Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,637 recruiting studies in this area right now.
By phase
- Not applicable4,308
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2309
- Phase 4208
- Phase 2/Phase 366
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Acute Respiratory Distress Syndrome72
- Chronic Obstructive Pulmonary Disease (COPD)72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona156
- Massachusetts128
- Florida116
- New York113
- Maryland111
- Texas90
- Pennsylvania83
- Illinois72
Recruiting studies6,637 total
- NCT05874401RecruitingPhase 4
Trilaciclib added to topotecan for advanced small cell lung cancer
This study tests whether adding trilaciclib (a medicine given with chemotherapy) can improve outcomes for people with extensive-stage small cell lung cancer who are being treated with topotecan. It compares trilaciclib versus a placebo (inactive pill) while you receive topotecan.
SevilleAges 18 years+ - NCT05875870Recruiting
Bright light and exercise program for lung or esophageal cancer
This trial tests whether a structured bright-light exposure routine combined with a specific exercise program can help people with newly diagnosed lung or esophageal cancer. You may be eligible if you’re in early-to-middle cancer stages and able to safely participate in walking-based activities.
Taipei City, TaipeiAges 20 years+ - NCT05878717RecruitingPhase 2/Phase 3
Belimumab for adults with scleroderma lung scarring
This Phase 2/3 study tests whether belimumab can improve outcomes and safety in adults with systemic sclerosis (scleroderma) that has caused lung scarring. It may help by reducing active or worsening immune-driven disease in the lungs.
Phoenix, ArizonaAges 18 years+ - NCT05878964Recruiting
Study of skin health and quality of life during cancer treatment
This trial looks at how cancer treatments (anti–PD-1/PD-L1/CTLA-4 medicines or CDK inhibitors) affect your skin and overall quality of life. You may fill out questionnaires during the study to help researchers understand changes over time.
RomaAges 18 years+ - NCT05880108Recruiting
Behavior program to help COVID recovery in Veterans
This study tests whether a behavioral (lifestyle) program can improve recovery from COVID-19, especially for Veterans with different body weights. It looks at people who either have never had COVID before or had COVID more than 90 days ago.
Baltimore, MarylandAges Up to 80 years - NCT05881031Recruiting
Home breathing support for medically complex children
This trial studies whether starting a noninvasive breathing machine (given without a tube in the airway) at home works well and is tolerated in children with medical complexity. It may help improve comfort and safety when new breathing support is prescribed.
Toronto, OntarioAges 5 years–17.9 years - NCT05881798Recruiting
Vena cava filter data study for specific filter type
This study checks outcomes and safety using real-world health data from people who received a specific type of vena cava filter. It may help improve future care by understanding how these devices perform after placement.
Los Angeles, CaliforniaAges 18 years+ - NCT05883137Recruiting
High-flow nasal oxygen during intubation in the ICU
This trial looks at using a special, fast-flow oxygen device through the nose during intubation in critically ill adults. It may help keep oxygen levels safer while a breathing tube is placed.
Stockholm, Stockholm CountyAges 18–100 - NCT05885698Recruiting
Study of care patterns in newly diagnosed lung cancer
This observational study follows adults with newly diagnosed non-small cell lung cancer to understand what treatments are used and how patients are doing. It may help doctors better understand how care decisions affect outcomes, and it does not require the study to give an experimental treatment.
Daphne, AlabamaAges 18 years+ - NCT05886439RecruitingPhase 1/Phase 2
Study drug plus PD-1 or PD-L1 for lung cancer
This Phase 1/2 trial tests a new treatment called LK101 combined with a PD-1 or PD-L1 antibody for advanced lung cancer. It may help shrink tumors and improve control of the disease, especially after prior anti–PD-1/PD-L1 treatment has stopped working.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05886816RecruitingPhase 2
Mitoquinone pills to prevent COVID-19 after risky exposure
This trial tests whether an oral medication (mitoquinone/mitoquinol) taken after a high-risk COVID-19 exposure can help prevent you from becoming sick. It is designed for people who currently have no symptoms but had a significant exposure to someone with confirmed COVID-19.
