Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,643 recruiting studies in this area right now.
By phase
- Not applicable4,313
- Phase 2851
- Phase 1471
- Phase 3424
- Phase 1/Phase 2309
- Phase 4209
- Phase 2/Phase 366
Top conditions
- Lung Cancer425
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD142
- Breast Cancer111
- COVID-19107
- Pulmonary Hypertension101
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Interstitial Lung Disease79
- Pneumonia79
- Cystic Fibrosis78
- Chronic Obstructive Pulmonary Disease (COPD)73
- Acute Respiratory Distress Syndrome72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca64
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona155
- Massachusetts128
- Florida116
- New York113
- Maryland111
- Texas91
- Pennsylvania82
- Illinois72
Recruiting studies6,643 total
- NCT03142022Recruiting
Sleep breathing study after lung transplant
This study checks sleep-related breathing problems (like pauses in breathing during sleep) in people about a year after a lung transplant. It uses a sleep test to understand what’s happening and may help guide better follow-up care.
LeuvenAges 18 years+ - NCT03318406Recruiting
Registry for patients with uneven emphysema lung damage
This study follows people with uneven emphysema to better understand outcomes and safety after treatment. If you qualify, you’ll share health information and may undergo lung imaging before and after treatment.
ViennaAges 18 years+ - NCT03161808Recruiting
CF rare mutation blood and tissue sample collection study
This study collects cells from people with cystic fibrosis (CF) caused by rare CFTR gene changes. The goal is to build a cell bank for future research, which may help scientists develop better tests and treatments for rare CF types.
Birmingham, AlabamaAges 17 years+ - NCT03035097Recruiting
Study of lung illness for people who served in Southwest Asia
This study is building a research database and stored samples from people who served in the Southwest Asia wars. It may help researchers learn what causes lung problems in veterans and how to better diagnose or treat them.
Denver, ColoradoAges 18 years+ - NCT03093116RecruitingPhase 1/Phase 2
Repotrectinib for ALK, ROS1, or NTRK tumor gene changes
This trial studies repotrectinib, a targeted medicine, in people with advanced solid tumors that have specific gene rearrangements (ALK, ROS1, or NTRK). It may help shrink tumors or control cancer growth based on the patient’s tumor genetic result.
Duarte, CaliforniaAges 12 years+ - NCT03329274Recruiting
Histiocytosis patient registry for Erdheim-Chester and related diseases
This is a registry (a research database) for people with Erdheim-Chester disease and other related “histiocytosis” conditions. It collects past and future medical information to better understand these illnesses and support future research.
New York, New YorkAges 18 years+ - NCT03368092RecruitingPhase 3
Inhaled medication to prevent lung failure after severe trauma
This trial tests whether inhaled dornase alfa can reduce the risk of respiratory (lung) failure in adults with severe trauma who are on a breathing machine in the ICU. If it works, it may help patients spend less time with dangerous breathing complications.
StrasbourgAges 18 years+ - NCT03387865Recruiting
Lung cancer database study for newly diagnosed patients
This study builds a detailed lung-cancer database by collecting clinical and lab information from people newly diagnosed. It aims to help doctors better understand lung cancer and how patients are treated from the start.
LilleAges Any age - NCT03303586Recruiting
Compression stockings to improve nighttime asthma symptoms
This study tests whether wearing compression stockings at night can reduce asthma symptoms during sleep. It may help some people notice fewer nighttime breathing problems.
Toronto, OntarioAges 20–75 - NCT02986087Recruiting
FETO balloon procedure for severe congenital diaphragmatic hernia
This trial studies a fetal procedure called FETO (placing a small balloon in the baby’s windpipe) to help severe congenital diaphragmatic hernia babies develop better lungs before birth. It may help some babies whose scans suggest very limited lung growth, but it requires specific timing and pregnancy conditions.
Cincinnati, OhioAges 18–50 - NCT03093688RecruitingPhase 1/Phase 2
Testing an immune-cell infusion for advanced solid tumors
This trial tests whether adding special immune cells (iNKT cells and CD8+ T cells) given by IV infusion can help treat advanced cancers. It mainly looks at safety first, and also checks whether the treatment can shrink or control cancer.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT03290534RecruitingPhase 2
Implantable radiation sheet for early-stage lung cancer
This Phase 2 study tests whether a permanently implanted, low-dose radiation “sheet” can be used to treat certain early-stage lung cancers. It may help shrink or control tumors while delivering radiation directly at the cancer site.
