Clinical trials
Amyotrophic Lateral Sclerosis clinical trials
Below are recruiting amyotrophic lateral sclerosis clinical trials, each written for real people, not researchers. We’re tracking 186 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07268833Recruiting
Finding new ALS biomarkers from nerve cells and blood
This study looks for new ways to detect and understand ALS by analyzing tiny nerve and blood markers. It may help find better treatments for ALS and related nerve diseases.
Monserrato, CaliforniaAges 18 years+ - NCT02964637Recruiting
Tests to help diagnose frontotemporal dementia
This study looks at testing (including brain scans) to figure out what type of frontotemporal dementia or related language/speech condition a person has. It may help by making diagnoses more accurate, which can guide better care.
Toronto, OntarioAges 18–90 - NCT07235111Recruiting
Studying biomarkers for neurodegenerative diseases
This study is looking for people with neurodegenerative diseases (like Alzheimer's, Parkinson's, ALS) to help researchers find new markers in the body that could help understand these conditions better and possibly lead to better treatments.
Genoa, GenoaAges 18 years+ - NCT07224256Recruiting
Brain implant trial to help with communication after injury or disease
This trial tests a brain-computer interface (BCI) that is implanted by a robot. It is designed to help people who have lost the ability to speak clearly or use their hands well, due to conditions like ALS, stroke, or spinal cord injury.
Dallas, TexasAges 22–75 - NCT07213440Recruiting
Early markers for ALS study
This study looks for early signs of ALS in people with genetic risk, healthy controls, and people with early symptoms. It aims to find markers that could help diagnose ALS sooner.
Tours, FranceAges 18–90 - NCT06917924Recruiting
Tailored ALS trial using genetics and stem cells
This study aims to better understand ALS by looking at your genes, biomarkers, and stem cells. It may help develop treatments that are personalized to you.
MilanAges 18 years+ - NCT06765499Recruiting
Silkworm pupa powder for nutrition and frailty in motor neuron disease
This trial tests whether silkworm pupa powder can improve nutrition and reduce frailty in people with motor neuron disease (like ALS). It looks for volunteers who are frail, have a confirmed diagnosis, and are willing to provide blood, stool, and urine samples.
Hangzhou, ZhejiangAges 18–80 - NCT06318585Recruiting
Building a database for motor neuron disease research
This study collects information from people with ALS or other motor neuron diseases to better understand how these conditions vary. By joining a database, you help researchers find patterns that could improve care.
Milan, MIAges 18 years+ - NCT07142291RecruitingPhase 2
Cromolyn inhaler for early ALS
This trial tests if an inhaled drug called cromolyn can help people with early-stage ALS. It is for people who can still breathe well and are not yet using a ventilator.
Scottsdale, ArizonaAges 18–75 - NCT07127172Recruiting
Brain implant study for controlling devices with your mind
This study tests a brain implant that lets you control external devices like a computer or tablet just by thinking. It is for people with paralysis or severe weakness in both arms due to conditions like spinal cord injury, ALS, or stroke.
London, Greater LondonAges 18 years+ - NCT07095686Enrolling by invitationPhase 1/Phase 2
Personalized treatment for CHCHD10 ALS
This trial tests a personalized medicine approach for people with a specific genetic form of ALS caused by changes in the CHCHD10 gene. A custom-designed antisense oligonucleotide (a type of genetic therapy) is used to target the underlying cause of the disease.
New York, New YorkAges 18 years+ - NCT07067229Recruiting
Brain stimulation and exercise for motor neuron disease
This study tests whether combining non-invasive brain stimulation (a gentle, non-surgical treatment) with exercise can help people with motor neuron disease (MND). It may improve movement and quality of life for those with mild to moderate symptoms.
Bangkok, PathumwanAges 18–80 - NCT07017946RecruitingPhase 1/Phase 2
Gut bacteria transplant for fast-progressing ALS
This trial tests whether a transplant of healthy gut bacteria (called a microbiome transplant) can slow down ALS in people whose disease is progressing rapidly. It aims to see if changing the gut environment can help with symptoms and quality of life.
Durham, North CarolinaAges 18 years+ - NCT06700304Recruiting
Brain implant to help control devices with thoughts
This clinical trial tests a brain-computer interface (a small device implanted in the brain) that may help people with severe paralysis control external devices like a computer or tablet using only their thoughts. The study is for adults with paralysis from a spinal cord injury or ALS, and requires a stable caregiver.
Toronto, OntarioAges 19 years+ - NCT06992596Recruiting
Brain implant study for controlling devices with thoughts
This trial tests a brain implant that lets you control external devices using your thoughts. It's for people with limited arm function due to spinal cord injury, stroke, ALS, or similar conditions.
Abu DhabiAges 18 years+ - NCT06891716RecruitingEarly Phase 1
PET scan for TDP-43 proteinopathies
This study tests a new PET scan dye that may help see TDP-43 protein buildup in the brain, which is linked to certain dementias and ALS. It aims to improve diagnosis and tracking of these conditions.
AmsterdamAges 40–70 - NCT06881979Recruiting
High-tech rehab for chronic neuromuscular diseases
This study tests a high-tech rehabilitation program for people with long-term nerve and muscle conditions. It aims to help you improve your walking and daily function using advanced technology.
GenovaAges 18–80 - NCT06877143Recruiting
High-calorie PEG nutrition for ALS energy needs
This trial tests whether a special high-calorie formula given through a PEG tube can help people with ALS maintain energy balance and potentially slow disease progression. It is for adults with ALS who are already using a PEG tube for nutrition.
Ulm, Baden-WurttembergAges 18 years+ - NCT06875739Enrolling by invitation
Saliva test for early diagnosis of brain diseases
This study tests whether a saliva sample can help tell the difference between brain diseases like Alzheimer's, Parkinson's, and related conditions. By using a special laser technique, researchers hope to find a quick, non-invasive way to make an earlier and more accurate diagnosis.
CagliariAges 60–85 - NCT06841341Enrolling by invitation
Predicting breathing problems in ALS
This study uses ultrasound and electrical tests of breathing muscles and nerves to see if they can predict breathing failure in people with ALS. This could help doctors know when a patient might need breathing support.
Krakow, Lesser Poland VoivodeshipAges 18–80 - NCT06828523Recruiting
Interactive tasks and how we hear them
This study tests how listening to speech during interactive tasks affects what you hear. It may help us understand how people communicate in everyday situations.
University Park, PennsylvaniaAges 18–65 - NCT06819124Recruiting
Study on interactions between people with ALS and their caregivers
This study looks at how people with ALS and their caregivers talk and interact with each other. It may help researchers understand communication challenges and improve support for both.
University Park, PennsylvaniaAges 18–90 - NCT06782958Enrolling by invitationPhase 1
Safety study of FHND1002 granules in healthy adults
This trial tests a new medication called FHND1002 in healthy adults aged 18 to 45. The goal is to check its safety, how well the body tolerates it, and how it is processed. It is one of the first tests in humans.
Lanzhou, GansuAges 18–45 - NCT06735014Recruiting
ALS imaging study to track disease progression
This study uses MRI brain scans to understand how ALS affects the brain over time. It may help researchers develop better ways to measure the disease.
Gainesville, FloridaAges 18 years+
Hear when a new Amyotrophic Lateral Sclerosis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for amyotrophic lateral sclerosis?
- Yes. Clin2 currently lists 186 recruiting amyotrophic lateral sclerosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a amyotrophic lateral sclerosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a amyotrophic lateral sclerosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.