Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 2,058 recruiting studies in this area right now.
By phase
- Not applicable1,634
- Phase 2148
- Phase 183
- Phase 382
- Phase 459
- Phase 1/Phase 236
- Phase 2/Phase 316
Top conditions
- Periodontitis108
- Nasopharyngeal Carcinoma80
- Periodontal Diseases57
- Dental Caries49
- Gingivitis35
- Oral Cancer35
- Head and Neck Cancer34
- Dental Implant30
- Sjogren's Syndrome29
- Gingival Recession27
- Periodontal Disease27
- Nasopharyngeal Carcinoma (NPC)24
- Alveolar Bone Loss23
- Peri-Implantitis23
- Tooth Loss22
- Oropharynx Cancer21
- Temporomandibular Disorders (TMD)21
- Trigeminal Neuralgia21
Leading sponsors
- Cairo University91
- Sun Yat-sen University53
- Ain Shams University30
- Mansoura University30
- Postgraduate Institute of Dental Sciences Rohtak24
- Al-Azhar University23
- Tanta University23
- University of Baghdad19
- Universidad Complutense de Madrid18
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California40
- Texas27
- Massachusetts22
- Ohio22
- Pennsylvania22
- New York20
- Maryland19
- Florida18
- Alabama16
- Michigan15
Recruiting studies2,058 total
- NCT07507864Recruiting
Testing a Turkish Oral Health Assessment Tool
This study tests a Turkish-language tool that helps nurses check the mouth health of older adults. It aims to see if the tool works well for people aged 60 and older who can understand Turkish.
Konya, KonyaAges 60 years+ - NCT07513727Recruiting
Vitamin C Treatment for Dark Gum Pigmentation
This study tests whether vitamin C can safely lighten dark spots or patches on your gums that are caused by natural pigmentation. If you're bothered by how these dark areas look, this trial may help improve your smile's appearance.
Cairo, Cario GovernorateAges 20–40 - NCT07465952Recruiting
Do price cuts help people get preventive dental care?
This trial tests whether offering different price discounts on dental check-ups encourages people who haven't been to the dentist recently to schedule a preventive visit. You may be eligible if you have a medical appointment soon and have not seen a dentist in the last 6 months.
SantiagoAges 18–70 - NCT07483788Recruiting
Comparing two materials for infected tooth nerve treatment
This study compares two materials (MTA and Biodentine) used to treat a painful, infected nerve in a back tooth. Instead of a full root canal, the dentist will remove only the top part of the nerve and seal it. The goal is to see which material works better to save your tooth.
Karachi, SindhAges 18–40 - NCT07520890Recruiting
Bleeding Risk During Oral Biopsies in Patients on Blood Thinners
This study looks at whether patients taking certain blood-thinning medications (DOACs) have more bleeding during oral biopsies—small tissue samples taken from the mouth. Understanding this helps doctors know how to safely care for patients on these medications.
Pisa, PiAges 18 years+ - NCT07457749RecruitingEarly Phase 1
Comparing two tooth-colored fillings for back teeth cavities
This study tests a new self-hardening filling material against a light-activated bioactive filling for cavities between back teeth. The goal is to see which material works better and lasts longer.
Cairo, El Sherouk CityAges 18–47 - NCT07505485Recruiting
AI for diagnosing jawbone lesions
This trial uses artificial intelligence to better analyze bone lesions or cysts in the jaw. It aims to see if a computer can help dentists make more accurate diagnoses and treatment plans.
BariAges 18–80 - NCT07492576Recruiting
Magnesium shield vs. standard graft for implants
This trial compares two methods for placing dental implants right after removing a failing tooth in the upper front area. It tests whether a magnesium shield helps preserve the bone and gum better than the usual grafting technique.
CairoAges 18–60 - NCT07514585Enrolling by invitation
Testing new dental implant impression tools
This study tests a new type of dental tool (called a bionic healing abutment) used when taking impressions for dental implants. Researchers want to see if this tool makes the implant process easier and more accurate for patients with missing teeth.
Fuzhou, FujianAges 18–65 - NCT07374341Recruiting
Botox for jaw fractures near the joint
This trial is testing whether guided Botox (botulinum toxin) injections into the chewing muscles can help treat certain types of jaw fractures near the joint. It may be an option if you have a mild to moderate break on one side and your bite is stable.
