Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,230 recruiting studies in this area right now.
By phase
- Not applicable3,147
- Phase 21,063
- Phase 1819
- Phase 1/Phase 2442
- Phase 3425
- Phase 4238
- Phase 2/Phase 396
Top conditions
- Multiple Sclerosis343
- Multiple Myeloma332
- Asthma194
- Lymphoma182
- Rheumatoid Arthritis140
- Type 1 Diabetes133
- Atopic Dermatitis129
- Systemic Lupus Erythematosus125
- Acute Lymphoblastic Leukemia122
- HIV Infections116
- Chronic Lymphocytic Leukemia100
- Autoimmune Diseases81
- Follicular Lymphoma74
- Diabetes Mellitus, Type 169
- Hodgkin Lymphoma67
- Rheumatoid Arthritis (RA)66
- Leukemia64
- Type 1 Diabetes Mellitus63
Leading sponsors
- Institute of Hematology & Blood Diseases Hospital, China91
- National Institute of Allergy and Infectious Diseases (NIAID)90
- National Cancer Institute (NCI)73
- Assistance Publique - Hôpitaux de Paris70
- M.D. Anderson Cancer Center63
- Novartis Pharmaceuticals60
- AstraZeneca57
- City of Hope Medical Center47
- Mayo Clinic46
- Memorial Sloan Kettering Cancer Center44
Where studies are running
- California491
- Maryland195
- Alabama175
- Florida144
- Arizona142
- New York123
- Massachusetts119
- Texas118
- Illinois81
- Colorado77
Recruiting studies6,230 total
- NCT07138898RecruitingPhase 2
Managing immune medications for shoulder replacement in rheumatology patients
This trial tests two ways of managing your immunosuppressant medication around the time of shoulder replacement surgery. The goal is to see if one approach leads to fewer infections while still controlling your rheumatic disease.
New York, New YorkAges 18 years+ - NCT07048795Recruiting
Testing mylife CamAPS FX system in type 1 diabetes patients in France
This study tests a new automated insulin delivery system (mylife CamAPS FX) for people with type 1 diabetes. It aims to see how well the system works when paired with a Dexcom G6 continuous glucose monitor.
AmiensAges Any age - NCT03192267Recruiting
Study of lung changes in early rheumatoid arthritis
This study looks at lung health in people with early rheumatoid arthritis (RA). It may help doctors understand how RA affects the lungs soon after diagnosis and guide better care.
Omaha, NebraskaAges 19–90 - NCT06486116Recruiting
Home exercise program for people with multiple sclerosis
This trial tests a home exercise program designed for people with multiple sclerosis. It aims to improve walking and daily function through simple, task-specific exercises you can do at home.
Brooklyn, New YorkAges 18–65 - NCT06487247Recruiting
Home transfusion program for blood cancer patients
This trial offers red blood cell or platelet transfusions at home for people with blood cancer who are no longer responding to treatment. It aims to improve comfort and quality of life by avoiding hospital visits.
Boston, MassachusettsAges 18 years+ - NCT06487624RecruitingPhase 1
Study of HCB301 for advanced solid tumors and Hodgkin lymphoma
This trial tests a new drug called HCB301, which targets proteins that help cancer hide from the immune system. It is for people with advanced solid tumors or classical Hodgkin lymphoma who have tried other treatments without success.
Greenville, South CarolinaAges 18 years+ - NCT06488118Recruiting
Lung response to inhaled immune stimulant in healthy and asthma
This study tests how the lungs react to breathing in a weak immune-stimulating drug (R848). It includes healthy volunteers and people with mild to moderate asthma to see differences in airway responses.
Cambridge, CambridgeshireAges 18–60 - NCT06488742Recruiting
Kanuka oil vs. hydrocortisone for eczema
This trial tests if a cream made from kanuka oil works better than a mild steroid cream (hydrocortisone) to treat eczema. It looks at how much the itching and skin rash improve.
Boynton Beach, FloridaAges 12–75 - NCT06491238Recruiting
Light vs. moderate exercise for myasthenia gravis
This study compares light exercise (like gentle walking) to moderate exercise (like brisk walking) for people with myasthenia gravis. It aims to see if one type of exercise is safer and more helpful for managing symptoms.
Saint Paul, MinnesotaAges 18–80 - NCT06491602Recruiting
Lupus nephritis in children at Sohag Hospital
This study looks at children with lupus nephritis (a kidney problem caused by lupus) to understand what factors affect their disease and outcomes. It may help doctors better treat kids with this condition.
SohagAges 1 month–18 years - NCT06492200Recruiting
High-Fiber Diet for Rheumatoid Arthritis
This study tests whether eating more high-fiber foods can improve rheumatoid arthritis symptoms by changing the bacteria in your gut. You would follow a special diet and have your disease activity monitored.
