Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,637 recruiting studies in this area right now.
By phase
- Not applicable4,308
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2309
- Phase 4208
- Phase 2/Phase 366
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Acute Respiratory Distress Syndrome72
- Chronic Obstructive Pulmonary Disease (COPD)72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona156
- Massachusetts128
- Florida116
- New York113
- Maryland111
- Texas90
- Pennsylvania83
- Illinois72
Recruiting studies6,637 total
- NCT06035120Recruiting
Sealing damaged lung parts in severe emphysema
This trial tests a new treatment called AeriSeal to seal off damaged parts of the lung in people with severe emphysema. It aims to help you breathe better by reducing the amount of air trapped in your lungs.
Phoenix, ArizonaAges 40–80 - NCT06035289Recruiting
Severe asthma registry for children and adults
This registry collects information about children and adults with severe asthma that is not well controlled with standard treatments. The goal is to better understand severe asthma and improve care.
AltdorfAges 6 years+ - NCT06036056Recruiting
Blood Chemistry Study in Mild ARDS
This study uses a special blood test (called NMR metabolomics) to understand how your body's chemistry changes in the early stages of mild ARDS. It may help find better ways to treat this serious lung condition.
Lucknow, Uttar PradeshAges 18–65 - NCT06036719Recruiting
Lung scarring study from childhood to old age
This trial looks at different types of lung scarring (called interstitial lung disease) to better understand the condition across all ages. It also includes family members of people with certain genetic mutations that affect the lungs.
Paris, Île-de-France RegionAges Any age - NCT06037083Recruiting
Checking stability after breathing tube removal in tiny preemies
This study looks at how stable extremely premature, very low-weight babies are after their breathing tube is removed for the first time. It aims to understand what helps these tiny infants breathe well on their own.
Montreal, QuebecAges Up to 6 months - NCT06037330RecruitingPhase 4
Study of nalbuphine for ARDS after surgery
This trial tests if the drug nalbuphine can help patients with acute respiratory distress syndrome (ARDS) after surgery. It aims to see if it improves breathing and pain while staying in the ICU.
Jinan, ShandongAges 18 years+ - NCT06037096Recruiting
Structured follow-up after pulmonary embolism
This study tests a structured follow-up program for people who have had a pulmonary embolism. The program aims to help you recover better after your clot and lower the chance of future problems.
AalborgAges 18 years+ - NCT06037941Recruiting
Breath test to check mesothelioma treatment response
This study is testing a special breath test (called an e-nose) to see if it can tell how well your treatment is working for malignant pleural mesothelioma. It is a non-invasive way to monitor your response to therapy.
Basking Ridge, New JerseyAges 30–85 - NCT06037967Recruiting
Studying biomarkers for allergies, asthma, and mast cell disorders
This trial collects blood and tissue samples to better understand allergies, asthma, and mast cell conditions. It aims to find markers that could improve diagnosis and treatment. Participation involves donating samples and sharing medical history.
ToulouseAges 18–100 - NCT06037954Recruiting
Mental health support for older adults with cancer
This study offers mental health care for older adults (65+) with breast, colorectal, lung, or prostate cancer who are getting treatment or recently finished. It aims to help people who are also feeling depressed.
New York, New YorkAges 65 years+ - NCT06038227Recruiting
Robotic vs. VATS surgery for early lung cancer
This study compares two types of minimally invasive surgery—robotic-assisted (da Vinci) and VATS—for people with early-stage non-small cell lung cancer. The goal is to see which approach might work better and help patients recover faster.
CopenhagenAges 18 years+ - NCT06038630RecruitingPhase 2
Xenon gas MRI study for lung and heart health
This study uses a special MRI scan (Xenon gas imaging) to look at how well your lungs and heart are working. It is for people with certain lung conditions, those getting blood transfusions or phlebotomy, or healthy volunteers.
