Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,068 recruiting studies in this area right now.
By phase
- Not applicable3,005
- Phase 21,062
- Phase 1794
- Phase 1/Phase 2441
- Phase 3435
- Phase 4233
- Phase 2/Phase 398
Top conditions
- Multiple Sclerosis330
- Multiple Myeloma328
- Asthma194
- Lymphoma179
- Rheumatoid Arthritis131
- Type 1 Diabetes131
- Atopic Dermatitis123
- Systemic Lupus Erythematosus121
- Acute Lymphoblastic Leukemia118
- HIV Infections106
- Chronic Lymphocytic Leukemia96
- Autoimmune Diseases79
- Follicular Lymphoma70
- Rheumatoid Arthritis (RA)68
- Hodgkin Lymphoma64
- Diabetes Mellitus, Type 163
- Leukemia63
- Type 1 Diabetes Mellitus63
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)97
- Institute of Hematology & Blood Diseases Hospital, China85
- National Cancer Institute (NCI)74
- Assistance Publique - Hôpitaux de Paris65
- AstraZeneca64
- M.D. Anderson Cancer Center58
- Novartis Pharmaceuticals58
- Mayo Clinic50
- City of Hope Medical Center49
- Memorial Sloan Kettering Cancer Center45
Where studies are running
- California498
- Maryland198
- Alabama179
- Florida152
- Arizona150
- Massachusetts118
- New York116
- Texas112
- Illinois82
- Colorado81
Recruiting studies6,068 total
- NCT06871176Recruiting
New PET/MR scan vs standard imaging for multiple myeloma
This trial compares a new type of PET/MR scan (using a radioactive tracer called Ga-68 PentixaFor) with standard imaging to see if it can better detect multiple myeloma at diagnosis and during follow-up. It may help improve staging and treatment planning.
Toronto, OntarioAges 18 years+ - NCT06868641Recruiting
Study for people stopping long-acting injectable PrEP
This study follows people who are stopping long-acting injectable PrEP (cabotegravir or lenacapavir). It checks how long the drug stays in your body and helps make sure you stay protected during that time. You'll do monthly video visits, mail in blood samples, and fill out short surveys.
New York, New YorkAges 18 years+ - NCT06876467Recruiting
Study of immune response to hepatitis B vaccine
This study looks at how your body's cells respond after getting a hepatitis B vaccine. It may help researchers understand how well the vaccine works.
ParisAges 18 years+ - NCT06872996Recruiting
Do food prick test results change over time?
This study checks whether the shelf life of food extracts used in skin prick tests affects how consistent the results are. It may help make food allergy testing more reliable for people like you.
OrléansAges 18 years+ - NCT06878872Recruiting
Healthier lifestyles for teens with type 1 diabetes
This study helps teens with type 1 diabetes and their parents make healthier lifestyle changes. If your teen is above a certain weight range and has had diabetes for at least 6 months, they may be able to join.
Providence, Rhode IslandAges 13–18 - NCT06879340RecruitingPhase 1
Testing a new CAR-T therapy for B-cell blood cancers
This study tests a new CAR-T cell therapy called DuoCAR20.19.22-D95 for people with certain blood cancers (like lymphoma and ALL) that have come back or haven't responded to multiple treatments. It aims to see if this therapy is safe and can help shrink or control the cancer.
Westwood, KansasAges 18 years+ - NCT06874764Enrolling by invitation
Training with a wireless system for thinking and reaction in MS
This study tests whether a special wireless reaction training system can help improve thinking and reaction speed in people with multiple sclerosis (MS). It compares this training to standard exercises to see which works better for your brain health.
Izmir, BornovaAges 18–55 - NCT06870045Recruiting
Walking ability test in children with JIA
This study looks at how well children with JIA (arthritis in one knee) can walk and balance, using a simple test called the Dynamic Gait Index. It aims to find a better way to measure walking problems in kids with JIA.
Istanbul, TurkeyAges 8–16 - NCT06873464Enrolling by invitation
Brain stimulation to reduce fatigue in multiple sclerosis
This trial tests if a gentle brain stimulation technique (tDCS) can help reduce fatigue and improve quality of life for people with multiple sclerosis. You would receive either real or placebo stimulation over several sessions to see if it helps you feel less tired.
MadridAges 18–75 - NCT06870760Recruiting
Early blood cancer detection in Charlotte firefighters
This study looks at firefighters to find early signs of blood cancers before they become serious. It aims to learn how to catch these cancers earlier, so they can be treated sooner.
