Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,626 recruiting studies in this area right now.
By phase
- Not applicable4,298
- Phase 2850
- Phase 1470
- Phase 3425
- Phase 1/Phase 2309
- Phase 4208
- Phase 2/Phase 366
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Acute Respiratory Distress Syndrome72
- Ovarian Cancer72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona155
- Massachusetts128
- Florida117
- New York113
- Maryland111
- Texas90
- Pennsylvania83
- Colorado71
Recruiting studies6,626 total
- NCT04903262Recruiting
Extra CO2 removal to protect lungs in moderate ARDS
This study tests an “extra-CO2 removal” breathing support approach to help protect the lungs in people with moderate ARDS, a serious lung injury. You would be on a ventilator for a short time, and the team would check whether this approach improves breathing outcomes while aiming to be safer for the lungs.
BolognaAges 18–100 - NCT04903951RecruitingPhase 2
Check if early breathing support after stroke helps sleep apnea
This trial tests whether starting a breathing-support treatment soon after a first stroke improves outcomes in people who also have sleep apnea. It may help reduce complications and support recovery if you meet the specific timing and health criteria.
Matosinhos MunicipalityAges 18–80 - NCT04908696Recruiting
Treatment study for laryngeal and hypopharyngeal cancers
This trial tests treatment approaches for people with cancers of the voice box (larynx) or lower throat (hypopharynx). It may help by finding which treatment strategy works best for different tumor locations and cancer stages.
Shanghai, Shanghai MunicipalityAges 18–90 - NCT04913311Recruiting
Testing markers to predict lung inflammation after lung cancer treatment
This study looks for early “predictive markers” to tell who is most likely to develop lung inflammation after standard treatment for non-small cell lung cancer. It may help clinicians spot problems sooner and tailor care, using additional monitoring during treatment.
Houston, TexasAges Any age - NCT04916990Recruiting
Care program for rural adults with several lung and head cancers
This study looks at how to improve care for adults with certain cancers who live in rural areas and may face access problems. It mainly focuses on people receiving cancer treatment at specific Colorado-area hospitals, and who are uninsured or underinsured.
Aurora, ColoradoAges 18–99 - NCT04918095Recruiting
COPD home monitoring with a phone or tablet
This study tests a home monitoring program for people with COPD (a long-term lung condition) to track symptoms using a phone or tablet. It may help clinicians spot changes earlier and improve how COPD care is managed.
Ventura, CaliforniaAges 40–100 - NCT04919382RecruitingPhase 2
Temozolomide plus atezolizumab for advanced small cell lung cancer
This trial studies temozolomide plus atezolizumab in people with metastatic or recurring small cell lung cancer that has already come back or progressed after standard platinum chemotherapy plus immunotherapy. It may help by trying a new combination after prior treatment has stopped working.
Chicago, IllinoisAges 18 years+ - NCT04919265Recruiting
Mother and baby health study from early pregnancy
This study follows pregnant people and their babies from the first few months of pregnancy through at least one year after birth. It aims to learn how health and development turn out, especially for mothers who can keep coming to the same clinic for follow-up.
Kajang, SelangorAges 18–45 - NCT04926584Recruiting
Immunotherapy for advanced or limited-spread lung cancer
This trial tests whether starting immunotherapy can help people with newly diagnosed advanced or limited-spread non-small cell lung cancer that cannot be fully cured with standard local treatments. It may offer a new treatment approach when surgery or definitive chemoradiation isn’t a good option.
Esslingen am NeckarAges 18 years+ - NCT04930432RecruitingPhase 1/Phase 2
MCLA-129 for advanced EGFR- and MET-positive lung and other cancers
This early-phase trial tests MCLA-129, an antibody that targets EGFR and MET, in people with advanced cancers that have specific lab “biomarker” results. It’s for patients whose cancer has grown after standard treatments or can’t take standard treatment, with the goal of shrinking tumors and improving symptoms.
BaodingAges 18 years+ - NCT05735717RecruitingPhase 2
T-cell transplant using depleted receptors for blood cancers
This Phase 2 study tests a specialized stem cell transplant that removes certain immune “T-cell” receptors to help treat blood cancers like acute leukemia. It may help your body rebuild a healthier immune system after high-dose treatment.
