Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,230 recruiting studies in this area right now.
By phase
- Not applicable3,147
- Phase 21,063
- Phase 1819
- Phase 1/Phase 2442
- Phase 3425
- Phase 4238
- Phase 2/Phase 396
Top conditions
- Multiple Sclerosis343
- Multiple Myeloma332
- Asthma194
- Lymphoma182
- Rheumatoid Arthritis140
- Type 1 Diabetes133
- Atopic Dermatitis129
- Systemic Lupus Erythematosus125
- Acute Lymphoblastic Leukemia122
- HIV Infections116
- Chronic Lymphocytic Leukemia100
- Autoimmune Diseases81
- Follicular Lymphoma74
- Diabetes Mellitus, Type 169
- Hodgkin Lymphoma67
- Rheumatoid Arthritis (RA)66
- Leukemia64
- Type 1 Diabetes Mellitus63
Leading sponsors
- Institute of Hematology & Blood Diseases Hospital, China91
- National Institute of Allergy and Infectious Diseases (NIAID)90
- National Cancer Institute (NCI)73
- Assistance Publique - Hôpitaux de Paris70
- M.D. Anderson Cancer Center63
- Novartis Pharmaceuticals60
- AstraZeneca57
- City of Hope Medical Center47
- Mayo Clinic46
- Memorial Sloan Kettering Cancer Center44
Where studies are running
- California491
- Maryland195
- Alabama175
- Florida144
- Arizona142
- New York123
- Massachusetts119
- Texas118
- Illinois81
- Colorado77
Recruiting studies6,230 total
- NCT07154524Recruiting
Immunoadsorption for CIDP treatment study
This trial tests whether a blood-filtering treatment called immunoadsorption can help people with CIDP. It is for adults who are already receiving or starting IVIg or MP therapy.
Ulm, Baden-WurttembergAges 18 years+ - NCT07155252Recruiting
Home glucose test for type 1 diabetes screening
This study looks at whether you can do an oral glucose tolerance test at home instead of at a clinic. It is for people who have certain antibodies linked to type 1 diabetes or who were recently diagnosed with type 1 diabetes.
New Haven, ConnecticutAges 8–45 - NCT07155226RecruitingPhase 1/Phase 2
Study of AZD3632 for advanced blood cancers with certain gene changes
This trial is testing a new drug, AZD3632, either alone or with other cancer treatments, for people with advanced blood cancers that have specific genetic changes (like KMT2Ar, NPM1m, or others that cause HOX over-expression). The goal is to see if it can help when standard treatments have stopped working.
Decatur, IllinoisAges 16 years+ - NCT07155954Recruiting
Super-Resolution Ultrasound to Tell Benign from Malignant Lymph Nodes
This study uses a special high-detail ultrasound technique to better tell if lymph nodes are harmless (benign) or cancerous (malignant). It may help avoid unnecessary biopsies or surgeries in the future.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07157462Recruiting
Testing a multi-strain probiotic for year-round allergies
This trial tests if a special probiotic blend can help people with year-round allergic rhinitis (nasal allergies) caused by common indoor allergens like dust mites, cat, or dog dander. Volunteers will take the probiotic daily and track their symptoms.
Strasbourg, AlyatecAges 18 years+ - NCT07159620RecruitingPhase 2
New drug combo for rare leukemia type (ETP-ALL)
This trial tests a combination of drugs (venetoclax, azacitidine, chidamide, vindesine, and dexamethasone) in people newly diagnosed with a rare subtype of T-cell acute lymphoblastic leukemia called ETP-ALL or near-ETP-ALL. The goal is to see if this drug cocktail can improve outcomes.
Suzhou, JiangsuAges 14–65 - NCT07159789Recruiting
Brain stimulation to improve leg weakness in MS
This study tests whether a noninvasive brain stimulation technique (rTMS) can help people with multiple sclerosis who have leg stiffness and weakness. You will receive daily sessions over two weeks to see if it improves walking and quality of life.
Gatineau, QuebecAges 18–70 - NCT07160075RecruitingPhase 4
HIV prevention with PrEP for people on opioid therapy
This trial tests if daily PrEP medication can help prevent HIV in people receiving opioid replacement therapy. You must be HIV-negative and regularly attend your opioid treatment program to join.
Calgary, AlbertaAges 16 years+ - NCT07160231RecruitingPhase 4
Lowering dose of JAK inhibitors for rheumatoid arthritis or psoriatic arthritis
This trial tests if reducing the dose of a JAK inhibitor can keep your inflammatory arthritis under control. If you have rheumatoid arthritis, psoriatic arthritis, or axial spondyloarthritis and are in a stable remission, you may be able to take a lower dose.
Nijmegen, GelderlandAges 16 years+ - NCT07160270Recruiting
Nerve problems in Waldenström's macroglobulinemia
This study looks at how common nerve problems (peripheral neuropathy) are in people with Waldenström's macroglobulinemia (WM), and how to best diagnose them. It aims to help doctors find nerve issues earlier and improve care.
