Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,230 recruiting studies in this area right now.
By phase
- Not applicable3,147
- Phase 21,063
- Phase 1819
- Phase 1/Phase 2442
- Phase 3425
- Phase 4238
- Phase 2/Phase 396
Top conditions
- Multiple Sclerosis343
- Multiple Myeloma332
- Asthma194
- Lymphoma182
- Rheumatoid Arthritis140
- Type 1 Diabetes133
- Atopic Dermatitis129
- Systemic Lupus Erythematosus125
- Acute Lymphoblastic Leukemia122
- HIV Infections116
- Chronic Lymphocytic Leukemia100
- Autoimmune Diseases81
- Follicular Lymphoma74
- Diabetes Mellitus, Type 169
- Hodgkin Lymphoma67
- Rheumatoid Arthritis (RA)66
- Leukemia64
- Type 1 Diabetes Mellitus63
Leading sponsors
- Institute of Hematology & Blood Diseases Hospital, China91
- National Institute of Allergy and Infectious Diseases (NIAID)90
- National Cancer Institute (NCI)73
- Assistance Publique - Hôpitaux de Paris70
- M.D. Anderson Cancer Center63
- Novartis Pharmaceuticals60
- AstraZeneca57
- City of Hope Medical Center47
- Mayo Clinic46
- Memorial Sloan Kettering Cancer Center44
Where studies are running
- California491
- Maryland195
- Alabama175
- Florida144
- Arizona142
- New York123
- Massachusetts119
- Texas118
- Illinois81
- Colorado77
Recruiting studies6,230 total
- NCT07169695RecruitingPhase 2
Comparing a new eye drop to cyclosporine for eye allergy in kids
This study tests a new eye drop (T1695) against cyclosporine for children with moderate to severe vernal keratoconjunctivitis, a type of eye allergy. It aims to see which treatment works better and is safer for reducing symptoms.
Kolkata, West BengalAges 4–17 - NCT07171983RecruitingPhase 1
Testing a new drug for rheumatoid arthritis
This trial tests a new medication (BMS-986454) for people with rheumatoid arthritis who haven't responded well enough to methotrexate. It aims to see if the drug is safe and how it works in the body.
Hyderabad, Andhra PradeshAges 18–65 - NCT07172243Recruiting
Amycon biobank and data registry for amyloidosis
This study collects blood and tissue samples and health data from people with amyloidosis to build a biobank and registry. Researchers hope this will help improve future diagnosis and treatment.
LeuvenAges 18 years+ - NCT07173296Recruiting
Bleaching gel application and tooth sensitivity
This study tests two different ways of applying a gentle bleaching gel to see if one causes less tooth sensitivity. It's for people who want to whiten their front teeth and have no history of sensitivity or prior whitening.
IrbidAges 18–35 - NCT07174102Recruiting
Looking at lung scans in rheumatoid arthritis and related diseases
This trial studies lung scans (HRCT) from patients with rheumatoid arthritis, interstitial lung disease, or connective tissue disease to better understand lung involvement. If you have one of these conditions and have had a lung CT, you may be able to help.
PragueAges 18 years+ - NCT07174843RecruitingEarly Phase 1
CAR-T cell therapy for autoimmune diseases
This study tests a new type of cell therapy called CAR-T cells that target three proteins (CD19, CD22, BCMA) to treat people with autoimmune diseases that have not responded to standard treatments. The goal is to see if it can reset the immune system and reduce disease activity.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT07174973Recruiting
New balance training for better stability in MS
This study tests two new balance-training programs for people with Multiple Sclerosis. One program combines balance exercises with mild electrical stimulation on the legs, while the other uses walking exercises on a treadmill with special visual feedback. Both aim to improve balance and help your brain make new connections.
Toronto, OntarioAges 18–65 - NCT07175493RecruitingPhase 1/Phase 2
CM336 for relapsed or refractory autoimmune cytopenia
This study tests a new drug called CM336 for people whose immune system mistakenly attacks their own blood cells (autoimmune cytopenia) and hasn't been controlled by other treatments. The goal is to see if CM336 can safely help improve blood cell counts.
Zhengzhou, HenanAges 18 years+ - NCT07176624Recruiting
Early prone positioning and tube feeding in ICU
This study tests whether early prone positioning (lying on your stomach) and early tube feeding can help people with severe lung failure in the ICU recover faster. It's for adults with organ failure and severe ARDS who can safely be placed on their stomach.
Changchun, JilinAges 18 years+ - NCT07177911RecruitingPhase 1
Study of CC312 for moderate to severe lupus
This trial tests a new medicine called CC312 for people with moderate to severe lupus (SLE) that hasn't improved with standard treatments. The goal is to see if it is safe and can help control the disease.
