Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,068 recruiting studies in this area right now.
By phase
- Not applicable3,005
- Phase 21,062
- Phase 1794
- Phase 1/Phase 2441
- Phase 3435
- Phase 4233
- Phase 2/Phase 398
Top conditions
- Multiple Sclerosis330
- Multiple Myeloma328
- Asthma194
- Lymphoma179
- Rheumatoid Arthritis131
- Type 1 Diabetes131
- Atopic Dermatitis123
- Systemic Lupus Erythematosus121
- Acute Lymphoblastic Leukemia118
- HIV Infections106
- Chronic Lymphocytic Leukemia96
- Autoimmune Diseases79
- Follicular Lymphoma70
- Rheumatoid Arthritis (RA)68
- Hodgkin Lymphoma64
- Diabetes Mellitus, Type 163
- Leukemia63
- Type 1 Diabetes Mellitus63
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)97
- Institute of Hematology & Blood Diseases Hospital, China85
- National Cancer Institute (NCI)74
- Assistance Publique - Hôpitaux de Paris65
- AstraZeneca64
- M.D. Anderson Cancer Center58
- Novartis Pharmaceuticals58
- Mayo Clinic50
- City of Hope Medical Center49
- Memorial Sloan Kettering Cancer Center45
Where studies are running
- California498
- Maryland198
- Alabama179
- Florida152
- Arizona150
- Massachusetts118
- New York116
- Texas112
- Illinois82
- Colorado81
Recruiting studies6,068 total
- NCT06880276RecruitingPhase 3
Studying QLM3003 ointment for mild or moderate eczema
This trial tests if an ointment called QLM3003 is safe and helps adults with mild to moderate atopic dermatitis (eczema). It may be a new treatment option for people whose eczema affects small areas of skin.
ShenyangAges 18–75 - NCT04372615RecruitingPhase 2
Inebilizumab for NMDA receptor encephalitis after initial steroids
This Phase 2 study tests inebilizumab in people with NMDA receptor encephalitis, an immune-related brain condition. It looks to see if adding this treatment after starting steroids (and possibly other first treatments) improves recovery and safety.
Birmingham, AlabamaAges 12 years+ - NCT03928431Recruiting
Restore gut bacteria in newborns using special microbiome samples
This study looks at whether restoring a newborn’s gut bacteria (microbiome) can improve early health. Babies are treated based on the birth conditions, especially whether delivery was vaginal or by C-section.
Stockholm, Stockholm CountyAges 5 minutes–15 minutes - NCT06883097Recruiting
Quitting smoking with HIV: A smoking cessation trial
This study tests whether nicotine replacement therapy (like patches or gum) can help people living with HIV quit smoking. You'll be part of a program that supports your quit attempt while you receive care for HIV.
Winston-Salem, North CarolinaAges 18 years+ - NCT06885957Recruiting
Monoclonal antibodies for AQP4-positive NMOSD
This trial is testing monoclonal antibody treatments for people with a specific type of neuromyelitis optica spectrum disorder (NMOSD) caused by AQP4 antibodies. It aims to see if these targeted therapies can help control the disease and prevent relapses.
Wuhan, HubeiAges 18–65 - NCT06880653Recruiting
Exercise dose study for arthritis pain
This study looks at how different amounts of exercise affect arthritis symptoms. If you have arthritis or a related condition, you may be asked to try a specific weekly exercise goal to see if it helps your pain and mobility.
Columbia, South CarolinaAges 18 years+ - NCT06887322Enrolling by invitationPhase 1/Phase 2
Herbal cream for plaque psoriasis
This study tests an herbal cream made from Ciplukan (a plant) on plaque psoriasis. If you are an adult with mild-to-moderate psoriasis and are not already using other treatments, this trial may help find a gentler option.
Bandung, West JavaAges 18–60 - NCT06880705Recruiting
Trans-Led Care Study for alcohol and drug support
This study is testing a program designed by and for transgender adults to help with alcohol or drug use problems. It looks at whether a supportive, community-based approach can improve health and well-being.
Chicago, IllinoisAges 18 years+ - NCT06887283Recruiting
Essen Amyloidosis Registry Study
This study collects information from people with suspected or confirmed amyloidosis. The goal is to learn more about the condition and improve patient care.
Essen, North Rhine-WestphaliaAges 18 years+ - NCT06883344Recruiting
Automated insulin for managing blood sugar during labor
This study tests if an automated insulin delivery system can help manage blood sugar levels during labor and delivery in pregnant women with type 1 diabetes. If successful, it could make the process safer and easier.
