Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,779 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1250
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease338
- Autism Spectrum Disorder239
- Dementia228
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder143
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Mild Cognitive Impairment (MCI)89
- Suicidal Ideation89
Leading sponsors
- VA Office of Research and Development104
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- Karolinska Institutet51
- The University of Hong Kong51
Where studies are running
- California520
- Massachusetts267
- New York255
- Texas209
- Maryland176
- Pennsylvania170
- Florida149
- Alabama118
- Arizona109
- Illinois104
Recruiting studies7,779 total
- NCT06071221Recruiting
Mental health program for home health aides
This study tests a program to help home health aides feel better mentally. If you are a home health aide who speaks English or Spanish, has mild depression, high stress, or loneliness, and has at least 1 year of experience, you may be able to join.
New York, New YorkAges 18 years+ - NCT06059313Recruiting
Personality study for people with memory or behavior changes
This study looks at how personality may have changed before the onset of different types of memory or behavior disorders (like frontotemporal dementia, Alzheimer's, or bipolar disorder). Researchers will talk with a family member or close friend who knew you well before the illness started.
NantesAges 18 years+ - NCT01818661RecruitingPhase 4
Imaging study for progressive apraxia of speech
This trial uses repeated brain scans to study how progressive apraxia of speech changes over time. It may help doctors better understand the condition and improve future tracking and care.
Rochester, MinnesotaAges 18 years+ - NCT06052943Recruiting
Health Without Barriers: Teens and Families
This trial tests a program designed to help teens and families stay healthy. It is available for families living in certain counties in Colorado and aims to support overall well-being.
Durango, ColoradoAges 11–19 - NCT05839067Recruiting
Support program for U.S. veterans living with heart failure
This trial supports U.S. Veterans who have heart failure, to see whether the added support improves health and well-being. You may be able to join if you meet the age, diagnosis, and communication requirements.
Gainesville, FloridaAges 18 years+ - NCT05788302Recruiting
Studying prolonged exposure for PTSD and how it helps
This trial studies how a therapy called “prolonged exposure” works for people with post-traumatic stress disorder (PTSD). You may be able to join if you have PTSD, are interested in starting prolonged exposure, and meet other safety and participation rules.
Boston, MassachusettsAges 18 years+ - NCT04373629Recruiting
Testing how flexible appearance worries may change in BDD
This study looks at whether training can change how people with body appearance worries (including body dysmorphic disorder) perceive faces or the head. It may help researchers understand new ways to reduce distress related to these concerns.
Toronto, OntarioAges 18–40 - NCT03578003Recruiting
Bright morning light to improve sleep in veterans
This study tests whether using bright morning light can improve sleep quality in veterans. You may be able to join if you’re not already using a light box and you don’t have certain eye or mood conditions.
Portand, OregonAges 18 years+ - NCT06043154Recruiting
Study on gut bacteria and anorexia nervosa during refeeding
This study looks at how gut bacteria change in women with anorexia nervosa during refeeding. It aims to find new insights that could improve treatment.
NantesAges 15 years+ - NCT05078970Recruiting
Teen suicide intervention study for high-risk times
This study tests a suicide intervention approach for teens who are having suicidal thoughts or behaviors and are currently in an emergency or hospital setting. It may help you and your care team better support teens during the most risky period.
Columbus, OhioAges 11–17 - NCT06050369Recruiting
Study of repetitive behaviors in OCD and Tourette syndrome
This study looks at repetitive behaviors in people with OCD or Tourette syndrome. It uses MRI scans to understand the brain, and aims to help improve treatments for these conditions.
CréteilAges 15–65 - NCT04922762Recruiting
Exercise program study for blood vessel function in mental health
This study looks at how an exercise program affects blood vessel function (“vascular function”) in people with certain mental health conditions, and compares them to people without those symptoms. It may help researchers understand whether exercise could improve heart and blood vessel health alongside mental health symptoms.
