Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,637 recruiting studies in this area right now.
By phase
- Not applicable4,308
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2309
- Phase 4208
- Phase 2/Phase 366
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Acute Respiratory Distress Syndrome72
- Chronic Obstructive Pulmonary Disease (COPD)72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona156
- Massachusetts128
- Florida116
- New York113
- Maryland111
- Texas90
- Pennsylvania83
- Illinois72
Recruiting studies6,637 total
- NCT05847634Recruiting
Testing how deep sedation affects blood flow in ARDS
This study looks at whether giving deep sedation (and sometimes muscle-paralyzing medicines) changes blood flow and oxygen delivery in the brain during acute respiratory distress syndrome (ARDS). It is a pilot study, meaning it mainly aims to understand safety and gather early information.
Winnipeg, ManitobaAges 18 years+ - NCT05848713RecruitingPhase 3
Blood-thinner treatment for complications of community pneumonia
This Phase 3 trial tests whether an anti-clot “blood thinner” can reduce complications from community-acquired pneumonia in hospitalized adults who need extra oxygen. It may help by lowering harmful clot-related effects during serious lung infection.
Chicago, IllinoisAges 18 years+ - NCT05849077Recruiting
Testing oxygen saturation targets during newborn resuscitation
This study looks at the best oxygen saturation targets and resuscitation approach for very premature babies right after birth. It may help clinicians guide breathing support more safely in the first minutes of life.
Dallas, TexasAges birth–10 minutes - NCT05849129RecruitingPhase 2
IV vitamin C added to first treatment for advanced lung cancer
This Phase 2 study tests whether adding an IV (into a vein) form of vitamin C (“ascorbic acid”) to standard first-line chemotherapy, with or without immunotherapy, can improve outcomes for people with stage IIIB/IV non-small cell lung cancer. You might benefit if the trial matches your cancer stage and upcoming treatment plan.
Ottawa, OntarioAges 18 years+ - NCT05849779RecruitingPhase 3
Breathing sevoflurane to help prevent ARDS in ICU patients
This Phase 3 trial tests whether inhaled sevoflurane (a breathing anesthetic) can help prevent ARDS, a serious lung injury, in high-risk ICU patients who need sedation. It aims to reduce the chance of developing ARDS by using this medication during the early period on a breathing machine.
Clermont-Ferrand, Not Required For This CountryAges 18 years+ - NCT05851859Recruiting
Breathing training for long COVID symptoms
This study tests whether a structured breathing control technique can improve symptoms of long COVID. It may help by training how you breathe, but you must meet specific health and medication criteria to join.
Saint-DenisAges 18 years+ - NCT05852990RecruitingPhase 3
Gut help to prevent diarrhea from EGFR-targeted lung cancer drugs
This Phase 3 trial tests whether adding glutamine plus L. reuteri can help prevent severe diarrhea caused by EGFR-targeted treatments in people with advanced non-small cell lung cancer. If it works, it could make treatment easier to tolerate and help you stay on the planned therapy.
Mexico City, Mexico CityAges 18–80 - NCT05854563Recruiting
Study using collected cough samples to learn about lung disease
This trial looks at “cough capture” samples to better understand what is happening in the lungs. You might be eligible if you’re having a bronchoscopy for medical reasons and don’t already have lung cancer.
The Bronx, New YorkAges 21 years+ - NCT05855317Recruiting
Tests blood marker link to lung blood clots in ARDS
This study looks at a blood marker (EV-TF) to see whether it helps predict pulmonary embolism—blood clots in the lungs—in people with ARDS who are in the ICU. Results may help doctors better identify who is at higher risk.
MarseilleAges 18 years+ - NCT05855369RecruitingPhase 2/Phase 3
Smell training plus brain stimulation for long COVID smell loss
This study tests whether a combination of smell training and a type of nerve stimulation can improve persistent smell problems after COVID. It is meant for people who had normal smell before COVID and still struggle with smell changes months later.
Charleston, South CarolinaAges 18–65 - NCT05855330RecruitingPhase 2
Arginine treatment for kids hospitalized with COVID-19
This Phase 2 trial tests whether replacing the body’s arginine (an amino acid) can improve outcomes for children and young adults hospitalized with COVID-19. It may help the immune response, but you must meet several safety criteria to join.
