Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 2,058 recruiting studies in this area right now.
By phase
- Not applicable1,634
- Phase 2148
- Phase 183
- Phase 382
- Phase 459
- Phase 1/Phase 236
- Phase 2/Phase 316
Top conditions
- Periodontitis108
- Nasopharyngeal Carcinoma80
- Periodontal Diseases57
- Dental Caries49
- Gingivitis35
- Oral Cancer35
- Head and Neck Cancer34
- Dental Implant30
- Sjogren's Syndrome29
- Gingival Recession27
- Periodontal Disease27
- Nasopharyngeal Carcinoma (NPC)24
- Alveolar Bone Loss23
- Peri-Implantitis23
- Tooth Loss22
- Oropharynx Cancer21
- Temporomandibular Disorders (TMD)21
- Trigeminal Neuralgia21
Leading sponsors
- Cairo University91
- Sun Yat-sen University53
- Ain Shams University30
- Mansoura University30
- Postgraduate Institute of Dental Sciences Rohtak24
- Al-Azhar University23
- Tanta University23
- University of Baghdad19
- Universidad Complutense de Madrid18
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California40
- Texas27
- Massachusetts22
- Ohio22
- Pennsylvania22
- New York20
- Maryland19
- Florida18
- Alabama16
- Michigan15
Recruiting studies2,058 total
- NCT07185191Recruiting
Device to treat gum shrinkage and black triangles between teeth
This trial tests a medical device (RDM36) to see if it safely and effectively treats gum shrinkage and black triangles between the front teeth, which can affect your smile.
Brescia, ItalyAges 18 years+ - NCT07249242Recruiting
Gum healing around different healing caps on implants
This study compares how well gum tissue heals around different types of healing caps placed on dental implants. It may help you if you have a recently placed implant that meets certain space and strength requirements.
Boston, MassachusettsAges 18 years+ - NCT07104656Recruiting
Study of a new saw for jaw surgery
This trial tests a new way to cut the jawbone during surgery to see if it helps the bone pieces fit together better. It might help patients needing jaw surgery.
Birmingham, AlabamaAges 12–75 - NCT07722390Recruiting
Injection treatment for deep gum pockets
This study tests whether injecting a special substance made from your own blood can help treat deep gum pockets without surgery. It may be an option for people with advanced gum disease who have already had initial cleaning.
CairoAges Any age - NCT06640205Recruiting
New treatment for painful tooth pulp in molars
This trial tests two different materials to treat the inflamed pulp in your back teeth. It compares a special type of blood concentrate (I-PRF) with a mix of nano MTA and blood concentrate to see which is better at saving the tooth and relieving pain.
CairoAges 15–30 - NCT07339774RecruitingPhase 2
Traditional Chinese medicine for mouth sores from radiation
This trial tests whether a traditional Chinese medicine can help prevent or reduce the severity of mouth sores caused by radiation therapy for head and neck cancer. If you are scheduled to get radiation for non-spreading head or neck cancer, this treatment might help protect your mouth.
Chengdu, SichuanAges 18–65 - NCT07683351Recruiting
Gel for healing after gum graft surgery
This study compares two gels, active oxygen gel and hyaluronic acid gel, to see which one helps the roof of the mouth heal better after a gum graft. It may help reduce discomfort and speed up recovery.
Ismailia, Ismailia GovernorateAges 18–60 - NCT07327060Recruiting
Camera-Assisted Parent Training for Children's Teeth
This study tests whether teaching parents with a small intraoral camera can help improve their child's toothbrushing habits. It focuses on children ages 5–7 who have a new permanent molar coming in.
AydinAges 5–7 - NCT07395401Recruiting
Comparing fillings for baby molar root canals
This study compares two types of filling materials used in root canals of baby molars. It looks at which material works better when the tooth is prepared with either a manual file or a rotating dental tool. This could help children keep their baby teeth longer without pain or infection.
Giza, Giza GovernorateAges 5–8 - NCT07184359Enrolling by invitation
Using social media to help dental students learn
This study tests whether using social media can help dental students learn better in their Dental Radiology course. If you are a student at UFJF's Juiz de Fora campus and use social media, you may be able to join.
Juiz de Fora, Minas GeraisAges 18 years+ - NCT07045779Recruiting
Tongue and mouth muscle patterns in children with open bite
This study looks at children with an anterior open bite to understand their tongue and mouth muscle patterns. It may help find better ways to treat this condition.
