Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,637 recruiting studies in this area right now.
By phase
- Not applicable4,308
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2309
- Phase 4208
- Phase 2/Phase 366
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Acute Respiratory Distress Syndrome72
- Chronic Obstructive Pulmonary Disease (COPD)72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona156
- Massachusetts128
- Florida116
- New York113
- Maryland111
- Texas90
- Pennsylvania83
- Illinois72
Recruiting studies6,637 total
- NCT05989542RecruitingPhase 3
Study of vebreltinib for MET-mutated lung cancer
This study tests a new targeted pill (vebreltinib) for people with advanced non-small cell lung cancer that has a specific gene change (MET exon 14 mutation). It is for people who have not had much or any prior treatment. The goal is to see if this medicine can shrink tumors and improve outcomes.
Guangzhou, GuangdongAges 18 years+ - NCT05989698Recruiting
Validating a wearable cough monitor (C-mo)
This study tests a wearable device (C-mo) that monitors coughing. It is for people of all ages who are currently coughing and can cooperate with wearing a small sensor on their belly for a short time.
AlfenaAges 2 years+ - NCT05990101Recruiting
Awake prone positioning for low oxygen in the ICU
This trial tests whether lying on your stomach (prone positioning) while awake can help you breathe better when you are in the ICU with low oxygen levels. It may reduce the need for a breathing tube.
KaunasAges 18 years+ - NCT05990348Recruiting
Comparing two breathing support methods for weaning from ventilator
This study compares two ways of helping patients breathe on a ventilator after a failed attempt to come off the machine. It looks at how the diaphragm and rib muscles work during each method to find the best approach for weaning.
RomeAges 18 years+ - NCT05991115Recruiting
Hospital to home study for children with asthma
This study helps families whose child is in the hospital for asthma. It aims to make the transition home smoother and reduce asthma-related health differences.
Washington D.C., District of ColumbiaAges 4–12 - NCT05991895Recruiting
Iruplinalkib for ALK-positive lung cancer
This real-world study looks at how effective Iruplinalkib is for people with ALK-positive non-small cell lung cancer. It is open to patients who have already taken this drug, and will simply collect data from your regular medical care.
Jinan, ShandongAges 18 years+ - NCT05992272Recruiting
How cues affect drinking and smoking habits
This study looks at how certain cues (like seeing a drink or a cigarette) trigger cravings and behavior in people who drink alcohol or smoke. Understanding this may help improve addiction treatments.
BerlinAges 16–65 - NCT05992324Recruiting
Testing lung ultrasound software for shortness of breath
This study is testing a software that helps doctors perform and interpret lung ultrasounds in patients with shortness of breath. The goal is to see how well the software works for identifying certain lung patterns called B-lines.
New Haven, ConnecticutAges 18 years+ - NCT05993364Recruiting
EFA treatment for brain injury recovery
This trial tests a treatment called EFA for people recovering from a brain injury (from trauma or stroke). It aims to help patients who are still in the early stages of recovery and can breathe on their own during the day.
Rovato, BSAges 18 years+ - NCT05996627RecruitingPhase 2
Belumosudil for early treatment of chronic graft-versus-host disease
This trial tests a pill called belumosudil to see if it can help people with chronic graft-versus-host disease (a common complication after a stem cell transplant where donor cells attack your body). It is for patients who have symptoms but are not yet on strong immune-suppressing drugs.
Duarte, CaliforniaAges 18 years+ - NCT05997719Recruiting
Study of EGFR-mutated lung cancer evolution and markers
This study looks at how EGFR-mutated lung cancer changes over time and tries to find markers that can predict how well you might respond to treatment. You will provide a tumor sample for genetic analysis.
GuanzhouAges 18 years+ - NCT05997602RecruitingPhase 2
Testing FCN-159 for children with LCH that returned
This trial tests a study drug, FCN-159, for children with a rare blood/immune disease called Langerhans cell histiocytosis (LCH) that has not responded to standard treatment or has come back. The goal is to see if this drug can shrink the LCH lesions and help the child feel better.
