Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,771 recruiting studies in this area right now.
By phase
- Not applicable6,418
- Phase 2494
- Phase 1248
- Phase 3237
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 368
Top conditions
- Anxiety387
- Depression381
- Alzheimer Disease337
- Autism Spectrum Disorder241
- Dementia224
- Mild Cognitive Impairment194
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder142
- Opioid Use Disorder141
- Stress117
- PTSD105
- Mental Health99
- Autism95
- Mild Cognitive Impairment (MCI)88
- Suicidal Ideation87
Leading sponsors
- VA Office of Research and Development105
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University61
- University of California, Los Angeles58
- The University of Hong Kong52
- University of Pennsylvania52
- Karolinska Institutet50
Where studies are running
- California516
- Massachusetts264
- New York255
- Texas209
- Maryland174
- Pennsylvania169
- Florida145
- Alabama118
- Arizona109
- Illinois104
Recruiting studies7,771 total
- NCT05698576Recruiting
Laser treatment through the skin for men with prostate cancer
This trial tests a laser procedure done through the skin between the scrotum and anus, guided by MRI and ultrasound, for men with certain prostate cancer types. It aims to heat and treat prostate cancer while checking safety and outcomes over follow-up visits.
Hialeah, FloridaAges 50–80 - NCT05703789Recruiting
Dental treatment for severe long-term eating disorders
This study focuses on people with severe eating disorders lasting many years and looks at dental needs, since these can lead to extensive tooth damage. You may be eligible if you need significant dental treatment on at least one jaw.
StockholmAges 18–50 - NCT04512755Recruiting
AIMS medical outcomes study for new or established patients
This is an observational study where the AIMS team collects information from patients during a first visit or ongoing care. It helps the clinic understand patients’ experiences and outcomes, but it does not test a new medicine.
Seattle, WashingtonAges Any age - NCT03542734Recruiting
Imaging study for thinking and brain changes in older adults
This study looks at brain scans and eye/eye-nerve findings to understand why thinking can change with aging. It may help researchers connect eye and brain changes, which could guide future ways to prevent or detect dementia early.
HangzhouAges 40 years+ - NCT04436081RecruitingPhase 2
CBD oil without THC for agitation in Alzheimer’s dementia
This trial studies whether a THC-free CBD oil softgel can reduce agitation in people with Alzheimer’s-related dementia. It compares CBD to a control to see if it improves difficult behaviors and is safe over the study period.
Norfolk, VirginiaAges 50–90 - NCT05746715Recruiting
Study of people at risk for inherited CJD before symptoms
This study follows people who have a close family member with inherited Creutzfeldt-Jakob disease (CJD) to understand how the disease develops before any symptoms. It may involve genetic testing and safety-required procedures like brain scans and a spinal fluid test to learn about early changes.
Tel AvivAges 50 years+ - NCT05649605Recruiting
Testing early response to gender-affirming hormone treatment
This study looks at how people respond early after starting gender-confirming hormones. It may help doctors understand what changes happen soon after treatment starts and how to manage it safely.
StockholmAges 18–99 - NCT04107870Recruiting
Virtual reality therapy for body-image distress in teen anorexia
This study tests whether virtual reality exposure therapy can improve body-image distress in female teens with anorexia nervosa. It may help reduce distress related to seeing or thinking about their body.
ReimsAges 13–17 - NCT03589183Recruiting
Gut microbiome study for ulcerative colitis and Crohn disease
This study looks at how changes in gut bacteria (the microbiome) relate to inflammatory bowel disease, including ulcerative colitis and Crohn disease. It may help researchers understand what might improve symptoms or disease control.
SeoulAges Any age - NCT05366270Recruiting
Testing how mild heat affects depression symptoms and brain signals
This study tests whether controlled whole-body heat can change immune-related brain and body signals in people with major depressive disorder. It may help researchers understand why heat affects mood and who might benefit, while closely monitoring safety.
Boston, MassachusettsAges 18–65 - NCT05767203Recruiting
Study genetic and blood markers in people with inherited intellectual disability
This study looks at genetic-related and blood/biologic markers in people with an inherited (genetic) intellectual disability. The goal is to better understand these differences and how they might relate to the condition.
