Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,236 recruiting studies in this area right now.
By phase
- Not applicable3,144
- Phase 21,066
- Phase 1823
- Phase 1/Phase 2446
- Phase 3426
- Phase 4238
- Phase 2/Phase 393
Top conditions
- Multiple Sclerosis345
- Multiple Myeloma334
- Asthma194
- Lymphoma183
- Rheumatoid Arthritis141
- Type 1 Diabetes131
- Atopic Dermatitis129
- Systemic Lupus Erythematosus126
- Acute Lymphoblastic Leukemia123
- HIV Infections117
- Chronic Lymphocytic Leukemia100
- Autoimmune Diseases81
- Follicular Lymphoma74
- Diabetes Mellitus, Type 170
- Hodgkin Lymphoma67
- Leukemia64
- Rheumatoid Arthritis (RA)64
- Mantle Cell Lymphoma62
Leading sponsors
- Institute of Hematology & Blood Diseases Hospital, China91
- National Institute of Allergy and Infectious Diseases (NIAID)91
- National Cancer Institute (NCI)74
- Assistance Publique - Hôpitaux de Paris70
- Novartis Pharmaceuticals65
- M.D. Anderson Cancer Center63
- AstraZeneca57
- City of Hope Medical Center46
- Mayo Clinic46
- Memorial Sloan Kettering Cancer Center45
Where studies are running
- California492
- Maryland196
- Alabama179
- Arizona141
- Florida141
- New York122
- Massachusetts120
- Texas119
- Illinois82
- Colorado77
Recruiting studies6,236 total
- NCT07111637Recruiting
AI-assisted MRI for multiple sclerosis care
This trial is testing whether an artificial intelligence tool can improve the quality of MRI scans for people with MS. It aims to make scans faster, better, and more equitable for everyone in the NHS.
LondonAges 18–99 - NCT07595367RecruitingPhase 2
BBD-1 immune therapy for IgA vasculitis
This trial tests a new drug called BBD-1 that may help treat IgA vasculitis, a condition where your immune system attacks small blood vessels, causing a purple rash and organ damage. The study measures how well BBD-1 reduces symptoms and side effects.
Baltimore, MarylandAges Any age - NCT06651177RecruitingPhase 2
Tirzepatide with buprenorphine for opioid use disorder
This study tests whether adding tirzepatide, a medication used for weight and blood sugar, to buprenorphine treatment helps people with opioid use disorder. It aims to see if the combination improves outcomes compared to buprenorphine alone.
Jacksonville, FloridaAges 18 years+ - NCT02015013RecruitingPhase 2
Blood cell collection study for immune system disorders
This study collects blood-forming cells from people with low CD4 counts and healthy volunteers to learn how the immune system works. It may help researchers better understand and treat conditions like idiopathic CD4 lymphocytopenia.
Bethesda, MarylandAges 18–65 - NCT07228117Recruiting
Testing a new automated insulin pump for people with diabetes
This study tests a new automated insulin delivery system (a pump that helps manage blood sugar) in children and adults with diabetes. It aims to see if the system is safe and easy to use in daily life.
Little Rock, ArkansasAges 7–85 - NCT06372613Recruiting
LRG protein and ulcerative colitis remission
This study looks at a protein called LRG in your blood or tissue to see if it can tell if your ulcerative colitis is in remission (quiet or not active). This might help doctors better monitor and treat UC in the future.
KomaganeAges 20–90 - NCT02257866Recruiting
Study of blood vessel inflammation over time
This study looks at different types of blood vessel inflammation (vasculitis) to learn more about why they happen and how they progress. By joining, you may help doctors better understand these conditions and improve future treatments.
Bethesda, MarylandAges 3 years+ - NCT07758270Recruiting
Brain scan study for multiple sclerosis treatment switch
This study looks at how a new pill for multiple sclerosis (MS) affects brain inflammation and immune cells. It may help people who are already taking an MS medication but want to switch to a different one.
St Louis, MissouriAges 40–70 - NCT07757789Recruiting
Platelet changes in antiphospholipid syndrome
This study looks at how platelet counts change over time in people with antiphospholipid syndrome (APS), a condition that can cause blood clots and pregnancy problems. It may help doctors better understand and manage low platelets in APS patients.
Al Khārjah, Kharga OasisAges 18 years+ - NCT07426484RecruitingPhase 4
Testing cosibelimab for advanced skin cancer in specific patients
This trial tests an immunotherapy drug called cosibelimab for patients with advanced cutaneous squamous cell carcinoma who have either had a kidney transplant or have a blood cancer like lymphoma or myeloma. The goal is to see if it can shrink tumors when surgery or radiation is not an option.
