Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,637 recruiting studies in this area right now.
By phase
- Not applicable4,308
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2309
- Phase 4208
- Phase 2/Phase 366
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Acute Respiratory Distress Syndrome72
- Chronic Obstructive Pulmonary Disease (COPD)72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona156
- Massachusetts128
- Florida116
- New York113
- Maryland111
- Texas90
- Pennsylvania83
- Illinois72
Recruiting studies6,637 total
- NCT05898269Recruiting
Predicting fluid needs while lying face down in ARDS
This study tests a way to predict whether you will benefit from a fluid bolus (a small amount of IV fluid) while you are lying face down for ARDS. It uses continuous heart monitoring to guide or evaluate fluid decisions and may help clinicians avoid too much or too little fluid.
Clermont-FerrandAges 18 years+ - NCT05898594Recruiting
Lung cancer screening for high-risk Black adults
This study is designed to help Black adults at higher risk get lung cancer screening. It checks whether a screening approach can catch lung problems early and connect people to the right next steps.
Chicago, IllinoisAges 50–80 - NCT05898529Recruiting
Testing COVID status in children having surgery
This study looks at how COVID-19 infection is handled in children (ages 2–17) who are scheduled for surgery. The goal is to compare testing/safety approaches and see how they may protect pediatric surgical patients.
Surrey, British ColumbiaAges 2–17 - NCT05902559Recruiting
Study of new lung-check biomarkers in older adults
This study looks at new blood or test “biomarkers” to understand how well targeted lung health checks work. You join if you’re already attending the NHS lung health check program and can consent.
LondonAges 55–74 - NCT05903001Recruiting
Breathing muscle testing to help track lung disease
This study checks whether measurements of your breathing muscle (the diaphragm) can act as a useful “biomarker” to track lung disease. You might be asked to do breathing tests and follow study instructions, and your results may help researchers better monitor COPD, asthma, fibrosis, or pulmonary hypertension.
Aachen, North Rhine-WestphaliaAges 18 years+ - NCT05903092RecruitingPhase 2
Monalizumab plus durvalumab for small cell lung cancer
This Phase 2 trial tests whether adding monalizumab to durvalumab (two immune-targeting medicines) can improve outcomes in people with small cell lung cancer. You may be able to join if you have certain stage of small cell lung cancer and have not had the specific prior treatments the study allows.
Indianapolis, IndianaAges 18 years+ - NCT05903430Recruiting
MRI-guided focused radiation for limited spread cancer
This feasibility study tests whether MRI-guided, highly focused radiation can be safely delivered to tumors in the abdomen or central lung. It may help patients with a small number of metastases by aiming treatment more precisely and gathering detailed outcomes for future care.
Manchester, United KingdomAges 18 years+ - NCT05903352RecruitingPhase 3
Personalized antibiotic duration for hospital pneumonia patients
This trial compares how long antibiotics should be given to people hospitalized with moderately severe community-acquired pneumonia. It uses your early improvement to see which antibiotic duration works best and safely.
GarchesAges 18 years+ - NCT05906030Recruiting
Ultrasound to study diaphragm function around surgery
This trial uses ultrasound (a non-painful scanning method) to measure how well the diaphragm works around the time of surgery. It aims to learn whether diaphragm changes during surgery relate to breathing problems, especially in people undergoing abdominal, pelvic, or vascular operations.
Stockholm, Stockholm CountyAges 18–100 - NCT05906472Recruiting
Feeding through a tube after tracheostomy in the ICU
This study tests a specific way of continuing tube feeding for people who need a tracheostomy after being on a breathing tube in the ICU. The goal is to see if this feeding approach is safe and beneficial for recovery.
Danbury, ConnecticutAges 18 years+ - NCT05908227Recruiting
Testing nasal high-flow settings in stable preterm babies
This study tests how different nasal high-flow “flow strength” settings affect breathing stability in preterm infants. It may help clinicians choose settings that keep heart rate and breathing steadier.
Mainz, Rhineland-PalatinateAges 5 months–7 months - NCT05908591Recruiting
Pregnancy sleep study on breathing, blood vessel function, and safety
This study looks at how sleep and breathing changes during pregnancy may affect blood vessel function and pregnancy safety. You may be asked about your sleep and possibly have health checks during the middle of pregnancy.