Charlotte, North CarolinaAges 40–49 - NCT06879444Enrolling by invitation
Core strength and pelvic floor in Sjogren's
This study looks at how core stability and pelvic floor muscles work in people with primary Sjogren's syndrome. If you have this condition, the results may help doctors understand changes in muscle function.
Denizli, DenizliAges 18–65 - NCT06877403Enrolling by invitation
Fatigue study in myasthenia gravis patients
This study looks at how common and how severe fatigue is in people with myasthenia gravis. It aims to understand the impact of fatigue on daily life and may help improve care for patients with this condition.
Clermont-FerrandAges 18 years+ - NCT06876064Recruiting
Tracking people at risk for rheumatoid arthritis
This study follows different groups of people—from those at high risk of developing rheumatoid arthritis to those recently diagnosed—to learn more about the disease. By joining, you help researchers understand who gets RA and why, which may lead to earlier detection and better care.
Montpellier, HéraultAges 18–80 - NCT06875063RecruitingPhase 1
CAR-T cell therapy for CD19-positive relapsed B-cell lymphoma
This trial tests a new CAR-T cell therapy (a type of immune cell treatment) for patients with a specific kind of B-cell lymphoma that has come back or not responded to previous therapy. The treatment targets a protein called CD19 on the cancer cells to help your immune system fight the lymphoma.
Xiamen, FujianAges 18–70 - NCT06874946RecruitingPhase 1/Phase 2
Nanobody-based CAR-T cells for relapsed T-cell leukemia or lymphoma
This trial tests a new treatment using your own immune cells (called CAR-T cells) that are reprogrammed to find and destroy T-cell leukemia or lymphoma cells that have the CD5 protein. It may be an option if your cancer has come back or hasn't responded to other treatments.
Beijing, Beijing MunicipalityAges 3–70 - NCT06876649RecruitingPhase 4
Long-term safety study of Pirtobrutinib
This trial is for people who are already in a Lilly study taking pirtobrutinib. It looks at the long-term safety of the drug by continuing to monitor you.
Jacksonville, FloridaAges 18 years+ - NCT06869551RecruitingPhase 3
Testing a New Drug for Juvenile Psoriatic Arthritis
This study tests an investigational drug called Deucravacitinib to see if it can safely and effectively treat Juvenile Psoriatic Arthritis in children. You may be able to join if standard treatments haven't helped enough.
Lancaster, CaliforniaAges 5–17 - NCT06876662RecruitingPhase 4
Continuing pirtobrutinib for CLL and lymphoma patients
This trial continues to give pirtobrutinib to people with chronic lymphocytic leukemia or certain other lymphomas who were already in a previous study with this drug. It helps researchers keep track of long-term safety and how well the drug works over time.
Miami, FloridaAges 18 years+ - NCT06877923Recruiting
Elemental 028 extra nutritional support study
This study is testing a special liquid food called Elemental 028 Extra for people who need at least 30% of their nutrition from an elemental formula. It aims to see how well it works and how people tolerate it.
TrowbridgeAges 3 years+ - NCT06875960RecruitingPhase 4
Continuing deucravacitinib for people with lupus
This study lets people who have already finished a previous trial of deucravacitinib continue taking the medicine. It is for adults with lupus, including skin-only forms of the disease, to see if long-term treatment remains safe and helpful.
Farmington, ConnecticutAges 18–75 - NCT06860594RecruitingPhase 1
Triapine plus radiation for recurrent brain tumors
This trial tests whether adding an experimental drug called triapine to a second round of radiation therapy can help treat brain tumors that have come back after initial treatment. It may be a good option for people with recurrent glioblastoma or astrocytoma who meet safety criteria.
Duarte, CaliforniaAges 18 years+ - NCT06859424RecruitingPhase 2
Testing a new GVHD prevention method after donor stem cell transplant
This trial tests a new way to prevent graft-versus-host disease (a common side effect of stem cell transplant) using a drug called cyclophosphamide after transplant. It is for adults with certain blood cancers who need a transplant from a partially matched unrelated donor.
Birmingham, AlabamaAges 18–66 - NCT06863974Recruiting
Finding markers of relapsing nerve inflammation in children
This study looks at children who have had a first attack of nerve inflammation (like ADEM, vision loss, or spinal cord issues) to find markers in the blood that might show if it will come back. It tests blood and cells to better understand the immune response.
AngersAges 18 years+ - NCT06858319RecruitingPhase 3
Long-term study of zigakibart for IgA nephropathy
This study is for people with IgA nephropathy who completed a previous zigakibart study. It tests whether continuing treatment with zigakibart (given as a shot every two weeks) is safe and helpful over a longer period.
Denver, ColoradoAges 18–100
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,068 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,217 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.