New York, New YorkAges 18 years+ - NCT03014609Recruiting
Testing cardiovascular risk in people with COPD
This trial studies cardiovascular (heart and blood vessel) risk in people who have stable COPD or a recent worsening of COPD. It may help researchers understand which risks to monitor during and after a COPD flare and how to prevent complications.
Grenoble, La TroncheAges 18–85 - NCT03323112Recruiting
Studying immune responses to seasonal flu shots in health workers
This study looks at how your immune system (your body’s infection-fighting system) responds after you get the seasonal flu vaccine. It may help researchers understand what the vaccine triggers in people working in healthcare and labs.
HelsinkiAges 18–64 - NCT03041805Recruiting
Check whether a clot-risk score predicts recovery after vein surgery
This study looks at how well a clot-risk score (Caprini score) relates to blood clot checks and outcomes after varicose vein surgery. You may be asked to have an ultrasound scan a few weeks after your operation and be followed for about 4 weeks.
MoscowAges 18 years+ - NCT03192501Recruiting
Using prior scans to guide cancer treatment choices
This trial tests whether using existing “PACS” scan images to guide individualized cancer treatment (compared with standard care) can improve outcomes for people with advanced or metastatic cancer. It may help doctors make more precise treatment decisions using your past imaging.
Guangzhou, GuangdongAges 18–70 - NCT03307330Recruiting
Study of body fat in people with obstructive sleep apnea
This study looks at how body fat (“adipose tissue”) may differ in people with obstructive sleep apnea. You may be asked for consent and could be asked to stop certain medicines short-term so researchers can take a safe fat sample.
Rochester, MinnesotaAges 18–60 - NCT02947945RecruitingPhase 2
Reslizumab for EGPA in adults
This trial tests reslizumab, a medicine that targets a specific immune signal, to improve symptoms in people with eosinophilic granulomatosis with polyangiitis (EGPA). It may help lower disease activity and reduce inflammation-related problems.
Denver, ColoradoAges 18 years+ - NCT03138863Recruiting
FETO surgery to help a baby’s lungs in left diaphragmatic hernia
This trial studies a specialized pregnancy procedure (FETO) done to help babies with a defect in the diaphragm called congenital diaphragmatic hernia (CDH) grow better lungs before birth. It may help by improving lung development, based on how severe the baby’s lung underdevelopment looks on ultrasound, and it requires close follow-up at the study hospital.
Miami, FloridaAges 18–50 - NCT06534359Recruiting
Gastric vs transpyloric feeding for BPD
This study compares two ways of feeding premature babies with lung disease (BPD) who still need breathing support: feeding through a tube into the stomach (gastric) versus past the stomach into the small intestine (transpyloric). The goal is to see which feeding method helps these babies grow better and avoid problems.
Palo Alto, CaliforniaAges 1 month–1 year - NCT07245888Recruiting
Studying pneumonia in ventilated ICU patients
This study looks at different types of lung infections in ICU patients on breathing machines. By analyzing fluid from your lungs, researchers hope to better understand pneumonia and improve treatment.
LimogesAges 18 years+ - NCT07244835RecruitingPhase 1
A study of DEG6498 for advanced solid tumors
This trial tests a new drug, DEG6498, for people with advanced solid tumors that have not responded to other treatments. It may be an option if your cancer has a BRAF mutation or is a type of liver cancer called HCC.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07262541Recruiting
Measuring airway opening pressure in children on ventilators
This study tests a simple way to measure the pressure needed to open the airways in children on a breathing machine. It may help doctors provide better breathing support for your child in the intensive care unit.
ParisAges Up to 17 years - NCT07674953Recruiting
CPAP and oxygen delivery in preterm infants
This study looks at how different levels of CPAP (a breathing machine that helps keep the lungs open) affect oxygen delivery and lung expansion in preterm babies. It may help doctors understand the best settings for infants who need breathing support.
Little Rock, ArkansasAges Any age
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,643 recruiting pulmonology studies from the U.S. registry right now, out of 10,656 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.