Edmonton, AlbertaAges 18 years+ - NCT05910827RecruitingPhase 1/Phase 2
Study of a HER3 antibody with cetuximab and possibly docetaxel
This Phase 1/2 trial tests whether an antibody that targets HER3 (with cetuximab, and possibly docetaxel) can help treat advanced squamous cell cancers that have already been treated or cannot use standard options. It mainly looks at safety first, and also whether the treatment can shrink tumors.
Sydney, New South WalesAges 18 years+ - NCT05911646Recruiting
Tool to help decisions for mild sleep apnea in kids
This trial looks at OSA-18, a questionnaire that may help families and clinicians make better decisions about treatment for a child’s mild sleep apnea. It specifically focuses on children with enlarged tonsils and mild sleep study results.
Hartford, ConnecticutAges 3–12 - NCT05913089RecruitingPhase 2
Testing a new lung cancer drug with chemotherapy or an anti-angiogenesis pill
This Phase 2 trial tests TQB2450 (a new cancer medicine) added to chemotherapy, or along with an oral medicine called anlotinib, for stage II–IIIB non-small cell lung cancer. It may help shrink tumors and improve outcomes in people who are getting curative surgery and have not had prior cancer drug treatment.
Beijing, Beijing MunicipalityAges 18–80 - NCT05913882Recruiting
Breathing training for people with ALS to improve cough
This study tests a breathing and expiratory muscle training program to help people with ALS cough more effectively. It may help reduce breathing and airway trouble by strengthening the muscles used for cough in early-stage ALS.
Fort Lauderdale, FloridaAges 18–90 - NCT05914116RecruitingPhase 1/Phase 2
Early study of DB-1311 with BNT324 for advanced solid tumors
This Phase 1/2a study tests a combination treatment (DB-1311 with BNT324) in people with advanced or metastatic solid cancers that have grown despite standard treatments. It aims to find a safe dose and look for signs the treatment can shrink tumors or slow growth.
Tucson, ArizonaAges 18 years+ - NCT05914649Recruiting
Testing long COVID and POTS brain fog symptoms
This study tests how different long-COVID and POTS-related symptoms—especially “brain fog”—show up and improve. It may help researchers better measure symptoms so future treatments can be targeted more effectively.
Calgary, AlbertaAges 18–60 - NCT05915208Recruiting
Follow-up study for people with histiocytic disorders
This study is checking in over time with people who have a histiocytic disorder. It may help doctors better understand how these conditions behave and what follow-up care works best.
Birmingham, AlabamaAges birth–89 years - NCT05917119Recruiting
Bright light therapy for obstructive sleep apnea symptoms
This study tests whether a “bright light” treatment can reduce daytime sleepiness in people with obstructive sleep apnea who are already using CPAP or BiPAP. It may help people feel more awake during the day without changing their sleep apnea device use.
Pittsburgh, PennsylvaniaAges 40–65 - NCT05919511Recruiting
Questionnaire study for people at risk after stem cell transplant
This observational study follows people who had a stem cell transplant a few months ago to better understand risk for chronic graft-versus-host disease. You won’t get a study treatment; instead, you’ll complete questionnaires over time, and the study team looks at your symptoms and experiences.
Birmingham, AlabamaAges 18 years+ - NCT05920330Recruiting
Study of blocked noses and loss of smell
This study looks at people who have trouble smelling and also feel their nose is blocked. The researchers want to understand what causes these symptoms and how they might be related, which could guide better treatment.
Columbus, OhioAges 18–70 - NCT05922176Recruiting
Microneedle patch testing to predict allergy treatment response
This study uses a small microneedle patch to collect skin-related samples to help predict how well allergy immunotherapy may work. It includes people with house dust mite allergy and also a healthy control group, so researchers can compare biomarker results.
SeoulAges 19–60 - NCT05922345RecruitingPhase 3
Study drug vs docetaxel for advanced lung cancer after prior treatment
This Phase 3 trial compares AL2846 pills plus TQB2450 injections against standard chemotherapy (docetaxel) in people with advanced non-small cell lung cancer. You may qualify if your cancer has progressed after platinum chemotherapy and immunotherapy, and if certain tumor genetic tests are negative.
Hefei, AnhuiAges 18–75
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,637 recruiting pulmonology studies from the U.S. registry right now, out of 10,624 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.