ParisAges Any age - NCT05408247RecruitingPhase 4
N-acetylcysteine to help people cut back on alcohol
This trial tests whether N-acetylcysteine (a supplement-like medicine) can help people with alcohol use disorder reduce or stop drinking. You may be randomly assigned to receive N-acetylcysteine or a comparison treatment, and you’ll complete interviews during the study.
Sydney, New South WalesAges 18–70 - NCT05773443Recruiting
Digital program plus an oral drug for Lewy body dementia
This study tests an eHealth program together with a patient-and-caregiver support program, along with a medicine called ambroxol. It aims to see whether this combined approach is safe and helpful for people with dementia with Lewy bodies (or early memory changes from it).
Haugesund, RogalandAges 50–85 - NCT05786898Recruiting
Test a computer training program to improve autism-related thinking
This study tests a computerized “cognitive remediation” program adapted for people with autism, using social scenarios and skills. The goal is to improve thinking and related day-to-day abilities by practicing structured tasks on a screen.
ParisAges 13–40 - NCT04523909Recruiting
Testing spinal fluid inflammation changes after aortic surgery
This study tracks inflammation-related lab markers in spinal fluid taken through a temporary drain during and after thoracic aortic surgery. It may help doctors understand what inflammatory changes happen around surgery and how they relate to recovery.
NijmegenAges 18 years+ - NCT05800522Recruiting
Supportive parenting program for kids with behavior and mood struggles
This trial tests whether a supportive parenting program can help children who are showing higher-than-usual symptoms like anxiety, depression, anger, or behavior problems. If you’re not already in certain specialized mental health programs, your child may be able to join and get structured support for coping.
OsloAges 4–12 - NCT05798143Recruiting
Testing brain-signal biomarkers in treatment-resistant depression
This trial studies signs in the brain (biomarkers) during an accelerated form of nerve stimulation to treat depression that hasn’t improved with usual antidepressants. It may help researchers learn who benefits and how to better personalize treatment.
ChietiAges 18–65 - NCT05808478Recruiting
Eye-tracking tool for kids who cannot speak well
This trial tests an eye-tracking technology that lets children communicate by using where they look on a screen. It may help children with severe communication needs do tasks and use simple functions without needing speech or hand control.
MessinaAges 3–17 - NCT05648539Recruiting
Music therapy for mood and anxiety symptoms
This trial studies whether music therapy can improve symptoms of depression or anxiety. You may be invited if you have mild mood or anxiety symptoms on common screening questionnaires.
Nanjing, JiangsuAges 16–35 - NCT04844060Recruiting
Study collecting spinal fluid from patients needing a lumbar puncture
This study collects cerebrospinal fluid (the fluid around the brain and spinal cord) during a lumbar puncture. It aims to improve how doctors use this information for accurate diagnosis in patients who need the procedure.
StrasbourgAges Any age - NCT05840575Recruiting
Study of thinking changes in young people during cancer treatment
This study looks at how thinking and memory may change in children and young adults after a new cancer diagnosis, especially around chemotherapy. It may help doctors better understand and track brain-related side effects early.
CopenhagenAges 7–29 - NCT04927533Recruiting
Ronnie Gardiner Method for hospital patients 60+
This study looks at whether the Ronnie Gardiner Method helps people age 60 and older who are in the hospital for mental health and thinking concerns. It will test how effective the method is for improving comfort, daily functioning, or wellbeing.
Tienen, Vlaams-BrabantAges 60 years+ - NCT05778708Recruiting
Tai Chi and aerobic exercise for mood and sleep in late lung cancer
This study tests whether Tai Chi and aerobic exercise can improve clusters of emotional symptoms—like anxiety, low mood, poor sleep, and fatigue—in people with late-stage non-small cell lung cancer. If you have these symptoms and are not already doing regular exercise programs, the trial may offer a structured way to feel better.
Hong KongAges 18 years+ - NCT01635569Recruiting
Testing outcomes for children with moderate to severe OCD
This study looks at how well a treatment approach works for children and teens (ages 5–18) who have obsessive-compulsive disorder (OCD) that is moderate to severe. It may help researchers find better ways to improve symptoms and daily functioning.
Vancouver, British ColumbiaAges 5–18
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,771 recruiting psychiatry studies from the U.S. registry right now, out of 12,287 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.