Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,637 recruiting studies in this area right now.
By phase
- Not applicable4,308
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2309
- Phase 4208
- Phase 2/Phase 366
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Acute Respiratory Distress Syndrome72
- Chronic Obstructive Pulmonary Disease (COPD)72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona156
- Massachusetts128
- Florida116
- New York113
- Maryland111
- Texas90
- Pennsylvania83
- Illinois72
Recruiting studies6,637 total
- NCT06046495RecruitingPhase 1
Study of an oral EGFR inhibitor for non-small cell lung cancer
This trial tests PLB1004, an oral medication that targets a specific gene mutation (EGFR) in non-small cell lung cancer. It may be an option if you have this mutation and are looking for a new treatment.
Sacramento, CaliforniaAges 18 years+ - NCT06046547Recruiting
Palliative care learning for lung rehab patients
This trial tests adding palliative care education to pulmonary rehabilitation for people with COPD or ILD and their caregivers. It aims to see if this helps improve symptom management and quality of life.
AveiroAges 18 years+ - NCT06047301Recruiting
Pathways: A hope program for advanced lung cancer patients
This study tests a program called 'Pathways' that helps people with advanced lung cancer set personal goals, manage mental health, and improve quality of life. It's for those who are already receiving IV cancer treatment and are feeling some distress.
Lexington, KentuckyAges 18 years+ - NCT06047353Recruiting
Helping people with sleep apnea try PAP therapy for the first time
This study tests whether health advocates can help people with moderate-to-severe sleep apnea start using a PAP machine. If you've never used a PAP or other sleep apnea treatment before, this trial may help you get support and guidance.
Miami, FloridaAges 18–100 - NCT06047405Recruiting
Comparing two breathing machine settings for high carbon dioxide failure
This trial tests two different ways of setting a noninvasive breathing machine (BiPAP) to help patients with high carbon dioxide levels in the blood due to respiratory failure. It aims to find which setting works better for patients at Lenox Hill Hospital.
New York, New YorkAges 18 years+ - NCT06047496RecruitingEarly Phase 1
Time-restricted eating for sleep apnea
This study tests whether limiting your eating to a shorter daily window can improve health in people with untreated moderate to severe sleep apnea. You would eat all your meals within a set number of hours each day while tracking your progress on your smartphone.
La Jolla, CaliforniaAges 18–70 - NCT06049082RecruitingPhase 1
A study of KB408 for alpha-1 antitrypsin deficiency
This study tests a new gene therapy called KB408 for people with alpha-1 antitrypsin deficiency (AATD). It aims to see if KB408 can help your body produce enough of the missing protein to protect your lungs and liver.
Gainesville, FloridaAges 18–70 - NCT06051032Recruiting
Comparing balloon vs. suction for clotted dialysis fistulas
This study compares two ways to clear a sudden clot in a dialysis fistula (AVF). It uses either a balloon (to push the clot out) or a suction device (to pull the clot out) to restore blood flow.
Valencia, ValenciaAges 18 years+ - NCT06051513Recruiting
Testing colistimethate for CRE infection in hospitalized patients
This trial tests a medicine called colistimethate sodium for people in the hospital with a serious infection (pneumonia or bloodstream infection) caused by a resistant bacteria called CRE. The goal is to see if this antibiotic can effectively treat the infection.
Hefei, AnhuiAges 18–85 - NCT06051292Recruiting
Testing balloon size for lung pressure measurement in children
This study tests how much air to put in a small balloon in the esophagus (feeding tube-like device) to measure lung pressure more accurately. It is for children on a breathing machine whose settings are stable for the next 2 hours.
AydinAges 1 month–18 years - NCT06051695RecruitingPhase 1/Phase 2
CAR T cell therapy for mesothelin-positive solid tumors
This trial tests a new type of immune cell therapy (CAR T-cells) designed to target cancer cells that have a protein called mesothelin but have lost a marker that lets them hide from the immune system. It's for people with advanced solid tumors who have already tried standard treatments.
