Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,051 recruiting studies in this area right now.
By phase
- Not applicable2,997
- Phase 21,057
- Phase 1792
- Phase 1/Phase 2437
- Phase 3436
- Phase 4234
- Phase 2/Phase 398
Top conditions
- Multiple Sclerosis330
- Multiple Myeloma327
- Asthma193
- Lymphoma178
- Rheumatoid Arthritis132
- Type 1 Diabetes130
- Atopic Dermatitis125
- Systemic Lupus Erythematosus119
- Acute Lymphoblastic Leukemia118
- HIV Infections106
- Chronic Lymphocytic Leukemia95
- Autoimmune Diseases77
- Follicular Lymphoma70
- Rheumatoid Arthritis (RA)68
- Diabetes Mellitus, Type 163
- Hodgkin Lymphoma63
- Leukemia63
- Mantle Cell Lymphoma62
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)97
- Institute of Hematology & Blood Diseases Hospital, China85
- National Cancer Institute (NCI)74
- Assistance Publique - Hôpitaux de Paris65
- AstraZeneca63
- M.D. Anderson Cancer Center58
- Novartis Pharmaceuticals58
- Mayo Clinic49
- City of Hope Medical Center48
- Memorial Sloan Kettering Cancer Center45
Where studies are running
- California496
- Maryland200
- Alabama178
- Florida149
- Arizona147
- Massachusetts116
- New York116
- Texas112
- Illinois83
- Colorado82
Recruiting studies6,051 total
- NCT07654842Enrolling by invitationPhase 4
Fasenra asthma study with smart inhaler
This study tests a new way to take asthma medicine using a device that tracks your inhaler use. If you already use Fasenra (benralizumab) for severe asthma, you may be able to join.
Skokie, IllinoisAges 18 years+ - NCT07651891RecruitingPhase 4
Dog allergy vaccine study for Swedish adults
This study tests an allergy shot (Alutard SQ Dog) for people with moderate to severe dog allergies. It aims to see how well the vaccine works in Swedish medical practices.
Lund, Skåne CountyAges 18–50 - NCT07653347Recruiting
Infant RSV immunity study
Researchers want to study how infants naturally fight RSV infections. You and your baby may join if your baby is born in April, May, June, September, October, or November at BC Women's Hospital or a nearby hospital.
Vancouver, British ColumbiaAges Up to 6 months - NCT07654426RecruitingPhase 2
Heart protection during lymphoma chemotherapy
This trial tests if a heart-protecting drug (dexrazoxane) can prevent heart damage in people getting chemotherapy for certain types of large B-cell lymphoma. It is for patients who already have heart risk factors or a history of heart failure.
Boston, MassachusettsAges 18 years+ - NCT07652879RecruitingPhase 2
KCD drug combination for newly diagnosed POEMS syndrome
This trial tests a combination of three drugs (carfilzomib, cyclophosphamide, and dexamethasone) for people newly diagnosed with POEMS syndrome. It aims to see how well this treatment helps control the disease and its symptoms.
ShanghaiAges 18–75 - NCT07646262Recruiting
Gluten-Free vs Mediterranean Diet for Rheumatoid Arthritis
This study compares two eating patterns—a gluten-free diet and a Mediterranean diet—to see which might help reduce inflammation and improve symptoms in people with rheumatoid arthritis. You would follow one diet for the study period while your doctors monitor how you feel.
Gaziantep, ŞehitkamilAges 19–65 - NCT07652905RecruitingPhase 2
CM336 with Isa-VR for newly diagnosed plasma cell leukemia
This trial tests a new combination treatment for people who have just been diagnosed with primary plasma cell leukemia. The treatment includes a study drug called CM336 along with other cancer-fighting medicines. It aims to see if this combination helps control the disease.
Tianjin, Tianjin MunicipalityAges 18–75 - NCT07652580Recruiting
Toxins, immunity, and B-cell lymphoma
This study looks at how exposure to toxins might affect your immune system if you have B-cell non-Hodgkin lymphoma. You'll provide blood and skin samples, plus have your genes sequenced, to help researchers find links between environmental exposures and lymphoma.
Bethesda, MarylandAges 4 years+ - NCT07653984Recruiting
Study on immune diseases in women of childbearing age
This study follows women with certain immune disorders affecting the nervous system (like multiple sclerosis or myasthenia gravis) to understand how these conditions affect reproduction. Healthy women planning pregnancy are also included for comparison.
Guangzhou, GuangdongAges 20–55 - NCT06686472RecruitingPhase 2
Testing TL-925 eye drops for allergic conjunctivitis
This trial tests an investigational eye drop called TL-925 to see if it can treat allergic conjunctivitis (eye allergies). If you have a history of eye allergies and a positive allergy skin test, you may be able to join.