Dallas, TexasAges 18–65 - NCT05889013Recruiting
Nasal swab testing to guide care for kids with breathing issues
This study checks whether special nose tests help doctors choose the best treatments for children with long-term breathing and airway symptoms. It may help your child get more targeted care based on the test results.
Hartford, ConnecticutAges 2 years+ - NCT05889546Recruiting
Rapid autopsy protocol for small cell lung cancer patients
This study looks at a planned, faster way to collect information from patients’ bodies after death who have small cell lung cancer. The goal is to better understand the disease and potentially improve future care, with consent from the patient or their authorized representative.
Indianapolis, IndianaAges 18 years+ - NCT05890599Recruiting
Yoga or health education for ongoing fatigue after COVID
This trial studies whether a yoga program (compared with health education) can reduce persistent tiredness after COVID-19. It may help if your fatigue has lasted at least 12 weeks and you think it started with COVID.
StuttgartAges 18–65 - NCT05890729RecruitingPhase 1/Phase 2
XTMAB-16 for lung sarcoidosis that still causes breathing trouble
This early-phase study tests XTMAB-16 to improve lung sarcoidosis in people who still have symptoms despite standard steroid-type treatment. It may help reduce inflammation and improve breathing, while also learning the safest dose and how the treatment works in humans.
Birmingham, AlabamaAges 18–80 - NCT05891886RecruitingEarly Phase 1
Testing supplemental oxygen for early blood clot in the lungs
This early-phase trial studies whether giving extra oxygen can help people with a recently diagnosed lung blood clot (pulmonary embolism). It mainly looks at people who have early symptoms and signs that the right side of the heart is under strain.
Boston, MassachusettsAges 18 years+ - NCT05892614RecruitingPhase 2
Efzofitimod for early systemic sclerosis lung scarring
This trial tests efzofitimod to see if it can improve or slow lung disease caused by systemic sclerosis (scleroderma), and to check safety and side effects. It focuses on people with relatively early disease and measurable lung involvement on lung scans.
Los Angeles, CaliforniaAges 18 years+ - NCT05892549Recruiting
Phone-based monitoring to detect worsening COVID-19 early
This study tests whether a phone app that listens to your voice and breathing can spot signs your COVID-19 is getting worse sooner. If you qualify, you’ll use the COVOICE app on your mobile phone for monitoring.
Saint-MandéAges 18 years+ - NCT05894070Recruiting
Using your voice recordings to spot cancer coming back
This study looks at whether changes in your voice can help detect early return of laryngeal or hypopharyngeal cancer. If you’ve finished curative treatment and are disease-free for a certain period, your voice will be monitored to see if it can signal recurrence sooner.
BernAges 18 years+ - NCT05894616Recruiting
Home monitoring study for lasting breathing symptoms after COVID
This study looks at people with lingering post-COVID symptoms, especially breathing and lung-related findings, using home monitoring and medical tests. It may help researchers understand what’s driving ongoing symptoms and identify patterns that could guide better care.
Stockholm, SverigeAges 18–50 - NCT05895409Recruiting
Study risk factors in progressive lung scarring
This study looks at what factors contribute to worsening lung scarring seen on scans in people with certain lung diseases. Results may help doctors better understand and predict who will worsen over time.
Jinan, ShandongAges 18–80 - NCT05896579Recruiting
Study heart function during rest and exercise in COPD
This study measures how well the right side of your heart works when you are resting and when you exercise, in people with chronic obstructive pulmonary disease (COPD). It may help researchers better understand COPD-related heart strain and guide future care.
Aurora, ColoradoAges 40 years+ - NCT05896800Recruiting
Inhaled nitric oxide for moderate to severe COPD symptoms
This study tests whether inhaled nitric oxide gas can improve outcomes in people with moderate-to-severe chronic obstructive pulmonary disease (COPD). It may help reduce breathing problems by targeting how airways and blood vessels respond in the lungs.
Nanjing, JiangsuAges 40–75 - NCT05897879Recruiting
Study how pertussis germs and immune response affect severity
This study looks at children with suspected pertussis (who need a PCR test) and compares how the bacteria and the immune response relate to how sick they become. It may help doctors understand why some children have worse symptoms and guide future care.
BordeauxAges Up to 15 years
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,637 recruiting pulmonology studies from the U.S. registry right now, out of 10,624 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.