT05789901Recruiting
Using a Facebook chatbot to share health information
This study tests whether a Facebook Messenger chatbot can provide helpful health information for different conditions. You may help researchers check if people can use the chatbot and understand the information.
Montreal, QuebecAges 14 years+ - NCT05708300Recruiting
Testing how mepolizumab works for people with nasal polyps
This study looks at blood and other measures (biomarkers) to understand how well mepolizumab helps people with nasal polyps, with or without asthma. It aims to find response clues that could help personalize treatment in the future.
Thessaloniki, ExochiAges 18 years+ - NCT06298448Recruiting
Ear, nose, and throat inflammation study in eGPA
This study looks at inflammation in the ear, nose, and throat area in people with different conditions, including nasal polyps, severe asthma, eGPA (a rare blood vessel disease), and GPA (another rare disease). It compares them to healthy volunteers to better understand what causes local inflammation.
GroningenAges 18 years+ - NCT05285839RecruitingPhase 4
Dupixent plus UVB light for moderate to severe eczema
This study tests whether taking Dupixent and receiving narrowband UVB light can improve moderate to severe atopic dermatitis (eczema). It may help people whose symptoms are significant despite usual care.
East Windsor, New JerseyAges 18 years+
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,051 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,083 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.