Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,230 recruiting studies in this area right now.
By phase
- Not applicable3,147
- Phase 21,063
- Phase 1819
- Phase 1/Phase 2442
- Phase 3425
- Phase 4238
- Phase 2/Phase 396
Top conditions
- Multiple Sclerosis343
- Multiple Myeloma332
- Asthma194
- Lymphoma182
- Rheumatoid Arthritis140
- Type 1 Diabetes133
- Atopic Dermatitis129
- Systemic Lupus Erythematosus125
- Acute Lymphoblastic Leukemia122
- HIV Infections116
- Chronic Lymphocytic Leukemia100
- Autoimmune Diseases81
- Follicular Lymphoma74
- Diabetes Mellitus, Type 169
- Hodgkin Lymphoma67
- Rheumatoid Arthritis (RA)66
- Leukemia64
- Type 1 Diabetes Mellitus63
Leading sponsors
- Institute of Hematology & Blood Diseases Hospital, China91
- National Institute of Allergy and Infectious Diseases (NIAID)90
- National Cancer Institute (NCI)73
- Assistance Publique - Hôpitaux de Paris70
- M.D. Anderson Cancer Center63
- Novartis Pharmaceuticals60
- AstraZeneca57
- City of Hope Medical Center47
- Mayo Clinic46
- Memorial Sloan Kettering Cancer Center44
Where studies are running
- California491
- Maryland195
- Alabama175
- Florida144
- Arizona142
- New York123
- Massachusetts119
- Texas118
- Illinois81
- Colorado77
Recruiting studies6,230 total
- NCT06466135RecruitingPhase 2
Study of WAL0921 for glomerular kidney diseases
This study tests a new drug called WAL0921 for people with certain types of kidney disease. The goal is to see if it can help protect kidney function.
Los Angeles, CaliforniaAges 18–75 - NCT06466889Recruiting
Mastocytosis Registry of Zurich
This study is a registry (a simple data collection) for people with mastocytosis or hypertryptasemia who are treated at the University Hospital of Zurich. It aims to gather information to better understand these conditions and improve care.
ZurichAges Any age - NCT06467994RecruitingPhase 2
Boiled cashew nut therapy for children with cashew allergy
This trial tests whether a specially boiled cashew nut can help children with cashew allergy eat cashews without a reaction. It is for children ages 2 to 17 with a confirmed cashew allergy, and it avoids other serious health conditions.
Hong KongAges 2–17 - NCT06468267RecruitingPhase 2
Lower-intensity transplant with thiotepa combo for relapsed T-cell lymphoma
This study tests a stronger but safer chemo preparation before a stem cell transplant for people with T-cell lymphoma that has returned or not responded to treatment.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT06468709RecruitingPhase 4
Preventing recurrence of high-risk type 1 AIP
This trial studies a treatment to prevent recurrence in people with type 1 autoimmune pancreatitis (AIP) who are at high risk. It looks at how well the treatment works and whether it can keep the disease from coming back.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06469593Recruiting
Automated insulin delivery for type 1 diabetes study
This study tests a new automated insulin delivery (AID) system that connects your insulin pump to your glucose monitor to help keep your blood sugar in range. It is for both children and adults with type 1 diabetes who have not used an AID system before.
Herlev, Greater CopenhagenAges 7 years+ - NCT06469788Recruiting
COVID-19 vaccine navigation for rheumatology patients
This study looks at helping Black and Latinx adults with autoimmune rheumatic diseases get the updated COVID-19 vaccine. It offers information and support (like testimonials and navigation help) to see what works best.
Birmingham, AlabamaAges 18 years+ - NCT06470295RecruitingEarly Phase 1
C-peptide's effect on low blood sugar response
This study tests whether C-peptide (a substance made by the pancreas) can help your body respond better to low blood sugar (hypoglycemia). It's a very early trial for people without certain health conditions.
Cincinnati, OhioAges 18–40 - NCT06471296Recruiting
How viruses affect tumors and treatment
This study looks at how viruses change the environment around tumors, especially in cancers of the throat, lung, lymph nodes, and anal canal. It aims to understand why some treatments work better for virus-related cancers than others.
ParisAges 18–100 - NCT06472206Recruiting
HIV support with a health coach and smartphone app
This study is testing a program that pairs you with a community health worker and a smartphone app to help get your HIV under control. It is for people whose virus is not fully suppressed and who live in certain Southern states.
