Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,068 recruiting studies in this area right now.
By phase
- Not applicable3,005
- Phase 21,062
- Phase 1794
- Phase 1/Phase 2441
- Phase 3435
- Phase 4233
- Phase 2/Phase 398
Top conditions
- Multiple Sclerosis330
- Multiple Myeloma328
- Asthma194
- Lymphoma179
- Rheumatoid Arthritis131
- Type 1 Diabetes131
- Atopic Dermatitis123
- Systemic Lupus Erythematosus121
- Acute Lymphoblastic Leukemia118
- HIV Infections106
- Chronic Lymphocytic Leukemia96
- Autoimmune Diseases79
- Follicular Lymphoma70
- Rheumatoid Arthritis (RA)68
- Hodgkin Lymphoma64
- Diabetes Mellitus, Type 163
- Leukemia63
- Type 1 Diabetes Mellitus63
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)97
- Institute of Hematology & Blood Diseases Hospital, China85
- National Cancer Institute (NCI)74
- Assistance Publique - Hôpitaux de Paris65
- AstraZeneca64
- M.D. Anderson Cancer Center58
- Novartis Pharmaceuticals58
- Mayo Clinic50
- City of Hope Medical Center49
- Memorial Sloan Kettering Cancer Center45
Where studies are running
- California498
- Maryland198
- Alabama179
- Florida152
- Arizona150
- Massachusetts118
- New York116
- Texas112
- Illinois82
- Colorado81
Recruiting studies6,068 total
- NCT06908629Recruiting
Helping Detroit cancer survivors with social needs
This study looks at how social needs (like finding enough food) affect cancer survivors in the Detroit area. If you join, researchers will work to connect you with resources that might help.
Detroit, MichiganAges 18 years+ - NCT04221035RecruitingPhase 3
Trial for children with high-risk neuroblastoma testing next steps
This Phase 3 study tests treatment strategies for children with high-risk neuroblastoma, aiming to improve how well the cancer responds and how long patients can stay in control. It compares different intensities and add-ons at key treatment steps depending on your child’s response and health.
Sydney, RandwickAges Up to 21 years - NCT06896916RecruitingPhase 1
Study of etentamig and a CELMoD drug for relapsed multiple myeloma
This trial tests a new combination of two drugs—etentamig given through a vein and a CELMoD pill—for people whose multiple myeloma has come back or stopped responding to treatment. The goal is to see if this combination is safe and helps control the disease.
Beverly Hills, CaliforniaAges 18 years+ - NCT06891898Recruiting
The iLet Experience Study
This study is testing the iLet Bionic Pancreas System in people with type 1 diabetes. It looks at how well the system works in your daily life and asks you to share your glucose data and answer surveys.
Irvine, CaliforniaAges 6 years+ - NCT06899204Recruiting
Abrocitinib for atopic dermatitis after biologic therapy
This study looks at how well abrocitinib (a daily pill) works for people with moderate to severe eczema who have already tried biologic medicines and didn't get enough relief. It aims to see if this treatment can help you better manage your eczema.
San Diego, CaliforniaAges 12 years+ - NCT06897930RecruitingPhase 1/Phase 2
Testing a new drug for adults with lupus
This trial tests an investigational drug called AZD0120 in adults with lupus that hasn't improved with standard treatments. The goal is to see if it's safe and works well for people with lupus-related organ problems.
San Francisco, CaliforniaAges 18–70 - NCT06890884RecruitingPhase 2
Comparing two drug combos for untreated DLBCL
This trial tests a new drug, zilovertamab vedotin, added to standard chemo, compared with another approved drug combo for people with untreated DLBCL (a type of lymphoma). It aims to see which is more effective.
Mobile, AlabamaAges 18 years+ - NCT06892145RecruitingPhase 1
CAR-T cell therapy for tough systemic lupus
This trial tests a new CAR-T cell treatment for adults with systemic lupus erythematosus (SLE) that hasn't improved with standard therapies. It aims to see if targeting CD19 cells can calm the disease.
Hefei, AnhuiAges 18 years+ - NCT05663775RecruitingPhase 2
Mesalamine to prevent bowel inflammation after melanoma immunotherapy
This study tests whether taking mesalamine can prevent colitis (bowel inflammation) in people with advanced melanoma who are treated with ipilimumab plus nivolumab. It may help reduce dangerous stomach or bowel side effects from this cancer treatment.
Edmonton, AlbertaAges 18 years+ - NCT06900010RecruitingPhase 2
CM336 for Autoimmune Blistering Disease
This study tests a new drug called CM336 for people with autoimmune blistering diseases. The drug is designed to calm the immune system and reduce blistering, aiming to improve skin health.
