Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,780 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1251
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease339
- Autism Spectrum Disorder240
- Dementia227
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder142
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Suicidal Ideation89
- Mild Cognitive Impairment (MCI)88
Leading sponsors
- VA Office of Research and Development105
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- The University of Hong Kong51
- Karolinska Institutet50
Where studies are running
- California520
- Massachusetts267
- New York256
- Texas209
- Maryland176
- Pennsylvania171
- Florida149
- Alabama118
- Arizona108
- Illinois104
Recruiting studies7,780 total
- NCT06919432Recruiting
tACS brain stimulation for teens with self-harm
This trial tests if a gentle brain stimulation technique called tACS (transcranial alternating current stimulation) can help reduce non-suicidal self-injury (NSSI) in teens. If you are 12-21 and have had at least 5 self-harm episodes in the past year with one in the last month, you may be eligible.
Shanghai, Shanghai MunicipalityAges 12–21 - NCT02945501Recruiting
Brain stimulation during sleep to improve slow-wave brain timing
This study tests a non-painful brain stimulation during the first part of sleep to see how it affects slow, deep-sleep brain rhythms. It is mainly for healthy young adults who can follow a strict sleep schedule.
Bethesda, MarylandAges 18–39 - NCT05577598Recruiting
Brain scan study of deep brain stimulation in OCD
This trial uses a special PET scan to see how brain sugar use changes during deep brain stimulation for obsessive-compulsive disorder (OCD). It may help researchers understand what brain activity patterns relate to treatment response.
Vienna, State of ViennaAges 18–75 - NCT05815095Recruiting
Early autism screening and follow-up for infants in care
This study helps identify signs of autism and other developmental differences early in babies, and then follows families over time. If you join, you’ll be asked to consent and share information as your child grows up to age 3.
Champigny-sur-MarneAges 3 months–1 year - NCT06588582Recruiting
How cannabis influences perception and feelings
This study looks at how smoking cannabis affects your perception and emotions. It aims to understand why some people use cannabis to cope with stress or negative feelings.
Boulder, ColoradoAges 21–65 - NCT06945055Recruiting
Family support program for early mental health care
This study tests a program to help families support a loved one who is getting coordinated specialty care for early mental health issues. It looks at how involving a family member or support person can make treatment more effective.
Bend, OregonAges 18 years+ - NCT06951919Recruiting
HOBSCOTCH study for memory help in MS
This trial tests a program called HOBSCOTCH to help people with MS who have memory or thinking problems. It also includes a caregiver who supports them.
Lebanon, New HampshireAges 20–75 - NCT06950905Recruiting
Meditation study for women's well-being
This study explores whether a regular meditation practice can improve well-being in women. You might qualify if you are a woman aged 30–60 with some meditation experience and live in Spain.
Zaragoza, ZaragozaAges 30–60 - NCT06943404RecruitingPhase 2
BXCL501 after a car crash to help recovery
This study tests a medication called BXCL501 to see if it helps people recover from stress after a motor vehicle crash. You can join if you went to the emergency room within 3 days of the crash and are expected to go home.
Jacksonville, FloridaAges 18–65 - NCT06942429Recruiting
Comparing stepped vs. tailored care for youth anxiety
This study compares two ways of delivering cognitive behavioral therapy (CBT) to children and teens with anxiety. Participants will receive a treatment plan that is either stepped (starting with simpler options and increasing if needed) or stratified (matched to their specific needs from the start).
LundAges 8–17 - NCT06949813Recruiting
Preventing mood symptoms after C-section
This study tests a program to help prevent depression, anxiety, or trauma symptoms in people who have a cesarean delivery. It is for pregnant people who are in the hospital for at least 3 days before their C-section due to a high-risk pregnancy.
Aurora, ColoradoAges Any age - NCT06947538Recruiting
Stepped care for PTSD: a study at Boston Medical Center
This study tests a step-by-step approach to treat posttraumatic stress disorder (PTSD). It aims to help you feel better by offering different treatment options based on your needs.
