Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,780 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1251
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease339
- Autism Spectrum Disorder240
- Dementia227
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder142
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Suicidal Ideation89
- Mild Cognitive Impairment (MCI)88
Leading sponsors
- VA Office of Research and Development105
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- The University of Hong Kong51
- Karolinska Institutet50
Where studies are running
- California520
- Massachusetts267
- New York256
- Texas209
- Maryland176
- Pennsylvania171
- Florida149
- Alabama118
- Arizona108
- Illinois104
Recruiting studies7,780 total
- NCT06972368Recruiting
Home brain stimulation for depression in borderline personality disorder
This trial tests whether a gentle brain stimulation device (tDCS) used at home can help with depression in people with borderline personality disorder. If you have BPD and current depression, you may be able to participate from home using your smartphone.
Montreal, QuebecAges 18–65 - NCT06969170RecruitingPhase 2
Psilocybin oral solution for generalized anxiety disorder trial
This study tests a psilocybin oral solution in adults with generalized anxiety disorder (GAD). It aims to see if the drug is safe, tolerable, and helpful for reducing anxiety symptoms.
Kingston, OntarioAges 18–60 - NCT06965010Enrolling by invitation
Tracking Care in Opioid Treatment Programs
This study tests whether tracking your progress with regular check-ins (measurement-based care) helps improve treatment for people starting medication for opioid use disorder at a treatment program.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06965686Recruiting
A support program for menopause and dementia risk
This trial tests a personalized support program for people going through menopause who have a higher risk of dementia. The program aims to help with emotional well-being and reduce dementia risk.
Chicago, IllinoisAges 40–58 - NCT06969521Recruiting
Online speech therapy for kids who struggle with the R sound
This trial tests a new online treatment program designed to help children and teens improve their production of the R sound. It may be a good option if your child has difficulty saying the R sound and speaks English as their main language.
Montclair, New JerseyAges 8–17 - NCT06969365Enrolling by invitationPhase 1
Weighted blankets for IUD insertion comfort
This trial tests if using a weighted blanket during IUD placement can help reduce pain or anxiety. It's for people who are scheduled to get an IUD and are at least 18 years old.
Kansas City, MissouriAges 18 years+ - NCT06962527Recruiting
Study on how the brain handles uncertainty
This study uses brain imaging to understand how people react to uncertain situations. It may help develop better ways to treat anxiety and related conditions.
Chicago, IllinoisAges 25–60 - NCT06969755RecruitingPhase 4
Brain scans and genetics to guide early schizophrenia treatment
This study tests whether using brain scans and genetic tests can help choose the best treatment for people early in their schizophrenia. It will check if these biomarkers can predict who will respond better to medication.
Birmingham, AlabamaAges 18–35 - NCT06962592Recruiting
Mentor Moms+ pregnancy alcohol support study
This study tests whether having a mentor mom can help people who are pregnant and have used alcohol recently. It aims to provide support and improve health for both the parent and baby.
Cape Town, Western CapeAges 16 years+ - NCT06963801Recruiting
DBT for emotional challenges during pregnancy
This study tests whether a therapy called Dialectical Behavior Therapy (DBT) can help pregnant people who struggle with strong emotions. If you are at least 12 weeks pregnant and find it hard to manage your feelings, you may be able to join.
Durham, North CarolinaAges 18–45 - NCT06963463Recruiting
Sleep & light therapy for teens with depression
This study tests a program that combines sleep and light therapy to help teens with depression and sleep problems feel better. It focuses on improving your sleep schedule and adding bright light exposure to boost mood.
Philadelphia, PennsylvaniaAges 12–18 - NCT02811510RecruitingPhase 1
Study of THC effects on people with past cannabis use
This Phase 1 study tests how THC (the main active ingredient in cannabis) affects healthy adults, and whether effects differ by gender. It’s designed to learn about short-term body and brain responses to THC.
West Haven, ConnecticutAges 18–55 - NCT04596592Recruiting
Puberty blockers and estradiol effects on heart health
This study looks at how puberty blockers and then estradiol (estrogen) may affect heart and metabolism health in teens. It may help doctors understand risks and benefits for transgender youth starting gender-affirming hormone care.
Aurora, ColoradoAges 13–16 - NCT05993754Recruiting
Preventing confusion after surgery in frail older adults
This study tests whether a special nursing care plan can help prevent confusion after surgery in older adults who are frail. If you are 65 or older, having planned surgery, and generally healthy enough, this trial may be an option.
Santiago, Santiago MetropolitanAges 65 years+ - NCT06369714Recruiting
Brain-training video game for ADHD in children
This trial tests a digital therapy that uses neurofeedback (brainwave training) to help children with ADHD improve focus and attention. It's designed for kids ages 6 to 11 who haven't had ADHD treatment in the last month.
Shanghai, Shanghai MunicipalityAges 6–12 - NCT06604481Recruiting
Online coaching for family caregivers
This study tests a 6-week online coaching program to help family caregivers reduce stress and build resilience. You'll learn practical strategies you can use at home.
Hong KongAges 18 years+ - NCT05955001RecruitingPhase 2/Phase 3
Tadalafil for early urinary symptoms after prostate surgery
This trial studies whether daily tadalafil (5 mg) can improve early urinary trouble and erection function after endoscopic prostate tissue removal. It may help men whose urinary symptoms continued even after prior medicine.
Al Mansurah, Dakahlia GovernorateAges 40–80 - NCT06957067Recruiting
PTSD Therapy Switch Study for Veterans
This study tests whether switching PTSD therapies or staying with one approach works better for veterans. It aims to reduce dropout and improve mental health outcomes.
Phoenix, ArizonaAges 18 years+ - NCT06958523Recruiting
Apple Health Study for US iPhone users
This study uses your iPhone and optional devices like Apple Watch to collect health data over time. It aims to discover how technology can help monitor and improve health.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06961968RecruitingPhase 3
Schizophrenia medication withdrawal study
This study tests whether patients with schizophrenia can safely stop or reduce their current medication without worsening symptoms. It is designed for people who need ongoing psychiatric care.
Rogers, ArkansasAges 18–65 - NCT06953869RecruitingPhase 3
Testing a sleep medicine for children with insomnia
This study tests if the drug tasimelteon helps children with insomnia sleep better compared to a placebo (a pill with no medicine). It is for children aged 2 to 17 who have been diagnosed with insomnia that is not caused by another medicine.
Dothan, AlabamaAges 2–17 - NCT06866379Recruiting
Brain study on alcohol use disorder: septal nuclei
This study uses brain scans (fMRI) to look at a small area deep in the brain called the septal nuclei, which may play a role in alcohol use disorder. It aims to understand how the brain's structure and activity relate to heavy drinking, which could lead to better treatments.
FrederiksbergAges 30–65 - NCT06956781Recruiting
Finding the best treatment for childhood PTSD
This study tests different ways to help children ages 8-17 who have PTSD after a traumatic event. It looks at how to best support both the child and their caregiver through therapy and surveys.
Rochester, New YorkAges 8–17 - NCT06961058Recruiting
Telehealth vs. in-person follow-up for opioid addiction treatment
This study compares follow-up care after an emergency department visit for opioid addiction: either through telehealth (video visits) or in-person appointments. The goal is to see which method helps people stay in treatment after they leave the ED.
El Centro, CaliforniaAges 18 years+
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,780 recruiting psychiatry studies from the U.S. registry right now, out of 12,430 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.