Clinical trials
Acute Ischemic Stroke Patients clinical trials
Below are recruiting acute ischemic stroke patients clinical trials, each written for real people, not researchers. We’re tracking 406 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06320431RecruitingPhase 3
Clot-busting drug for disabling stroke within 4.5 hours
This trial tests a clot-busting drug called tenecteplase for people having a disabling ischemic stroke (a clot blocking blood flow to the brain). It aims to see if the drug can help improve recovery when given within 4.5 hours of symptoms starting.
Sydney, BarangarooAges 18 years+ - NCT06394180Recruiting
Study of perforations during clot removal for stroke
This trial looks at what happens when a hole (perforation) occurs in a brain artery during clot removal for stroke. It compares patients who had this complication to those who did not, to understand how to better manage it.
BaselAges 18 years+ - NCT06388148Recruiting
Clot removal for very large strokes
This trial tests a procedure to remove a large blood clot in the brain (mechanical thrombectomy) for people who have a very large stroke. It aims to see if removing the clot can improve recovery, even for those with severe strokes.
Hengyang, HunanAges 18 years+ - NCT06297863RecruitingPhase 2
Head-down position to improve blood flow in stroke
This study tests whether lying with your head tilted down 15 degrees can improve blood flow to the brain during a stroke. It is for people who have a clot in the middle cerebral artery and are already getting a procedure to remove the clot.
AvezzanoAges 18 years+ - NCT06241677Recruiting
Clot-busting therapy for stroke patients on blood thinners
This study tests whether giving a clot-busting medicine through an IV can help people who have had a stroke while taking a common blood thinner (apixaban, dabigatran, edoxaban, or rivaroxaban). It may be an option if your last dose of the blood thinner was 12 to 48 hours before the stroke and you arrive at the hospital within 4.5 hours of symptoms starting.
Hong KongAges 18 years+ - NCT06212674RecruitingPhase 4
Stroke prevention: combined heart procedure for atrial fibrillation
This study tests a combined approach — a catheter ablation to fix the irregular heartbeat (atrial fibrillation) and a device to close the left atrial appendage — in people who recently had a stroke caused by a clot. The goal is to prevent future strokes and reduce the need for long-term blood thinners.
Katowice, Upper SilesiaAges 18–75 - NCT06210633Recruiting
Clot removal trial for very large strokes
This trial tests a procedure called endovascular thrombectomy (clot removal through a catheter) for people with very large strokes. It aims to see if removing the clot can help even when a large part of the brain is already damaged.
Xiangtan, HunanAges 18 years+ - NCT06226805RecruitingPhase 2
Study of BB-031 for acute ischemic stroke
This trial tests a new drug called BB-031 for people who have had a stroke caused by a blocked blood vessel in the brain. The drug may help restore blood flow and reduce damage if given within 24 hours of symptoms starting.
Scottsdale, ArizonaAges 18 years+ - NCT06143488Recruiting
Clot removal versus medication for mild stroke with large vessel blockage
This trial compares a procedure to remove the blockage (endovascular therapy) with the best medications alone for people who have a mild stroke caused by a large blocked artery in the brain. The goal is to see if the procedure can improve recovery better than medicine alone.
Wuhu, AnhuiAges 18 years+ - NCT06155032Recruiting
Clot Removal for Worsening Mild Stroke
This trial tests whether emergency clot removal (endovascular therapy) can help people whose mild stroke gets worse within a week. It's for those who have a blockage in a large brain artery and enough healthy brain tissue to save.
Fuyang, AnhuiAges 18 years+ - NCT06129175RecruitingPhase 2/Phase 3
Stem cells for recent moderate to severe stroke
This trial is testing a new treatment using stem cells from donated umbilical cord tissue to help people recover from a recent moderate to severe stroke. It is for patients who cannot receive standard clot-busting treatments.
Cheras, Kuala LumpurAges 18 years+ - NCT06045156Recruiting
Tirofiban after clot-busting for stroke
This trial tests whether giving tirofiban (a blood thinner) shortly after the standard clot-busting drug tenecteplase can improve recovery from a moderate stroke. It is for people who have had a stroke within the last few hours and do not have certain risk factors like irregular heart rhythm or recent bleeding.
