Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,230 recruiting studies in this area right now.
By phase
- Not applicable3,147
- Phase 21,063
- Phase 1819
- Phase 1/Phase 2442
- Phase 3425
- Phase 4238
- Phase 2/Phase 396
Top conditions
- Multiple Sclerosis343
- Multiple Myeloma332
- Asthma194
- Lymphoma182
- Rheumatoid Arthritis140
- Type 1 Diabetes133
- Atopic Dermatitis129
- Systemic Lupus Erythematosus125
- Acute Lymphoblastic Leukemia122
- HIV Infections116
- Chronic Lymphocytic Leukemia100
- Autoimmune Diseases81
- Follicular Lymphoma74
- Diabetes Mellitus, Type 169
- Hodgkin Lymphoma67
- Rheumatoid Arthritis (RA)66
- Leukemia64
- Type 1 Diabetes Mellitus63
Leading sponsors
- Institute of Hematology & Blood Diseases Hospital, China91
- National Institute of Allergy and Infectious Diseases (NIAID)90
- National Cancer Institute (NCI)73
- Assistance Publique - Hôpitaux de Paris70
- M.D. Anderson Cancer Center63
- Novartis Pharmaceuticals60
- AstraZeneca57
- City of Hope Medical Center47
- Mayo Clinic46
- Memorial Sloan Kettering Cancer Center44
Where studies are running
- California491
- Maryland195
- Alabama175
- Florida144
- Arizona142
- New York123
- Massachusetts119
- Texas118
- Illinois81
- Colorado77
Recruiting studies6,230 total
- NCT07225530Recruiting
Screening and treatment for cervical cancer in women with HIV
This trial tests a program to screen and treat HIV-positive women for cervical cancer in La Romana, Dominican Republic. It may help catch and manage cervical cancer early.
La RomanaAges 25 years+ - NCT07225543RecruitingPhase 2
Study of 2-HOBA for women with lupus
This trial tests whether a natural compound called 2-HOBA can help women with lupus who also have mildly high blood pressure. It aims to improve blood vessel health and reduce inflammation.
Nashville, TennesseeAges 18 years+ - NCT07225738Recruiting
Multiple Myeloma treatment and cannabis use study
This study follows people with newly diagnosed multiple myeloma to see how their cancer treatments and use of medications, including cannabis, affect their health. It will help doctors learn more about what works best.
Goodyear, ArizonaAges 18 years+ - NCT07225868Recruiting
Coaching to boost cognitive rehab in MS
This trial tests if coaching in goal-directed behavior can improve cognitive rehabilitation for people with relapsing-remitting or secondary progressive MS. It aims to help patients better manage daily tasks and thinking challenges.
Buffalo, New YorkAges 18–65 - NCT07225985RecruitingPhase 1/Phase 2
Pralatrexate, bendamustine, and radiation before donor stem cell transplant for T-cell lymphoma
This trial tests a combination of two chemotherapy drugs (pralatrexate and bendamustine) plus total-body radiation before a donor stem cell transplant for people with T-cell lymphoma that has come back or hasn't responded to treatment. The goal is to see if this approach can help destroy the lymphoma and allow the donor cells to take hold safely.
Seattle, WashingtonAges 18 years+ - NCT07226323Recruiting
WeCare for mental health and medication adherence in South Africa
This trial tests a counselling program called WeCare to help men who have sex with men in Johannesburg stick to their HIV or PrEP medication and manage depression symptoms. It is designed for those who are struggling with adherence or have unsuppressed HIV.
JohannesburgAges 18 years+ - NCT07226609Recruiting
Plant-based diet study for multiple myeloma patients
This study tests if a plant-based diet can help people with newly diagnosed multiple myeloma who are receiving a standard 4-cycle drug combination (DRVd). Researchers want to see if changing what you eat might improve treatment results.
Basking Ridge, New JerseyAges 18 years+ - NCT07226843RecruitingPhase 1
Study of a new drug for adults with certain blood cancers
This trial tests a new drug, LY4584180, for adults with several types of non-Hodgkin lymphoma who have already had at least two prior treatments. The goal is to see if the drug can help shrink tumors and stop the cancer from growing.
Scottsdale, ArizonaAges 18 years+ - NCT07226934Recruiting
AI-generated question list for blood cancer patients
This trial tests if an AI tool can help you create a personalized list of questions about your cancer treatment to ask your doctor at your next visit. It is for patients with lymphoma or multiple myeloma who get regular infusion therapy.
St Louis, MissouriAges 18–99 - NCT07228026Recruiting
Device to Monitor Asthma by Measuring Nitric Oxide in Breath
This trial tests a handheld device that measures nitric oxide in your breath to see if it can help monitor asthma. You may qualify if you have uncontrolled asthma and can use the device at home.
