Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,780 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1251
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease339
- Autism Spectrum Disorder240
- Dementia227
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder142
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Suicidal Ideation89
- Mild Cognitive Impairment (MCI)88
Leading sponsors
- VA Office of Research and Development105
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- The University of Hong Kong51
- Karolinska Institutet50
Where studies are running
- California520
- Massachusetts267
- New York256
- Texas209
- Maryland176
- Pennsylvania171
- Florida149
- Alabama118
- Arizona108
- Illinois104
Recruiting studies7,780 total
- NCT06956300Recruiting
TMS to help with thinking and memory in aging
This study uses a noninvasive brain stimulation technique called TMS to see if it can slow cognitive decline in older adults who are healthy or have very early signs of Alzheimer's disease. It aims to improve memory and thinking.
Boston, MassachusettsAges 40–99 - NCT06958406Recruiting
Brain-heart connection after head injury
This study uses brain scans (MRI) to understand how a traumatic brain injury can affect the heart. It may help find better ways to treat the brain-heart connection after a head injury.
ShanghaiAges 18–80 - NCT06954025Enrolling by invitationPhase 2
MDMA therapy for PTSD inpatients
This trial tests whether high-dose MDMA, given during intensive inpatient therapy, can help people with PTSD that hasn't improved with other treatments. It takes place at a specialized trauma center and involves several therapy sessions with the drug.
OegstgeestAges 18 years+ - NCT06959992Recruiting
Resilience in transgender and nonbinary people in the metaverse
This study explores how transgender and nonbinary people handle social challenges and build resilience in virtual worlds (the metaverse). It aims to understand the impact of online experiences and may help develop better support programs.
Bucharest, BucharestAges 18–35 - NCT06957418RecruitingPhase 2
Alzheimer's tau drug study for early stage patients
This trial tests a treatment targeting tau protein buildup in the brain for people with early Alzheimer's. You may join if you have memory or thinking changes but are still living independently, and brain scans show both amyloid and tau clumps.
San Francisco, CaliforniaAges 50–80 - NCT06961916Recruiting
Brain stimulation to improve connections in schizophrenia
This study tests whether a non-invasive brain stimulation technique called TMS can improve brain connections in people with schizophrenia. It involves two types of MRI scans and several TMS sessions to see if it can help with thinking and symptoms.
Houston, TexasAges 18–60 - NCT06959303Enrolling by invitation
Teach-Back Method in Angiography Study
This study tests whether a 'teach-back' method (where you repeat back what you learned) helps patients understand their care before and after angiography, a heart procedure. It aims to improve how well you know important health information.
MersinAges 18 years+ - NCT06960980Recruiting
Virtual reality driving program for teens with ADHD
This study tests whether a virtual reality driving program can help teens with ADHD become safer drivers. It is for teens aged 16-19 who have a license, drive unsupervised, and have a parent or guardian willing to take part.
Cincinnati, OhioAges 16–19 - NCT06955195Recruiting
Youth mental wellness support for Hong Kong students
This study looks at ways to support the mental wellness of young people in Hong Kong secondary schools. It is for students in Form 1 to Form 3 and involves helping teens help each other.
Hong Kong, HONG KONGAges Any age - NCT06953596Recruiting
TMS for prolonged grief after a loss
This study is testing if a treatment called TMS (transcranial magnetic stimulation, a non-invasive brain stimulation technique) can help people who are struggling with intense, long-lasting grief after losing a loved one. If you have been feeling stuck in your grief for a long time, this might be an option to explore.
Ottawa, OntarioAges 18 years+ - NCT06962111Recruiting
Partner in Care Living Alone Plus study for early-stage dementia
This study tests a workshop to help people with early-stage memory problems who live alone. If you have mild dementia or mild cognitive impairment and can join Zoom sessions, you may be eligible.
Phoenix, ArizonaAges 60 years+ - NCT06956781Recruiting
Finding the best treatment for childhood PTSD
This study tests different ways to help children ages 8-17 who have PTSD after a traumatic event. It looks at how to best support both the child and their caregiver through therapy and surveys.
Rochester, New YorkAges 8–17 - NCT06953687Recruiting
Shared decision making for PTSD treatment in active duty military
This trial tests a shared decision-making approach to help active duty military members with PTSD choose the best treatment for them. You and your doctor will work together to decide on a plan that fits your needs and values.
Fort Hood, TexasAges 18 years+ - NCT06954402Recruiting
Resilience study for people with opioid use disorder
This study looks at resilience in people with opioid use disorder. Researchers want to understand what helps people stay strong and recover. You may be able to join if you are currently using opioids or receiving treatment.
Baltimore, MarylandAges 18 years+ - NCT06956352Enrolling by invitation
Study on better care for pregnant women with opioid use disorder
This study tests a team-based approach to help pregnant women with opioid use disorder get better support during pregnancy. It may improve care for mothers and babies.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06953167Recruiting
Dementia study for older adults with prior brain checks
This study follows older adults who have already had amyloid testing, to track changes in memory and thinking over time. It helps researchers understand how to prevent dementia.
LondonAges 65 years+ - NCT06961591Recruiting
Cooking skills for long-term weight loss in young adults with ID
This program teaches cooking skills to help young adults with intellectual disabilities lose weight and keep it off for 2 years. You’ll learn to prepare healthier meals with support from a family member or caregiver.
Kansas City, KansasAges 18–35 - NCT06959212Recruiting
Memory study in patients with disorders of consciousness
This trial studies memory abilities in people who are unconscious due to a brain injury. It compares unconscious patients, conscious patients in intensive care, and people who have recovered consciousness after being unconscious. Participation involves memory testing and may help us understand how the brain recovers.
ParisAges 15 years+ - NCT06960083Recruiting
TMS therapy for sound sensitivity (misophonia)
This trial tests if magnetic brain stimulation (TMS) can reduce the intense anger or fear triggered by certain sounds. It's for adults who feel very distressed by specific noises.
New York, New YorkAges 18–55 - NCT06957392Recruiting
Study on gaming and social rewards in internet gaming disorder
This trial looks at how social rewards affect thinking and control in people with internet gaming disorder. It may help find better ways to help those who spend a lot of time playing Honor of Kings.
BengbuAges 18–35 - NCT06957808Recruiting
Diroximel fumarate brain health study for schizophrenia
This trial tests if a drug called diroximel fumarate can help increase a natural antioxidant (glutathione) in the brain for people with schizophrenia. It aims to see if lowering inflammation and boosting brain protection might improve symptoms.
London, Greater LondonAges 18–65 - NCT06952933Recruiting
Trauma and resilience in adults with congenital heart disease
This study surveys adults with congenital heart disease to understand how psychological trauma and resilience affect their health. You would complete online questionnaires about your experiences and coping.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06961058Recruiting
Telehealth vs. in-person follow-up for opioid addiction treatment
This study compares follow-up care after an emergency department visit for opioid addiction: either through telehealth (video visits) or in-person appointments. The goal is to see which method helps people stay in treatment after they leave the ED.
El Centro, CaliforniaAges 18 years+ - NCT05319509Recruiting
Virtual reality therapy for anxiety in public health students
This pilot study tests whether guided virtual reality sessions can reduce anxiety symptoms in eligible students. You may be asked to complete brief anxiety screening and use the VR therapy if you qualify.
Houston, TexasAges 18–30
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,780 recruiting psychiatry studies from the U.S. registry right now, out of 12,430 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.