Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,352 recruiting studies in this area right now.
By phase
- Not applicable4,048
- Phase 2834
- Phase 1460
- Phase 3421
- Phase 1/Phase 2312
- Phase 4213
- Phase 2/Phase 364
Top conditions
- Lung Cancer416
- Asthma194
- Non-Small Cell Lung Cancer182
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD134
- Breast Cancer111
- Pulmonary Hypertension105
- Colorectal Cancer89
- COVID-1988
- NSCLC87
- Chronic Obstructive Pulmonary Disease84
- Chronic Obstructive Pulmonary Disease (COPD)78
- Cystic Fibrosis77
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia68
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center33
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California385
- Alabama175
- Arizona154
- Florida121
- Massachusetts118
- Maryland115
- New York111
- Texas87
- Pennsylvania82
- Illinois73
Recruiting studies6,352 total
- NCT06686771RecruitingPhase 3
Radiation for limited growth in advanced lung cancer on immunotherapy
This trial tests whether giving high-precision radiation to a few spots that are growing during immunotherapy (with or without chemotherapy) can help people with advanced lung cancer. It aims to see if treating these limited areas of resistance can extend the time the cancer stays under control.
Phoenix, ArizonaAges 18 years+ - NCT05045612RecruitingPhase 4
Antibiotics for certain viral lung infections in hospitalized adults
This trial studies whether giving antibiotics affects recovery in adults hospitalized with moderately severe infections caused by specific viruses (influenza, parainfluenza, RSV, or hMPV). It may help show when antibiotics are helpful or unnecessary for viral airway illness.
BergenAges 18 years+ - NCT06001645Recruiting
Lung biomarkers and air leaks in severe lung injury
This study looks for markers in the blood and signs of air trapped in the lung tissue of people with acute respiratory distress syndrome (ARDS). It uses CT scans to understand why air leaks happen and if certain lab tests can predict them.
CagliariAges 18 years+ - NCT06690203Enrolling by invitation
Herbal Medicine for Chronic Lung Conditions (NRICM102)
This trial tests an herbal medicine called NRICM102 for people with chronic cough and long-term lung diseases like asthma or COPD. It aims to see if the medicine is safe and helps improve symptoms.
Taichung, No.1650, Taiwan Boulevard Sect. 4Ages 18 years+ - NCT06692400Recruiting
Suctioning, pain, and blood markers in intubated patients
This study looks at how routine suctioning of the breathing tube affects pain levels and certain substances in the blood in adults who are on a breathing machine for serious infections like flu, pneumonia, COVID, or sepsis. It may help doctors better understand and manage your comfort during this procedure.
Loma Linda, CaliforniaAges 18 years+ - NCT06682832Recruiting
Comparing lung health in COPD and PRISm patients
This study compares how people with COPD, those with a lung condition called PRISm (Preserved Ratio Impaired Spirometry), and healthy individuals feel and function. It aims to understand differences in symptoms and daily life.
AnkaraAges 40 years+ - NCT06687408Recruiting
Minimally invasive sleeve lobectomy for lung cancer
This study looks at a type of lung cancer surgery called sleeve lobectomy done with small incisions (minimally invasive). It aims to see if this approach is safe and effective for people with non-small cell lung cancer that requires removing a part of the lung and reconnecting the airway.
HangzhouAges 18 years+ - NCT06691464Enrolling by invitation
Using FAPI PET/CT to find lung scarring in non-healing ARDS
This study uses a special PET/CT scan to look for active scar tissue (fibrosis) in the lungs of people who are still very sick with ARDS after 5 days of ventilator support. It may help doctors understand why some lungs don't heal and could guide future treatments.
Groningen, Provincie GroningenAges 20 years+ - NCT06691971Recruiting
Testing a device that detects wheezing in asthma attacks
This study is testing a device called AeviceMD that listens for wheezing—a whistling sound when breathing—to help doctors quickly spot asthma attacks. If you or your child is in the emergency room with a sudden asthma flare-up, you may be able to join.
The Bronx, New YorkAges 3 years+ - NCT06683599Recruiting
Oxygen via nasal tube for babies during breathing tube placement
This study tests whether giving extra oxygen through a small tube in the nose during placement of a breathing tube helps young children stay safer. It is for newborns and infants up to about 1 year old who need a breathing tube for surgery or other non-emergency procedures.
Perth, Western AustraliaAges 1 minute–12 months - NCT06686251Recruiting
AI assistant for reading chest X-rays in breathing problems
This study tests a computer program that helps doctors read chest X-rays faster and more accurately. It is for adults who had an X-ray because of breathing problems like a cough or fever.
