Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 1,962 recruiting studies in this area right now.
By phase
- Not applicable1,544
- Phase 2144
- Phase 384
- Phase 182
- Phase 460
- Phase 1/Phase 235
- Phase 2/Phase 313
Top conditions
- Periodontitis103
- Nasopharyngeal Carcinoma74
- Periodontal Diseases50
- Dental Caries46
- Head and Neck Cancer35
- Gingivitis34
- Oral Cancer32
- Periodontal Disease29
- Dental Implant28
- Gingival Recession25
- Alveolar Bone Loss24
- Nasopharyngeal Carcinoma (NPC)24
- Sjogren's Syndrome24
- Tooth Loss24
- Temporomandibular Disorders (TMD)22
- Oropharynx Cancer21
- Peri-Implantitis21
- Temporomandibular Joint Disorders20
Leading sponsors
- Cairo University77
- Sun Yat-sen University50
- Mansoura University25
- Ain Shams University24
- Postgraduate Institute of Dental Sciences Rohtak24
- Tanta University24
- Al-Azhar University23
- Universidad Complutense de Madrid16
- University of Baghdad16
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California44
- Texas26
- Maryland21
- Massachusetts21
- Florida20
- New York19
- Pennsylvania19
- Ohio18
- Alabama17
- Michigan15
Recruiting studies1,962 total
- NCT06354712RecruitingPhase 2
Can N-acetylcysteine prevent mouth sores during radiation?
This study tests whether a medicine called N-acetylcysteine (NAC) can prevent mouth sores caused by radiation therapy for head and neck cancer. If you are starting radiation, this trial may help protect your mouth from painful side effects.
Al MansurahAges 18–80 - NCT07484685Recruiting
Earlier implant placement after tooth preservation
This study tests if placing a dental implant sooner (about 6-8 weeks after tooth removal and socket preservation) works well with a specific implant type. It is for people who need to replace a single front tooth, canine, or premolar and have good bone and gum health.
Guayaquil, GuayasAges 18 years+ - NCT07488416Recruiting
Ginger paste vs. antibiotics for infected baby molars
This study tests a new paste made from zinc oxide and gingerol (a ginger extract) to treat infected baby molars. It may be an alternative to the standard antibiotic paste, with fewer antibiotics and potentially fewer side effects.
CairoAges 4–8 - NCT07483086Recruiting
Implant position for thin gum patients
This study tests whether the vertical position of a dental implant affects bone loss around it, specifically for people with thin gums. If you are missing a single upper front tooth or premolar, you may be a candidate.
CairoAges 18 years+ - NCT07486609Enrolling by invitation
Comparing tests for jaw joint pain diagnosis
This study compares two different ways to diagnose jaw joint (TMJ) problems: a jaw-motion analyzer and an MRI. It aims to see which method is more accurate for people with ongoing face or jaw pain.
CairoAges 18–50 - NCT07487272Recruiting
Cell mapping in gum disease tissues
This study looks at the cells in gum tissue from people with different types of periodontitis (aggressive or chronic) and healthy gums. By understanding which cells are active and how they interact, researchers hope to find better ways to diagnose or treat gum disease.
Hangzhou, ZhejiangAges 20–40 - NCT06778590Recruiting
Comparing two ways to remove lower wisdom teeth
This study compares two methods for removing lower wisdom teeth before they are fully grown. It uses a special ultrasound tool (piezoelectric) versus traditional surgical tools to see which is gentler and leads to faster healing.
CatanzaroAges 14–24 - NCT06771427Recruiting
Exosomes for Sjogren's and Dry Eye
This study looks at tiny particles called exosomes in tears to find new ways to diagnose or treat Sjogren's syndrome and dry eye disease. It may help people with these conditions by learning more about what causes them.
Taipei, TaiwanAges 20–75 - NCT06776471Recruiting
Sealant study for children with weak enamel
This study compares two types of dental sealants applied to the first permanent molars of children aged 6-12 who have a condition called molar incisor hypomineralization (MIH), which means their back teeth have soft or chalky spots. The goal is to see which sealant works better at protecting these teeth from cavities.
