Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 1,957 recruiting studies in this area right now.
By phase
- Not applicable1,542
- Phase 2142
- Phase 384
- Phase 181
- Phase 460
- Phase 1/Phase 235
- Phase 2/Phase 313
Top conditions
- Periodontitis103
- Nasopharyngeal Carcinoma73
- Periodontal Diseases50
- Dental Caries45
- Head and Neck Cancer35
- Gingivitis33
- Oral Cancer31
- Periodontal Disease29
- Dental Implant28
- Gingival Recession25
- Alveolar Bone Loss24
- Nasopharyngeal Carcinoma (NPC)24
- Sjogren's Syndrome24
- Tooth Loss24
- Temporomandibular Disorders (TMD)22
- Oropharynx Cancer21
- Peri-Implantitis21
- Temporomandibular Joint Disorders20
Leading sponsors
- Cairo University77
- Sun Yat-sen University50
- Mansoura University25
- Ain Shams University24
- Postgraduate Institute of Dental Sciences Rohtak24
- Tanta University24
- Al-Azhar University23
- Universidad Complutense de Madrid16
- University of Baghdad16
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California44
- Texas26
- Maryland21
- Massachusetts21
- Florida20
- New York19
- Pennsylvania19
- Ohio18
- Alabama17
- Michigan15
Recruiting studies1,957 total
- NCT07852806Recruiting
Bone marrow cells for repairing severe jaw bone defects
This trial tests whether using your own bone marrow cells can help repair severe bone loss in the jaw. It may offer a new way to rebuild bone for people who need a bone graft.
Nanjing, JiangsuAges 16–60 - NCT07851857RecruitingPhase 3
Short course of antibiotics after head and neck cancer surgery
This trial tests whether giving antibiotics for one day after head and neck surgery works just as well as giving them for longer to prevent infections. It might help you have a smoother recovery with fewer side effects from antibiotics.
São Paulo, São PauloAges 18 years+ - NCT05710952Recruiting
Orthodontic braces study and how they affect jaw joints
This study looks at whether multi-attachment orthodontic treatment (either on the front or back of teeth) changes the temporomandibular joint, which is the jaw joint. The researchers will assess your jaw joint using a tool called Modjaw.
MontpellierAges 18 years+ - NCT06430762Recruiting
Study of risk factors for jaw bone damage from certain drugs
This study looks at people who have jaw bone damage (osteonecrosis) caused by medications. Researchers want to understand what treatments and risk factors are linked to this condition to help improve care.
IstanbulAges 18–110 - NCT07842991RecruitingPhase 3
A toothpaste for reducing plaque and improving gum health
This study tests a new toothpaste designed to reduce dental plaque (the sticky film on teeth) and help prevent gum problems like bleeding or swelling. If you have mild gum issues, you may be able to join and use the toothpaste for six months.
Roma, RomeAges 18–70 - NCT07847541RecruitingPhase 2
Botulinum toxin injections for jaw muscle pain
This trial tests whether botulinum toxin (Botox) injections can reduce pain in the jaw muscles for people with temporomandibular joint (TMJ) disorders that haven't improved with other treatments. It may help if you have ongoing jaw pain and muscle tightness.
IslamabadAges 18–60 - NCT07845110Recruiting
Fluoride varnish with laser for early tooth spots in baby teeth
This study tests whether two types of fluoride varnish, with or without a special laser, can help reverse early white spots on baby teeth in children aged 3 to 6. It aims to find the best way to remineralize these spots and prevent cavities.
Alexandria, Alexandria GovernorateAges 3–6 - NCT07850674Recruiting
Spinal stiffness and fear of movement in Parkinson's
This study looks at how Parkinson's disease affects neck and back movement, stiffness, and fear of movement, in relation to jaw joint problems. The results may help improve therapies that target flexibility and quality of life.
HatayAges 35–75 - NCT07845019Recruiting
Comparing two ways to place front tooth implants
This study compares two ways of placing a dental implant right after a front tooth is removed. The goal is to find which method better keeps bone and gum tissue, helping your implant look and feel natural.
Minya, Minya GovernorateAges 20–40 - NCT07850167Recruiting
Pain during root canal treatment across menstrual stages
This study looks at how the menstrual cycle and menopause may affect pain during root canal treatment. It aims to help dentists better manage pain for women.
