Nephrology & urology
Kidney & urinary clinical trials
Kidney disease and conditions of the bladder and urinary tract. We’re tracking 4,504 recruiting studies in this area right now.
By phase
- Not applicable2,821
- Phase 2565
- Phase 1364
- Phase 3271
- Phase 1/Phase 2229
- Phase 4195
- Phase 2/Phase 359
Top conditions
- Prostate Cancer653
- Bladder Cancer190
- Acute Kidney Injury136
- Chronic Kidney Diseases131
- Breast Cancer105
- Chronic Kidney Disease104
- Renal Cell Carcinoma80
- Urinary Incontinence63
- Kidney Cancer60
- Colorectal Cancer58
- Ovarian Cancer58
- Lung Cancer54
- Lupus Nephritis53
- Cancer51
- Melanoma50
- Benign Prostatic Hyperplasia48
- Head and Neck Cancer46
- Prostate Cancer (Adenocarcinoma)46
Leading sponsors
- Mayo Clinic62
- National Cancer Institute (NCI)45
- Peking University First Hospital38
- M.D. Anderson Cancer Center36
- Chinese University of Hong Kong34
- Novartis Pharmaceuticals34
- AstraZeneca29
- Memorial Sloan Kettering Cancer Center29
- Assistance Publique - Hôpitaux de Paris28
- University of California, San Francisco28
Where studies are running
- California350
- Alabama111
- Arizona103
- Florida97
- New York96
- Texas92
- Maryland90
- Massachusetts88
- Illinois66
- Minnesota47
Recruiting studies4,504 total
- NCT05940415Recruiting
Active surveillance without prostate biopsy for low-risk suspects
This study checks whether people with a low chance of prostate cancer can be monitored closely without having an immediate prostate biopsy. It uses PSA blood tests and prostate MRI to sort who may safely wait.
Hefei, AnhuiAges 18 years+ - NCT05942053RecruitingPhase 4
Vitamin K2 for chronic kidney disease with high urine protein
This trial studies whether vitamin K2 can help people with chronic kidney disease (kidney damage that lasts months or longer), especially those with higher protein levels in the urine. It compares vitamin K2 use in a specific group and watches kidney-related health outcomes and safety.
Tanta, Capital of Gharbia Governorate.Ages 18 years+ - NCT05942027RecruitingPhase 4
CoQ10 in early-to-moderate kidney disease with high urine protein
This study tests whether taking coenzyme Q10 can improve chronic kidney disease in adults with moderate kidney function and higher urine protein. It also looks at safety, especially for blood pressure and potassium levels.
Tanta, Capital of Gharbia Governorate.Ages 18 years+ - NCT05942625RecruitingPhase 1
Study of an experimental drug in healthy adults
This Phase 1 trial tests how safe and tolerable an experimental medicine (HS-10390) is in healthy adults, and how the body processes it. It is not for people with an illness, but for healthy volunteers to help researchers understand the drug before future studies.
Nanjing, JiangsuAges 18–45 - NCT05943379RecruitingPhase 2
RC48 antibody plus gemcitabine for high-risk bladder cancer
This Phase 2 study tests RC48, an antibody-based drug, combined with gemcitabine to treat high-risk, non-muscle invasive bladder cancer that has not responded well to BCG or cannot receive BCG. It may help shrink tumors and reduce the chance of the cancer coming back.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05944016RecruitingPhase 3
Dapagliflozin for early Alport kidney disease in teens and young adults
This trial tests dapagliflozin, a daily medicine, to slow kidney problems in people with early-stage chronic kidney disease caused by Alport syndrome. It may help protect kidney function and reduce worsening over time.
Heidelberg, Baden-WürttenbergAges 10–39 - NCT05944237RecruitingPhase 1/Phase 2
Early trial for advanced cancers using HTL0039732
This is a Phase 1/2 study testing how well HTL0039732 works and is tolerated in people with advanced solid tumors that have not responded to standard treatments. It may help by offering a new treatment option and learning which cancer types and body markers respond best.
CambridgeAges 18 years+ - NCT05946213RecruitingPhase 3
Shorter radiation treatment for high-risk prostate cancer
This trial tests whether a shorter course of radiation works as well as the usual longer course for people with high-risk prostate cancer. The goal is to keep cancer control while possibly reducing treatment time and inconvenience.
Birmingham, AlabamaAges 18 years+ - NCT05946824RecruitingPhase 2
Radiation for prostate cancer that returned after surgery
This trial tests a new way of delivering radiation for prostate cancer that has come back after prostate surgery. It may help control the cancer by targeting the “prostate bed” area or nearby lymph nodes where it returned.
Rochester, New YorkAges 18 years+ - NCT05948657Recruiting
PSMA PET-CT scan for men on prostate cancer surveillance
This study checks whether a special prostate scan called PSMA PET-CT (along with standard monitoring scans) can help guide care while you are on “active surveillance” instead of immediate treatment. It may help doctors track low-risk prostate cancer changes more accurately over time.
Los Angeles, CaliforniaAges 18 years+ - NCT05949567Recruiting
Testing whether body position changes bladder overactivity diagnosis
This study checks whether where you are positioned during a bladder test (urodynamic assessment) changes how bladder overactivity is diagnosed. It may help improve how doctors confirm the cause of overactive bladder symptoms in people with multiple sclerosis or Parkinson’s disease.