Minneapolis, MinnesotaAges Up to 60 years - NCT05339568Recruiting
Smartphone support program for people with advanced lung cancer
This trial tests a “whole process follow-up” care plan, using a smartphone, to support people with non-small cell lung cancer from diagnosis through treatment and follow-up. It may help you manage care steps more smoothly if you’re not a candidate for curative (radical) treatment or don’t want surgery.
Jinan, ShandongAges 18 years+ - NCT07224490RecruitingPhase 1
Kisspeptin test for brain function after COVID-19
This study tests how the brain's reproductive hormone system works after a COVID-19 infection using a substance called kisspeptin. It may help explain symptoms like changes in periods or hormone levels in people with long COVID.
Boston, MassachusettsAges 18–60 - NCT07699328RecruitingPhase 1/Phase 2
Study of VRN110755 for EGFR-mutant lung cancer
This trial tests a new oral targeted therapy (VRN110755) for people with EGFR-mutant lung cancer. It is for those whose cancer has advanced or spread, and who either have not been treated yet or who stopped responding to previous EGFR pills.
Bedford Park, South AustraliaAges 18 years+ - NCT07699341Recruiting
Heimlich maneuver training for mothers of children with disabilities
This study offers a free training session to teach mothers of children with disabilities how to perform the Heimlich maneuver (a lifesaving technique to help someone who is choking). The goal is to help you feel confident and prepared to act quickly if your child or another family member starts choking.
AdıyamanAges 18 years+ - NCT05628376Recruiting
Tracking lung cancer evolution through treatment
This study follows people with lung cancer over time to see how the disease changes, especially during and after treatment. By collecting tumor samples and blood tests every few months, researchers hope to understand why some cancers come back or become resistant, and find better ways to treat them.
LondonAges 18 years+ - NCT04626154Recruiting
Testing a device for breathing problems during chest movement
This study looks at how well a special device can be used in children to understand breathing problems related to chest and belly movement. It may help researchers improve care for kids who have breathing distress.
Boston, MassachusettsAges 4 weeks–17 years - NCT07699666Recruiting
Cord clamping timing for preterm babies
This study compares waiting a bit before clamping the umbilical cord versus clamping it right away for babies born between 32 and 37 weeks of pregnancy. It helps determine which approach may be better for preterm infants.
Tunis, Tunis GovernorateAges birth+ - NCT07699861Recruiting
Thoracic cancers during pregnancy registry
This registry collects information on thoracic cancers (like lung cancer, mesothelioma, or chest tumors) that occur during pregnancy. It helps doctors learn more about how to care for both the mother and baby.
BadenAges 18 years+ - NCT05798923RecruitingPhase 2
LAM-001 for lung scarring with high blood pressure
This trial tests a new medication called LAM-001 for people with high blood pressure in the lungs caused by lung scarring. It aims to see if it can improve symptoms and help you feel better.
Tucson, ArizonaAges 18–80 - NCT07289711Recruiting
Study of ARDS subtypes for targeted treatment
This study looks at different types of inflammation in patients with Acute Respiratory Distress Syndrome (ARDS), a serious lung condition. It aims to find which treatments work best for each subtype.
Nanjing, JiangsuAges 18 years+ - NCT07536308RecruitingPhase 1
Nasal COVID-19 booster vaccine safety trial
This trial tests a new nasal spray COVID-19 booster vaccine. It aims to see if the vaccine is safe and produces a strong immune response when given through the nose and inhaled, in people who have already been vaccinated.
Decatur, GeorgiaAges 18–64 - NCT06726148RecruitingPhase 1/Phase 2
Study of ECI830 for advanced breast cancer and solid tumors
This trial is testing a new drug called ECI830, either alone or with another drug, for people with advanced breast cancer or other solid tumors that have not responded to standard treatments. It may be an option if you have HR+/HER2- breast cancer, small cell lung cancer, or a tumor with a specific gene change (CCNE1 amplification).
Los Angeles, CaliforniaAges 18–100 - NCT07699614Recruiting
Lung health and germs in adults in Botswana
This study looks at how the lungs and tiny organisms in the body (microbiome) work together in adults living in Botswana. It may help doctors understand how to keep lungs healthier, especially for people with or without HIV.
GaboroneAges 35 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,626 recruiting pulmonology studies from the U.S. registry right now, out of 10,582 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.