Clinical trials
Brain clinical trials
Below are recruiting brain clinical trials, each written for real people, not researchers. We’re tracking 2,059 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT02619890Recruiting
Brain tumor registry using clinical and brain scan information
This study collects information about people with brain gliomas, including what treatments they receive and what their brain scans show. It’s meant to help researchers better understand these tumors and how they respond to first- or second-line therapy.
SeoulAges 18 years+ - NCT02685969Recruiting
Brain scan study of amyloid and brain sugar use
This study uses brain imaging to measure two things in the brain—amyloid protein and how the brain uses sugar. It may help researchers better understand early brain changes in people in the ALFA project.
Barcelona, CataloniaAges 45–75 - NCT02793999Recruiting
Near-infrared monitoring to guide cooling in newborns
This study tests a special, non-invasive sensor (near-infrared light) to help doctors choose the best cooling treatment for some newborns after brain injury. It may improve how well cooling works and how safely it’s managed in the first week of life.
Boston, MassachusettsAges Up to 2 years - NCT02747303RecruitingPhase 2
Focused radiation for 1 to 5 brain metastases without surgery
This Phase 2 study tests a precise, no-head-frame radiation technique to treat brain metastases. It may help by aiming radiation tightly at the tumors while limiting exposure to nearby healthy brain.
Chicago, IllinoisAges 18 years+ - NCT02824731Recruiting
Proton vs photon radiation for certain brain tumors
This study compares two types of radiation—protons and photons (X-rays)—for specific brain tumors or tumor returns. It aims to see which approach works best and is safest for you, based on how much and where the radiation is delivered.
DresdenAges 18 years+ - NCT02920788Recruiting
Rehab program study for mild traumatic brain injury symptoms
This trial studies whether a specific rehabilitation program (“GOALS”) helps veterans with mild traumatic brain injury (TBI) who still have thinking or memory problems. It compares the program to usual care, using regular assessments and training over time.
San Francisco, CaliforniaAges 18 years+ - NCT03286335Recruiting
Proton radiation for slow-growing or benign brain tumors
This trial studies proton radiation therapy for adults with certain benign or slow-growing brain tumors. It aims to see how well tumors can be controlled, and how treatment affects quality of life and side effects.
Boston, MassachusettsAges 18 years+ - NCT03325946Recruiting
Neuromotor research clinic for people with movement problems
This study is looking at people who have difficulties with movement or muscle control (neuromotor impairment). It may help researchers better understand these problems and improve future care.
Roanoke, VirginiaAges 3 months–18 years - NCT03184038Recruiting
Testing brain function in people with brain metastases after radiosurgery
This study looks at how well your thinking and memory work after treatment with radiosurgery for brain metastases. It may help researchers understand which patients benefit best and how to monitor side effects on brain function.
Sewell, New JerseyAges 18 years+ - NCT07677046Enrolling by invitation
Combination therapy for complex dissociative disorder
This trial studies a therapy called Deep Brain Reorienting (DBR) combined with group sessions for people with complex dissociative disorder, such as dissociative identity disorder (DID) or other specified dissociative disorder (OSDD). The goal is to help process trauma in a safe and supportive setting.
Oslo, OsloAges 18 years+ - NCT03241732Enrolling by invitation
PET-MRI scan study for ongoing brain injury symptoms
This trial uses special brain scans (PET and MRI) to study chronic symptoms after a past traumatic brain injury (TBI), such as memory trouble, mood changes, and headaches. It may help researchers understand what’s going on in the brain and how it relates to symptoms like anxiety or distress.
Philadelphia, PennsylvaniaAges 18–80 - NCT02402426Enrolling by invitation
Online brain health registry for adults
This study is building an online registry where adults can share information to help researchers find people for future brain research. Joining may help future studies get the people they need.
San Francisco, CaliforniaAges 18 years+ - NCT02769416Enrolling by invitation
Testing new treatments for spinal cord and brain injuries
This study looks for ways to test treatments for people with spinal cord injuries and/or brain injuries. It may help researchers better understand which treatment approaches work and for whom.
Houston, TexasAges 18 years+ - NCT00593203Enrolling by invitation
Share a brain tissue sample during surgery
This study collects a small piece of brain tissue during people’s planned brain surgery. It may help researchers learn more about brain conditions and improve future care.
Nashville, TennesseeAges Any age - NCT07411690Recruiting
Spinal fluid leak after brain tumor surgery
This trial checks for spinal fluid leaks after surgery to remove brain tumors. If you are having a planned first-time surgery for a tumor in the upper part of the brain, you may be eligible.
WarsawAges 18 years+ - NCT07413562Recruiting
Nerve stimulation for memory problems after brain injury
This trial tests whether stimulating a nerve in the wrist (median nerve) can help improve thinking and memory problems in people who have had a recent traumatic brain injury. It is for adults with moderate injuries who have trouble with memory and thinking.
Beijing, Beijing MunicipalityAges 18–64 - NCT07413796Recruiting
Comparing skin closure methods in brain tumor surgery
This study compares two ways to close the skin after brain tumor surgery: a continuous stitch under the skin versus separate stitches through the skin. The goal is to see which method leads to better healing and appearance.
Warsaw, Masovian VoivodeshipAges 18 years+ - NCT07413900Recruiting
Brain injury study for babies and toddlers
This study looks at biomarkers (biological signs) in infants who had a brain injury around birth or were born very early, and compares them with healthy babies. The goal is to learn more about brain injuries and recovery.
Madison, WisconsinAges 3 months–2 years - NCT07418775Recruiting
Meningioma Study: Genes, Health & Life
This study looks at how your tumor's genes, personal health habits, and other factors affect your long-term health after a meningioma diagnosis. You'll be asked to complete surveys about your health and experiences—no new treatments or procedures are involved.
San Francisco, CaliforniaAges 18 years+ - NCT07420543Recruiting
Liquid biopsy during brain tumor surgery with 5-ALA
This trial is studying whether a 'liquid biopsy' (a blood test) can help guide brain tumor surgery. It uses a special dye called 5-ALA to help surgeons see the tumor during surgery, and researchers will look for tumor DNA in the blood to see if it matches what is found in the tumor.
MilanAges 18 years+ - NCT07424092RecruitingPhase 2
Virus injection for children with recurrent brain tumors
This trial is testing a virus called DNX-2401, which is injected directly into the tumor, for children and young adults with high-grade brain tumors that have come back or are hard to treat. The goal is to see if this virus can shrink or control the tumor.
UtrechtAges 1–25 - NCT07427563Recruiting
Cerebellar deep brain stimulation for ataxia
This trial tests whether stimulating a part of the brain called the cerebellum with a device can help improve balance and coordination in people with primary ataxia (a movement disorder you were born with or inherited). It aims to see if this treatment is safe and effective over one year.
Toronto, OntarioAges 20–70 - NCT07430150Recruiting
Long-term effects of oxygen therapy on thinking after brain injury
This study checks if hyperbaric oxygen therapy (breathing pure oxygen in a special chamber) has lasting benefits for thinking skills in people who have had a traumatic brain injury.
ZrifinAges 18 years+ - NCT07436754Recruiting
Comparing Two Video Therapy Programs for Emotional Health After Brain Injury
This study compares two different video-based therapy programs to see which one helps people with mild traumatic brain injury who have trouble identifying or managing their emotions. It might be a good fit if you had a concussion at least 6 months ago and have a device for video calls.
Indianapolis, IndianaAges 18 years+
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Common questions
- Are there clinical trials for brain?
- Yes. Clin2 currently lists 2,059 recruiting brain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.