Beijing, Beijing MunicipalityAges 2–16 - NCT05998629Recruiting
Sweat sensor test for cystic fibrosis
This trial tests a new skin sensor that measures sweat to help diagnose cystic fibrosis. It compares results from people with CF and healthy volunteers to see if the device works accurately.
Hershey, PennsylvaniaAges 18–80 - NCT06000761Recruiting
Mouth care with human milk for premature babies
This trial is testing whether giving gentle mouth care with human milk to very premature babies in the NICU can help their health. It focuses on babies born early and with low birth weight whose mothers can provide milk.
Gainesville, FloridaAges 1 hour–3 days - NCT06001151RecruitingPhase 2
Cadonilimab plus chemo for PD-L1 negative lung cancer
This trial tests a new immunotherapy drug called cadonilimab combined with chemotherapy as a first treatment for people with advanced non-squamous non-small cell lung cancer that does not have the PD-L1 protein. The goal is to see if this combination works better than standard treatments.
Wuhan, HubeiAges 18–75 - NCT06001645Recruiting
Lung biomarkers and air leaks in severe lung injury
This study looks for markers in the blood and signs of air trapped in the lung tissue of people with acute respiratory distress syndrome (ARDS). It uses CT scans to understand why air leaks happen and if certain lab tests can predict them.
CagliariAges 18 years+ - NCT06002984Recruiting
Nerve monitoring during thyroid surgery to protect your voice
This study tests a device that monitors a nerve near your voice box during thyroid surgery. The goal is to help protect your voice by giving the surgeon live feedback on the nerve's location and function.
SeoulAges 19–79 - NCT06005246Recruiting
Munich ME/CFS Study for Young People
This study is tracking children, teens, and young adults (up to age 25) who developed ME/CFS after an infection. It aims to better understand the condition in younger people.
Munich, BavariaAges Up to 25 years - NCT06006390RecruitingPhase 1/Phase 2
CAR-T therapy for CEA-positive advanced solid tumors
This trial tests a new treatment called CAR-T cells that are designed to find and attack cancer cells carrying a protein called CEA. It is for people with advanced colorectal, esophageal, stomach, or pancreatic cancer who have already tried other treatments.
Taiyuan, ShanxiAges 18 years+ - NCT06006884Recruiting
Understanding long-term lung effects after COVID-19
This study looks at why some people develop long-term lung problems after COVID-19. It compares people who had severe COVID-19 and were hospitalized to those who had mild infections and recovered at home.
Rochester, MinnesotaAges 18 years+ - NCT06007261Recruiting
Testing a new microscope for lung cancer diagnosis
This study tests a new microscope that quickly analyzes lung tissue during a bronchoscopy or surgery. It may help doctors make faster, more accurate decisions about your care.
Nijmegen, GelderlandAges 18 years+ - NCT06007495Recruiting
Testing a new mask for carbon dioxide removal in breathing failure
This study tests a new mask designed to help remove carbon dioxide more effectively. It is for hospitalized adults with breathing failure who need non-invasive breathing support or high oxygen.
Montreal, QuebecAges 18 years+ - NCT06007547RecruitingPhase 4
Preventive surfactant therapy for preterm babies
This trial tests whether giving surfactant (a foam that helps lungs stay open) before breathing problems start can help very premature babies (born before 30 weeks) breathe better. It might reduce the need for a breathing tube.
Evanston, IllinoisAges Up to 15 minutes - NCT06008860RecruitingPhase 4
Astepro nasal spray for early COVID-19
This trial tests whether Astepro nasal spray can help people with mild or no COVID-19 symptoms recover faster. If you have tested positive and are vaccinated, you may qualify.
Chicago, IllinoisAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,637 recruiting pulmonology studies from the U.S. registry right now, out of 10,624 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.