Hobson City, AlabamaAges 18 years+ - NCT06472596Recruiting
Asthma and Kidney Disease Risk in Children
This study looks at whether children with asthma might have a higher risk of developing kidney problems later. It involves checking medical records and lab tests to see if asthma is linked to chronic kidney disease.
SohagAges 2–18 - NCT06474182Recruiting
Apixaban for blood clots in myeloma patients
This study looks at how Apixaban (a blood thinner) works in people with newly diagnosed multiple myeloma. It compares them to people having knee replacement surgery. The goal is to see if the drug prevents clots effectively in both groups.
Saint-EtienneAges 18 years+ - NCT06474169Recruiting
T-cell study in long-term kidney failure
This study is looking at how immune cells called T-cells work in people with long-term kidney failure. It tests whether these cells can be changed in the lab to help treat the condition.
OrléansAges 18 years+ - NCT06474520Recruiting
Bovine gallstone extract for inflammatory brain disease
This trial tests a natural substance called Calculus Bovis Sativus (CBS) to see if it helps people with certain inflammatory brain conditions like multiple sclerosis, neuromyelitis optica, MOGAD, or ADEM. The goal is to find out if it is safe and effective.
Wuhan, HubeiAges 18 years+ - NCT06474546Recruiting
Diet intervention feasibility study for juvenile arthritis
This trial tests whether a special diet can help children and teens with juvenile arthritis. If you join, you will follow the diet and provide stool samples so the researchers can see how it affects your gut and arthritis.
Winnipeg, ManitobaAges 8–18 - NCT06474598RecruitingPhase 2
Test of MTX228 for type 1 diabetes with some insulin
This study tests a new medication, MTX228, to see if it can help people with type 1 diabetes who still make some insulin. It may slow the loss of your own insulin production and improve blood sugar control.
Edmonton, AlbertaAges 18–65 - NCT06475235RecruitingPhase 1
Pembrolizumab with chemo for new CNS lymphoma
This trial tests a combination of the immunotherapy drug pembrolizumab (Keytruda) with standard chemotherapy for people newly diagnosed with primary CNS lymphoma. The goal is to see if adding pembrolizumab can improve outcomes compared to chemotherapy alone.
Boston, MassachusettsAges 18 years+ - NCT06475469Recruiting
Immune system in untreated CLL and infection risk
This study looks at how the immune system works in people with untreated CLL and tries to find ways to predict who might get infections. It aims to help doctors better protect patients from infections in the future.
ReimsAges 18 years+ - NCT06477549RecruitingPhase 2
Comparing Two Drug Combinations for Stem Cell Transplant
This study compares two different drug combinations (BeFluBu and FluBuRux) used before a stem cell transplant from a half-matched (haploidentical) donor. The goal is to see which combination works better to prepare your body for the transplant and control your blood cancer.
Saint PetersburgAges 18–75 - NCT06477783Recruiting
Study of teclistamab for relapsed/refractory multiple myeloma
This study tests how well teclistamab works for people with multiple myeloma that has come back or not responded to at least three prior treatments. You may be eligible if you are starting teclistamab as part of your regular care.
Bonheiden, AntwerpenAges 18 years+ - NCT06478381RecruitingPhase 1
L218CAR19 for relapsed or refractory B-cell lymphoma
This trial tests a new type of CAR-T cell therapy (called L218CAR19) for people with B-cell lymphoma that has come back or not responded to at least two prior treatments. The goal is to see if this therapy can help shrink or control the lymphoma.
Zhengzhou, HenanAges 18–75 - NCT06478537RecruitingPhase 2
Hetrombopag for Immune Tolerance in ITP After Platelet Recovery
This study tests whether a drug called hetrombopag can help your immune system stop attacking your platelets, so your platelet count stays up even after stopping the drug. It's for people with ITP who responded well to hetrombopag but want to see if they can stay in remission without it.
Beijing, Beijing MunicipalityAges 18–50 - NCT06478472Recruiting
Orelabrutinib plus rituximab for marginal zone lymphoma
This trial tests a combination of two targeted therapies—oralebrutinib (a pill that blocks a protein in cancer cells) and rituximab (an antibody infusion)—for people with marginal zone lymphoma that has returned or cannot be treated with local therapies. The goal is to see if this combo works well and is safe.
Xiamen, FujianAges 18 years+ - NCT06478784Recruiting
Strength training for multiple sclerosis: a randomized trial
This study tests whether a strength-training program (like lifting weights or using resistance bands) can help people with multiple sclerosis feel better and move better. It is for people who can walk on their own and have been stable (no recent relapses).
ValladolidAges 18 years+
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,230 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,763 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.