Curitiba, ParanáAges 18 years+ - NCT06690216Enrolling by invitationPhase 1/Phase 2
PET scan study for PD-L1 in certain cancers
This trial tests a new PET imaging agent, [18F]AlF-NOTA-PCP2, to detect PD-L1 protein in tumors. It may help guide treatment decisions for people with glioblastoma, head and neck, lung, or esophageal cancer.
Jinan, ShandongAges 18 years+ - NCT06687863Enrolling by invitation
Exercise and genes in high blood pressure with sleep apnea
This study looks at how exercise and your genes affect blood pressure in people with both high blood pressure and obstructive sleep apnea (a condition where breathing stops briefly during sleep). It aims to see if a tailored exercise program can help you better control your blood pressure.
São Paulo, São PauloAges 45–70 - NCT06688422Recruiting
Using a breathing device during lung cancer treatment
This trial tests if using a simple breathing exercise device (called an incentive spirometer) during chemo and radiation for advanced lung cancer can help improve breathing outcomes and overall recovery.
Camden, New JerseyAges 18 years+ - NCT06683092Recruiting
Restarting triple therapy with close monitoring for side effects
This trial tests whether carefully restarting a triple-combination CFTR modulator (VTD) is safe and helpful for people with cystic fibrosis who had to stop or change Trikafta because of mental health side effects or liver injury. You will be closely monitored with surveys and daily diaries to ensure your safety.
Birmingham, AlabamaAges 6 years+ - NCT06382883Recruiting
Lifestyle and activity for sleep apnea
This study tests a lifestyle and physical activity program as a treatment for obstructive sleep apnea. It is for people who have not tried CPAP and want to see if exercise and healthy habits can help.
JyväskyläAges 18–70 - NCT06412172Recruiting
Natural history study of lung papillomatosis
This study is for people with HPV-related recurrent respiratory papillomatosis (RRP) that has spread to the lungs. Doctors will follow your health over time and study the condition to learn more about how it progresses.
New Haven, ConnecticutAges 18–99 - NCT06687941RecruitingPhase 1
Trial of AST-201 for GPC3-positive advanced solid tumors
This trial tests a new drug called AST-201 for people with advanced solid tumors that have a specific protein (GPC3). The study aims to see how safe and well-tolerated the drug is, and how the body processes it.
Goyang-si, Gyeonggi-doAges 19 years+ - NCT06684379RecruitingPhase 1/Phase 2
Two Doses of PRS CK STORM for Severe Viral Pneumonia
This study tests a new drug called PRS CK STORM to see if it can safely calm the body's overactive immune response (cytokine storm) in people with severe pneumonia from COVID-19, flu, or RSV who need oxygen. It aims to reduce inflammation and improve recovery.
Alcalá de Henares, MadridAges 18 years+ - NCT06682793RecruitingPhase 1/Phase 2
Study of A2B395 therapy for solid tumors with EGFR and HLA loss
This trial tests a new cell therapy called A2B395 for cancers that have EGFR, a protein on the cell surface, and have lost a specific marker called HLA-A*02. The therapy uses specially engineered immune cells to target and kill these cancer cells. This may help patients with colorectal, lung, head and neck, breast, kidney, or other solid tumors that are no longer responding to standard treatments.
Gilbert, ArizonaAges 18 years+ - NCT06693336RecruitingPhase 2
Paclitaxel wafer during lung cancer surgery
This study tests a new way of giving paclitaxel—a chemotherapy drug—directly into the chest during lung cancer surgery. It aims to reduce the chance of cancer coming back after surgery, and may have fewer side effects than standard IV chemo.
Rochester, MinnesotaAges 18–80 - NCT06692738RecruitingPhase 3
Is a new immunotherapy better than Keytruda for squamous lung cancer?
This trial tests a new drug called Rilvegostomig against the standard drug pembrolizumab (Keytruda), both combined with chemotherapy, as a first treatment for advanced squamous non-small cell lung cancer. It aims to see which combination works better.
Tucson, ArizonaAges 18 years+ - NCT06689488Recruiting
Microwave ablation for lung cancer via bronchoscopy
This study tests a new, less invasive way to treat lung cancer using microwave energy delivered through a thin tube inserted into the airway. It is for people with small, confirmed lung tumors who are already being considered for surgery, and who cannot or prefer not to have blood thinners.
Amsterdam, The NetherlandsAges 18 years+ - NCT06634979Recruiting
Selective lymph node removal for small lung cancers
This trial compares removing fewer lymph nodes during surgery for early-stage non-small cell lung cancer. It is for people with a small tumor (2 cm or less) that has both solid and ground-glass parts.
ShanghaiAges 18–80
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,352 recruiting pulmonology studies from the U.S. registry right now, out of 10,005 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.