Atlanta, GeorgiaAges 3–21 - NCT05856981RecruitingPhase 1
Testing ADU-1805 for advanced solid tumors safety
This early study tests whether ADU-1805 is safe in people with advanced solid tumors and checks how the body processes the drug. Depending on your cancer type, it may also be looking specifically at certain cancers that have not yet received PD-(L)1 immunotherapy.
Detroit, MichiganAges 18 years+ - NCT05857800Recruiting
Studying how lung tumor treatment affects the tumor environment
This trial studies how “before-surgery” (neoadjuvant) lung cancer treatments change the tumor environment by monitoring patients during care. It may help doctors better choose therapies and predict who benefits from treatment.
ShanghaiAges 18 years+ - NCT05857774Recruiting
Study breathing muscle changes in ICU patients on ventilation
This study looks at how the muscles used for breathing work and change in ICU patients who are placed on breathing machines, then follows outcomes after they leave the hospital. It may help doctors better predict recovery and long-term health after ventilation.
Toronto, OntarioAges 18 years+ - NCT05857891Recruiting
Erythropoietin to help clear lung fluid in ARDS
This trial tests whether erythropoietin (EPO), a medicine that affects red blood cell production, can help clear extra fluid from the lungs in people with acute respiratory distress syndrome (ARDS). If it works, it could improve breathing and reduce lung fluid buildup during critical illness.
Wenzhou, ZhejiangAges 18 years+ - NCT05857995Recruiting
Personalized survivorship care program for rural lung cancer survivors
This study tests a personalized care program to help people who have had lung cancer manage life after treatment. It focuses on survivors living in rural areas, aiming to improve follow-up care and support.
Lexington, KentuckyAges 18 years+ - NCT05858502Recruiting
Study immune response to COVID-19 and improve testing
This study looks at how the immune system in the body responds to different COVID-19 virus variants. It may help improve how COVID-19 is diagnosed by comparing people who are currently infected and those who are not.
ParisAges 18–65 - NCT05860387Recruiting
Testing faster diagnosis of serious lung fungal infection
This study aims to detect invasive lung aspergillosis earlier by testing samples from your lungs and measuring specific lab markers. It may help doctors start the right antifungal treatment sooner when the infection is suspected.
Havířov, Moravian-Silesian RegionAges 18 years+ - NCT05865002RecruitingPhase 1
Safety and drug test for AUR107 in advanced cancers
This early-phase study tests whether AUR107 is safe and may help shrink or control advanced solid tumors that have come back or progressed. You may be considered if standard treatments no longer work and you meet specific blood, organ, and health requirements.
Vijayawada, Andhra PradeshAges 18 years+ - NCT05865730RecruitingPhase 2
Oncobax immune treatment for advanced lung and kidney cancers
This trial tests Oncobax®-AK, an immune-based treatment, in people with advanced (stage IV) non-squamous lung cancer or clear cell kidney cancer. It seeks to see if the treatment can help cancer respond better and whether it is safe for patients who meet specific immune and health requirements.
MonsAges 18 years+ - NCT05866952Recruiting
Breathing and blood-flow testing in long-COVID symptoms
This trial studies how the lungs’ breathing (airflow) and blood flow may be off in people with long-COVID symptoms like tiredness, shortness of breath, or trouble exercising. It may help researchers understand what’s driving symptoms and what kinds of abnormalities could be targeted.
Boston, MassachusettsAges 18–99 - NCT05867472RecruitingPhase 3
Sedation plan for critically ill children on breathing machines
This Phase 3 trial tests a sedation approach using inhaled (“volatile”) anesthesia gases for children who need a ventilator. It aims to improve comfort and brain-related outcomes while they stay on the breathing machine for at least a day.
Hamilton, OntarioAges 1 month–18 years - NCT05868239Recruiting
Testing an aerosol box during CPR emergencies
This study tests whether using an aerosol “box” during cardiopulmonary resuscitation (CPR) during an emergency improves safety and care. It’s mainly aimed at trained healthcare staff who can perform required tasks during CPR.
Los Angeles, CaliforniaAges 18–60 - NCT05873387Recruiting
Stethoscope tool to detect pulmonary hypertension
This study tests a computer “listening” algorithm that uses an electronic stethoscope to help detect pulmonary hypertension. It may help spot this condition earlier by turning routine heart-lung exams into more informative screenings.
Providence, Rhode IslandAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,637 recruiting pulmonology studies from the U.S. registry right now, out of 10,624 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.