Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 1,957 recruiting studies in this area right now.
By phase
- Not applicable1,542
- Phase 2142
- Phase 384
- Phase 181
- Phase 460
- Phase 1/Phase 235
- Phase 2/Phase 313
Top conditions
- Periodontitis103
- Nasopharyngeal Carcinoma73
- Periodontal Diseases50
- Dental Caries45
- Head and Neck Cancer35
- Gingivitis33
- Oral Cancer31
- Periodontal Disease29
- Dental Implant28
- Gingival Recession25
- Alveolar Bone Loss24
- Nasopharyngeal Carcinoma (NPC)24
- Sjogren's Syndrome24
- Tooth Loss24
- Temporomandibular Disorders (TMD)22
- Oropharynx Cancer21
- Peri-Implantitis21
- Temporomandibular Joint Disorders20
Leading sponsors
- Cairo University77
- Sun Yat-sen University50
- Mansoura University25
- Ain Shams University24
- Postgraduate Institute of Dental Sciences Rohtak24
- Tanta University24
- Al-Azhar University23
- Universidad Complutense de Madrid16
- University of Baghdad16
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California44
- Texas26
- Maryland21
- Massachusetts21
- Florida20
- New York19
- Pennsylvania19
- Ohio18
- Alabama17
- Michigan15
Recruiting studies1,957 total
- NCT06457776Recruiting
Jaw bone health in people taking bone-strengthening drugs
This study looks at how a specific jaw problem (osteonecrosis) may happen in people taking bone-strengthening medications. It aims to better understand and manage this side effect.
RomaAges 18 years+ - NCT07829328Enrolling by invitationPhase 4
Can a special rinse help prevent early cavities between teeth?
This trial tests a special rinse called SAP P11-4 to see if it can stop or reverse early cavities between teeth before they need fillings. It may help keep your teeth healthy without more involved dental work.
Schofield Barracks, HawaiiAges 18–74 - NCT07830836Enrolling by invitation
Physiotherapy and osteopathy for recent neck, back, or jaw pain
This study tests whether physiotherapy and osteopathic treatment can help relieve recent (acute) pain in the neck, lower back, or jaw joint. It aims to understand if these hands-on therapies reduce pain and improve jaw function.
Gorzów Wielkopolski, Lubusz VoivodeshipAges 20–40 - NCT07827833Recruiting
Dental fillings and crowns for children under general anesthesia
This study looks at how well dental fillings and crowns hold up in children who get all their dental work done in one visit while asleep with general anesthesia. It aims to see which restorations work best over 24 months.
TantaAges 3–6 - NCT07828041Recruiting
Jaw surgery and how it affects jaw joint movement
This study looks at how corrective jaw surgery changes how your jaw joint works. If you are planning to have jaw surgery to correct a severe bite or facial imbalance, this research may help doctors understand the effects on jaw movement.
BudapestAges 18 years+ - NCT07828509Enrolling by invitation
Study on long-term problems with metal-ceramic crowns
This study looks at metal-ceramic crowns (tooth caps made with a metal base and ceramic coating) to see what problems might happen years after they are placed. If you have such a crown, you might be asked to have a check-up and fill out a questionnaire.
RigaAges 20–80 - NCT07826728Recruiting
Smoking and gum fluid proteins in gum health and disease
This study looks at how smoking affects certain proteins in the fluid around your teeth, which are linked to gum disease and inflammation. It may help find better ways to treat gum problems in smokers.
Bolu, CentralAges 18–65 - NCT06455410RecruitingPhase 2
GP plus adebrelimab vs. chemo alone for nasopharyngeal cancer
This trial tests a new combination of chemotherapy drugs (GP) plus an immunotherapy drug (adebrelimab) before standard treatment for nasopharyngeal cancer. It aims to see if this combination works better than chemotherapy alone for shrinking tumors.
Foshan, GuangdongAges 18–65 - NCT06445088Recruiting
Testing a new EBV DNA test for nasopharyngeal cancer
This trial is testing a new way to diagnose nasopharyngeal cancer using a special test that looks at a change in the EBV virus DNA. It is for people who may have symptoms of this cancer or have tested positive for EBV, but have not yet been treated.
Fuzhou, FujianAges Any age - NCT06338735Recruiting
High-frequency ultrasound for Sjögren's diagnosis
This study uses a special, very high-frequency ultrasound to take detailed images of the small glands that can be affected in Sjögren's syndrome. The goal is to see if this new ultrasound technique can help doctors diagnose Sjögren's more accurately.
