Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 8,192 recruiting studies in this area right now.
By phase
- Not applicable6,797
- Phase 2511
- Phase 1258
- Phase 3244
- Phase 4213
- Phase 1/Phase 298
- Phase 2/Phase 371
Top conditions
- Depression420
- Anxiety412
- Alzheimer Disease342
- Autism Spectrum Disorder258
- Dementia226
- Mild Cognitive Impairment199
- Schizophrenia192
- Major Depressive Disorder188
- Cognitive Impairment157
- Insomnia152
- Alcohol Use Disorder150
- Opioid Use Disorder145
- Stress136
- PTSD110
- Autism95
- Mental Health92
- Suicidal Ideation92
- Anxiety Disorders85
Leading sponsors
- VA Office of Research and Development104
- Yale University95
- Massachusetts General Hospital78
- Stanford University72
- Assistance Publique - Hôpitaux de Paris65
- Johns Hopkins University63
- University of California, Los Angeles61
- The University of Hong Kong52
- University of Pennsylvania52
- Karolinska Institutet50
Where studies are running
- California529
- New York267
- Massachusetts263
- Texas223
- Maryland176
- Pennsylvania175
- Florida153
- Alabama118
- Arizona117
- Connecticut113
Recruiting studies8,191 total
- NCT06441786Recruiting
Group therapy for depression and anxiety in autistic teens
This trial tests a group therapy that helps teenagers with autism who also have anxiety or depression learn skills to manage their thoughts and feelings. It takes place at a clinic in Stockholm.
Haninge, Stockholm CountyAges 15–18 - NCT07102914Enrolling by invitation
Education program health survey study
This study looks at how a short program at adult education centers might help students and staff. It aims to understand what kind of support could be most useful for people working on their high school diploma or GED.
New Haven, ConnecticutAges 17 years+ - NCT06246955Recruiting
Online group therapy to improve wellbeing in cancer patients
This study tests two types of online group therapy—Acceptance and Commitment Therapy and Compassion-Based Therapy—to help people with cancer feel better emotionally. You'll join a small group with a therapist to learn skills for handling stress and finding peace.
Scottsdale, ArizonaAges 18 years+ - NCT07496255Recruiting
Virtual reality for memory help after ICU confusion
This trial tests whether using virtual reality (VR) can help older adults recover their thinking and memory after a serious illness and confusion in the ICU. You may be eligible if you are 50 or older, spent time on a breathing machine, and had delirium in the ICU.
Indianapolis, IndianaAges 50 years+ - NCT05731856Recruiting
Using a phone tool to improve stress control in doctors
This study tests whether changing your heart-rate patterns using a phone tool can help doctors better manage stress. You may be asked to use study methods for a period of time to see if stress improves.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06098521Recruiting
CBT to prevent sexual reoffending for men in prison
This study tests if cognitive behavioral therapy (a talking therapy that changes thinking patterns) can help men in prison avoid committing another sexual offense after release. If you are a man serving time for a sexual crime and have an average or higher risk of reoffending, this therapy might be an option for you.
Stockholm, Stockholm CountyAges 18 years+ - NCT06288282Recruiting
Predicting pain and opioid misuse in chronic back pain
This study looks at how thinking and behavior affect long-term pain and opioid use in people with chronic lower back pain. It aims to find better ways to manage pain and prevent medication misuse.
New York, New YorkAges 18 years+ - NCT06254924Recruiting
Qoyangnuptu app for southwestern tribal youth
This study tests a smartphone app called Qoyangnuptu for young people from Southwestern Tribal communities. The app is designed to support your wellbeing, and taking part could help you build healthy habits.
Flagstaff, ArizonaAges 14–25 - NCT06854328Recruiting
Prism PTSD study for adolescents
This trial tests a new non-invasive device that uses brain imaging to help treat PTSD symptoms in teens and young adults. It may be a good option if you haven't yet completed a full course of trauma-focused therapy.
New York, New YorkAges 12–21 - NCT02726061Recruiting
Online psychological support for depression
This study tests an internet-based (online) psychological support program for adults who are feeling depressed. It may help participants by offering structured support without needing in-person visits.
