Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,352 recruiting studies in this area right now.
By phase
- Not applicable4,048
- Phase 2834
- Phase 1460
- Phase 3421
- Phase 1/Phase 2312
- Phase 4213
- Phase 2/Phase 364
Top conditions
- Lung Cancer416
- Asthma194
- Non-Small Cell Lung Cancer182
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD134
- Breast Cancer111
- Pulmonary Hypertension105
- Colorectal Cancer89
- COVID-1988
- NSCLC87
- Chronic Obstructive Pulmonary Disease84
- Chronic Obstructive Pulmonary Disease (COPD)78
- Cystic Fibrosis77
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia68
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center33
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California385
- Alabama175
- Arizona154
- Florida121
- Massachusetts118
- Maryland115
- New York111
- Texas87
- Pennsylvania82
- Illinois73
Recruiting studies6,352 total
- NCT06242795RecruitingPhase 4
Hypertonic saline for non-cystic fibrosis bronchiectasis
This trial tests whether inhaling a saltwater solution (hypertonic saline) twice a day for 12 weeks can help people with bronchiectasis who have a chronic cough and have had flare-ups in the past. It aims to see if this treatment reduces mucus and improves quality of life.
Chapel Hill, North CarolinaAges 18 years+ - NCT04616313Recruiting
MRI and breathing tests in people who vape
This study uses a special lung scan (MRI) and breathing tests to understand how vaping affects lung structure and function. It may help researchers learn what early lung changes happen after starting vaping, even if you don’t feel sick.
London, OntarioAges 16 years+ - NCT05482022Recruiting
Test speaking valve effects for people with tracheostomy and brain injury
This study checks whether a speaking valve changes breathing, swallowing, and voice in people who have a tracheostomy after a brain injury. It may help doctors find safer ways to improve communication and function for people who are in a minimal conscious or unresponsive state.
RaananaAges 18 years+ - NCT06671613Recruiting
Fasting-mimicking diet with immunotherapy for advanced lung cancer
This study combines a special periodic diet that mimics fasting with the standard immunotherapy drug pembrolizumab (Keytruda) for people with advanced non-small cell lung cancer. The goal is to see if the diet can help the immunotherapy work better.
Long Beach, CaliforniaAges 18 years+ - NCT06681220RecruitingPhase 1/Phase 2
Temozolomide and stenoparib for relapsed small cell lung cancer
This trial tests two drugs—temozolomide and stenoparib—for people with small cell lung cancer that has returned after initial chemo. The goal is to see if this combination can shrink tumors or slow the cancer's growth.
Palo Alto, CaliforniaAges 18 years+ - NCT06676748RecruitingEarly Phase 1
Benzydamine gargle for sore throat after surgery
This trial tests whether a medicated mouthwash or gargle with benzydamine can help prevent a sore throat after surgery. It's for women having surgery with a type of breathing tube called a laryngeal mask airway.
SingaporeAges 21–80 - NCT06679257Recruiting
Liquid biopsy for lung transplant damage classification
This study tests a simple blood test (liquid biopsy) to detect and classify damage to a transplanted lung. It aims to find signs of rejection or injury earlier, which could help doctors treat problems sooner.
Gothenburg, Västra Götaland CountyAges 18 years+ - NCT06679972Enrolling by invitation
Impact of pregnancy liver condition on baby's breathing
This study looks at how a pregnancy liver condition (intrahepatic cholestasis) affects the baby's breathing after birth. It compares newborns whose mothers had this condition (and took medication for it) with newborns whose mothers did not have any liver issues during pregnancy.
Bucharest, BucharestAges 1 hour–4 weeks - NCT06674252Recruiting
Herbal treatment for symptoms after lung cancer surgery
This study tests whether a modified herbal formula (Bufei Decoction) can help reduce symptoms like cough, fatigue, and shortness of breath in older adults after lung cancer surgery, and whether it improves survival.
Beijing, Beijing MunicipalityAges 65 years+ - NCT06671015Recruiting
Comparing breathing support methods after a breathing tube is removed in people with heart failure
This study compares two types of breathing support—a high-flow nasal cannula and noninvasive ventilation—to see which one better prevents the need for re-inserting a breathing tube in people with systolic heart failure who are at high risk for breathing problems after the tube is removed.
New Haven, ConnecticutAges 18 years+ - NCT06677268Recruiting
Sleep and breathing rehab study for COPD patients
This study tests whether a respiratory rehabilitation program improves sleep quality in people with COPD. It may help you breathe better and sleep more restfully.