PisaAges 18 years+ - NCT07825415Recruiting
Understanding pulpitis severity to improve tooth-saving treatment
This study looks at whether markers of inflammation in the dental pulp (the nerve and blood vessels inside the tooth) can predict how well a tooth-saving procedure called full pulpotomy works for molars with very deep cavities. If successful, this could help doctors choose the best treatment for severe tooth pain.
Rohtak, HaryanaAges 18–40 - NCT07819656Recruiting
Predicting severe blood cell drops in nasopharyngeal cancer
This study looks at how likely it is for people with nasopharyngeal carcinoma to experience a severe drop in blood cell counts (myelosuppression) during treatment. By tracking risk, doctors may be better able to prevent or manage this side effect.
Guangzhou, GuangdongAges 18 years+ - NCT07824921Enrolling by invitation
Oral microbiome in aorta aneurysm and carotid atherosclerosis
This study looks at how bacteria in your mouth might be linked to the health of your blood vessels. It may help doctors understand why some people get aneurysms or blocked arteries, and could lead to better ways to prevent or treat these conditions.
BudapestAges 18–110 - NCT07824518Recruiting
Comparing two bone graft materials after wisdom tooth removal
This study compares two types of bone graft material used to help healing after removing impacted lower wisdom teeth. It tests whether a graft made from your own tooth works as well as one from a cow (bovine xenograft).
Madrid, MadridAges 18 years+ - NCT07822269Recruiting
Magnifying tools for deep teeth cleaning
This study compares two types of magnifying tools used during deep cleaning of teeth and gums. It aims to see if one tool is better at removing plaque and tartar, which may help treat gum disease.
AnkaraAges 18 years+ - NCT07817498Recruiting
Comparing two attachment types for implant-supported dentures
This study compares two different types of attachments (MK1 and Clip) used to hold a lower denture in place with four dental implants. It looks at how they affect bacteria in the mouth, which may help in choosing the better attachment for better oral health.
Al MansurahAges 45–65 - NCT07818447Recruiting
Different ways to preserve bone after tooth removal
This study compares different ways to preserve the bone where a tooth is removed, which may help keep the area ready for future implants or other dental work. If you're having a tooth pulled due to gum disease, this trial could help maintain your jawbone and support better healing.
Thessaloniki, ThessalonikiAges 18 years+ - NCT07819240Recruiting
Antibacterial tooth medications for acute root abscess
This trial tests how well different antibacterial medications placed inside the tooth during root canal treatment clear infection in people with a severe tooth abscess. It aims to find the most effective way to reduce bacteria and relieve symptoms.
Erzurum, ErzurumAges 18–65 - NCT07823374Recruiting
Gum graft attachment: tacks vs. stitches
This study compares two ways to attach a gum graft during surgery: using small tacks or using stitches. It aims to see which method works better for healing and comfort.
Giza, Giza GovernorateAges 18–40 - NCT06043453Recruiting
Revitalizing injured, growing permanent teeth
This trial tests a new approach to help injured, still-growing permanent teeth heal and continue to develop naturally. It may be an option if your child has a traumatized tooth with an infection and the root is not yet fully formed.
GhentAges 6–18 - NCT06301165RecruitingPhase 2
Chemotherapy comparison for advanced nasopharyngeal cancer
This trial compares two different chemotherapy combinations given before radiation for nasopharyngeal cancer. It is for patients with advanced but not metastatic disease who are in good overall health.
Guangzhou, GuangdongAges 18–65 - NCT07810530RecruitingPhase 2
Mouthwash with laser for preventing mouth sores in stem cell transplant
This study tests whether a special mouthwash made from copaiba (a natural oil) plus low-level laser therapy can prevent mouth sores caused by high-dose chemotherapy before a stem cell transplant. It might help reduce pain and trouble eating during your transplant treatment.
Rio de Janeiro, Rio de JaneiroAges 12 years+ - NCT07812883Recruiting
Preserving jawbone after tooth removal
This study tests a technique to preserve the jawbone after a tooth is removed, so there is enough bone left to place a dental implant later. It may help people who need a tooth extraction and want to get a dental implant in the future.
Santiago, Santiago MetropolitanAges 18 years+ - NCT07809334Enrolling by invitation
Surgical treatment for infected dental implants in smokers
This trial tests a surgical treatment for dental implant infections (peri-implantitis) in patients who smoke. It aims to see how well the implant survives after surgery to fix the infected area.
TorinoAges 18 years+
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 1,957 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,729 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Hormones & metabolism
- Mental health
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- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.