Lebanon, New HampshireAges 18 years+ - NCT07084454Enrolling by invitationPhase 3
Remote geriatric care for older adults starting cancer treatment
This trial tests whether remote health assessments and support can improve care for adults 65+ who are starting a new cancer treatment. You'd participate from home via telehealth visits.
Rio de Janeiro, Rio de JaneiroAges 65 years+ - NCT03764098RecruitingPhase 2
Guanfacine to reduce heavy drinking in adults with alcohol use disorder
This Phase 2 study tests whether guanfacine can reduce drinking in women and men who drink heavily and meet criteria for alcohol use disorder. It also looks at how the medicine affects drinking patterns in a controlled setting.
New Haven, ConnecticutAges 21–70 - NCT06263660RecruitingPhase 2
Keto supplement for depression with inflammation
This study tests a keto-like supplement to see if it helps change how the brain responds to emotional situations in people with depression and higher inflammation. It involves MRI brain scans and blood tests.
Tulsa, OklahomaAges 18–65 - NCT06248762Recruiting
App for parents: PPI and mindfulness for kids with NDD
This trial tests a digital app that combines PPI (positive psychology exercises) and mindfulness for parents of children with or suspected of a neurodevelopmental disorder (NDD). It aims to help you manage stress and feel better through daily use for about 15 minutes.
EnschedeAges 18 years+ - NCT06273995Recruiting
Behavioral activation through telehealth for teens with depression
This trial tests if a telehealth program can help teenagers with depression feel better by increasing positive activities. You and a caregiver will attend weekly video sessions for 8 weeks.
Houston, TexasAges 12–18 - NCT06752759RecruitingPhase 3
Ketamine mist for depression
This trial tests if a ketamine mist you breathe in can help treat moderate to severe depression. It is for adults who are not helped enough by other treatments.
Brooklyn, New YorkAges 18–88 - NCT06878885Recruiting
Heart health & trauma study for American Indian adults
This study looks at how trauma affects heart and metabolic health in American Indian adults living on or near the Blackfeet reservation.
Browning, MontanaAges 18–40 - NCT07284368Enrolling by invitation
Advance Choice Document study for mental health care
This study looks at how Advance Choice Documents (ACDs) can help people who have been detained under the Mental Health Act. It aims to understand how these documents are made and used, so that future care can better respect your wishes.
LondonAges 16 years+ - NCT03438526RecruitingPhase 4
Melatonin treatment for low-activity delirium in ICU patients
This trial tests whether giving melatonin (or a placebo) can help adults in the intensive care unit who have a specific type of confusion called low-activity delirium. It aims to improve recovery by supporting sleep–wake regulation in the ICU.
BaselAges 55 years+ - NCT05383495RecruitingPhase 3
Calming medicine during child laceration repair
This trial tests a calming/anxiety-reducing medicine to see if it helps children feel less scared during stitches for a skin cut. It may help make the repair process easier for children and their caregivers.
London, OntarioAges 2–12 - NCT06289010Recruiting
Family therapy for childhood depression: brain study
This study tests whether a family-focused therapy can help children ages 7 to 12 with depression. It looks at how the brain changes during treatment using an MRI scan.
Boston, MassachusettsAges 7–12 - NCT06790576RecruitingPhase 1
Optimizing TMS for stimulant use disorder
This test uses a safe, non-invasive brain stimulation method called TMS (transcranial magnetic stimulation) to see if it can help people with stimulant use disorder reduce their cravings and stay sober. You would need to be in an addiction treatment program and have been clean for at least 2 weeks to join.
Minneapolis, MinnesotaAges 18 years+ - NCT06789926Recruiting
Support program for oncology nurses
This trial tests a multimedia support platform and a therapy workshop (ACT) to help oncology nurses manage stress and improve their well-being. If you're an oncology nurse, you can join and learn new coping skills.
TaipeiAges 20 years+ - NCT07281729Enrolling by invitation
Suicide risk factors study for mood disorders
This study looks at why some people with mood disorders (like depression or bipolar disorder) think about or attempt suicide. By finding the risk factors, doctors hope to better prevent suicide. The study involves filling out questionnaires.
Shanghai, Shanghai MunicipalityAges 16–60
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 8,192 recruiting psychiatry studies from the U.S. registry right now, out of 13,292 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Blood & lymphatic
- Kidney & urinary
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- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.