JinanAges 18 years+ - NCT06898905Recruiting
Study of radiation therapy for lymphoma patients getting CAR T or bispecific antibody treatment
This study combines a special schedule of radiation therapy with new cancer treatments (CAR T cells or bispecific antibodies) for adults whose lymphoma has come back or not responded. The radiation is given in small doses twice a day to help the treatment work better.
New Haven, ConnecticutAges 18 years+ - NCT06895538RecruitingPhase 2/Phase 3
Comparing two immune treatments for stem cell transplant patients
This trial compares two drugs, ATLG and ATG, to see which one helps rebuild the immune system better after a stem cell transplant for blood cancer. It aims to improve recovery and reduce complications.
BeijingAges 18 years+ - NCT06896240Recruiting
A smoothie supplement before and after knee revision surgery
This study tests whether drinking a special smoothie each day for 2 weeks before and after your knee revision surgery helps reduce inflammation and improve recovery. It is for people who have health conditions that cause inflammation, like diabetes or heart disease, and who are getting a knee replacement.
New York, New YorkAges 40–80 - NCT06897904Recruiting
Blood and clotting tests in type 1 diabetes kids
This study looks at blood cell counts and clotting function in children with type 1 diabetes. It aims to find any changes that might be related to diabetes, which could help with better monitoring and care.
Asyut, Asyut GovernorateAges Up to 18 years - NCT06892158Recruiting
Massage therapy for sleep in teens with cancer
This trial studies if massage therapy can help teenagers and young adults with cancer sleep better while they are in the hospital. Participants will receive massage sessions and answer questions about their sleep.
Washington D.C., District of ColumbiaAges 12–21 - NCT06894602Recruiting
Can Ultrasound Predict Relapse in Giant Cell Arteritis?
This study uses an ultrasound of the temporal artery (a vessel in your temple) to see if certain findings can predict whether giant cell arteritis will come back. It may help doctors know who needs closer monitoring.
BrestAges 18 years+ - NCT06900244Enrolling by invitation
Metabolic Imaging for MS and Stroke
This study uses a special type of MRI scan to look at how energy is used in the brain. It may help researchers better understand neurological diseases like multiple sclerosis (MS) and stroke.
OxfordAges Up to 99 years - NCT06900829Recruiting
HIV testing program for European hospitals
This trial helps hospitals find undiagnosed HIV by improving testing and care. It supports healthcare teams to identify HIV in people with certain conditions and ensures those diagnosed get connected to treatment.
GhentAges 18 years+ - NCT03910738RecruitingPhase 2
Testosterone treatment for nerve protection and myelin repair in MS
This Phase 2 study tests whether taking testosterone (for low testosterone levels) can help protect nerves and repair myelin in people with relapsing-remitting multiple sclerosis (MS). It may be most relevant if your MS is stable and you have low blood testosterone without current androgen treatment.
BesançonAges 18–55 - NCT05549102Recruiting
CBT therapy study for anxiety and brain circuit changes
This trial studies whether a specific form of talk therapy (CBT) changes brain activity in people with moderate anxiety. It may help your care team understand what works best and how brain “circuits” respond to treatment.
LondonAges 18–64 - NCT05227092Recruiting
MRI scan method test for early spinal lesions in MS
This trial tests a new 3D MRI scan technique to find small, focused spinal cord lesions earlier in people with multiple sclerosis or early MS signs. It may help doctors detect changes sooner, even if lesions are not clearly visible on the first scan.
BordeauxAges 18 years+ - NCT06888973Enrolling by invitationPhase 1/Phase 2
Stem cell infusion for autoimmune diseases
This clinical trial is testing if infusions of special stem cells (called mesenchymal stem cells) can help people with certain autoimmune diseases where standard treatments have not worked well enough. It is an early-phase study in Pakistan for adults (and some children for one condition) with rheumatoid arthritis, lupus, systemic sclerosis, ankylosing spondylitis, or dermatomyositis/polymyositis.
RawalpindiAges 18–50 - NCT06880276RecruitingPhase 3
Studying QLM3003 ointment for mild or moderate eczema
This trial tests if an ointment called QLM3003 is safe and helps adults with mild to moderate atopic dermatitis (eczema). It may be a new treatment option for people whose eczema affects small areas of skin.
ShenyangAges 18–75 - NCT06883526RecruitingPhase 1/Phase 2
ZG005 plus gecacitinib for lymphoma that has returned or not responded
This trial tests a combination of two drugs, ZG005 and gecacitinib, for people with lymphoma that has come back or hasn't gotten better with prior treatment. The goal is to see if this combination can help shrink or control the cancer.
Hangzhou, ZhejiangAges 18 years+
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,068 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,217 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.