AlexandriaAges 18–40 - NCT07413393Recruiting
Oral health education for new mothers
This trial teaches new mothers about oral health habits after childbirth. It aims to help women care for their teeth and gums, which may improve overall health for both mother and baby.
Valencia, ValenciaAges 18–45 - NCT07440303Recruiting
Comparing two gum graft techniques for lower jaw
This trial tests whether a new type of gum graft (Star Matrix) works as well as the standard gum graft (autogenous graft) for increasing gum width on both sides of the lower jaw. It may help patients who need gum augmentation and want a potentially less invasive option.
Boston, MassachusettsAges 20–80 - NCT07377890Recruiting
Digital vs traditional denture impressions: which is more accurate?
This study compares digital scan impressions to traditional putty impressions for making complete dentures. It aims to find out which method is more accurate for people who have no teeth left and need a full set of dentures.
DubaiAges 18–85 - NCT07315620Recruiting
Dental implant bridge fit using digital methods
This study tests if a fully digital workflow can make dental implant-supported bridges fit better and more comfortably. It may help people who need a full set of implant teeth on the upper or lower jaw.
Madrid, MadridAges 18 years+ - NCT07348094Recruiting
Guided sinus lift with natural blood proteins for dental implants
This trial tests a new method to lift the sinus floor using your own blood proteins, creating more bone for dental implants. It may help people who need implants in the upper back jaw but don't have enough bone height.
Kafr ash Shaykh, KafrelsheikhAges 18–40 - NCT07326345Recruiting
Study comparing ways to widen the upper jaw
This trial tests different methods to widen a narrow upper jaw and see how they affect the nose and face bones. It is for people 15 and older who have a crossbite (when upper teeth sit inside lower teeth).
Istanbul, FatihAges 15 years+ - NCT07343050Recruiting
Testing flowable composites for tooth fillings and sensitivity
This trial is testing if a special type of dental filling material (flowable composite) causes less tooth sensitivity after getting a cavity filled. It may help people with cavities in the back teeth.
Merkez, Rize ProvinceAges 18 years+ - NCT07280455Recruiting
Comparing gold vs. steel retainers after braces
This study compares two types of fixed retainers (gold vs. stainless steel) to see which works better after braces are removed. It's for people aged 15–30 who have completed orthodontic treatment and have a well-aligned lower front teeth.
Baghdad, Baghdad GovernorateAges 15–30 - NCT07344038Recruiting
Bioceramic Putty vs MTA and Crowns for Baby Teeth
This study compares two types of putty used to treat the nerve of a deep cavity in a baby tooth, and then looks at two types of crowns (caps) placed on top. It's for healthy children ages 5–7 who need this treatment on a back baby tooth.
AlexandriaAges 5–7 - NCT07291336RecruitingPhase 4
Comparing two ways to place dental implants
This trial compares two methods for placing dental implants in the upper jaw: dynamic navigation (real-time guidance) versus static navigation (using a surgical guide). It aims to see which technique is more accurate for people missing one tooth between the right and left second premolars.
CairoAges 22–60 - NCT07351812Recruiting
Two treatments for jaw muscle pain
This study compares two different treatments for people who have pain in their jaw muscles (not the joint itself). It aims to find which treatment works better for muscle-related temporomandibular disorders (TMD).
AlexandriaAges 18–45 - NCT07330570Recruiting
Caries risk after dental surgery under general anesthesia
This study looks at how likely children are to get new cavities after they have had dental treatment under general anesthesia for early childhood cavities. It aims to help dentists better understand and prevent future decay.
Aydin, AydınAges 6–16 - NCT07254494Recruiting
Bone Regrowth Guide for Lower Jaw Implants
This study tests two types of membranes used to grow bone in the lower jaw before placing dental implants. Participation lasts about one year and involves a bone-regrowth procedure to prepare for implants.
BeirutAges 18–80 - NCT07220850Recruiting
Oral health help for caregivers of kids having dental surgery
This trial tests a program to help caregivers improve their child's oral health after dental surgery. It may be a good fit if you care for a child under 8 years old who is getting dental surgery at the University of Illinois at Chicago clinic.
Chicago, IllinoisAges Up to 7 years
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 2,058 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,961 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.