Chengdu, SichuanAges 18–65 - NCT07178431RecruitingPhase 1/Phase 2
CAR T-cell therapy for worsening multiple sclerosis
This trial tests a new treatment called MB-CART2019.1, which uses your own immune cells to fight multiple sclerosis. It is for people with progressive or worsening MS who have not responded well to other treatments.
BerlinAges 18–55 - NCT07178925Recruiting
Long-term study of antiphospholipid syndrome
This trial follows patients with antiphospholipid syndrome over time to learn more about the condition. It may help researchers understand how the disease progresses and how to better manage it.
RouenAges 18–75 - NCT07179471Recruiting
Fake Carbs Practice with MiniMed 780G for Kids with T1D
This trial tests whether using a practice 'fake carbs' method helps children and teens with type 1 diabetes manage their glucose levels better with the MiniMed 780G insulin pump in auto mode.
Athens, AtticaAges 7–19 - NCT07179679RecruitingPhase 1
Study of a new shot for multiple myeloma
This trial tests a new injectable treatment for people with multiple myeloma that has come back or not responded to previous therapies. It aims to see if the drug is safe and effective.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT07180992Recruiting
Monocytes and CART cell response in multiple myeloma
This trial looks at how certain immune cells (monocytes) affect the success of CART cell therapy for multiple myeloma. It may help doctors improve treatment for future patients.
AmiensAges 18 years+ - NCT07181369RecruitingPhase 1
Study of GTX-B001 for chronic inducible urticaria
This trial tests a new drug, GTX-B001, in healthy people and those with a type of hives called chronic inducible urticaria (specifically cold-induced or scratch-induced hives). The goal is to see if it's safe and helps control symptoms that don't respond well to standard antihistamines.
BerlinAges 18–75 - NCT07181941RecruitingPhase 1/Phase 2
Testing lower doses of linvoseltamab for multiple myeloma
This trial tests if a lower dose of linvoseltamab can still work well for people with multiple myeloma that has come back or not responded to treatment. It aims to reduce side effects while keeping the cancer under control.
Seattle, WashingtonAges 18 years+ - NCT07182656RecruitingPhase 1
Safety of CIGB-814 in healthy Chinese volunteers
This is a first-in-human study in China testing a new drug called CIGB-814 in healthy volunteers. The goal is to check how safe the drug is, how well it is tolerated, and how the body processes it.
Beijing, Beijing MunicipalityAges 18–45 - NCT07183423Recruiting
New skin barrier product vs. Vaseline for dry, irritated skin
This study tests a new skin barrier product against a standard moisturizer (petrolatum) to see which works better for mild to moderate skin problems like eczema, psoriasis, or dry skin. It may help improve your skin's barrier and reduce symptoms.
Makati City, National Capital RegionAges 18 years+ - NCT07183657Recruiting
Tracking inhaler use in lung disease
This study looks at how well people with COPD or asthma use their inhalers. It aims to understand common problems and find ways to improve treatment adherence.
Hradec KrálovéAges 18 years+ - NCT07183683Recruiting
Acupuncture for bladder problems in women with MS
This study tests whether stimulating acupuncture points on the lower leg can help women with multiple sclerosis who have overactive bladder symptoms like urgency, frequent urination, or leaking. It is for women with relapsing-remitting MS who are not using a catheter regularly.
Berlin, State of BerlinAges 18–60 - NCT07184450RecruitingPhase 1
CAR-T cell therapy for children with hard-to-treat rheumatic diseases
This trial tests a new treatment using your child's own immune cells, modified to target B cells and fight severe rheumatic diseases like juvenile dermatomyositis, arthritis, scleroderma, or Sjogren's syndrome. It's for children who haven't improved with standard treatments.
Hangzhou, ZhejiangAges 5 years+ - NCT07184853Recruiting
Ruxolitinib with etanercept vs ruxolitinib for severe GVHD
This trial tests whether adding etanercept to ruxolitinib works better than ruxolitinib alone for severe graft-versus-host disease (GVHD) that has not responded to steroids. GVHD is a common complication after a stem cell transplant where donor cells attack the patient's body.
Hangzhou, ZhejiangAges 12–70 - NCT07185178Recruiting
Video game breathing exercises for asthma-COPD overlap
This trial tests if breathing exercises performed through video games can improve respiratory function in people with Asthma-COPD Overlap Syndrome (ACOS). It may help those who have breathing difficulties but are otherwise stable.
Kocaeli, IzmitAges 40–80
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,230 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,763 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.