Paris, FranceAges 18 years+ - NCT05951075Recruiting
Power prenatal vitamins study for men with specific sperm results
This study looks at whether a specific “power” prenatal vitamin helps improve sperm measures in men whose at-home sperm test results fall in a certain range. It’s mainly for men living in the US or Canada who aren’t taking other prenatal vitamins already and don’t have known causes of male infertility.
Encino, CaliforniaAges 18–50 - NCT05952947RecruitingPhase 1
Study drug for HPV18-positive solid tumors with a specific immune marker
This Phase 1 trial tests HRYZ-T101 injection for people whose solid cancer is HPV18-positive and who have the HLA-DRB1*0901 immune marker. It is meant for people whose cancer has returned or spread and who have few or no effective treatment options.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT05955001RecruitingPhase 2/Phase 3
Tadalafil for early urinary symptoms after prostate surgery
This trial studies whether daily tadalafil (5 mg) can improve early urinary trouble and erection function after endoscopic prostate tissue removal. It may help men whose urinary symptoms continued even after prior medicine.
Al Mansurah, Dakahlia GovernorateAges 40–80 - NCT05961111RecruitingEarly Phase 1
Oncolytic virus injection for advanced solid tumors
This early-phase trial tests an injection of a virus designed to attack cancer cells in people with advanced solid tumors. It is meant for situations where standard treatments have not worked (or you can’t/won’t take them) and when doctors can directly deliver the treatment to a tumor spot.
Linyi, ShandongAges 18–75 - NCT05962541RecruitingPhase 4
Using bladder scans to plan repeat surgery for bladder cancer
This trial checks whether a bladder scan and score (VI-RADS from MRI) can help doctors choose the right way to do a second look surgery for non-muscle-invasive bladder cancer. The goal is to reduce the chance of needing extra (“secondary”) resections while still catching important disease early.
Rome, LazioAges 18 years+ - NCT05963126Recruiting
Fetuin A test to predict kidney function decline
This study looks at a blood protein called fetuin A to see if it can forecast worsening kidney function over time in people with treated high blood pressure. It may help identify who is at higher risk for kidney decline so care can be adjusted earlier.
Ostrava, Czech RepublicAges 18–100 - NCT05965180Recruiting
Fine-needle scan during prostate biopsy
This study tests a special fine-needle “photoacoustic” scan used during a planned prostate biopsy. It aims to better assess prostate cancer tissue patterns, which may improve how doctors evaluate biopsies.
Ann Arbor, MichiganAges 40–80 - NCT05968885RecruitingPhase 4
Compare Botox and combination medicines for overactive bladder
This study tests whether Botox injections work better than a combination of medicines (anti-muscarinics plus a beta-3 medicine) for people whose overactive bladder symptoms did not improve with one medicine alone. It may help by improving bladder control and reducing urgent, hard-to-hold urine leaks or frequent urination.
TaipeiAges 20–90 - NCT05969496RecruitingPhase 2
Pembrolizumab plus axitinib before kidney surgery for RCC with IVC tumor
This Phase 2 trial tests whether pembrolizumab plus axitinib can shrink kidney cancer before surgery, when there is tumor growth into the inferior vena cava (IVC). It may help make the operation easier and improve chances of long-term control.
Aurora, ColoradoAges 18 years+ - NCT05969964Recruiting
Testing whether repeat surgery can be avoided after bladder tumor removal
This trial looks at whether people with early bladder cancer can safely skip a second surgery after their first procedure fully removed the tumor with clear margins. It may help avoid extra procedures and associated discomfort, if your cancer meets the study’s “low-risk” criteria.
Al Mansurah, Dakahlia GovernorateAges 18–80 - NCT05970172RecruitingPhase 3
Roxadustat for anemia in kids with chronic kidney disease
This study tests roxadustat, a medicine that helps the body make more red blood cells, in children and teens with anemia caused by chronic kidney disease. It may help improve anemia and related blood counts, while also monitoring safety.
BrusselsAges 2–17 - NCT05970341Recruiting
Healthy food program for kidney disease and better kidney health
This trial tests whether a structured “eat well” food program—focused on kidney-friendly nutrition—can help people with early to mid-stage chronic kidney disease. It may help by supporting healthier day-to-day eating over at least 6 months.
Houston, TexasAges 18 years+ - NCT05974774RecruitingPhase 3
Intermittent hormone therapy for metastatic prostate cancer with low PSA
This trial studies whether taking hormone therapy in breaks (instead of continuously) can work for people with metastatic prostate cancer whose PSA is very low after prior treatment with hormone-deprivation plus an AR pathway inhibitor. It may help reduce time on treatment while still keeping cancer controlled.
CopenhagenAges 18–100
Common questions
- How many kidney & urinary clinical trials are recruiting?
- Clin2 is tracking 4,504 recruiting nephrology & urology studies from the U.S. registry right now, out of 7,195 we cover in this area in total.
- What does “Kidney & urinary” cover here?
- Kidney disease and conditions of the bladder and urinary tract. We group each study into kidney & urinary based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a kidney & urinary trial near me?
- Use the search to filter kidney & urinary studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.