Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,764 recruiting studies in this area right now.
By phase
- Not applicable6,413
- Phase 2492
- Phase 1247
- Phase 3239
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 367
Top conditions
- Anxiety388
- Depression381
- Alzheimer Disease338
- Autism Spectrum Disorder240
- Dementia226
- Mild Cognitive Impairment195
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder142
- Opioid Use Disorder140
- Stress117
- PTSD105
- Mental Health98
- Autism94
- Mild Cognitive Impairment (MCI)88
- Suicidal Ideation87
Leading sponsors
- VA Office of Research and Development105
- Yale University86
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University61
- University of California, Los Angeles58
- The University of Hong Kong51
- University of Pennsylvania51
- Karolinska Institutet50
Where studies are running
- California517
- Massachusetts266
- New York254
- Texas209
- Maryland175
- Pennsylvania169
- Florida147
- Alabama118
- Arizona109
- Illinois103
Recruiting studies7,764 total
- NCT07563777Recruiting
Long-term study of human aging and health
This is a long-term research study that follows people over time to understand how humans age. Researchers will collect information about your health and lifestyle to learn what helps people stay healthier as they get older.
Boulder, ColoradoAges 18 years+ - NCT07565428RecruitingPhase 3
Study of roluperidone for negative symptoms of schizophrenia
This trial tests a new medicine called roluperidone for people with schizophrenia who have ongoing negative symptoms (like low motivation or social withdrawal) but stable positive symptoms (like hallucinations). It aims to see if the drug helps with these symptoms and if it can reduce the chance of relapse compared to other medications.
Bellflower, CaliforniaAges 18–55 - NCT06732128Recruiting
Nature virtual reality for depression in Alzheimer's disease
This trial tests whether a virtual reality nature experience can help improve mood in people with early-to-moderate Alzheimer's disease. Participants will use a VR headset and a few apps at home, with a caregiver present, over several sessions.
Toronto, OntarioAges 50 years+ - NCT06733883Recruiting
Music therapy for teens with emotional difficulties
This trial tests if music therapy can help adolescents aged 13 to 18 who are struggling with emotional challenges. If you join, you may attend music therapy sessions that could improve how you feel.
Oslo, NydalenAges 13–18 - NCT06733714Recruiting
Brain stimulation plus memory training for older adults
This study tests whether a gentle, non-invasive electrical current applied to the scalp (tACS) combined with computer-based brain exercises can improve memory and thinking in older adults who have concerns about their cognitive health.
Rio de Janeiro, Rio de JaneiroAges 50 years+ - NCT06732219Recruiting
Pilot trial to prevent relapse of severe problem behavior
This trial tests a new way to help children and teens with intellectual or developmental disabilities (IDD) avoid relapsing into severe problem behaviors like aggression or self-injury. It focuses on behaviors that are triggered by wanting attention or access to favorite items.
Auburn, AlabamaAges 6–17 - NCT06732089Recruiting
Digital help for stubborn depression
This trial tests a digital program (smartphone app or website) to help people with tough-to-treat depression. If you are already receiving advanced treatments like rTMS, ketamine, or ECT at St. Michael's Hospital, you may be able to join and see if this extra digital support improves your mood.
Toronto, OntarioAges 18 years+ - NCT04038840RecruitingPhase 1
Brain PET-MR imaging to study schizophrenia connections
This early (Phase 1) study uses a special brain scan to look at synapses—the contact points between brain cells—in people with schizophrenia-related conditions. It helps researchers understand brain activity and connection patterns, which may guide future tests or treatments.
Palo Alto, CaliforniaAges 18–65 - NCT04276922Recruiting
Creative arts program to reduce healthcare burnout
This study tests a creative arts program to help reduce burnout symptoms in people who work in hospitals. If you’re feeling emotionally drained or disconnected at work, participating may help you build coping and well-being skills.
Aurora, ColoradoAges 18–85 - NCT05614661Recruiting
Postpartum support for mothers using opioid treatment
This study tests a postpartum intervention for mothers diagnosed with opioid use disorder (or receiving opioid addiction treatment) to help during the period after having a baby. You may be eligible if you have a young child and can complete the study tasks, including possible questionnaires and an MRI if needed.
Ann Arbor, MichiganAges 18–50 - NCT06415838Recruiting
Behavioral activation for depression in older adults
This trial tests a simple, practical therapy called behavioral activation to help older adults with depression feel better. It's done in your local community, not in a hospital.