Boston, MassachusettsAges 18 years+ - NCT07461350Enrolling by invitation
Heart health study in people with and without HIV
This study uses MRI scans to look at how stimulant use and inflammation affect the heart in people with and without HIV. It aims to learn more about heart disease risks and may help guide future care.
San Francisco, CaliforniaAges 30 years+ - NCT05658497Recruiting
MS pregnancy registry for Vumerity (diroximel fumarate) exposure
This study collects information about pregnancies in people with multiple sclerosis (MS) who were exposed to Vumerity (diroximel fumarate) or who were not on MS medicines during pregnancy. It helps researchers understand pregnancy outcomes and safety in these situations.
Aurora, ColoradoAges Any age - NCT07571746RecruitingPhase 2
Surovatamig for antibody-mediated kidney disease
This study tests a new medicine called surovatamig for adults with a specific type of kidney disease caused by the body's own antibodies (anti-PLA2R antibody-positive membranous nephropathy). The medicine may help reduce kidney damage and improve kidney function.
Los Angeles, CaliforniaAges 18–75 - NCT07059507Recruiting
Thyroid cancer in Graves' disease patients having thyroid surgery
This study looks at how often thyroid cancer is found by accident in people with Graves' disease who have their thyroid removed. It helps doctors understand who might be at higher risk so they can plan better care.
Minya, Minya GovernorateAges 18–75 - NCT07191249RecruitingPhase 2
Mosunetuzumab for low-tumor-burden follicular lymphoma
This trial tests a new drug, mosunetuzumab, given as a shot under the skin for people with a slow-growing type of lymphoma (follicular lymphoma) that has not yet been treated and is not causing heavy symptoms or large tumor masses.
HaifaAges 18 years+ - NCT07704580RecruitingPhase 1/Phase 2
Sarilumab for active rheumatoid arthritis
This trial tests sarilumab, an injected antibody that blocks a key protein involved in inflammation, for people with moderate-to-severe rheumatoid arthritis (RA) who haven't had success with standard treatments. The goal is to see if adding sarilumab can help control joint pain and swelling.
Hollywood, FloridaAges 18 years+ - NCT07014293Recruiting
Building resilience after lymphoma treatment
This study tests a program to help people who recently finished treatment for lymphoma build resilience and cope with the challenges of survivorship. It uses telehealth so you can join from home.
Boston, MassachusettsAges 18 years+ - NCT07041099RecruitingPhase 1
Study of CLN-978 for Sjögren's disease
This trial tests an experimental drug called CLN-978, given as a shot under the skin, that helps your immune system target and destroy disease-causing B cells. It's for people with moderate to severe Sjögren's disease who haven't had success with other treatments.
Orlando, FloridaAges 18 years+ - NCT06773936Enrolling by invitationPhase 2
Adding asciminib to usual care for adults with newly diagnosed Ph+ ALL
This trial tests if adding asciminib, a targeted pill, to standard treatment works better for adults newly diagnosed with a specific type of acute lymphoblastic leukemia (Ph+ ALL). It is for those who are older, or who cannot or choose not to have intensive chemotherapy.
Orange, CaliforniaAges 60 years+ - NCT06795126Enrolling by invitation
Virtual reality for pain and anxiety in kids getting IVs
This study tests if a virtual reality game called Little NIRVANA can help reduce pain and anxiety in children getting an IV. It's for kids ages 2 to 8 in the emergency department.
Columbus, OhioAges 2–8 - NCT06329375Recruiting
Food Help for Diabetes Patients After Hospital Stay
This study helps people with diabetes who are admitted to Stanford Hospital and have trouble affording enough food. It provides meals through Mom's Meals after you go home, to make sure you have healthy food options.
Palo Alto, CaliforniaAges 18 years+ - NCT07245992RecruitingPhase 1
Study of F8IL10 injections for rheumatoid arthritis
This trial tests if a new drug called F8IL10, given as an injection directly into an inflamed joint, can help people with rheumatoid arthritis. It is for adults who have had RA for more than 6 months and still have joint swelling despite their current medications.
Reggio Emilia, Reggio EmiliaAges 18–80 - NCT05391490RecruitingPhase 1
Testing donated immune cells for advanced CD19 blood cancers
This early-phase trial tests donated (allogeneic) immune cells engineered to recognize CD19, a target found on many B-cell cancers. It’s designed for people whose CD19+ cancer has come back or didn’t respond after several previous treatments, aiming to shrink tumors and control disease.
LondonAges 16–65 - NCT05201534Recruiting
Math and thinking skills training for school-age children
This trial studies interventions to improve math and cognitive (thinking) skills in elementary school children. It includes both children with math learning difficulties and typically developing children, using tests and MRI brain scans for those who can participate.
Palo Alto, CaliforniaAges 6–12
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,236 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,675 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.