Changchun, JilinAges 18 years+ - NCT06010641Recruiting
Head-down position for stroke from large artery blockage
This trial tests if lying with the head lower than the body (head-down position) can help people who are having a stroke caused by a blockage in a large artery in the front part of the brain. The goal is to see if this simple position improves blood flow and reduces disability.
ShenyangAges 18 years+ - NCT06010628RecruitingPhase 4
Tenecteplase for stroke 4.5 to 6 hours after onset
This trial tests a medicine called tenecteplase (a clot-buster) for people who have a moderate or severe stroke caused by a clot and can be treated 4.5 to 6 hours after symptoms start. It aims to see if this medicine can help improve recovery.
Shenyang, None SelectedAges 18 years+ - NCT05976685Recruiting
Close the left atrial appendage after stroke despite blood thinners
This study tests whether closing a heart pouch called the left atrial appendage can prevent future strokes in people with atrial fibrillation who had an ischemic stroke even while taking blood thinners. It may help reduce stroke risk by blocking a common place where clotting can start.
BrugesAges 18 years+ - NCT05967728Enrolling by invitationPhase 2
Testing remote arm conditioning to protect the brain in stroke
This Phase 2 study tests whether a simple remote method that briefly reduces blood flow in the arm (called ischemic conditioning) can help people with brain small-vessel disease or an acute ischemic stroke. Participants are monitored by phone and, for stroke patients, through a Mobile Stroke Unit.
Calgary, AlbertaAges 55 years+ - NCT05970406Enrolling by invitation
High-intensity swallow therapy after ischemic stroke
This trial tests a more intensive swallow-therapy program for people with difficulty swallowing soon after an ischemic stroke. It may help improve safety and function when eating and drinking.
Baltimore, MarylandAges 18–99 - NCT05911568Recruiting
Clot-removal treatment for stroke patients with existing disability
This trial studies whether an endovascular (catheter-based) procedure to treat a certain type of blocked artery can improve outcomes for people who already had trouble functioning before their stroke. You may be considered if your stroke is confirmed early and your scans show the right type and location of blockage.
Birmingham, AlabamaAges 18 years+ - NCT05903560Recruiting
Arm versus leg access for clot removal in basilar stroke
This trial compares doing a clot-removal procedure through the arm artery versus the leg artery for an emergency stroke caused by a blocked basilar artery. It aims to see which access route is safer and more effective for restoring blood flow when time is critical.
Nanjing, JiangsuAges 18 years+ - NCT05847699Recruiting
MRI study of stroke brain changes after decompression surgery
This study looks at how MRI findings match what doctors see in brain tissue after treatment for a type of severe stroke. It may help researchers better understand which brain changes happen early and how decompressive surgery affects them.
ParisAges 18 years+ - NCT05871606RecruitingPhase 1
Breathing nitric oxide during clot-removal for stroke
This Phase 1 study tests whether inhaled nitric oxide (a gas breathed through a ventilator) can improve outcomes in people having a specific kind of emergency stroke procedure to remove a clot from the brain. It focuses on patients who need general anesthesia for the clot-removal procedure and have imaging results that suggest salvageable brain tissue.
Charlotte, North CarolinaAges 18–80 - NCT05363397RecruitingPhase 2
Adjunctive TBO-309 added to stroke clot removal treatment safety
This Phase 2 trial studies whether adding TBO-309 to standard emergency treatment for acute ischemic stroke is safe and tolerable. It may help researchers see if the added drug can be given without causing excessive side effects alongside clot-busting and/or clot-removal procedures.
Camperdown, New South WalesAges 18 years+ - NCT05760846Recruiting
Training hand skills after a recent stroke
This study looks at a therapy that helps people with a recent stroke relearn coordinated hand and arm movements. It compares how well motor skill learning works and may help improve functional use of the affected arm.
Yvoir, NamurAges 18–90 - NCT05691244RecruitingPhase 3
Tested drug for acute ischemic stroke within 24 hours
This Phase 3 trial studies sovateltide (and a placebo) in adults with an ischemic stroke, aiming to improve safety and outcomes. It focuses on people who can start treatment quickly after stroke symptoms begin and who do not have bleeding in the brain on imaging.
Tucson, ArizonaAges 18–80
Hear when a new Acute Ischemic Stroke Patients trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for acute ischemic stroke patients?
- Yes. Clin2 currently lists 406 recruiting acute ischemic stroke patients studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acute ischemic stroke patients trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acute ischemic stroke patients trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.