Boston, MassachusettsAges 18 years+ - NCT06943859RecruitingPhase 2
Ketamine for opioid use disorder
This study tests whether ketamine, when added to methadone treatment, helps reduce opioid use and cravings. It is for adults with opioid use disorder who are already in a methadone program and have had recent cravings or illicit use. The trial involves multiple visits and follow-up assessments.
Baltimore, MarylandAges 18–65 - NCT06943573RecruitingPhase 2
Psilocybin therapy for bipolar ii depression
This study tests whether a psychedelic drug called psilocybin (the active ingredient in 'magic' mushrooms), combined with therapy, can help relieve depression in people with bipolar II disorder who haven't gotten better with other treatments. You'll receive the drug in a supervised setting and attend follow-up visits to see how it affects your mood.
Vancouver, British ColumbiaAges 19–65 - NCT06949644Recruiting
Pupil light reflex test in delayed sleep phase disorder
This study uses a simple camera test (pupillometry) to measure how your pupils react to light, which may help understand delayed sleep-wake phase disorder. It could be a way to better diagnose or treat this condition.
Chicago, IllinoisAges 16 years+ - NCT06942494Recruiting
CBT Self-Help for Teens with OCD (Family-Based)
This study tests a family-based cognitive behavioral therapy (CBT) self-help program for teens with OCD. It's designed to help you and a parent work together to manage OCD symptoms at home.
Xuhui, Shanghai MunicipalityAges 10–17 - NCT06949943Recruiting
Meditation before cancer surgery to reduce anxiety
This trial tests if listening to a guided meditation recording before surgery can help lower anxiety. If you are scheduled for cancer surgery and are at least 18 years old, you may be able to take part.
Columbus, OhioAges 18 years+ - NCT06944314Enrolling by invitation
Doctors' views on pain during flexible cystoscopy with local anesthetic
This trial asks doctors to rate how much pain they think male patients feel during a minimally invasive bladder exam. It aims to see if doctors' estimates of pain are accurate.
Istanbul, IstanbulAges 18 years+ - NCT06949826RecruitingPhase 4
Buprenorphine for pain after ankle fracture surgery
This trial tests if buprenorphine, a non-opioid pain medicine, works well for people who have not used opioids before. After ankle fracture surgery, you would get buprenorphine instead of stronger opioids to see if it controls pain just as well with fewer side effects.
St Louis, MissouriAges 18 years+ - NCT06950190Enrolling by invitationPhase 3
Exercise and thinking skills during chemotherapy
This study tests whether a structured exercise program can help protect thinking and memory in adults receiving chemotherapy for cancer. If you are able to walk on your own and do light exercise, this trial might be a good fit.
Schenectady, New YorkAges 18 years+ - NCT06944847Recruiting
Vaping and smoking study for people with schizophrenia
This study looks at habits of vaping and smoking in people with schizophrenia. It may help researchers understand how to better support people who want to reduce or quit nicotine use.
Buffalo, New YorkAges 21–50 - NCT06948903Recruiting
Fibromyalgia, brain sensitivity and thinking
This study looks at how the brain's pain sensitivity (central sensitization) relates to memory and thinking problems in people with fibromyalgia. Participating could help doctors understand and treat these symptoms better.
Istanbul, UskudarAges 18–65 - NCT06951542Enrolling by invitation
Reducing HIV and mental health stigma in Malawi
This study tests a program to reduce stigma for people living with HIV who also have symptoms of depression. It aims to improve mental health and HIV outcomes.
MulanjeAges 18 years+ - NCT06942455Recruiting
Better sleep for urban Latino middle schoolers
This study tests a sleep hygiene program to improve sleep health in Latino children aged 11-13 who sleep 9 hours or less per night. It aims to help kids get better rest and feel better overall.
Providence, Rhode IslandAges 11–13
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,780 recruiting psychiatry studies from the U.S. registry right now, out of 12,430 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.