Stockton, CaliforniaAges 5–100 - NCT07228741RecruitingPhase 2
Exercise and medicine for heart health in ALL survivors with obesity
This trial tests if combining resistance exercise with the weight-loss medication tirzepatide can improve heart and metabolic health in survivors of childhood acute lymphoblastic leukemia (ALL) who are now adults and have obesity or overweight with related health issues. You may benefit if you finished treatment at least 2 years ago and meet weight and health criteria.
Memphis, TennesseeAges 18 years+ - NCT07230015Recruiting
Imagery and balance training for MS
This study tests if combining mental practice of movements with balance exercises helps people with relapsing-remitting MS who have mild balance problems and dizziness. It aims to improve stability and reduce vertigo.
Istanbul, Beykoz/İstanbulAges 18–45 - NCT07230353RecruitingPhase 1
Plamotamab for moderate to severe rheumatoid arthritis
This trial tests a new treatment called plamotamab for people with moderate to severe rheumatoid arthritis (RA) who have not had enough relief from current treatments. The goal is to see if it is safe and to help control RA symptoms.
TbilisiAges 18 years+ - NCT07230483RecruitingPhase 2
Long-term safety of CM512 for atopic dermatitis
This study is for people who have already completed a previous study of CM512 for atopic dermatitis. It will check if the medicine is safe and works well over a longer period.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07231952RecruitingPhase 2
Pirtobrutinib, venetoclax, and rituximab for Waldenstrom's macroglobulinemia
This trial tests a combination of three drugs (pirtobrutinib, venetoclax, and rituximab) for people newly diagnosed with Waldenstrom's macroglobulinemia who have not had treatment before and need therapy for their symptoms.
Boston, MassachusettsAges 18 years+ - NCT07233213RecruitingPhase 3
IVIG for chronic low platelet condition
This trial tests an intravenous immunoglobulin (IVIG) treatment for chronic immune thrombocytopenia (ITP), a condition where the immune system attacks platelets, causing low counts and bleeding risk. It aims to safely raise platelet levels using donated antibodies.
Ankara, AltındağAges 18–65 - NCT07233642RecruitingPhase 1
Fast CD19 CAR-T therapy for lupus not helped by standard treatment
This trial tests a quick-made CAR-T cell therapy for children and adults with active lupus who haven't gotten better with standard drugs. The goal is to see if targeting a protein called CD19 on certain immune cells can calm the disease.
Hangzhou, ZhejiangAges 5 years+ - NCT07233720Recruiting
Zanubrutinib plus rituximab for first-line marginal zone lymphoma
This trial tests a combination of two targeted drugs (zanubrutinib and rituximab) as a first treatment for marginal zone lymphoma. The goal is to see how well this drug pair works for people who have not received any prior cancer therapy.
Zhengzhou, HenanAges Any age - NCT07234019RecruitingPhase 2
Rituximab plus anti-CD38 antibody for ITP
This trial tests whether adding an anti-CD38 antibody to the standard drug rituximab works better than rituximab alone for adults with long-term immune thrombocytopenia (ITP) who have already tried steroids without lasting success.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT07234162RecruitingPhase 3
Study comparing golidocitinib to standard therapy for relapsed T-cell lymphoma
This trial tests a new drug, golidocitinib, against a standard treatment chosen by your doctor for peripheral T-cell lymphoma that has come back or not responded to prior therapy. The goal is to see which approach works better for patients.
Hefei, AnhuiAges 18 years+ - NCT07234487RecruitingPhase 2
Comparing two drug combos for advanced Hodgkin lymphoma
This trial tests a newer, lower-dose immunotherapy combination (AVD plus nivolumab) against a standard intensive chemo regimen (BEACOPP) that is adjusted based on PET scan results. It is for people with advanced classical Hodgkin lymphoma that has not been treated before.
MoscowAges 18–60 - NCT07234747Recruiting
Core stability: exergaming vs. standard exercises for kids with JIA
This study compares two types of core-strengthening exercises for children with juvenile idiopathic arthritis (JIA). One group does standard core-stability exercises, and the other plays active video games (exergaming) that work the same muscles. The goal is to see which approach works better and is more fun for kids.
Istanbul, BuyukcekmeceAges 8–12 - NCT07234773RecruitingPhase 1
Study of a new injectable drug for rheumatoid arthritis
This early-stage study tests a new injectable medicine (KT501) for people with moderate to severe rheumatoid arthritis who have not responded well enough to other treatments and have specific antibodies in their blood. It aims to see how safe and well-tolerated the drug is.
BayswaterAges 18–75 - NCT07234825Recruiting
Trial of dairy-free diet with liquid nutrition for eosinophilic esophagitis
This study tests whether a dairy-free diet combined with a special liquid nutrition drink (called Kate Farms) can help children and young adults with eosinophilic esophagitis (a condition where certain white blood cells build up in the esophagus and cause trouble swallowing, pain, or vomiting). The goal is to see if this combination can reduce symptoms and improve quality of life.
Seattle, WashingtonAges 1–21
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,230 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,763 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.