AnkaraAges 6–12 - NCT06779578Recruiting
Comparing two types of radiofrequency for trigeminal neuralgia
This study compares two treatments (bipolar vs monopolar pulsed radiofrequency) for people with trigeminal neuralgia that hasn't improved with medication. It aims to see which method provides better pain relief.
AlexandriaAges Any age - NCT07474662Recruiting
Online vs. in-person physiotherapy for jaw muscle pain
This trial compares online physiotherapy sessions with face-to-face visits to see which works better for treating jaw muscle pain (myalgia). It aims to find a more convenient way to get care for this common condition.
Budapest, Pest CountyAges 18 years+ - NCT07479290RecruitingPhase 1
Vitamin D gel to speed up tooth movement after extraction
This trial tests whether applying vitamin D near the extraction site can speed up how quickly your canine teeth move into the gap after premolars are removed. It might help shorten your orthodontic treatment.
Islamabad, FederalAges 13 years+ - NCT07477873Enrolling by invitation
Emotions and jaw surgery recovery study
This study looks at how patients feel emotionally and physically before and after jaw surgery. It uses special software and questionnaires to track emotions, and checks the jaw joint and muscles after surgery. The goal is to see how these relate to recovery in patients having planned jaw surgery.
Kaunas, KaunoAges 18 years+ - NCT07474493Recruiting
Best ways to clean full-arch implant-supported teeth
This study compares different cleaning tools for people who have replacement teeth attached to implants across a full arch. It aims to find the easiest and most effective way to keep your new teeth clean and healthy.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06782035Recruiting
Effect of dressings on donor site comfort after gum graft surgery
This trial tests whether special dressings applied to the area where a gum graft is taken from can improve patient comfort and quality of life after surgery.
IzmirAges 18–85 - NCT06585566Recruiting
Bone graft trial for children with cleft palate
This trial tests a new way to repair a gap in the upper jawbone (called an alveolar cleft) using thin layers of bone, called cortical shells, taken from the patient's own body. It is for children who have not had this surgery before and who are generally healthy.
CairoAges 8–15 - NCT06789458Recruiting
Pro-resolution mediators in severe gum disease before and after treatment
This study looks at natural substances in your blood that help reduce gum inflammation. Researchers want to see how these substances change after standard gum disease treatment, which may lead to better ways to manage severe periodontitis.
Manial, Cairo GovernorateAges 18–80 - NCT07471555Enrolling by invitation
Vascular access and intraosseous study for nursing students
This trial tests a teaching method for inserting a special needle into bone (intraosseous access) and regular IV lines. It is only for 4th year nursing students.
Valencia, ValenciaAges 18 years+ - NCT07464197Recruiting
Tooth whitening with custom 3D-printed trays
This study tests if 3D-printed whitening trays work as well as regular custom trays. You'll use a whitening gel at home for a short time to see how white your teeth get.
Sant Cugat del Vallès, BARCELONAAges 18 years+ - NCT07465952Recruiting
Do price cuts help people get preventive dental care?
This trial tests whether offering different price discounts on dental check-ups encourages people who haven't been to the dentist recently to schedule a preventive visit. You may be eligible if you have a medical appointment soon and have not seen a dentist in the last 6 months.
SantiagoAges 18–70 - NCT07463859Recruiting
Treating gum disease and bad breath in diabetes patients
This trial tests whether combining standard gum treatment with a light-activated therapy can reduce bad breath in people with type 2 diabetes and advanced gum disease.
Bauru, São PauloAges 18–70 - NCT07465978Recruiting
Testing printed hybrid resin for dental overlays
This trial tests a special printed material used for tooth overlays (caps that cover the entire top of a back tooth). If you need a full overlay on a molar that has had root canal treatment, this study may be a good fit.
Sant Cugat del Vallès, BarcelonaAges 18 years+ - NCT07471386Recruiting
Gum graft for implant infection
This trial tests whether adding gum tissue around a dental implant helps treat an infection around the implant. It may be a good fit if you have a dental implant with inflammation and very little attached gum.
AnkaraAges 18–75 - NCT07466641Recruiting
Low-level laser or Piezocision to speed up canine tooth movement
This trial compares two treatments to see if they can safely speed up a specific tooth movement during braces. It tests a low-level laser or a minor surgical procedure called Piezocision against standard care.
Cairo, Cairo GovernorateAges 18–25
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 1,962 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,741 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.