Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 2,057 recruiting studies in this area right now.
By phase
- Not applicable1,634
- Phase 2148
- Phase 183
- Phase 381
- Phase 459
- Phase 1/Phase 236
- Phase 2/Phase 316
Top conditions
- Periodontitis108
- Nasopharyngeal Carcinoma80
- Periodontal Diseases57
- Dental Caries49
- Gingivitis35
- Oral Cancer35
- Head and Neck Cancer34
- Dental Implant30
- Sjogren's Syndrome29
- Gingival Recession27
- Periodontal Disease27
- Alveolar Bone Loss23
- Nasopharyngeal Carcinoma (NPC)23
- Peri-Implantitis23
- Tooth Loss22
- Oropharynx Cancer21
- Temporomandibular Disorders (TMD)21
- Trigeminal Neuralgia21
Leading sponsors
- Cairo University91
- Sun Yat-sen University52
- Ain Shams University30
- Mansoura University30
- Postgraduate Institute of Dental Sciences Rohtak24
- Al-Azhar University23
- Tanta University23
- University of Baghdad19
- Universidad Complutense de Madrid18
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California39
- Texas27
- Massachusetts22
- Ohio22
- Pennsylvania22
- New York20
- Maryland19
- Florida18
- Alabama16
- Michigan15
Recruiting studies2,057 total
- NCT06074952Recruiting
Color stability of denture teeth in staining solutions
This trial tests how well different acrylic denture teeth keep their color when soaked in various staining liquids. It uses only specific front teeth (maxillary central incisors) that are flat on the surface and made of a special acrylic called IPN.
Karachi, SindhAges Any age - NCT06048042RecruitingPhase 4
Comparing tooth graft vs bone graft for gum disease bone loss
This trial tests if using a tooth that is removed (like a wisdom tooth) to fill deep gum pockets works as well as using a piece of your own bone. It may help rebuild the bone around a damaged tooth.
CairoAges 18–50 - NCT06031298RecruitingPhase 4
Healing times for preserving jawbone after tooth extraction
This study tests if using a special type of bone graft made from a patient's own tooth can help preserve the jawbone after a tooth is removed. It compares different healing times to see which works best for keeping the bone strong for a future dental implant.
CairoAges 20–50 - NCT06012071Recruiting
Zirconia implants for a missing upper premolar
This trial tests two types of zirconia (ceramic) dental implants for replacing a single missing upper premolar. It aims to see which implant platform works best for long-term stability.
LjubljanaAges 25 years+ - NCT05676827Enrolling by invitation
Study pain and stress in people with long-term jaw muscle pain
This trial looks at how long-lasting jaw (masticatory) muscle pain relates to the nervous system and emotional stress. It may help researchers understand why symptoms persist and guide future treatments.
WroclawAges 18–80 - NCT05743127Recruiting
3D-printed vs lab-made braces expanders for kids
This study compares two types of orthodontic expanders—one made with 3D printing and one made in a lab—to see which works better for widening the upper jaw. It may help your child’s orthodontic team learn the best option for correcting a narrow upper palate.
Pittsburgh, PennsylvaniaAges 8–13 - NCT05758337Recruiting
Vibration therapy to help after sinus dental implant surgery
This trial studies whether a vibration-based treatment (vibropneumostimulation) can improve healing and implant success after dental implant surgery that also involved sinus lifting. It may be most helpful if you have had prior implant failures or risk factors that make implants harder to keep stable.
SamaraAges Any age - NCT05851963Recruiting
Toothbrushing help for teens with fixed braces
This study looks at whether using specific toothbrushes in daily life can improve dental gum and tooth health for teens with fixed braces. It may help by testing simple at-home brushing routines that could reduce gum problems during orthodontic treatment.
NancyAges 11–15 - NCT05716737Recruiting
Radiation treatment study for TMJ arthritis pain
This study looks at how radiotherapy (radiation treatment) may help people with arthritis in the jaw joint (TMJ). It will only consider patients whose TMJ arthritis was diagnosed by a dentist or surgeon and who have not had radiation to that area before.
ViennaAges 50–100 - NCT05584566Recruiting
Bone growth treatment before dental implants: two materials compared
This study compares two bone-building products used to repair a missing “bone wall” in the jaw so dental implants can be placed. You may be able to help find which material works better for guided bone regeneration and implant readiness.