GhentAges 6–12 - NCT07678749Enrolling by invitation
Closed sinus lift with bone graft and a natural supplement scaffold
This trial tests whether adding a natural supplement (apigenin) to a bone graft scaffold helps improve bone healing during a closed sinus lift procedure. It may be an option for people who need extra bone in their upper jaw before getting dental implants.
CairoAges 18–50 - NCT07150858Recruiting
New bone graft material for sinus lift with implant
This trial tests a new combination of materials (erythropoietin, albumin, and platelet-rich fibrin) to help rebuild bone in the upper jaw during a sinus lift procedure. If you need a dental implant but have limited bone height, this approach may allow the implant to be placed at the same time as the lift.
AlexandriaAges 20–60 - NCT07330609Recruiting
Gum and bone graft study for dental implants
This trial tests whether using a small piece of tissue from your own body can improve the gum around dental implants. It might help if you have thin or narrow gum tissue.
Kütahya, MerkezAges 1.5 years+ - NCT07717229Recruiting
Biofeedback and VR for kids during dental injections
This trial tests if a video game-like biofeedback tool (BrightHearts) or virtual reality can help children feel calmer during a numbing injection for dental work. It may be a good fit for healthy kids ages 7–12 who need a shot in the lower jaw.
GizaAges 7–12 - NCT06099717Recruiting
Testing a two-tooth dental bridge on one implant
This study tests if a special bridge supported by a single implant can replace three missing back teeth. It may help people who have a large enough jawbone and good overall health.
Goiânia, GoiásAges 18 years+ - NCT07661277Enrolling by invitation
Success rate of cheekbone mini-screws for braces
This study tests how well tiny screws placed in your upper cheek area work to support braces and move teeth into the right position. It is for adults aged 19 to 35 who need fixed braces on their upper teeth and have not had braces before.
DhakaAges 19–35 - NCT07671950Recruiting
Deep brain stimulation for neuropathic dental pain
This trial studies whether deep brain stimulation (DBS) can help people with a type of nerve-related tooth pain called atypical odontalgia. It is for those who have not found relief from standard treatments like medications or injections.
Vancouver, British ColumbiaAges 19–80 - NCT07672847Enrolling by invitation
Denture cleaners and their effect on milled denture materials
This study tests how different denture cleaning solutions affect the surface of two special types of denture materials (PMMA and PEEK) that are made by computer-controlled milling. It aims to see if these cleaners cause wear or damage over time.
Shibīn al KawmAges Any age - NCT07611461Enrolling by invitation
How Dental Crowns Affect Gum Health Long-Term
This study follows patients who receive tooth-colored metal crowns to see how these dental restorations affect the health of gums and supporting tissues over time. Understanding this helps dentists place crowns in ways that keep your mouth healthiest.
Riga, Dzirciema Iela 20Ages 20–75 - NCT07642596Recruiting
Root Canal Treatment Methods and Post-Procedure Pain
This study compares two different techniques for cleaning and shaping root canals (the nerve chambers inside teeth) to see which one causes less pain after treatment. If you have a dead nerve in a back lower tooth, this trial may help us understand the best way to treat it with minimal discomfort.
Eskişehir, OdunpazarıAges 18–65 - NCT07589751Enrolling by invitation
Comparing dental materials after tooth extraction
This study compares different biomaterials (artificial materials that work with your body) placed in the socket after a tooth extraction to see which one works best for healing. You would need to have a non-molar tooth removed and be willing to let researchers track how well different materials help your mouth heal.
Porto Alegre, Rio Grande do SulAges 18–65 - NCT07555366Recruiting
Healing after tooth extraction: two treatment approaches
This study compares two treatments applied to the socket (the hole left after a tooth is removed) to help it heal better. One treatment uses a product called microRepair, and the other uses chlorhexidine, a common antimicrobial rinse. The goal is to see which helps the extraction site heal faster and with fewer problems.
Roma, RMAges 18–75 - NCT07562334Recruiting
Cheekbone Implants With Two Tissue Coverage Methods
This trial compares two ways to cover and support cheekbone implants (zygomatic implants) in patients with severe upper jaw bone loss. The study tests whether a natural fat pad from your cheek or a special fibrin product (made from your own blood) works better to protect the implant and keep soft tissue thickness stable.
Cairo, Cairo GovernorateAges Any age
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 2,058 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,961 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.