Eskilstuna, SörmlandAges 65 years+ - NCT07564635Recruiting
Roots for Life: Mental Health Support in Schools
This study tests a program designed to strengthen mental health and well-being in school communities across Chile and Ecuador. Researchers will work with children, teachers, and parents to understand how the program helps kids feel better emotionally and socially.
Achao, ChiloeAges 5 years+ - NCT07563296RecruitingPhase 2
Ketamine therapy to reduce stress after severe burns
This study tests whether ketamine-assisted therapy (a medication combined with counseling) can help people recover emotionally after suffering severe burn injuries. The goal is to reduce stress, anxiety, and trauma symptoms during healing.
Salt Lake City, UtahAges 18–65 - NCT07566910Enrolling by invitation
Vagus Nerve Stimulation to Reduce Pain During Burn Dressing Changes
This study tests a non-invasive device that stimulates a nerve in your ear to help reduce pain and stress during burn wound dressing changes. The device is applied to the outer ear and may help your body manage pain naturally without extra medication.
Istanbul, KartalAges 18–65 - NCT07561632Recruiting
Early Stress Screening After Emergency Cesarean Delivery
This study looks at whether certain signs of distress right after an unexpected cesarean delivery can predict who might develop PTSD (post-traumatic stress disorder) later. Researchers want to understand this connection so they can help women who are struggling after this traumatic birth experience.
Vancouver, British ColumbiaAges 19 years+ - NCT07566923Enrolling by invitation
Vagus Nerve Stimulation for Teen Burn Recovery
This study tests a non-invasive device placed on the ear that stimulates the vagus nerve (a major nerve that affects stress and healing) to help adolescents recovering from burns feel less anxious, sleep better, and experience less pain and itching. The device is worn on the outside of the ear and may help your body heal.
Istanbul, KartalAges 12–18 - NCT07567664Enrolling by invitation
Brain Changes in Neurodegenerative Diseases: A Tracking Study
This research study tracks how brain damage progresses in rare neurodegenerative diseases like frontotemporal dementia, primary progressive aphasia, PSP, CBS, and ALS. Researchers use brain imaging and tests to understand how these diseases spread in the brain, which could help develop better treatments.
Milan, LombardyAges 20–85 - NCT07565714Recruiting
AI-Guided Imagery Therapy for Anxiety and Childhood Memories
This research tests a new computer-assisted therapy that helps people with anxiety process difficult childhood memories involving parental criticism. The AI guides you through imagining and reworking these memories to reduce anxiety symptoms.
Poznan, WielkopolskaAges 18–35 - NCT07566871Enrolling by invitation
Nerve Stimulation to Help Burn Injury Recovery
This study tests whether gentle electrical stimulation of a nerve in your ear can help reduce anxiety, improve sleep, and ease pain or itching after a burn injury heals. You would wear a small device on your ear for several weeks.
Istanbul, KartalAges 18–65 - NCT07562048Recruiting
Comfort Cuddling for Children in Critical Care
This study looks at whether gentle cuddling and physical comfort help children feel better while they're in the intensive care unit. Researchers believe close contact with caregivers may reduce stress and improve how children recover.
Calgary, AlbertaAges Up to 18 years - NCT07563517Recruiting
Peer coaching for substance use support in jail
This study tests whether connecting people in jail with peer coaches—people with lived experience of substance abuse recovery—can help them stay engaged with care after release. You'd receive support calls and guidance from someone who understands recovery firsthand.
Atlanta, GeorgiaAges 18 years+ - NCT07563868Recruiting
Coaching to help ketamine therapy for hard-to-treat depression
This study tests whether adding coaching sessions can help people who are already getting ketamine or esketamine treatment for depression that hasn't responded to other medications. You'd receive weekly coaching calls designed to support your recovery while you continue your regular ketamine clinic visits.
Boston, MassachusettsAges 18 years+ - NCT07564778Recruiting
Pain Management After Cardiac Arrest Recovery
This study examines how to better treat pain in patients who have survived cardiac arrest and are unconscious in the hospital. Researchers want to understand pain experiences and test pain-relief strategies during early recovery.
HalmstadAges 18 years+ - NCT07563244Recruiting
Computer Brain Training for Confusion in Older Adults
This study tests whether using a computer program to do brain exercises can help older adults recover from delirium—a state of confusion that sometimes happens after hospitalization. The goal is to see if this mental stimulation helps people think more clearly and recover faster.
Reus, TarragonaAges 60 years+
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,764 recruiting psychiatry studies from the U.S. registry right now, out of 12,350 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Pain
- Injuries & trauma
- Mouth & dental
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.