JerusalemAges 18 years+ - NCT05500755Recruiting
Study testing PrimeTaper dental implants with x-ray follow-up
This study looks at outcomes of Dentsply Sirona PrimeTaper dental implants after placement. It includes people who already received at least one of these implants and evaluates results using dental x-rays.
Alicante, AlicanteAges 18–99 - NCT05272254RecruitingPhase 2
Povidone iodine in kids’ dental cavities surgery
This trial tests whether povidone iodine helps prevent problems or improves outcomes when children with severe early childhood cavities need dental treatment in the operating room. You may be able to join if your child fits the age and dental needs and has no iodine-related or thyroid problems.
Rochester, New YorkAges 2 years–5.9 years - NCT05399589Recruiting
Dental implant study using Nobel parallel implants in back teeth
This trial looks at how well a specific type of dental implant works in the back of the mouth (upper or lower). It may help patients by testing whether this implant-and-connector setup leads to good results without needing extra bone procedures.
Hangzhou, ZhejiangAges 18–70 - NCT05442034RecruitingPhase 1/Phase 2
Two gum treatments for deep bone defects in teeth
This study tests whether one of two treatments can improve healing of “intra-bony” gum/bone defects around teeth after deep cleaning. It may help some people with periodontal disease who have pockets deep enough to involve the bone but with certain health and dental conditions.
Davie, FloridaAges 18 years+ - NCT05638373Recruiting
Compare tooth color matching after bleaching using two filling types
This study looks at which dental filling material matches your tooth color better after you get your teeth bleached. It may help you and your dentist choose the best way to restore a front tooth area (class IV) so it blends naturally.
CairoAges 18–45 - NCT05495490Recruiting
Bone-building vs sinus lift for delayed dental implants
This trial compares two surgical methods to help place dental implants in the upper back jaw when there isn’t enough bone height. It may help you and your dentist choose the safest approach to create enough support for the implant.
AsyutAges 18–40 - NCT05565157Recruiting
Robotic placement of cheek-bone dental implants without flaps
This trial studies a robot-guided technique to place implants in the upper jaw using cheek-bone support, without making large gum flaps. It may help people who have severe bone loss in the upper jaw by improving how implants are placed after missing teeth or jaw injuries/surgery.
AmiensAges 18 years+ - NCT05426616Recruiting
Compare two dental membranes to help new bone grow
This trial tests two types of protective membranes placed during a bone-grafting procedure to help your upper-front jaw (anterior maxilla) rebuild bone. You might benefit if you have a tooth gap where a tooth was removed at least 3 months ago.
Ghent, Oost-VlaanderenAges 21 years+ - NCT05326880Recruiting
Long-term follow-up comparing zirconia and titanium dental implants
This study checks how well two kinds of dental implants (zirconia and titanium) work over 5 years in replacing a single tooth. You may be included if you already received the specific implant type and restoration the study requires and you can attend regular checkups.
DüsseldorfAges 18 years+ - NCT05362136Recruiting
Sinus lift with different perforations to grow new bone
This trial studies how many small openings (perforations) are made in the sinus floor during a sinus lift procedure, to see which approach helps form more new bone. You might consider it if you need sinus floor elevation on both sides for dental bone support.
ViennaAges 18–120 - NCT04743362Recruiting
Noninvasive scans for skin and mouth lesions
This trial tests noninvasive imaging methods to look at skin and mouth (mucosal) conditions. It may help doctors better see changes in these areas without taking tissue samples.
New York, New YorkAges Any age - NCT04863222RecruitingPhase 4
Compare MTA vs Biodentine for baby molar pulp care
This trial compares two tooth materials (MTA and Biodentine) used during pulpotomy or indirect pulp cap procedures for children with early decay in baby molars. It looks at how well the tooth heals over time using symptoms and follow-up dental X-rays.
Danville, PennsylvaniaAges 2–12 - NCT04927819Recruiting
Extra-short versus standard dental implants in a fixed bridge
This study compares extra-short dental implants versus standard-length implants when they are joined together in the same fixed bridge. It may help people understand which implant type works better for supporting a stable multi-tooth replacement.
Vitoria-GasteizAges 18 years+ - NCT06783660Recruiting
Graft material for preserving tooth socket after extraction
This trial tests a new collagen-based graft material used to preserve the bone socket right after a tooth is removed. The goal is to keep the bone healthy so that a dental implant can be placed later.
Korea, SeoulAges 19–75
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 2,057 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,953 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.