AmiensAges 50 years+ - NCT06673862Enrolling by invitation
Detecting fluid needs with a breathing machine change
This trial checks if a simple change in ventilator settings (a tidal volume challenge) can predict whether you need more fluids, compared to a standard fluid challenge. It's for patients on a breathing machine who have low blood flow.
Banhā, Al-QalyubiaAges 18 years+ - NCT06676956Recruiting
Testing robotic bronchoscopy with combining lymph node checks
This study is testing whether doing two different scope tests during the same procedure helps find lung cancer more quickly. The doctors will look at a lung nodule with a robot-assisted bronchoscope and also check nearby lymph nodes if they seem normal.
Sacramento, CaliforniaAges 18 years+ - NCT06680050RecruitingPhase 2
Study of radiation plus two drugs for advanced lung cancer after prior treatment
This trial tests whether adding two drugs, durvalumab and ceralasertib, after radiotherapy can help patients with stage III non-small cell lung cancer whose cancer has come back in the chest or spread to a few other spots after previous treatment with durvalumab. It aims to improve outcomes by boosting the immune system's ability to fight the cancer.
BresciaAges 18 years+ - NCT06680271Enrolling by invitation
Exercise program from home for older adults with heart or lung disease
This trial tests whether a home-based exercise program, guided remotely by a therapist, can help older adults with conditions like COPD, asthma, heart failure, or metabolic syndrome. The goal is to improve their health and quality of life without needing to go to a clinic.
Envigado, AntioquiaAges 60–100 - NCT06672081Recruiting
Early catheter treatment for high-risk pulmonary embolism
This study tests whether using a catheter (a thin tube) to remove blood clots from the lungs early can help people with a severe, life-threatening pulmonary embolism. It is for patients who are in shock or have had a cardiac arrest due to a large clot.
Bad KrozingenAges 18 years+ - NCT06675045Recruiting
High flow oxygen therapy and breathing patterns
This study looks at how breathing changes in patients with low blood oxygen levels who are treated with high-flow oxygen through a mask. It aims to understand which patients might need a breathing tube.
MarseilleAges 18 years+ - NCT06673329RecruitingPhase 1
Brodalumab for immune-related side effects from cancer treatment
This trial tests if brodalumab, an antibody that blocks a specific immune pathway (IL-17), can help control side effects caused by immunotherapy cancer treatment. It is for people with advanced solid organ cancers who have immune-related side effects that are suspected to involve IL-17.
New York, New YorkAges 18 years+ - NCT06670443Recruiting
Electrical stimulation for COPD breathing and leg muscles
This trial tests if electrical stimulation can help people with COPD strengthen both their breathing and leg muscles. It may improve your ability to move and breathe more easily.
DokkiAges 40–65 - NCT06669897Recruiting
Cough severity questionnaire study
This study is testing a new questionnaire to measure how severe a cough is. It is looking for people with a chronic cough (cough lasting a long time) and healthy volunteers to see if the questionnaire works well.
Badalona, BarcelonaAges 30–99 - NCT06677151Recruiting
New sleep apnea device study for CPAP users
This study tests a new device for sleep apnea that you can use instead of a CPAP machine. If you have moderate to severe sleep apnea and CPAP isn't working well for you, this study may help find an easier option.
Ann Arbor, MichiganAges 18 years+ - NCT06670833Recruiting
Tools to improve childhood pneumonia care
This trial tests new tools to help doctors diagnose and manage pneumonia in children. It may help children with cough or trouble breathing who are not severely ill.
Dakar, DakarAges 2 months–12 years - NCT06670521RecruitingPhase 2
Steroids for swallowing problems after breathing tube removal
This trial tests a steroid medication (corticosteroids) to reduce swelling in the voice box after a breathing tube is taken out. It may help improve swallowing and reduce the risk of food or drink going into the lungs.
Aurora, ColoradoAges 18 years+ - NCT06676644Recruiting
Flu vaccine with booster for older adults with health conditions
This trial tests whether a flu vaccine with an extra ingredient (called an adjuvant) is safer and works better for older Asian adults with chronic health conditions than a standard flu vaccine. It aims to provide better protection against the flu for people like you.
TaipeiAges 65 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,352 recruiting pulmonology studies from the U.S. registry right now, out of 10,005 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.