Durham, North CarolinaAges 18 years+ - NCT06039631RecruitingPhase 2
Immuno-chemo before surgery and organ-sparing treatment for throat cancer
This trial tests whether adding immunotherapy before surgery, followed by either radiation or organ-preserving surgery, can improve outcomes for people with locally advanced laryngeal or hypopharyngeal cancer. It may help avoid complete removal of the voice box.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06039501Recruiting
The Family Perspectives Project Pilot Trial
This study looks at how to improve communication between families and the care team when a loved one is on a breathing machine in the intensive care unit. It may help families feel more supported and involved in care decisions.
Los Angeles, CaliforniaAges 18 years+ - NCT06040268RecruitingPhase 1/Phase 2
Advair study for HAPE risk and healthy volunteers
This trial tests if Advair HFA affects how likely someone is to develop High Altitude Pulmonary Edema (HAPE), a serious lung condition at high altitudes. It compares people who are prone to HAPE, those who are resistant, and healthy controls.
Aurora, ColoradoAges 18–50 - NCT06040541RecruitingPhase 1
Study of RMC-9805 for KRAS G12D solid tumors
This trial tests an experimental pill (RMC-9805) for people with solid tumors that have a specific KRAS G12D mutation. It's for those who have already tried other treatments and need new options.
Sacramento, CaliforniaAges 18 years+ - NCT06041776RecruitingPhase 3
Befotertinib after surgery for early-stage lung cancer with EGFR mutation
This trial tests if a targeted therapy pill (befotertinib) can lower the chance of cancer coming back after surgery for non-small cell lung cancer that has a specific EGFR mutation. You may be eligible if your tumor was completely removed and you have stage IB to IIIB disease.
BeijingAges 18 years+ - NCT06043440RecruitingPhase 2
Oxygen therapy for sleep apnea in Down syndrome
This study tests whether oxygen therapy can help children with Down syndrome who have sleep apnea. It compares oxygen treatment to no treatment to see if it improves breathing during sleep and thinking skills.
Los Angeles, CaliforniaAges 5–18 - NCT06043466RecruitingPhase 1
CAR-T cell therapy for CEA-positive advanced solid tumors
This trial tests a new cell therapy called CAR-T that targets cancer cells with a protein called CEA. It is for people with certain advanced cancers that have not responded to standard treatments.
Hangzhou, ZhejiangAges 18 years+ - NCT06044051Recruiting
Severe infant asthma and the lung microbiome study
This study looks at the bacteria (microbiome) in the airways of infants under 2 years old with severe asthma. It aims to understand how these bacteria might affect the disease.
RouenAges Up to 2 years - NCT06045338Recruiting
Mind-body program for long COVID symptoms
This trial tests a mind-body intervention to help people with ongoing long COVID symptoms like pain, fatigue, or brain fog. If you've had COVID-19 and have had symptoms at least 3 days a week for 3 months, this study might help.
Boston, MassachusettsAges 18–65 - NCT06045429RecruitingPhase 4
Mouth rinse for ICU patients on breathing machines
This trial tests if using a special mouthwash (3% hydrogen peroxide) can reduce bacteria in the lungs of ICU patients on breathing machines. It may help prevent infections in people who are already very sick.
PragueAges 18 years+ - NCT06045702Recruiting
Study of CFTR gene in epididymal cells from surgery
This study collects a small tissue sample from the epididymis during planned surgery. The sample is used to study how the CFTR gene works, which may help understand fertility problems in men with cystic fibrosis.
BrestAges 18 years+ - NCT06046248RecruitingPhase 2
Belumosudil and Rituximab for first-time chronic GVHD treatment
This trial tests a combination of two drugs, belumosudil and rituximab, as the first treatment for chronic graft-versus-host disease (cGVHD), a complication that can occur after a stem cell transplant. The goal is to see if this combination can control symptoms and reduce the need for steroids.
Atlanta, GeorgiaAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,637 recruiting pulmonology studies from the U.S. registry right now, out of 10,624 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.