NiğdeAges 18 years+ - NCT07845006Enrolling by invitationPhase 1
Smart scaffold for gum and bone healing
This early study tests a new smart scaffold for rebuilding the tissue that supports your teeth. It uses artificial intelligence to design a better healing material, which might help your gums and bone grow back stronger.
GizaAges Any age - NCT07843381Recruiting
Testing a new drug for Sjögren's syndrome with lung disease
This clinical trial tests a new drug called telitacicept for people who have both Sjögren's syndrome and interstitial lung disease. The drug aims to reduce the immune system's attack on your body and may help improve lung symptoms.
BeijingAges 18–70 - NCT07848542Recruiting
Using virtual reality or weighted blankets to ease kids' dental anxiety
This trial tests whether using virtual reality glasses or a weighted blanket can help reduce children's anxiety during dental procedures that involve numbing. It aims to make dental visits more comfortable for kids who are very fearful of dental treatment.
Istanbul, FatihAges 5–9 - NCT06444776Recruiting
Taste and saliva changes during radiotherapy for head & neck cancer
This study looks at how radiation therapy for head and neck cancer changes your sense of taste and saliva. It aims to better understand and manage these side effects.
Aarau, Canton of AargauAges 18 years+ - NCT06080633Recruiting
Facial prediction tech for people with no teeth
This study tests a new facial prediction technology that helps create better-fitting dentures for people with no natural teeth. It may improve how your dentures look and feel.
Leuven, HeverleeAges 50–100 - NCT07836998Recruiting
Mouthwash plus whitening toothpaste for stain removal
This study tests an experimental mouthwash used with a regular whitening toothpaste to see if it helps remove surface stains from teeth. This could help people who have stains from coffee, tea, or tobacco.
Melbourne, FloridaAges 18–65 - NCT07842042Recruiting
Toothpaste study for gum health
This study tests a toothpaste with stannous fluoride to see how it affects gum health by measuring certain markers in the fluid around the teeth. It may help reduce gum inflammation and improve oral hygiene.
BirminghamAges 18–70 - NCT07841158Recruiting
Rebuilding jawbone for dental implants
This trial tests a new material to rebuild the jawbone where it has thinned out, so it can hold a dental implant. It may help people who need a stronger jawbone for tooth replacement.
Giza, Giza GovernorateAges 21 years+ - NCT07842120RecruitingPhase 2
Can certain medications speed up tooth movement with braces?
This study tests three different treatments (MOP, prostaglandin E1, and calcitriol) to see if they can make teeth move faster during orthodontic treatment. If you're getting braces for moderate crowding, this could reduce your treatment time.
Baghdad, Baghdad GovernorateAges 18–25 - NCT07838051Recruiting
Muscle relaxants for sore throat after breathing tube
This study tests whether giving muscle relaxants during surgery can reduce sore throat after using a special breathing tube called a video laryngeal mask airway. It may help people who are having longer surgeries and have a higher body mass index.
Samsun, SamsunAges 18–70 - NCT07841067Recruiting
3D-printed vs. milled plates for jaw surgery
This study compares two types of titanium plates (3D-printed vs. traditionally milled) used to hold the upper jaw in place after corrective jaw surgery. It aims to see which type is more accurate and reduces surgery time, which could mean a faster recovery for you.
Cairo, New Cairo, Fifth SettlementAges 18 years+ - NCT07836920Recruiting
Comparing two tooth-restoration approaches after root canal treatment
This study compares two ways to restore teeth that have had root canals, focusing on back teeth. It aims to see which approach is more conservative and effective, which may help preserve more of your natural tooth and improve long-term outcomes.
Cairo, ManialAges 20–50 - NCT07836816Enrolling by invitation
Comparing two methods for moving canine teeth in braces
This study compares two ways of retracting the canine teeth after premolar removal to see which works faster or better. It may help us improve orthodontic treatment for people who need their upper canines pulled back.
DhakaAges 18–25 - NCT07836231Recruiting
Comparing two procedures for deep gum pockets
This study compares two surgical methods to treat deep gum disease pockets around teeth. Both methods aim to help the bone and gum heal better after treatment.
Giza, Giza GovernorateAges 18 years+
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 1,957 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,729 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.