Gilbert, ArizonaAges 18 years+ - NCT06052098Recruiting
Comparing two ablation methods for early-stage lung cancer
This study compares two ways to destroy early-stage lung cancer without surgery: one using a needle through the chest (CT-guided) and another using a thin tube through the mouth (bronchoscopy-guided). It might be an option if you have small, outer-edge lung cancer and cannot or prefer not to have surgery.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06052436RecruitingPhase 1/Phase 2
Treg cell therapy for COVID-19 and acute respiratory distress
This trial tests a new cell therapy using Treg cells from thymic tissue to calm an overactive immune response in severe COVID-19 and ARDS. It aims to improve breathing and reduce inflammation.
Madrid, MadridAges 18–65 - NCT06053099Recruiting
Study of osimertinib after surgery for EGFR-mutated lung cancer
This trial collects data from people with early-stage lung cancer that has a common EGFR mutation. After complete surgical removal of the tumor, participants take osimertinib for 3 years and are followed regularly to see how well the treatment works and why resistance might develop.
AngersAges 18 years+ - NCT06053164RecruitingPhase 2
Portable oxygen for activity in mild-to-moderate lung disease
This study is testing whether using portable oxygen during physical activity can help people with mild-to-moderate interstitial lung disease feel better and be more active. It is for people whose oxygen levels drop during exercise but are normal at rest.
Edmonton, AlbertaAges 18–85 - NCT06053476Recruiting
Chest tube and pain care after lung surgery for collapsed lung
This study compares two ways to manage the chest tube and pain after surgery for a collapsed lung (pneumothorax). The goal is to find out which approach helps patients recover faster and with less pain.
VeldhovenAges 16 years+ - NCT06053580RecruitingPhase 2
Valsartan for pulmonary hypertension: protection study
This trial tests whether a blood pressure medicine called valsartan can help protect the lungs and heart in people with a specific type of pulmonary hypertension (Group 1 PAH). If you have PAH and are stable enough to walk 50 meters, you may be able to join.
Seattle, WashingtonAges 18–80 - NCT06053684Recruiting
Comparing two breathing machines for babies with bronchiolitis
This study tests if a new type of breathing machine (NAVA) works better than the standard machine for babies under 2 with severe bronchiolitis in the pediatric ICU. The goal is to see which machine helps babies breathe easier and avoid needing a breathing tube.
The Bronx, New YorkAges birth–2 years - NCT06054854Recruiting
Lung Cancer Biomarker Study (BIRD Biobank)
This study collects blood, tissue, and other samples from people with lung nodules, suspected lung cancer, or confirmed lung cancer to find better ways to diagnose and treat the disease. By joining, you help researchers discover new biomarkers that could improve care for future patients.
ToulouseAges 18 years+ - NCT06056999Recruiting
New method to identify lung nodule type
This study is testing a new method to help tell whether a lung nodule is benign (non-cancerous) or malignant (cancerous). It is for people who already need a biopsy or surgery for their lung nodule.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06057519RecruitingPhase 3
Optimized rifampicin dosing for TB
This trial tests whether higher or standard doses of the antibiotic rifampicin work better for treating pulmonary tuberculosis (a lung infection). You may benefit if you are starting TB treatment and have not had a bad reaction to rifampicin before.
TurinAges 18 years+ - NCT06057766Recruiting
Physical activity coaching after lung cancer surgery
This trial tests a coaching program to help you become more physically active after surgery for early-stage lung cancer. It may help you recover and improve your well-being.
Genk, LimburgAges 18 years+ - NCT06057935RecruitingPhase 2
Extra chemotherapy after surgery for peritoneal mesothelioma
This trial tests whether more chemotherapy after surgery can help people with a specific type of abdominal cancer (malignant peritoneal mesothelioma). It is for those who have had all visible tumor removed and have not had chemotherapy before.
Chicago, IllinoisAges 18 years+ - NCT06061562Recruiting
Sleep Apnea and Activity in Down Syndrome
This trial looks at whether physical activity can help improve sleep apnea in people with Down syndrome. It aims to find better ways to manage breathing problems during sleep.
La TroncheAges 6 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,637 recruiting pulmonology studies from the U.S. registry right now, out of 10,624 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.