Richmond, VirginiaAges 18–35 - NCT05766254Recruiting
Brain stimulation study for nicotine dependence and reward activity
This trial tests different targets for repetitive transcranial magnetic stimulation (rTMS)—a non-surgical brain stimulation—to change brain “reward” activity in people who are nicotine dependent. If you qualify, you may receive sessions of brain stimulation as the researchers look for the best brain target.
Newark, New JerseyAges 18–55 - NCT06052254RecruitingPhase 2
Skin patch for agitation in Alzheimer's dementia
This trial tests a skin patch that delivers a medicine called dexmedetomidine to help calm agitation in people with Alzheimer's disease. It might be an option for those living in a care facility who have had recent episodes of agitation.
Chino, CaliforniaAges Any age - NCT06044675RecruitingPhase 2
MDMA plus therapy for PTSD – a study with a partner
This study tests whether MDMA, combined with a type of talk therapy called CBCT (cognitive behavioral conjoint therapy), is more effective than CBCT alone for treating PTSD. You and a close partner will both participate in therapy sessions and take MDMA together.
Toronto, OntarioAges 18–80 - NCT05691439Recruiting
Sleep Timing, Mood, and Brain Circuits in Teens With Depression
This study looks at how sleep timing affects brain function related to mood and “pleasure” in teenagers who have depressive symptoms. It may help researchers understand why depression and reduced interest/pleasure can happen, and how sleep patterns might be a key factor.
Eugene, OregonAges 14–18 - NCT06054828Recruiting
Modified ICU program to prevent confusion
This trial tests a special program for people in the ICU who are on a breathing machine. The program aims to prevent confusion and help patients recover better.
Taipei, National Taiwan UniversityAges 18 years+ - NCT06033599RecruitingPhase 3
Mindfulness and motivation to quit smoking while on methadone
This study combines counseling (motivational interviewing) with mindfulness training (like guided exercises) to help people on methadone quit smoking. It tests if adding mindfulness can make it easier to stop smoking and stay quit.
New Brunswick, New JerseyAges 18 years+ - NCT06038721Recruiting
Unified Protocol for kids with emotional concerns
This trial tests a program called Unified Protocol for children ages 7–17 who have emotional difficulties like anxiety, depression, trauma, or obsessive-compulsive symptoms. It aims to help kids and their parents learn skills to manage these feelings together.
Coral Gables, FloridaAges 7–17 - NCT06047691Recruiting
Couples therapy for veterans with PTSD
This study compares two types of couples counseling for military couples where one partner has PTSD. It aims to see if intensive couples therapy improves relationships and PTSD symptoms better than a relationship education program.
San Antonio, TexasAges 18 years+ - NCT06034821Enrolling by invitationPhase 4
ECT vs. ketamine for suicidal depression in adults
This trial compares two treatments—ECT (electroconvulsive therapy, which uses electrical stimulation) and ketamine (a medicine given as a shot)—to see which works better for quickly reducing suicidal depression. It is for adults who are in a severe depressive episode with active suicidal thoughts.
San Francisco, CaliforniaAges 18–90 - NCT06041581Enrolling by invitation
Insomnia treatment study for heart health
This study tests whether treating insomnia can help lower your risk for heart disease. If you have trouble sleeping and certain heart risk factors, you may be able to join.
Indianapolis, IndianaAges 40 years+ - NCT06050304Recruiting
Crack cocaine use and behavioral sensitization study
This study looks at how your body and mind might get more sensitive to crack-cocaine over time (behavioral sensitization) and what you expect from using it. Your participation helps us better understand addiction patterns.
ParisAges 18 years+ - NCT06049953Recruiting
Mothers and babies: a study on antipsychotic use in pregnancy
This study is for pregnant women with serious mental health conditions (like bipolar disorder or a psychotic disorder). It looks at how antipsychotic medications might affect both mothers and their babies, and aims to help guide safer treatment during pregnancy.
New York, New YorkAges 18 years+
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,779 recruiting psychiatry studies from the U.S. registry right now, out of 12,461 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.