Memphis, TennesseeAges 18 years+ - NCT07642557Recruiting
Real-world remibrutinib use for chronic hives in Germany
This study observes how remibrutinib (a newer medication) works for chronic hives (CSU) when prescribed in routine clinical practice in Germany. Remibrutinib is used when standard allergy medications don't work well enough. The study tracks your symptoms and treatment over 24 months to understand how well it helps real patients.
DürenAges 18 years+ - NCT07642362Recruiting
Digital Support to Improve Quality of Life in Multiple Myeloma
This trial tests a digital app designed to help people with multiple myeloma (a blood cancer) manage their quality of life and symptoms. The study wants to see if using this app on a phone or computer can help patients feel better and stay connected to their care.
AthensAges Any age - NCT07645248RecruitingPhase 3
Safety study of two asthma inhaler propellants over 4 weeks
This trial compares the safety of two different propellants (the gases that push medicine out of inhalers) in people with well-controlled asthma. Researchers want to ensure both propellants are safe to use in asthma inhalers.
Aventura, FloridaAges 18 years+ - NCT07645820Recruiting
Testing a device to detect eczema flares early
This study tests a non-invasive home device called Nevisense Go that may help detect atopic dermatitis (eczema) flares before they become severe. You'll use the device at home, track your symptoms, and visit the clinic a few times to see if it helps predict when flares are coming.
Phoenix, ArizonaAges 12–89 - NCT07643766RecruitingPhase 2
Testing ENV-294 for moderate-to-severe atopic dermatitis
This study tests whether a new medication called ENV-294 can help adults with moderate-to-severe atopic dermatitis (eczema) that hasn't responded well to other treatments. The trial will check if the drug reduces itching and skin inflammation safely.
Encinitas, CaliforniaAges 18 years+ - NCT07638345Recruiting
AI-powered weight management for teens with diabetes or asthma
This study tests a smartphone app that uses artificial intelligence to help families manage weight and health for teenagers (ages 12–21) with Type 1 Diabetes or asthma. The app is designed to be personalized to each family's needs and may help improve overall health outcomes.
SevilleAges 18 years+ - NCT07641426RecruitingPhase 1/Phase 2
CID-103 Treatment for Kidney Transplant Rejection
This study tests an experimental drug called CID-103 to treat antibody-mediated rejection (ABMR), a type of immune response that damages transplanted kidneys. The drug targets immune cells that attack the transplant, and researchers hope it may help preserve kidney function and prevent transplant failure.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06034275RecruitingPhase 1
Study of VIP943 for CD123-positive blood cancers
This trial tests a new drug called VIP943 for people with advanced acute myeloid leukemia (AML), B-cell acute lymphoblastic leukemia (B-ALL), or myelodysplastic syndrome (MDS) whose cancer cells have a marker called CD123. It is for those who have tried all other treatments or cannot receive them.
Birmingham, AlabamaAges 18 years+ - NCT07638007Recruiting
How targeted therapy affects thinking and memory in blood cancer
This study examines whether a new type of cancer medication affects thinking, memory, and focus in people with chronic myeloid leukemia (CML) or chronic lymphocytic leukemia (CLL). Researchers will compare people starting this medication with healthy volunteers to understand any changes.
Rochester, New YorkAges 18 years+ - NCT07638683RecruitingPhase 2
Teclistamab and Daratumumab for New Multiple Myeloma With Amyloidosis
This trial tests a combination of two newer cancer-fighting drugs (teclistamab and daratumumab) to treat people who have just been diagnosed with multiple myeloma—a blood cancer—and also have light chain amyloidosis, a condition where abnormal proteins build up in organs. The goal is to see if this combination works better and is safe for newly diagnosed patients.
ShanghaiAges 18 years+ - NCT07643948Recruiting
How HIV Treatment Changes Affect Drug Resistance
This study follows people with HIV whose virus is well-controlled on current medications to understand how switching to a different HIV drug regimen affects the virus's ability to resist those drugs. The goal is to help doctors choose the safest treatment switches.
Hong Kong, Hong KongAges 18 years+ - NCT07639177RecruitingPhase 2
Fecal Microbiota Transplant for Hard-to-Treat Rheumatoid Arthritis
This trial tests whether transferring healthy gut bacteria from a donor to patients with rheumatoid arthritis that hasn't improved on standard medications can reduce joint pain and swelling. The goal is to see if rebalancing the gut microbiome (the community of bacteria in your intestines) helps control inflammation.
Beijing, Beijing MunicipalityAges 18–65 - NCT07645573RecruitingEarly Phase 1
Imaging test of lymph vessels using a new tracer
This early-stage study tests a new imaging method using a radioactive tracer to visualize lymph vessels in the belly and chest. Researchers want to understand how this imaging works in healthy people and in patients with suspected blockages in lymph vessels.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07638735Enrolling by invitation
Greener asthma inhaler prescribing tool
This study tests a tool that helps doctors choose asthma inhalers that are better for the environment. It may help your clinic reduce its carbon footprint while keeping your patients' asthma well managed.
Toronto, OntarioAges 16 years+
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,051 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,083 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.