København ØAges Any age - NCT07160608RecruitingPhase 2
Study of Tarperprumig for ANCA-associated vasculitis
This trial tests a new drug (tarperprumig) for people with active ANCA-associated vasculitis (GPA or MPA). The goal is to see if it is safe and effective for treating the disease, especially when standard treatments like rituximab or cyclophosphamide are being considered.
Ciudad de Buenos AiresAges 18–80 - NCT07160868Recruiting
Sleep apnea and severe asthma study
This study looks at whether people with difficult-to-treat asthma might also have obstructive sleep apnea. If you're on high-dose asthma treatments, this trial could help find out if sleep problems are making your asthma worse.
Dublin, DublinAges 18–90 - NCT07161271Recruiting
Study on a low-flow CO2 removal device for breathing failure
This study looks back at medical records of people who used a special device (ECCO2R) in the ICU to help remove carbon dioxide from the blood. The goal is to see if the device is safe and works well for patients with breathing problems.
Hong KongAges 18 years+ - NCT07162012RecruitingEarly Phase 1
Cell therapy for EBV-positive lymphoma
This trial tests a new cell therapy (TCR-T cells) for people with EBV-positive lymphoma that has not responded to standard treatments or has come back. The therapy uses your own immune cells that have been specially trained to find and attack cancer cells carrying the EBV virus.
ShanghaiAges 18–70 - NCT07163221Recruiting
At-home ultrasound therapy for rheumatoid arthritis
This trial tests if a device that uses ultrasound waves, used at home, can help treat rheumatoid arthritis (RA). It is for people with moderate to severe RA who still have symptoms despite taking standard medications.
Glendale, ArizonaAges 18 years+ - NCT07163338Recruiting
Antiphospholipid syndrome in older stroke patients
This study looks for a blood clotting disorder called antiphospholipid syndrome (APS) in people aged 65 and older who have had a stroke or a mini-stroke (TIA). The goal is to understand how common APS is in this group and if it affects recovery.
ReimsAges 65 years+ - NCT07163611RecruitingPhase 2/Phase 3
Obinutuzumab for PLA2R antibodies in membranous nephropathy
This study is testing a drug called obinutuzumab to see if it can lower PLA2R antibodies in people with membranous nephropathy (a kidney disease). The goal is to reduce protein leakage in urine and improve kidney health.
NijmegenAges 18 years+ - NCT07164560RecruitingPhase 1
CAR-NK cell therapy for relapsed T-cell lymphoma
This trial tests a new treatment using immune cells (CAR-NK) made from donated cord blood. These cells are designed to find and attack T-cell lymphoma that has come back or not responded to other treatments. The goal is to see if this approach is safe and effective.
Hangzhou, ZhejiangAges 18–75 - NCT07166211RecruitingPhase 2
Study of CM512 injection for chronic hives
This trial tests a new injection (CM512) for people with chronic spontaneous urticaria, also known as chronic hives. If you have had itchy hives for at least 6 weeks despite taking regular antihistamines, this study may help find a new treatment option.
Tianjin, Tianjin MunicipalityAges 18–75 - NCT07166939RecruitingPhase 4
Asthma rescue inhaler study after emergency visit
This study tests a new rescue inhaler (Airsupra) for people with asthma after an emergency visit. It may help you manage your asthma at home with fewer side effects.
Cleveland, OhioAges 18–54 - NCT07167381Recruiting
Tumor testing to find cancer treatments for Florida patients
This study tests your tumor sample to find which drugs might work best for your cancer. It is for both children and adults whose cancer has come back or not responded to treatment, and who have already tried at least one standard therapy.
Miami, FloridaAges Any age - NCT07167680Recruiting
Fall prevention for wheelchair users with MS or spinal cord injury
This trial tests a program to help prevent falls for people with multiple sclerosis or spinal cord injury who use a wheelchair or scooter. You will learn physical skills with a care partner to stay safe.
Urbana, IllinoisAges 18 years+ - NCT07167693RecruitingPhase 1/Phase 2
Testing arginine for diabetic ketoacidosis in type 2 diabetes
This trial tests if an IV medicine called arginine hydrochloride can help manage diabetic ketoacidosis (DKA) in people with type 2 diabetes. It's for those who come to the ER with very high blood sugar and ketones.
Detroit, MichiganAges 18 years+ - NCT07169500RecruitingPhase 1/Phase 2
CAR-T with or without stem cell transplant for young women with myeloma
This trial tests a new immune cell therapy (BCMA-CART) alone or combined with a stem cell transplant for women aged 18-55 with multiple myeloma. It aims to see if this treatment is safe and effective.
Tianjin, Tianjin MunicipalityAges 18–50
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,230 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,763 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.