WürzburgAges 18–99 - NCT06492837RecruitingPhase 2
Study of mosunetuzumab and zanubrutinib for relapsed follicular lymphoma
This trial tests a combination of two targeted drugs, mosunetuzumab and zanubrutinib, for people with follicular lymphoma that has come back or not responded to prior treatment. The goal is to see if this combination is safe and effective.
AdelaideAges 18 years+ - NCT06494228Recruiting
Comparing MRI scans for optic neuritis
This study compares three types of brain MRI scans (3D FLAIR, DIR, and PSIR) to see which is best at detecting optic neuritis (inflammation of the optic nerve). It looks at scans from patients with multiple sclerosis or NMO spectrum disorder to improve diagnosis.
Strasbourg, Les Hôpitaux Universitaires de StrasbourgAges 18 years+ - NCT06494371RecruitingPhase 1
Study of LCAR-HL30 for Hodgkin's and anaplastic large cell lymphoma
This trial tests a new treatment called LCAR-HL30 for people with Hodgkin's lymphoma or anaplastic large cell lymphoma that has come back or not responded to therapy. The treatment targets cells with a protein called CD30 to help your body fight the cancer.
ShanghaiAges 18–75 - NCT06495138Recruiting
Eye exercises for dizziness in multiple sclerosis
This study tests a new type of eye exercise to help with dizziness and balance problems in people with multiple sclerosis (MS). The exercise involves moving your head and eyes in a specific way to retrain your balance system.
Atlanta, GeorgiaAges 18–89 - NCT06495190Recruiting
Blueberries, exercise, and memory in older adults
This study tests whether eating blueberries and doing regular exercise can help with mild memory decline. You will be assigned to one of four groups (blueberries + walking, blueberries + stretching, or similar combos) for 12 weeks.
Kannapolis, North CarolinaAges 65–85 - NCT06496308RecruitingPhase 3
Adding orelabrutinib to standard therapy for mantle cell lymphoma
This trial tests adding the targeted therapy orelabrutinib (a BTK inhibitor) to standard chemotherapy (bendamustine) and immunotherapy (rituximab) for people with high-risk mantle cell lymphoma who have not had treatment before. The goal is to see if the combination works better at controlling the cancer.
ShanghaiAges 18–80 - NCT06496412Recruiting
Fecal transplant for brain health in type 1 diabetes
This trial tests whether transplanting healthy bacteria into your gut can improve memory and thinking skills in people with long-term type 1 diabetes. If you have had type 1 diabetes for 10 years or more, this study may help find a new way to protect your brain.
Changsha, HunanAges 18–60 - NCT06497361RecruitingEarly Phase 1
PRG-2311 for hard-to-treat lupus nephritis and IgG4 disease
This trial tests a new treatment called PRG-2311 for people with lupus nephritis or IgG4-related disease that has not responded to standard therapies. The treatment uses a type of immune cell therapy (CAR-T) to try to control the disease.
Wuhan, HubeiAges 18 years+ - NCT06497452Recruiting
Glofitamab with rescue therapy for relapsed B-cell lymphoma
This study is testing how well the drug Glofitamab works when given along with standard rescue treatments for adults with B-cell Non-Hodgkin Lymphoma that has relapsed or not responded to prior therapy. The goal is to see if this combination is effective and safe in everyday medical practice.
Suzhou, JiangsuAges 18 years+ - NCT06497387RecruitingEarly Phase 1
PRG-1801 for stubborn lupus kidney and IgG4 disease
This trial tests a new treatment called PRG-1801 for people with lupus nephritis (kidney inflammation from lupus) or IgG4-related disease that has not improved with standard treatments. The treatment uses your own immune cells to target and calm the disease.
Wuhan, HubeiAges 18 years+ - NCT06497738Recruiting
Comparing two drug combos for elderly myeloma
This trial compares two different drug combinations (DRd and VRd-lite) for older adults (65+) who are newly diagnosed with multiple myeloma. The goal is to see which combination works better and is easier to tolerate.
Changzhou, JiangsuAges 65 years+ - NCT06497829Recruiting
Geranylgeraniol for MVK deficiency trial
This study tests whether a natural supplement called geranylgeraniol can help people with mevalonate kinase deficiency (a rare metabolic condition). If you are 12 or older and have this diagnosis, you may be able to join.
PragueAges 12 years+ - NCT06498167Recruiting
Rinvoq safety study
This study is checking the safety of the medicine Rinvoq (upadacitinib) in people who have been prescribed it. It involves answering a few questions over the phone to help doctors understand how the medicine is working for you.
PortoAges 18 years+
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,230 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,763 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.