Los Angeles, CaliforniaAges 18–55 - NCT06880835Recruiting
Inhaled insulin vs injected insulin for exercise blood sugar drops in type 1 diabetes
This trial tests whether a new inhaled insulin (Technosphere) causes fewer low blood sugar episodes during exercise compared to standard injected insulin in people with type 1 diabetes who use an automated insulin pump. It may help you avoid hypoglycemia while staying active.
Louisville, KentuckyAges 18–65 - NCT06889168RecruitingPhase 1
Long-term safety of imatinib for LAM
This study tests the long-term safety and tolerability of the drug imatinib in women with LAM, a rare lung disease that causes cysts. It may help stabilize lung function over time.
New York, New YorkAges 18–64 - NCT06880419RecruitingPhase 2
Anti-CD25 antibody to prevent graft-versus-host disease in high-risk adults
This trial tests whether an antibody called anti-CD25 can help prevent a serious side effect (graft-versus-host disease) in adults getting a stem cell transplant for blood disorders. It is for people considered high-risk based on a special scoring model.
Tianjin, Tianjin MunicipalityAges 16 years+ - NCT06880913RecruitingPhase 1/Phase 2
Dual CAR-T therapy for relapsed B-cell acute lymphoblastic leukemia
This trial tests a new type of CAR-T cell therapy that targets two markers (CD19 and CD22) on leukemia cells. It's for people whose B-cell acute lymphoblastic leukemia has come back or hasn't responded to other treatments.
Beijing, Beijing MunicipalityAges 12–65 - NCT06882057RecruitingPhase 2/Phase 3
Treatment for newly diagnosed low-risk pediatric B-ALL
This trial tests a treatment plan for children newly diagnosed with low-risk B-cell ALL. It aims to improve outcomes while reducing side effects.
Hefei, AnhuiAges 1–18 - NCT06880393RecruitingPhase 2
BCMA CAR-T for high-risk multiple myeloma
This trial tests a new immunotherapy called BCMA CAR-T for people with multiple myeloma that is considered high-risk. It aims to see if this treatment can help patients who had a short response to initial therapy or have specific genetic changes in their cancer.
TianjinAges 18–75 - NCT06881654Enrolling by invitation
Teeth whitening with a softer tray vs. a rigid tray
This trial compares two types of trays used for at-home teeth whitening with a 16% carbamide peroxide gel: a soft tray versus a rigid tray. The goal is to see if one works better and feels more comfortable.
Alcorcón, MadridAges 18 years+ - NCT06889948RecruitingPhase 2
Daratumumab for kidney disease caused by abnormal proteins
This trial tests if daratumumab can help people with a kidney condition called MGRS, where abnormal proteins damage the kidneys. The goal is to see if the drug can reduce protein in the urine and protect kidney function.
HelsinkiAges 18 years+ - NCT06881290RecruitingPhase 1
Vunakizumab for mild to moderate lupus
This trial tests a new drug called Vunakizumab for people with mild to moderate lupus that affects the skin or joints. It aims to see if adding this drug to your current treatment can help control symptoms better.
Beijing, Beijing MunicipalityAges 18–65 - NCT06886971Recruiting
Strategies to help youth with HIV stay virally suppressed
This trial tests a strategy to help young people with HIV keep their virus levels low. It focuses on using a long-acting injectable medication combination (Cabotegravir and Rilpivirine) and requires communication with your HIV doctor.
Baltimore, MarylandAges 12–30 - NCT06887062RecruitingPhase 2
Testing dapagliflozin and bosentan for large vessel vasculitis
This trial tests two drugs, dapagliflozin and bosentan, to see if they help people with large vessel vasculitis who have been in remission for at least 6 months. The goal is to prevent flares and improve blood vessel health.
EdinburghAges 18 years+ - NCT00097292Recruiting
Preventing Type 1 Diabetes in At-Risk People
This study looks for people at high risk of developing type 1 diabetes (based on family history or blood markers) and follows them over time to understand disease development. The goal is to eventually prevent or delay type 1 diabetes in people who don't have it yet.
Orange, CaliforniaAges 2–45 - NCT06876506Recruiting
How B-cells relate to common allergies
This study looks at a type of immune cell (B regulatory cell) in the blood of people with and without allergies to pollens, house dust mites, or insect stings. It aims to help understand how these cells work in allergic disease.
Hull, East YorkshireAges 18 years+ - NCT06878872Recruiting
Healthier lifestyles for teens with type 1 diabetes
This study helps teens with type 1 diabetes and their parents make healthier lifestyle changes. If your teen is above a certain weight range and has had diabetes for at least 6 months, they may be able to join.
Providence, Rhode IslandAges 13–18
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,068 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,217 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.